Sensitivity and specificity of self-reported cancer history compared to cancer registry.

2017 ◽  
Vol 35 (8_suppl) ◽  
pp. 234-234 ◽  
Author(s):  
Craig Earle
Keyword(s):  
Sensitivity And Specificity ◽  
Cancer Registry ◽  
Metastatic Potential ◽  
Self Report ◽  
Health Study ◽  
Baseline Survey ◽  
Administrative Claims ◽  
Cancer History ◽  
Match Rate ◽  
Ontario Cancer Registry

234 Background: The Ontario Health Study (OHS) is a large prospective epidemiologic cohort study in which any Ontario resident eighteen years of older may enroll regardless of prior medical history. Baseline data are collected using web-based tools. As part of the consent process, participants are asked for consent to link study data with administrative and health care claims databases, including the Ontario Cancer Registry (OCR). There is an option to enter their Health Insurance Number (HIN) for this purpose. The purpose of this study was to link these data and evaluate the accuracy of self-reported cancer history compared to the cancer registry. Methods: Consenting participants that provided HINs were deterministically linked to the administrative data. Those that did not were probabilistically linked using name, sex and date of birth. Cancer registry records indicating a cancer diagnosed before the date of completion of the OHS baseline survey were considered the gold standard. Concordance, sensitivity, and specificity were assessed. Results: OHS records were successfully linked to administrative claims data and the Ontario Cancer Registry (OCR) with an 85.13% match rate. The final cohort consisted of 139,798 participants. A personal history of cancer was reported by 13,171 of these subjects, out of which 10,066 were found with a record in the OCR. The sensitivity of self-report was 77% and the specificity 95%. Excluding cancers diagnosed after the completion of the baseline survey increased sensitivity of self-report to 93%. The main area of discrepancy causing low sensitivity was the self-reporting of non-melanomatous skin cancers in the OHS questionnaire. Conclusions: While some self-over-reporting of cancer history may occur, cancers with lower metastatic potential tend to be under-captured in our provincial cancer registry. These findings have implications for cohort creation for research and quality improvement.

Validity of self-reported cancer history in the health examinees (HEXA) study: A comparison of self-report and cancer registry records

2017 ◽  
Vol 50 ◽  
pp. 16-21 ◽  
Author(s):  
Sooyoung Cho ◽  
Aesun Shin ◽  
Daesub Song ◽  
Jae Kyung Park ◽  
Yeonjung Kim ◽  
...  
Keyword(s):  
Cancer Registry ◽  
Self Report ◽  
Cancer History

scholarly journals Predictors of incident epilepsy in older adults

Neurology ◽  
2017 ◽  
Vol 88 (9) ◽  
pp. 870-877 ◽  
Author(s):  
Hyunmi Choi ◽  
Alison Pack ◽  
Mitchell S.V. Elkind ◽  
W.T. Longstreth ◽  
Thanh G.N. Ton ◽  
...  
Keyword(s):  
Older Adults ◽  
The United States ◽  
Incidence Rates ◽  
Cox Proportional Hazards ◽  
Self Report ◽  
Health Study ◽  
Cardiovascular Health Study ◽  
Administrative Claims ◽  
History Of

Objective:To determine the prevalence, incidence, and predictors of epilepsy among older adults in the Cardiovascular Health Study (CHS).Methods:We analyzed data prospectively collected in CHS and merged with data from outpatient Medicare administrative claims. We identified cases with epilepsy using self-report, antiepileptic medication, hospitalization discharge ICD-9 codes, and outpatient Medicare ICD-9 codes. We used Cox proportional hazards regression to identify factors independently associated with incident epilepsy.Results:At baseline, 42% of the 5,888 participants were men and 84% were white. At enrollment, 3.7% (215 of 5,888) met the criteria for prevalent epilepsy. During 14 years of follow-up totaling 48,651 person-years, 120 participants met the criteria for incident epilepsy, yielding an incidence rate of 2.47 per 1,000 person-years. The period prevalence of epilepsy by the end of follow-up was 5.7% (335 of 5,888). Epilepsy incidence rates were significantly higher among blacks than nonblacks: 4.44 vs 2.17 per 1,000 person-years (p < 0.001). In multivariable analyses, risk of incident epilepsy was significantly higher among blacks compared to nonblacks (hazard ratio [HR] 4.04, 95% confidence interval [CI] 1.99–8.17), those 75 to 79 compared to those 65 to 69 years of age (HR 2.07, 95% CI 1.21–3.55), and those with history of stroke (HR 3.49, 95% CI 1.37–8.88).Conclusions:Epilepsy in older adults in the United States was common. Blacks, the very old, and those with history of stroke have a higher risk of incident epilepsy. The association with race remains unexplained.

