Experience and outcomes of the Acute Leukemia Shared-Care Program.

184 Background: Acute leukemia (AL) is a rapidly progressive disease requiring timely and intensive treatment. Historically, care for approximately 50% of AL patients in Ontario, Canada has been centralized resulting in significant resource pressures at the specialized center and travel pressures on patients and caregivers. The AL Shared-Care Program was launched in 2014 to enable delivery of appropriate portions of care at an AL Service Site and Partner Cancer Center closer to the patient’s home. Methods: The impact of the Program was evaluated through provider interviews (n = 22) and the Patient Experience Survey which included 20 non-shared-care (control) and 26 shared-care (intervention) patients. A retrospective analysis of 332 control and 70 intervention patients was used to evaluate the Program’s impact on travel, survival outcomes, and resource utilization. Results: Retrospective analysis revealed that an average intervention group patient saved a median round trip travel distance of 115 km [IQR: 88-179] and time of 91 min [IQR: 62-141]. 91% of health care providers reported that the Program provided person-centered care. Patients reported positive experiences with no statistically significant differences between the intervention and control groups in coordination of care (81% vs 90%, p = 0.39), overall care (88% vs 100%, p = 0.12), and experience (85% vs 90%, p = 0.60). There was no statistically significant correlation between patient satisfaction scores and patient-reported health status (r = 0.10, p = 0.51) and state of health (r = 0.03, p = 0.87). There was no significant difference in survival between groups (HR = 0.73, 95% CI [0.49, 1.13], p = 0.16). Finally, system cost estimated based on emergency department visits, admissions for febrile neutropenia, and follow-up clinic visits showed that there was no statistically significant difference in average monthly cost per patient between the intervention and control groups ($943 vs $1,197 respectively, p = 0.48). Conclusions: The AL Shared-Care Program reduced the travel burden for patients and caregivers without negatively impacting provider and patient experience, survival and system costs. Findings of this work will support the expansion of the Program to additional sites.

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457 The Impact of PAP Therapy on Hematocrit in OSA and Polycythemia: A Pilot Study

SLEEP ◽

10.1093/sleep/zsab072.456 ◽

2021 ◽

Vol 44 (Supplement_2) ◽

pp. A180-A181

Author(s):

Mustafa Jafri ◽

Gabrielle Rosa-Acosta ◽

Jose Flores Martinez ◽

Elizabeth Schofield ◽

Cy Wilkins ◽

...

Keyword(s):

Intervention Group ◽

Smoking History ◽

Event Analysis ◽

Control Groups ◽

Testosterone Therapy ◽

Obstructive Sleep ◽

Significant Difference ◽

Testosterone Administration ◽

And Control ◽

The Impact

Abstract Introduction Untreated polycythemia leads to complications including thrombosis. Obstructive sleep apnea (OSA) is commonly associated with secondary erythrocytosis, which testosterone therapy can perpetuate. Effects of positive airway pressure (PAP) on elevated hematocrit (HCT) is unknown. We hypothesize PAP adherence can reduce HCT in men with OSA and polycythemia. Methods Retrospective chart review of male outpatients with newly diagnosed OSA and HCT≥45% at or 3 months before polysomnography (PSG) was conducted. Intervention group consisted of patients initiating PAP for OSA. HCT within 6 months of PAP initiation and PSG were recorded for intervention and control groups, respectively. Primary endpoint was time-to-HCT reduction of HCT<50% plus 3% decrease. Cox proportional-hazards analysis was used to assess time-to-HCT response. Demographics, smoking history, testosterone administration, STOP-Bang score, AHI, and PAP compliance data were obtained. Patients excluded if PAP not indicated, or if PSG, PAP compliance, or repeat HCT were unavailable. Results 41 men with OSA had HCT≥45%, of which 16 had HCT≥50%. Median age was 60 years and median BMI was 32 kg/m2. 28 started PAP. 21 met definition for PAP compliance within 6 months. Median AHI of intervention and control groups were 23 and 19 events/hr, respectively. Mean baseline HCT of both groups were 49 and 50, respectively. No significant difference in age, BMI, smoking history, testosterone therapy, and baseline HCT between both groups noted. 39% of intervention group exhibited HCT response at 1 or more longitudinal assessments, versus 38% of control. Intervention group had higher mean STOP-Bang than control (mean 5.9 vs. 4.6, p=0.01) and trended towards higher mean baseline AHI (27.4 vs. 19.0, p= 0.06). Time-to-event analysis controlling for STOP-Bang and AHI demonstrated PAP was not associated with time-to-HCT response (HR = 1.3, 95% CI = 0.4–4.4). In moderate-severe OSA patients, 40% of intervention group had HCT response compared to 14% of control, though difference was not significant (HR = 2.5, 95% CI = 0.3–20.0). Conclusion Moderate-severe OSA patients trended towards reduction in HCT with PAP, although not statistically significant. Testosterone administration did not affect HCT response to PAP in this cohort. Larger studies are required to determine HCT response to PAP in these patients. Support (if any):

