scholarly journals Knowledge Summaries for Comprehensive Breast Cancer Control

2018 ◽  
pp. 1-7 ◽  
Author(s):  
Jo Anne Zujewski ◽  
Allison L. Dvaladze ◽  
Andre Ilbawi ◽  
Benjamin O. Anderson ◽  
Silvana Luciani ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Clinical Care ◽  
Breast Cancer Mortality ◽  
Cancer Control ◽  
Integrated Approach ◽  
Evidence Based ◽  
Low Resource Settings ◽  
Low Resource ◽  
Four Levels ◽  
Breast Cancer Control

Breast cancer is the most common cancer in women worldwide, affecting > 1.6 million women each year, projected to increase to 2.2 million cases annually by 2025. A disproportionate number of the > 500,000 women who die as a result of breast cancer each year reside in low-resource settings. Breast cancer control is an important component of cancer control planning and women’s health programs, and tools are needed across the care continuum to reduce the cancer burden, especially in low-resource settings. Cancer control planning is complex and multifaceted. Evidence shows that outcomes are improved when prevention, early diagnosis, treatment, and palliation are integrated and synchronously developed within a country/region’s health plan. The Knowledge Summaries for Comprehensive Breast Cancer Control are the product of a multiyear collaboration led by the Union for International Cancer Control, Breast Health Global Initiative, Pan American Health Organization, and Center for Global Health of the US National Cancer Institute. Fourteen knowledge summaries distilled from evidence-based, resource-stratified guidelines, and aligned with WHO guidance on breast cancer control, build a framework for resource prioritization pathways and delivery systems for breast cancer control at four levels of available resources: basic, limited, enhanced, and maximal. Each summary contains relevant content to inform breast cancer policy, clinical care, and advocacy, aiding in the development and implementation of policies and programs. These tools provide a common platform for stakeholders, including policymakers, administrators, clinicians, and advocates to engage in decision making appropriate to their local setting. The goal is to facilitate evidence-based policy actions and urgently advance implementation of an integrated approach to reduce breast cancer mortality and improve quality of life.

scholarly journals Challenges, Opportunities, and Priorities for Advancing Breast Cancer Control in Zambia: A Consultative Meeting on Breast Cancer Control

2019 ◽  
pp. 1-7 ◽  
Author(s):  
Anna Cabanes ◽  
Sharon Kapambwe ◽  
Susan Citonje-Msadabwe ◽  
Groesbeck P. Parham ◽  
Kennedy Lishimpi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Early Detection ◽  
Breast Cancer Mortality ◽  
Cancer Control ◽  
Control Program ◽  
Cervical Cancer Prevention ◽  
National Guidelines ◽  
National Breast ◽  
National Priority ◽  
Breast Cancer Control

In 2016, the Zambian government made cancer control a national priority and released a National Cancer Control Strategic Plan for 2016 to 2021, which focuses on malignancies of the breast, cervix, and prostate, and retinoblastoma. The plan calls for a collective reduction in the cancer burden by 50%. In support of this vision, Susan G. Komen sponsored a consultative meeting in Lusaka, Zambia, in September 2017 to bring together the country’s main breast cancer stakeholders and identify opportunities to improve breast cancer control. The recommendations generated during the discussions are presented. There was general agreement that the first step toward breast cancer mortality reduction should consist of implementation of early detection service platforms focused on women who are symptomatic. Participants also agreed that the management of all components of the national breast cancer control program should be integrated and led by the Ministry of Health. As much as possible, early detection and treatment services presently offered by the Cervical Cancer Prevention Program of Zambia and Cancer Diseases Hospital should be leveraged. Efforts are under way through multiple stakeholders to implement the following recommendations: development of national guidelines for the early diagnosis of breast cancer, training of breast surgeons, implementation of early detection and surgical treatment service platforms at the district-hospital level, and epidemiologic research, including the improvement of electronic recording mechanisms.

scholarly journals Promoting Evidence-Based Practices for Breast Cancer Care Through Web-Based Collaborative Learning

2020 ◽  
Vol 6 (Supplement_1) ◽  
pp. 54-54
Author(s):  
Mishka K. Cira ◽  
Allison Dvaladze ◽  
Robel Tesfay ◽  
Jo Anne Zujewski ◽  
Kalina Duncan
Keyword(s):  
Breast Cancer ◽  
Collaborative Learning ◽  
Cancer Control ◽  
Project Teams ◽  
Global Network ◽  
Evidence Based ◽  
Web Based ◽  
Control Programs ◽  
End Point ◽  
Breast Cancer Control