scholarly journals Self-reported Diagnosis of Rheumatoid Arthritis or Ankylosing Spondylitis Has Low Accuracy: Data from the Nord-Trøndelag Health Study

2017 ◽  
Vol 44 (8) ◽  
pp. 1134-1141 ◽  
Author(s):  
Vibeke Videm ◽  
Ranjeny Thomas ◽  
Matthew A. Brown ◽  
Mari Hoff
Keyword(s):  
Rheumatoid Arthritis ◽  
Ankylosing Spondylitis ◽  
Population Based ◽  
Self Report ◽  
Health Study ◽  
Primary Study ◽  
Case File ◽  
Norwegian Population ◽  
Case Files ◽  
Accuracy Data

Objective.Self-reported diagnoses of inflammatory arthritis are not accurate. The primary study aim was to ascertain self-reported diagnoses of rheumatoid arthritis (RA) and ankylosing spondylitis (AS) in the Norwegian population-based Nord-Trøndelag Health Study (HUNT) using hospital case files. The secondary aim was to provide updated estimates of the prevalence and incidence of RA and AS.Methods.All inhabitants ≥ 20 years old from the county of Nord-Trøndelag were invited. Data from 70,805 unique participants from HUNT2 (1995–1997) and HUNT3 (2006–2008) were included. For participants who self-reported RA or AS, case files from all 3 hospitals in the catchment area were evaluated using standardized diagnostic criteria.Results.Of 2703 self-reported cases of RA, 19.1% were verified in hospital files. Of 1064 self-reported cases of AS, 15.8% were verified. Of 259 cases self-reporting both RA and AS, 8.1% had RA and 5.4% had AS. Overall, a self-report of 1 or both diagnoses could not be verified in 82.1%, including 22.8% with insufficient information or no case file. The prevalence of RA was 768 (95% CI 705–835) per 100,000. The incidence of RA from HUNT2 to HUNT3 was 0.48 (0.41–0.56) per 1000 per year. The prevalence of AS was 264 (228–305) per 100,000. The incidence of AS from HUNT2 to HUNT3 was 0.19 (0.15–0.24) per 1000 per year.Conclusion.Self-reported diagnoses of RA and AS are often false-positive. The prevalence and incidence of RA were comparable to reports from similar populations. The incidence of AS was higher than previously reported in a mixed population from Norway.

scholarly journals The Role of Stress in Understanding Differences in Sedentary Behavior in Hispanic/Latino Adults: Results From the Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study

2016 ◽  
Vol 13 (3) ◽  
pp. 310-317 ◽  
Author(s):  
Elizabeth Vásquez ◽  
Garrett Strizich ◽  
Linda Gallo ◽  
Simon J. Marshall ◽  
Gina C. Merchant ◽  
...  
Keyword(s):  
Community Health ◽  
Sedentary Behavior ◽  
Stress Reduction ◽  
Self Report ◽  
Health Study ◽  
Sedentary Behaviors ◽  
Ancillary Study ◽  
Hispanic Community ◽  
Latino Adults ◽  
Sedentary Activities

Background:Chronic stress and/or lifetime traumatic stress can create a self-reinforcing cycle of unhealthy behaviors, such as overeating and sedentary behavior, that can lead to further increases in stress. This study examined the relationship between stress and sedentary behavior in a sample of Hispanic/Latino adults (N = 4244) from the Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study.Methods:Stress was measured as the number of ongoing difficulties lasting 6 months or more and as lifetime exposure to traumatic events. Sedentary behavior was measured by self-report and with accelerometer. Multivariable regression models examined associations of stress measures with time spent in sedentary behaviors adjusting by potential confounders.Results:Those who reported more than one chronic stressor spent, on average, 8 to 10 additional minutes per day in objectively measured sedentary activities (P < .05), whereas those with more than one lifetime traumatic stressor spent (after we adjusted for confounders) 10 to 14 additional minutes in sedentary activities (P < .01) compared with those who did not report any stressors. Statistical interactions between the 2 stress measures and age or sex were not significant.Conclusion:Interventions aimed at reducing sedentary behaviors might consider incorporating stress reduction into their approaches.

scholarly journals Pilot Evaluations of Two Bluetooth Contact Tracing Approaches on a University Campus: Mixed Methods Study (Preprint)