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Pilot evaluation of a partner-supported online reading intervention for Grade 3–6 children

Child Language Teaching and Therapy ◽

10.1177/0265659021989400 ◽

2021 ◽

pp. 026565902198940

Author(s):

Jessica Dean ◽

Michelle Pascoe ◽

Jane le Roux

Keyword(s):

Prospective Study ◽

Retrospective Analysis ◽

Reading Intervention ◽

Reading Difficulties ◽

Reading Rate ◽

Control Groups ◽

Reading Accuracy ◽

Significant Difference ◽

Reading Partners ◽

And Control

Information and communication technology (ICT)-based reading interventions have potential to help children with reading difficulties, especially those in resource-constrained environments who otherwise might not have access to support. This pilot study aimed to describe the impact of an online, partner-supported reading intervention designed for South African children with reading difficulties. Objectives were to qualitatively describe participants’ experience of the intervention, and quantitatively evaluate changes in reading accuracy, rate, comprehension and receptive vocabulary after intervention. Two studies were conducted: (1) A retrospective analysis using data from intervention in mainstream Cape Town schools with peers as reading partners; (2) A prospective study in a Cape Town school with special needs educational provision where speech-language therapists served as reading partners. Both studies used matched participant, pre/post intervention designs. A total of 40 children in grades 3 to 6 participated. In each study the intervention group ( n = 20) received intervention 3 times per week (30 minutes per session) for 10 weeks, while the control group ( n = 20) continued with regular school activities. Participants enjoyed the ICT-based intervention, valued the role of the reading partners, believed they had made literacy gains, and reported positive attitudinal and behavioural changes related to reading. Retrospective analysis revealed no statistically significant differences between intervention and control groups. The prospective study found a statistically significant difference between the intervention and control groups’ gains on one measure of reading rate, but no significant difference in reading accuracy, vocabulary or reading comprehension gains. The study provides a preliminary description of one ICT-based reading intervention. Although an intervention effect could not be demonstrated, the changes noted in reading rate together with qualitative findings suggest a need for further research.

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The impact of online learning on student motivation in science and biology classes

Revija za elementarno izobraževanje ◽

10.18690/rei.13.1.73-87.2020 ◽

2020 ◽

Vol 13 (1) ◽

pp. 73-87

Author(s):

Mila Bulić ◽

Ines Blažević

Keyword(s):

Student Motivation ◽

Online Teaching ◽

Natural Sciences ◽

Online Classes ◽

Control Groups ◽

Motivation For Learning ◽

Significant Difference ◽

Study Participants ◽

And Control ◽

The Impact

The research aimed to check for difference in learning motivation between students learning online and students participating in modern classroom instruction. The study participants included students attending grades 5 to 8, divided into experimental (online classes) and control groups based on pre-testing. The results show that there is no statistically significant difference in motivation between the tested sub-samples. Student motivation for learning natural sciences declines with their years of schooling, but this is not statistically significant. It can be concluded that online teaching of Science and Biology as a learning tool can be as motivating as modern teaching using active classroom methods.