PURPOSE The objective of the Project ECHO (Extension for Community Healthcare Outcomes) for Knowledge Summaries for Comprehensive Breast Cancer Control (KSBC) was to strengthen the capacity to plan and implement evidence-based, resource-appropriate breast cancer control programs using virtual case-based learning within a global network of experts and peers. METHODS The KSBC ECHO was a collaboration between the US National Cancer Institute Center for Global Health, Women’s Empowerment Cancer Advocacy Network, and Breast Health Global Initiative in alignment with the Breast Cancer Initiative 2.5 campaign to reduce disparities in breast cancer outcomes. Using the ECHO model, we developed a 6-month Web-based program to support the development of locally relevant, resource-appropriate cancer control programs through mentorship and use of KSBCs. The course was advertised via existing networks, conferences, and social media. Breast cancer control project teams from around the world applied and were accepted to participate in the KSBC ECHO. Fourteen biweekly ECHO sessions were held via Zoom and included case presentations, didactic presentations, and discussion. Projects spanned the care continuum and sessions addressed preplanning, assessing need/barriers, setting objectives/priorities, and implementing/evaluating. Baseline and end point surveys were used to evaluate the ECHO program. Participants identified a mentor, completed worksheets, and presented on the project status. RESULTS Fifteen project teams from 11 countries—64 participants: advocates, clinicians, policymakers, and researchers—were enrolled. Twenty-eight participants (57%) completed the baseline and end point surveys. Analysis of the data using a paired t-test indicates that the knowledge increase was statistically significant: The average knowledge gain was 0.76 ± 0.89 (95% CI, 0.44 to 1.08; P < .0001). Additional feedback on the Web-based collaborative learning model will be presented. CONCLUSION The ECHO model encouraged interaction between policymakers, clinicians, advocates, and technical experts while using evidence-based tools to develop locally relevant, resource-appropriate implementation strategies and policy recommendations.

Challenges in breast cancer control in Malaysia

2021 ◽  
Vol 17 ◽  
Author(s):  
Noor Fatmawati Mokhtar ◽  
Hemaniswarri Dewi Dewadas ◽  
Juhara Haron ◽  
Maya Mazwin Yahya ◽  
Bachok Norsa’adah ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Control ◽  
Late Presentation ◽  
Control Programme ◽  
Evidence Based ◽  
South East Asia ◽  
Poor Survival ◽  
Local Data ◽  
Cancer Trajectory ◽  
Breast Cancer Control

: High proportion of late presentation and poor survival of women with breast cancer in Malaysia does not reflect the country’s status as the third richest country in South East Asia. Herein, we examined, and collated research articles related to breast cancer trajectory i.e., primary, secondary, and tertiary prevention in Malaysia to understand, appreciate and recognize the achievements but also gaps which undermines Malaysia’s response in handling the disease. In summary, the integral task for Malaysia is to strategically align research to improve local data (research) on the extent of the country’s breast cancer problem thus from there, effective, comprehensive, evidence-based cancer control programme founded on resource level can be generated.

scholarly journals Phased Implementation Model of Resource-Stratified Guidelines for Breast Cancer Control

2017 ◽  
Vol 3 (2_suppl) ◽  
pp. 17s-17s ◽  
Author(s):  
Allison Dvaladze ◽  
Catherine Duggan ◽  
Julie R. Gralow ◽  
Benjamin O. Anderson
Keyword(s):  
Breast Cancer ◽  
Scale Up ◽  
Cancer Control ◽  
Breast Disease ◽  
Evidence Based ◽  
Breast Health ◽  
Implementation Model ◽  
Palpable Breast ◽  
Breast Cancer Control ◽  
Advisory Role

