Bioprospecting of Antimicrobial Carica papaya Leaf Extract for Finishing of Fabrics in Health Care Industries

Papaya leaves has been shown to have efficacy as an analgesic. Analgesic effect caused by the flavonoids in leaves of papaya. To enhance the analgesic effi cacy papaya into dosage formulatio of nanoparticles. The purpose of this research was to create and characterized nanoparticles from ethanol extract of papaya leaves then tested for effectiveness as an analgesic. This study used polymer chitosan and NaTPP to created nanoparticles through ionic gelation method and analgesic activity tested using writhing test method and statistical tested. Optimal formula of nanoparticles were produced at concentration of 0.2% chitosan, Na-TPP extract 0.1% and 4% with a ratio of 6: 1: 1. The nanoparticles was formed a size of 255.4 nm with polidispers index of 0.7, the zeta potential of + 11,1mV, the adsorption effi ciency by 87% and rounded morphology (spherical). Analgesic effectiveness tested by comparison between the groups ethanol extract of papaya and the groups nanoparticles of chitosan-ethanol extract papaya statistically using the T-test Independent. The results of this research indicate that there are statistically signifi cant differences (p <0.05). This results shows that the preparation nanoparticles of chitosan-ethanol extract papaya is more effective as an analgesic than the ethanol extract of papaya leaves.

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Effect of Carica papaya (Linn) aqueous leaf extract on pharmacokinetic profile of ciprofloxacin in rabbits

Tropical Journal of Pharmaceutical Research ◽

10.4314/tjpr.v16i1.16 ◽

2017 ◽

Vol 16 (1) ◽

pp. 127 ◽

Cited By ~ 2

Author(s):

Grace E. Ukpo ◽

Mbang A. Owolabi ◽

Ngozi O.A. Imaga ◽

Oluwafunke O. Oribayo ◽

Akpobomen J. Ejiroghene

Keyword(s):

Leaf Extract ◽

Carica Papaya ◽

Pharmacokinetic Profile ◽

Aqueous Leaf Extract

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EFFECT OF FLOUR AND PAPAYA LEAF EXTRACT (Carica papaya L.) ADDITION TO FEED ON GAS PRODUCTION, DIGESTIBILITY AND ENERGY VALUES IN VITRO

TERNAK TROPIKA Journal of Tropical Animal Production ◽

10.21776/ub.jtapro.2016.017.02.10 ◽

2016 ◽

Vol 17 (2) ◽

pp. 74-85

Author(s):

Miftahul Khoiriyah ◽

Siti Chuzaemi ◽

Herni Sudarwati

Keyword(s):

Leaf Extract ◽

Carica Papaya ◽

Gas Production

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The plausible mechanisms of action of Carica papaya on Dengue infection: A comprehensive review

Progress in Drug Discovery & Biomedical Science ◽

10.36877/pddbs.a0000097 ◽

2020 ◽

Vol 3 (1) ◽

Author(s):

Zhui Ken Bok ◽

Manisha Balakrishnan ◽

Yong Xin Jong ◽

Yew Rong Kong ◽

Kooi Yeong Khaw ◽

...

Keyword(s):

At Risk ◽

Clinical Evaluation ◽

Leaf Extract ◽

Carica Papaya ◽

Dengue Infection ◽

Mechanisms Of Action ◽

Treatment Modalities ◽

Potential Treatment ◽

Comprehensive Review ◽

Leaf Juice

Dengue is a serious health endemic with a prediction that 2.5 billion are at risk of acquiring dengue infection and 50 million are infected yearly. Over the years, tremendous effort has been done to develop potential treatment for dengue infection. However, to no avail, most of the treatment modalities have failed in clinical evaluation and trials. With the lack of treatment for dengue infection, home remedies have been widely used as a belief to relieve the symptoms, one of them is the use of papaya leaf juice. This review provides a recent evidences and research that have been attempted to unravel the mechanism of actions of papaya leaf extract to treat dengue infection. Up to date, there are three main mechanisms that have been proposed, which are the anti-thrombocytopenic, immunomodulatory and anti-viral effect of papaya leaf juice extract.

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