2021 ◽  
Author(s):  
Tyler Shelby ◽  
Tyler Caruthers ◽  
Oren Y Kanner ◽  
Rebecca Schneider ◽  
Dana Lipnickas ◽  
...  
Keyword(s):  
Mixed Methods ◽  
Mobile Phone ◽  
Sensitivity And Specificity ◽  
Mobile App ◽  
Mixed Methods Study ◽  
Self Report ◽  
Contact Tracing ◽  
Free Text ◽  
Contact Interactions ◽  
University Campus

BACKGROUND Many have proposed the use of Bluetooth technology to help scale up contact tracing for COVID-19. However, much remains unknown about the accuracy of this technology in real-world settings, the attitudes of potential users, and the differences between delivery formats (mobile app vs carriable or wearable devices). OBJECTIVE We pilot tested 2 separate Bluetooth contact tracing technologies on a university campus to evaluate their sensitivity and specificity, and to learn from the experiences of the participants. METHODS We used a convergent mixed methods study design, and participants included graduate students and researchers working on a university campus during June and July 2020. We conducted separate 2-week pilot studies for each Bluetooth technology. The first was for a mobile phone app (“app pilot”), and the second was for a small electronic “tag” (“tag pilot”). Participants validated a list of Bluetooth-identified contacts daily and reported additional close contacts not identified by Bluetooth. We used these data to estimate sensitivity and specificity. Participants completed a postparticipation survey regarding appropriateness, usability, acceptability, and adherence, and provided additional feedback via free text. We used tests of proportions to evaluate differences in survey responses between participants from each pilot, paired <i>t</i> tests to measure differences between compatible survey questions, and qualitative analysis to evaluate the survey’s free-text responses. RESULTS Among 25 participants in the app pilot, 53 contact interactions were identified by Bluetooth and an additional 61 by self-report. Among 17 participants in the tag pilot, 171 contact interactions were identified by Bluetooth and an additional 4 by self-report. The tag had significantly higher sensitivity compared with the app (46/49, 94% vs 35/61, 57%; <i>P</i>&lt;.001), as well as higher specificity (120/126, 95% vs 123/141, 87%; <i>P</i>=.02). Most participants felt that Bluetooth contact tracing was appropriate on campus (26/32, 81%), while significantly fewer participants felt that using other technologies, such as GPS or Wi-Fi, was appropriate (17/31, 55%; <i>P</i>=.02). Most participants preferred technology developed and managed by the university rather than a third party (27/32, 84%) and preferred not to have tracing apps on their personal phones (21/32, 66%), due to “concerns with privacy.” There were no significant differences in self-reported adherence rates across pilots. CONCLUSIONS Convenient and carriable Bluetooth technology may improve tracing efficiency while alleviating privacy concerns by shifting data collection away from personal devices. With accuracy comparable to, and in this case, superior to, mobile phone apps, such approaches may be suitable for workplace or school settings with the ability to purchase and maintain physical devices.

scholarly journals Prospective predictors of sustainment of multiple EBPs in a system-driven implementation context: Examining sustained delivery based on administrative claims

2021 ◽  
Vol 2 ◽  
pp. 263348952110578
Author(s):  
Anna S. Lau ◽  
Teresa Lind ◽  
Mojdeh Motamedi ◽  
Joyce H. L. Lui ◽  
Mary Kuckertz ◽  
...  
Keyword(s):  
Large Scale ◽  
Organizational Context ◽  
Scale Up ◽  
Volume Ratio ◽  
Organizational Factors ◽  
Self Report ◽  
Administrative Claims ◽  
Sustained Delivery ◽  
Cross Sectional ◽  
Program Leaders

Background System-driven scale-up of multiple evidence-based practices (EBPs) is an increasingly common method used in public mental health to improve care. However, there are little data on the long-term sustained delivery of EBPs within these efforts, and previous studies have relied on retrospective self-report within cross-sectional studies. This study identified prospective predictors of sustained EBP delivery at the EBP-, therapist-, and organizational-levels using survey and administrative claims data within a large-scale system-driven implementation effort. Methods 777 therapists and 162 program leaders delivering at least one of six EBPs of interest completed surveys assessing perceptions of EBPs and organizational context. These surveys were linked to administrative data to examine prospective predictors of therapists’ EBP delivery over 33 months. Results Five of the six EBPs implemented showed sustained delivery in the system, with volume varying by EBP. Although total EBP claim volume per therapist decreased over time, the volume ratio (ratio of EBP-specific claims to total EBP and non-EBP claims) stayed relatively stable. Multilevel models revealed that EBPs that required consultation, had unstructured content, higher therapist self-efficacy with the EBP, and more positive program leader perceptions of the EBP were associated with greater sustained volume and volume ratio of the EBP. Therapists who were trained in fewer EBPs, who were unlicensed, and who worked in agencies rated by program leaders as lower on organizational staff autonomy and stress showed greater sustained EBP volume and volume ratio. Finally, more direct service hours per week provided by therapist predicted greater sustained EBP volume, but lower volume ratio. Conclusions The results point to the importance of EBP, therapist, and organizational factors that may be targeted in implementation strategies to promote the sustainment of EBPs.