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Assessment of anxiety and quality of life in fibromyalgia patients

Sao Paulo Medical Journal ◽

10.1590/s1516-31802004000600005 ◽

2004 ◽

Vol 122 (6) ◽

pp. 252-258 ◽

Cited By ~ 53

Author(s):

Tathiana Pagano ◽

Luciana Akemi Matsutani ◽

Elisabeth Alves Gonçalves Ferreira ◽

Amélia Pasqual Marques ◽

Carlos Alberto de Bragança Pereira

Keyword(s):

Quality Of Life ◽

Outpatient Service ◽

Test Group ◽

Control Group ◽

Control Groups ◽

Sf 36 ◽

Significant Difference ◽

And Control ◽

The Impact

CONTEXT: Fibromyalgia is a syndrome characterized by chronic, diffuse musculoskeletal pain, and by a low pain threshold at specific anatomical points. The syndrome is associated with other symptoms such as fatigue, sleep disturbance, morning stiffness and anxiety. Because of its chronic nature, it often has a negative impact on patients' quality of life. OBJECTIVE: To assess the quality of life and anxiety level of patients with fibromyalgia. TYPE Of STUDY: Cross-sectional. SETTING: Rheumatology outpatient service of Hospital das Clínicas (Medical School, Universidade de São Paulo). METHODS: This study evaluated 80 individuals, divided between test and control groups. The test group included 40 women with a confirmed diagnosis of fibromyalgia. The control group was composed of 40 healthy women. Three questionnaires were used: two to assess quality of life (FIQ and SF-36) and one to assess anxiety (STAI). They were applied to the individuals in both groups in a single face-to-face interview. The statistical analysis used Student's t test and Pearson's correlation test (r), with a significance level of 95%. Also, the Pearson chi-squared statistics test for homogeneity, with Yates correction, was used for comparing schooling between test and control groups. RESULTS: There was a statistically significant difference between the groups (p = 0.000), thus indicating that fibromyalgia patients have a worse quality of life and higher levels of anxiety. The correlations between the three questionnaires were high (r = 0.9). DISCUSSION: This study has confirmed the efficacy of FIQ for evaluating the impact of fibromyalgia on the quality of life. SF-36 is less specific than FIQ, although statistically significant values were obtained when analyzed separately, STAI showed lower efficacy for discriminating the test group from the control group. The test group showed worse quality of life than did the control group, which was demonstrated by both FIQ and SF-36. Even though STAI was a less efficient instrument, it presented significant results, showing that fibromyalgia patients presented higher levels of anxiety, both on the state and trait scales. Thus, patients with fibromyalgia had higher levels of tension, nervousness, preoccupation and apprehension, and higher propensity towards anxiety. CONCLUSION: The three instruments utilized showed efficiency in evaluating fibromyalgia patients. FIQ was found to be the most efficient instrument for discriminating and assessing the impact of fibromyalgia on their quality of life. It can be concluded that such patients have a worse quality of life and higher levels of anxiety.

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Impact of Pharmacy Student and Resident-Led Discharge Counseling on Heart Failure Patients

Journal of Pharmacy Practice ◽

10.1177/0897190013491768 ◽

2013 ◽

Vol 26 (6) ◽

pp. 574-579 ◽

Cited By ~ 30

Author(s):

Andrew Szkiladz ◽

Katherine Carey ◽

Kimberly Ackerbauer ◽

Mark Heelon ◽

Jennifer Friderici ◽

...

Keyword(s):

Heart Failure ◽

Medication Errors ◽

Pharmacy Student ◽

Control Groups ◽

Readmission Rates ◽

Cost Avoidance ◽

Significant Difference ◽

Heart Failure Readmissions ◽

And Control ◽

The Impact

Purpose: Many health systems have implemented interventions to reduce the rate of heart failure readmissions. Pharmacists have the training and expertise to provide effective medication-related education. However, few studies have examined the impact of discharge education provided by pharmacy students and residents on patients hospitalized with heart failure exacerbations. Methods: This was a nonrandomized intervention study evaluating the impact of a pharmacy student and resident-led discharge counseling program on heart failure readmissions. The primary end point was the 30-day heart failure readmission rate. Secondary end points included self-reported patient understanding of medications, number of medication errors documented, and estimated associated cost avoidance. Results: A total of 86 and 94 patients were enrolled into the intervention and control groups, respectively. No statistically significant difference in readmission rates was detected between the intervention and the control groups. Thirty-four medication errors and discrepancies were documented, or 1 for every 2.5 patients counseled, resulting in an estimated cost avoidance of $4241 for the institution. Eighty-nine percent of patients who received discharge counseling agreed they had a better understanding of their medications after speaking with a pharmacy resident or student. Conclusions: There was no statistically significant difference in readmission rates; however, several medication errors were prevented, and a large percentage of patients expressed an improved understanding of their medications.