Abstract 59 Background: Review of breast cancer control efforts in low- and middle-income countries (LMICs) has identified the need for a model to bridge the gap between evidence-based planning and implementation or scale-up of breast cancer diagnosis and treatment programs. We undertook this work to develop an evidence-based framework to guide systematic implementation of resource-stratified, effective, and sustainable systems to improve breast health care delivery in LMICs. Methods: On the basis of survey data and site visits, Breast Cancer Initiative 2.5 (BCI2.5) partners developed a phased implementation model for breast cancer management in LMICs. The model outlines an adaptable framework for step-wise implementation of health system requirements across the continuum of care, with successful and systematic management of clinically detectable (palpable) breast disease being a prerequisite to population-based screening. Prerequisites: Standardized protocols, guidelines, and trained health care workforce. Phase 1: Systematic triage and diagnosis of palpable breast disease; phase 2: adapted stage-appropriate treatment planning; phase 3: scaling-up of clinical breast exam to promote downstaging of clinically detectable disease; and phase 4: upgrading of image-based diagnostic systems and management of nonpalpable disease. Once these systems are in place, mammographic screening can be initiated. Results: Successful implementation of the Breast Health Global Initiative resource-stratified guidelines in northern Peru from 2011 to 2016 followed this phased implementation strategy and demonstrated that this approach can help advance specific aspects of a comprehensive cancer control plan in a systematic fashion, surmounting what may seem to be overwhelming barriers to improving early diagnosis. Conclusion: By using this model, BCI2.5 partners, in collaboration with the Government of Tanzania, are developing recommendations to inform the design, implementation, and scale-up of a breast cancer early diagnosis and treatment platform that can be achieved if adequately resourced and implemented in a phased fashion. AUTHORS' DISCLOSURES OF POTENTIAL CONFLICTS OF INTEREST Allison Dvaladze Consulting or Advisory Role: Pfizer Travel, Accommodations, Expenses: Roche Catherine Duggan No relationship to disclose Julie R. Gralow Consulting or Advisory Role: Novartis, Genentech, Eli Lilly, Bayer, Pfizer Research Funding: Genentech (Inst), Novartis (Inst), Amgen (Inst) Benjamin O. Anderson Consulting or Advisory Role: Pfizer Research Funding: Pfizer, Roche

Impact of disruptions in breast cancer control due to the COVID-19 pandemic on breast cancer mortality in the United States: Estimates from collaborative simulation modeling.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 6562-6562
Author(s):  
Oguzhan Alagoz ◽  
Kathryn P. Lowry ◽  
Allison W. Kurian ◽  
Jeanne S. Mandelblatt ◽  
Mehmet Ali Ergun ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Mortality ◽  
Early Stage ◽  
Breast Cancer Mortality ◽  
Cancer Control ◽  
The United States ◽  
Sensitivity Analyses ◽  
The Impact ◽  
Excess Deaths ◽  
Breast Cancer Control

6562 Background: The COVID-19 pandemic has disrupted breast cancer control through short-term declines in screening, delays in diagnosis and reduced/delayed treatments. We projected the impact of COVID-19 on future breast cancer mortality.Methods: Three established Cancer Intervention and Surveillance Modeling Network (CISNET) models projected the impact of pandemic-related care disruptions on breast cancer mortality between 2020 and 2030 vs. pre-pandemic care patterns. Based on Breast Cancer Surveillance Consortium data, we modeled reductions in mammography screening utilization, delays in symptomatic cancer diagnosis, and reduced use of chemotherapy for women with early-stage disease for the first six months of the pandemic with return to pre-pandemic patterns after that time. Sensitivity analyses were performed to determine the effect of key model parameters, including the duration of the pandemic impact. Results: By 2030, the models project 1,297 (model range: 1,054-1,900) cumulative excess deaths related to reduced screening; 1,325 (range: 266-2,628) deaths from delayed diagnosis of symptomatic women, and 207 (range: 146-301) deaths from reduced chemotherapy use for early-stage cancer. Overall, the models predict 2,487 (range 1,713-4,875) excess deaths, representing a 0.56% (range: 0.36%-0.99%) cumulative increase over deaths that would be expected by 2030 in the absence of the pandemic’s disruptions. Sensitivity analyses indicated that the impact on mortality would approximately double if the disruptions lasted for a 12-month period. Conclusions: The impact of the initial pandemic-related disruptions in breast cancer care will have a small long-term cumulative impact on breast cancer mortality. The impact of the initial pandemic-related disruptions on breast cancer mortality will largely be mitigated by the rapid return to usual care. As the pandemic continues it will be important to monitor trends in care and reassess the mortality impact.[Table: see text]

scholarly journals Breast Cancer Initiative 2.5 (BCI2.5): A Global Campaign to Reduce Disparities in Breast Cancer Outcomes

2016 ◽  
Vol 2 (3_suppl) ◽  
pp. 21s-22s ◽  
Author(s):  
Allison Dvaladze ◽  
Catherine Duggan ◽  
Julie R. Gralow ◽  
Benjamin O. Anderson
Keyword(s):  
Breast Cancer ◽  
Health Care ◽  
Implementation Science ◽  
Technical Assistance ◽  
Evidence Based ◽  
Breast Health ◽  
Cancer Outcomes ◽  
Low Resource Settings ◽  
Low Resource ◽  
Breast Cancer Outcomes