Abstract P071: Association of Baseline Depressive Symptoms With 6-Year Incidence of Diabetes in the Hispanic Community Health Study/Study of Latinos

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Matthew J O'Brien ◽  
Mercedes R Carnethon ◽  
Frank J Penedo ◽  
Karen M Tabb ◽  
Sylvia Wassertheil-Smoller ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Community Health ◽  
Self Report ◽  
Incident Diabetes ◽  
Health Study ◽  
Incidence Density ◽  
Diabetes Incidence ◽  
Central Americans ◽  
Hispanic Community ◽  
Latino Adults

Background: Among Hispanics/Latinos, there is substantial heterogeneity in the prevalence of depressive symptoms and diabetes by background. This study aimed to examine the association between depressive symptoms and incident diabetes among Hispanic/Latino adults of diverse backgrounds. Methods: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) is a prospective, community-based study of 16,415 self-identified Hispanic/Latino adults aged 18-74 years at Visit 1 (2008-2011) and 10,914 who have also completed the Visit 2 examination by August 2017. This analysis includes 8,804 participants who were free from diabetes at baseline and attended both Visits. Baseline depressive symptoms were assessed using the CES-D 10-item depression scale and divided into quartiles. Incident diabetes was defined by fasting glucose ≥126mg/dL, 2-hour postload glucose 140-199mg/dL, HbA1c ≥6.5%, or self-report. Accounting for HCHS/SOL complex survey design, we used Poisson regression models to estimate diabetes incidence density ratios (Table). Results: Baseline BMI was associated with both depressive symptoms and incident diabetes. Overall, 876 participants developed diabetes. In analyses stratified by Hispanic/Latino background, the association between baseline depressive symptoms and incident diabetes was significant for South Americans, Central Americans, and Mexicans. No significant associations between depressive symptoms and diabetes were seen among Hispanics/Latinos of Dominican, Cuban, or Puerto Rican backgrounds. Conclusions: These findings suggest that the association between depressive symptoms and incident diabetes in Hispanics/Latinos may differ by their background, with South and Central Americans at the highest risk. This difference may be partly explained by variation in participants’ understanding of CES-D questions by Hispanic/Latino background. Future research is needed to understand these novel findings fully and explore their implications for practice and policy.

Factors Affecting the Use of Palliative Radiotherapy in Ontario

2001 ◽  
Vol 19 (1) ◽  
pp. 137-144 ◽  
Author(s):  
J. Huang ◽  
S. Zhou ◽  
P. Groome ◽  
S. Tyldesley ◽  
J. Zhang-Solomans ◽  
...  
Keyword(s):  
Cancer Registry ◽  
Palliative Radiotherapy ◽  
Cancer Center ◽  
Factors Affecting ◽  
Cancer Centers ◽  
Factors Associated ◽  
Cancer Registry Data ◽  
Barriers To Access ◽  
Ontario Cancer Registry ◽  
Primary Measure

PURPOSE: To describe the use of palliative radiotherapy (PRT) and to identify factors associated with the use of PRT. MATERIALS AND METHODS: The Ontario Cancer Registry was used to identify 193,253 adult patients who died of cancer between 1986 and 1995. Radiotherapy records from all Ontario cancer centers and the data on socioeconomic status (SES) from the Canadian Census were linked to the Ontario Cancer Registry data. The proportion of cases who received at least one course of PRT at any time within 2 years of death (PRT2Y) was used as a primary measure of the use rate of PRT. RESULTS: Overall, 26.4% of cases underwent at least one course of PRT. PRT2Y remained relatively constant over the study period. PRT2Y was disease-specific and ranged from 4% for pancreatic cancer to 41% for prostate cancer. Age was negatively associated with PRT2Y (adjusted odds ratio [OR], 4.5 for the youngest group), and SES was positively associated with PRT2Y (adjusted OR, 1.2 for patients from wealthy communities). Patients who were initially diagnosed in a hospital affiliated with a cancer center (adjusted OR, 1.4) or who lived in a county in which a cancer center is located (adjusted OR, 1.2), or who resided in certain regions (adjusted OR, 1.20 for Hamilton and 1.17 for Kingston), were more likely to be treated with PRT. CONCLUSION: The use of PRT varied across the dispersed population in Ontario and was influenced by factors unrelated to the patient’s needs. An effort should be made to reduce barriers to access for disadvantaged groups.