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The Impact of Dialogic Learning on Students’ Attention and Academic Achievement

Annals of Behavioral Neuroscience ◽

10.18314/abne.v1i1.1215 ◽

2018 ◽

Vol 1 (1) ◽

pp. 47-55

Author(s):

Ali Nouri ◽

Fataneh Esmaeilli ◽

Saman Seifpour ◽

Mahmoud Talkhabi ◽

Anahita Khorami

Keyword(s):

Academic Achievement ◽

Academic Performance ◽

Control Groups ◽

Dialogic Learning ◽

Achievement Data ◽

Significant Difference ◽

The Mean ◽

And Control ◽

The Impact ◽

Experimental Group

This study is a mixed method design which employed both quantitative and qualitative methods in order to investigate the impact of dialogic learning on students’ attention and academic achievement. Data were collected using several instruments, including: the Attention Network Test; academic performance tests and semi-structured interviews. Results of Analysis of Covariance (ANCOVA) indicated that there is a statistically significant difference between the mean scores of students of the experimental and control groups on the executive control in favor of the experimental group after controlling the IQ score and pre-test scores. Further, there is a statistically significant difference between the mean scores of student of the experimental and control groups on the academic achievement tests (except of mathematics) in favor of the experimental group. The qualitative data also supported the quantitative findings. Therefore, dialogic teaching has significantly greater and more positive changes on some aspects of attention and academic performance.

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Home-based tele-rehabilitation presents comparable positive impact on self-reported functional outcomes as usual care: The Singapore Tele-technology Aided Rehabilitation in Stroke randomised trial

Journal of Telemedicine and Telecare ◽

10.1177/1357633x19868905 ◽

2019 ◽

pp. 1357633X1986890

Author(s):

Miho Asano ◽

Bee C Tai ◽

Felicity YT Yeo ◽

Shi C Yen ◽

Arthur Tay ◽

...

Keyword(s):

Usual Care ◽

Functional Outcomes ◽

Positive Impact ◽

Randomised Trial ◽

Intervention Group ◽

Control Groups ◽

Significant Difference ◽

Rehabilitation System ◽

And Control ◽

The Impact

Introduction The aim of this research was to evaluate the impact of a novel tele-rehabilitation system on self-reported functional outcomes compared to usual care during the first three months after stroke. Methods A parallel, two-arm, evaluator-blinded, randomised controlled trial was conducted. Adults aged ≥40 years who had suffered a stroke within four weeks of the start of the study were recruited from the general community. The intervention group received access to a novel tele-rehabilitation system and programme for three months. The primary outcome measures utilised were the frequency and limitation total scores of the Late-Life Function and Disability Instrument (LLFDI) at three months. Results A total of 124 individuals were recruited. The mean differences in the LLDFI frequency and limitation total scores at three months comparing the intervention and control groups were –3.30 (95% confidence interval (CI) –7.81 to 1.21) and –6.90 (95% CI –15.02 to 1.22), respectively. Adjusting for the respective baseline covariates and baseline Barthel Index also showed no significant difference between interventions in the LLFDI outcomes. Discussion The intervention and control groups self-reported similar improvements in functional outcomes. Tele-rehabilitation may be a viable option to provide post-stroke rehabilitation services in Singapore while reducing barriers to continue rehabilitation conventionally after discharge from hospital and encouraging more participation.

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Effect of Verbal Feedback on Dribbling Skill in Basketball During The Eight Weeks Training

10.53350/pjmhs2115113349 ◽

2021 ◽

Vol 15 (11) ◽

pp. 3349-3351

Author(s):

Ibrahim Efe Etiler ◽

Turhan Toros

Keyword(s):