Abstract 20 Aim: Breast Cancer Initiative 2.5 (BCI2.5) is a global campaign to reduce disparities in breast cancer outcomes for 2.5 million women by 2025. About BCI2.5: BCI2.5 represents a new commitment to unite the global breast cancer community behind a common goal to make breast health a global priority and reduce disparities in breast cancer outcomes worldwide. The initiative began as a call for action in 2014, supported by the American Cancer Society, Susan G. Komen and UICC. Since that initial pledge, BCI2.5 has been engaging partners around the world, assessing need, identifying priorities and defining a strategy to meet this goal. Its consensus-based approach empowers regional champions to bring about change with the aid of BCI2.5 analytic, assessment and planning tools, educational materials and implementation science research methodology. BCI2.5 delivers evidence-based technical expertise and a resource-stratified approach to improving breast health services and care at any resource level. The initiative is inclusive and encourages organizations, institutions and countries to connect and join the effort. Why BCI2.5: Breast cancer is the most prevalent cancer in women worldwide. Estimates suggest that 5.8 million women will die from breast cancer by 2025, with a disproportionate number of these deaths occurring in low-resource settings. Higher breast cancer case fatality rates in low-resource settings have been attributed to a lack of awareness regarding the benefits of early detection and treatment, late stage diagnosis and limited access to appropriate care. To reduce this global disparity in breast cancer outcomes for 2.5 million women by 2025, BCI2.5 is exploring innovative ways to implement affordable, appropriate, acceptable and feasible evidence-based strategies. A key element of this initiative is identifying, documenting and fostering dissemination of new and innovative approaches to the delivery of breast health care developed in low-resource settings. This demands a collaborative effort that draws on the collective expertise and resources of individuals and institutions engaged in breast cancer care. The BCI2.5 Strategy: The BCI2.5 strategy consists of the following: Outreach. BCI2.5 engages regional alliances, organizations, experts and advocates to assess specific needs and to determine how BCI2.5 technical expertise can be leveraged most effectively. Tools, innovation and information. Tools. BCI2.5 is developing situation analyses tools to aid countries in assessing need and identifying bottlenecks in breast health care delivery. BCI2.5 is also developing models to estimate the impact of providing early diagnosis and treatment interventions in different resource settings. These models will assist in determining the most effective and appropriate interventions given available resources. Innovation. BCI2.5 seeks to support innovative approaches to addressing breast health care in low-resource settings by linking partners and developing a library of case studies featuring innovative evidence-based approaches to breast health care in different resource settings and facilitating their dissemination. Information. BCI2.5 is building an online library featuring Knowledge Summaries, Case Studies and other educational resources. Global Breast Health Analytics Map (GloBAM). GloBAM is an interactive data visualization tool for analyzing the determinants of the global breast cancer burden. GloBAM provides a means for linking data on breast cancer incidence and mortality, health spending, cancer policies and practices, determinants of health and more by country. It is vital to mapping health system resource levels, identifying gaps in breast health care and shaping resource-appropriate solutions. Situation Analyses. BCI2.5 is supporting baseline assessments and situation analyses utilizing the BCI2.5 self-assessment tools, Global Breast Health Analytics Map (GloBAM), stakeholder mapping, focus groups and other methods as appropriate. Breast Cancer Action Plans (BCAP). Through a collaborative process BCI2.5 supports partners and multidisciplinary teams in developing resource-appropriate action plans to assist countries in the decision-making process and outline next steps in implementing improvements in breast health care. BCI2.5 Master Courses. BCI2.5 is developing modular online curriculum units using the above mentioned tools and resources for advocates, policy makers and clinicians. Technical Assistance and Implementation Research. BCI2.5 works collaboratively with partner organizations and countries to facilitate implementation of evidence-based breast health care programs for scale-up, and develop metrics and implementation science methodology to evaluate plan implementation, and to assess systems-based outcomes. BCI2.5 Master Courses. BCI2.5 is developing modular curriculum units using the above mentioned tools and resources. Courses will target advocates, policy makers and clinicians. Materials will be available online via the BCI2.5 website. Technical Assistance and Implementation Research. BCI2.5 works collaboratively with partner organizations and countries to facilitate implementation of evidence-based breast health care programs for scale-up, and develop metrics and implementation science methodology to evaluate, to plan implementation, and to assess systems-based outcomes. AUTHORS' DISCLOSURES OF POTENTIAL CONFLICTS OF INTEREST: Allison Dvaladze Travel, Accommodations, Expenses: Roche Catherine Duggan No relationship to disclose Julie R. Gralow Consulting or Advisory Role: Novartis, Roche, Pfizer Benjamin O. Anderson Research Funding: Pfizer, Roche

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