scholarly journals Does the Strengths and Difficulties Questionnaire – self report yield invariant measurements across different nations? Data from the International Child Mental Health Study Group

2014 ◽  
Vol 24 (4) ◽  
pp. 323-334 ◽  
Author(s):  
D. Stevanovic ◽  
R. Urbán ◽  
O. Atilola ◽  
P. Vostanis ◽  
Y. P. Singh Balhara ◽  
...  
Keyword(s):  
Measurement Invariance ◽  
Conduct Problems ◽  
Factor Model ◽  
Five Factor Model ◽  
Strengths And Difficulties Questionnaire ◽  
Self Report ◽  
Health Study ◽  
Prosocial Behaviour ◽  
Emotional Symptoms ◽  
Strengths And Difficulties

Aims.This study evaluated the measurement invariance of the strengths and difficulties questionnaire (SDQ) self-report among adolescents from seven different nations.Methods.Data for 2367 adolescents, aged 13–18 years, from India, Indonesia, Nigeria, Serbia, Turkey, Bulgaria and Croatia were available for a series of factor analyses.Results.The five-factor model including original SDQ scales emotional symptoms, conduct problems, hyperactivity–inattention problems, peer problems and prosocial behaviour generated inadequate fit degree in all countries. A bifactor model with three factors (i.e., externalising, internalising and prosocial) and one general problem factor yielded adequate degree of fit in India, Nigeria, Turkey and Croatia. The prosocial behaviour, emotional symptoms and conduct problems factor were found to be common for all nations. However, originally proposed items loaded saliently on other factors besides the proposed ones or only some of them corresponded to proposed factors in all seven countries.Conclusions.Due to the lack of a common acceptable model across all countries, namely the same numbers of factors (i.e., dimensional invariance), it was not possible to perform the metric and scalar invariance test, what indicates that the SDQ self-report models tested lack appropriate measurement invariance across adolescents from these seven nations and it needs to be revised for cross-country comparisons.

scholarly journals Development of Query Strategies to Identify a Histologic Lymphoma Subtype in a Large Linked Database System

2007 ◽  
Vol 3 ◽  
pp. 117693510700300 ◽  
Author(s):  
Michael Graiser ◽  
Susan G. Moore ◽  
Rochelle Victor ◽  
Ashley Hilliard ◽  
Leroy Hill ◽  
...  
Keyword(s):  
Follicular Lymphoma ◽  
Sensitivity And Specificity ◽  
Cancer Registry ◽  
Medical Records ◽  
Patient Population ◽  
Registry Data ◽  
Free Text ◽  
Cancer Registry Data ◽  
Medical Reports ◽  
Lymphoma Subtype

Background Large linked databases (LLDB) represent a novel resource for cancer outcomes research. However, accurate means of identifying a patient population of interest within these LLDBs can be challenging. Our research group developed a fully integrated platform that provides a means of combining independent legacy databases into a single cancer-focused LLDB system. We compared the sensitivity and specificity of several SQL-based query strategies for identifying a histologic lymphoma subtype in this LLDB to determine the most accurate legacy data source for identifying a specific cancer patient population. Methods Query strategies were developed to identify patients with follicular lymphoma from a LLDB of cancer registry data, electronic medical records (EMR), laboratory, administrative, pharmacy, and other clinical data. Queries were performed using common diagnostic codes (ICD-9), cancer registry histology codes (ICD-O), and text searches of EMRs. We reviewed medical records and pathology reports to confirm each diagnosis and calculated the sensitivity and specificity for each query strategy. Results Together the queries identified 1538 potential cases of follicular lymphoma. Review of pathology and other medical reports confirmed 415 cases of follicular lymphoma, 300 pathology-verified and 115 verified from other medical reports. The query using ICD-O codes was highly specific (96%). Queries using text strings varied in sensitivity (range 7–92%) and specificity (range 86–99%). Queries using ICD-9 codes were both less sensitive (34–44%) and specific (35–87%). Conclusions Queries of linked-cancer databases that include cancer registry data should utilize ICD-O codes or employ structured free-text searches to identify patient populations with a precise histologic diagnosis.

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