Test Group ◽

Skill Learning ◽

Control Group ◽

Verbal Feedback ◽

Control Groups ◽

Significant Difference ◽

Post Test ◽

Research Findings ◽

And Control ◽

The Impact

Purpose of this study is to examine the impact of verbal feedbacks given to the player during trainings on the basketball dribbling. The study is performed with total 40 students in two groups having similarities in terms of various factors and having education in Toros University in 2016-2017 academic year. The average age of the research group is (20.87 ± 1.61) for the test group and (20.60 ± 1.09) for the control group. Dribbling Evaluation Form, whose validity and reliability study was conducted by Çamur3 was used as data collection tool. In the data analysis, Shapiro-Wilk test was used to determine whether the scores show normal distribution or not. The Wilcoxon Signed Ranks Test was used to determine the difference between the pre-test and post-test scores of the groups. In the study, 0.05 was used in statistical processes as the level of significance. According to the research findings, there was a significant difference between the test group's pre-test and post-test dribbling values (p <0.05). The Mann-Whitney U Test was used to determine the differences between test and control groups. According to the research findings, a significant difference was found between the test and control groups' post-test dribbling values (p <0.05). As a result, it was observed that verbal feedback during eight weeks of training had a positive effect on dribbling. Keywords: Dribbling, Skill Learning, Basketball, Feedback, Verbal Feedback

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Closed Captioned

10.4018/978-1-7998-8028-8.ch011 ◽

2022 ◽

pp. 185-212

Author(s):

Timothy Hinchman

Keyword(s):

Preservice Teachers ◽

Cognitive Diversity ◽

Inferential Statistics ◽

Control Groups ◽

New Yorker ◽

Significant Difference ◽

Diverse World ◽

And Control ◽

The Impact

This chapter investigates the constraints impact on the creativity of millennial preservice teachers when captioning a New Yorker Magazine cartoon. According to research, millennials have a decreased capacity for unique ideas, synthesis, articulation, and open-mindedness, which limits their ability to function in a diverse world. The study examined the topic using the constraint-based model of novelty (C-BMN; creativity problem, constraints, variability, and problem spaces) as a framework, as well as the new rubric, which assessed data on the impact of constraints on creativity among 90 millennial PST. Inferential statistics were used to compare differences in creativity, and the results indicated a statistically significant difference in total caption creativity between the experimental and control groups. The study corroborated previous research, concluding that constraints foster creativity. The findings of this study have implications for stakeholders interested in incorporating constraint-based strategies to increase cognitive diversity.

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Impact of Genetic Polymorphism of Sulpha Transferase Genes (SULT1A) Genes on the Risk of Females with Breast Cancer in Jordan

10.20944/preprints201710.0050.v2 ◽

2018 ◽

Author(s):

Mona Bustami ◽

Abdel-Ellah Al-Shudifat ◽

Nagham Hussein ◽

Mohannad Yacoub ◽

Eiad Atwa ◽

...

Keyword(s):

Breast Cancer ◽

Sanger Sequencing ◽

Breast Cancer Incidence ◽

Control Groups ◽

Allele Distribution ◽

Significant Difference ◽

Pcr Rflp ◽

Endogenous Compounds ◽

And Control ◽

The Impact

Sulfotransferases (SULTs) family plays a significant role in the biotransformation of a variety of xenobiotics and endogenous compounds by which carcinogenesis and mutagenicity of different malignancies are increasingly affected. Recent data identified various genetically polymorphic SULTs enzymes with significant variations in the enzyme activity. This study aimed to investigate the impact of SULT1A1 gene polymorphism and and its potential risk on females with breast cancer in Jordan using a PCR-RFLP and Sanger Sequencing methods. The analysis showed that 24.7% of the patients and 25.3% of the controls were homozygous for the SULT1A1*1 allele (SULT1A1*1/SULT1A1*1) compared to 8.8% and 5.7% homozygous for the SULT1A1*2 allele (SULT1A1*2/SULT1A1*2) for patients and controls respectively. Most of the patients and controls were heterozygous for SULT1A1*1 allele (SULT1A1*1/SULT1A1*2) with rates of 66.5% and 69.0% in patients and controls respectively. In addition, the frequencies of the mutant SULT1A1*2 allele were 0.42 and 0.4 in the patient and control groups respectively. No significant difference in genotype and allele distribution was noted between the breast cancer and control groups. The risk of breast cancer in individuals carrying the SULT1A1*2 allele was determined by combining the SULT1A1*1/SULT1A1*2 and ULT1A1*2/SULT1A1*2 genotypes. No association was observed between SULT1A1 polymorphism and breast cancer incidence (P = 0.63; OR, 0.93; 95% CI, 0.68–1.26). However, SULT1A1*2 allele was found to increase the risk of breast cancer by 1.26-fold.

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