Cellular Mechanisms behind Particulate Matter Air Pollution–Related Health Effects

Air Pollution ◽  
2010 ◽  
pp. 249-274 ◽  
Author(s):  
Ernesto Alfaro-Moreno ◽  
Claudia Garc√≠a-Cuellar ◽  
Andrea De-Vizcaya-Ruiz ◽  
Leonora Rojas-Bracho ◽  
Alvaro Osornio-Vargas
Author(s):  
Francis Olawale Abulude

Particulate matter (PM) is one of the problems faced in environmental science. It has health effects on man and animals in both developed and developing countries. Research and efforts have been on it several years back. Policy statements and efforts have been published. This review paper is an added information on air pollution. In it, efforts were made in discussing these: classification, effects, methodology, case studies and source apportionment. It is hoped that this paper would contribute to existing knowledge on PM.


2018 ◽  
Vol 10 (30) ◽  
pp. 3745-3753 ◽  
Author(s):  
Alexandra Beal ◽  
Fernanda Garcia de Almeida ◽  
Camila A. B. Moreira ◽  
Isis M. Santos ◽  
Suzana M. M. Curti ◽  
...  

Air pollution by lead, even in small concentrations, can cause serious health effects.


2020 ◽  
Author(s):  
Stephanie Koller ◽  
Christa Meisinger ◽  
Markus Wehler ◽  
Elke Hertig

<p>For a long time it has been known that exceptionally strong and long-lasting heat waves have negative health effects on the population, which is expressed in an intensification of existing diseases and over-mortality of certain risk groups (Kampa, Castanas 2008). Often associated with heat are stagnant airflow conditions that cause a large increase in the concentration of certain air substances (Ebi, McGregor 2008). Many of these air substances have a strong adverse effect on the human organism (Kampa, Castanas 2008).</p><p>The aim of the project is to investigate the actual hazard potential of health-relevant air pollution- and climatological variables by quantifying the effects on human health of increased exposure to air constituents and temperature extremes. Different multivariate statistical methods such as correlation analysis, regression models and random forests, extreme value analysis and individual case studies are used.</p><p>As a medical data basis for this purpose, the emergency department data of the University Hospital Augsburg are regarded. In addition to the diagnosis, supplementary information such as age, gender, place of residence and pre-existing conditions of the patients are used. Among the air constituents, the focus is on ozone, nitrogen dioxide and particulate matter. In the meteorological part, the focus is primarily on temperature, which is not only a direct burden but, as in the case of ozone, also has a decisive influence on the formation of ozone molecules. However, a large number of other meteorological parameters such as precipitation, relative humidity and wind speed as well as the synoptic situation also play a major role in the formation, decomposition process and the distribution of pollutants (Ebi, McGregor 2008).</p><p>The first major question to answer is whether air-pollution and meteorological stress situations are visible in the emergency department data. Further in-depth questions are which factors have the greatest negative impact, what is the most common environment-related disease, which weather conditions carry a higher than average risk and what are the health risks of climate change.</p><p>Ideally, the analysis may also provide a short-term forecast from which to derive whether or not there will be an above or below average number of visits to the emergency department.</p><p>The project is funded by the German Federal Foundation for Environment (DBU) and the German Research Foundation (DFG) - project number 408057478.</p><p>Literature</p><p>Ebi K., McGregor G. (2008): Climate Change, Tropospheric Ozone and Particulate Matter, and Health Impacts. doi: 10.1289/ehp.11463</p><p>Kampa M., Castanas E. (2008): Human health effects of air pollution. In: Environmental Pollution 151(2): 362-367. doi: 10.1016/j.envpol.2007.06.012</p>


2007 ◽  
Vol 333 (4) ◽  
pp. 235-243 ◽  
Author(s):  
Tze-Ming Chen ◽  
Ware G. Kuschner ◽  
Janaki Gokhale ◽  
Scott Shofer

Author(s):  
Nadhirah Nordin ◽  
M. Rafee Majid ◽  
Ho Chin Siong ◽  
Gakuji Kurata

Malaysia is currently experiencing issues of local as well as transboundary air pollution. The issues are especially felt in areas that record high economic growth and rapid urbanization such as Iskandar Malaysia, a fast evolving economic-growth corridor in Southeast Asia. This has led to increased rate of particulate matter emissions, which further led to increase in the rate of respiratory-related health incidences. Many epidemiological studies have proven that particulate matters in the ambient air are associated with adverse health effects. This will affect the existing and future economy of Iskandar Malaysia, where the exposed population may lose their workdays and face increased medical spending. This study focuses on quantifying health and economic benefits from the reduction of particulate matter with a size of 10 micrometers or less in diameter (PM10) using the Environmental Benefits Mapping and Analysis Program (BenMAP) by US EPA. Health impact functions are used to quantify the relationship between a change in PM10 level and number of related health effects among the exposed population. The samples for this research include a continuous monitoring data on the 2014 monthly average of daily PM10, the 2014 population projection of Malaysian Census Data and the PM10 related health cases for 2014 which are focused in the Iskandar Malaysia region. PM10 data are collected from monitoring stations operated by the Department of Environment (DOE). Respiratory related cases such as Upper Respiratory Tract Infection, which is categorized as J10 in International Classification of Diseases, are collected from selected clinics within the study area. The final outcome of the modeling exercise compares the co-benefits of air pollution reduction between the baseline scenario and the control scenario for PM10 level in Iskandar Malaysia. The results of this study are useful in optimizing and improving the existing policies and strategies for controlling air pollution and PM10 emission in Iskandar Malaysia.


Author(s):  
Tanwi Trushna ◽  
Amit K. Tripathi ◽  
Sindhuprava Rana ◽  
Rajnarayan R. Tiwari

: Air pollution, especially particulate matter pollution adversely affects human health. A growing pool of evidence has emerged which underscores the potential of individual-level nutritional interventions in attenuating the adverse health impact of exposure to PM2.5. Although controlling emission and reducing the overall levels of air pollution remains the ultimate objective globally, the sustainable achievement of such a target and thus consequent protection of human health will require a substantial amount of time and concerted efforts worldwide. In the meantime, smaller-scale individual-level interventions that can counter the inflammatory or oxidative stress effects triggered by exposure to particulate matter may be utilized to ameliorate the health effects of PM2.5 pollution. One such intervention is incorporation of nutraceuticals in the diet. Here, we present a review of the evidence generated from various in vitro, in vivo and human studies regarding the effects of different anti-inflammatory and antioxidant nutraceuticals in ameliorating the health effects of particulate matter air pollution. The studies discussed in this review suggest that these nutraceuticals when consumed as a part of the diet, or as additional supplementation, can potentially negate the cellular level adverse effects of exposure to particulate pollution. The potential benefits of adopting a non-pharmacological diet-based approach to air pollution-induced disease management have also been discussed. We argue that before a nutraceuticals-based approach can be used for widespread public adoption, further research, especially human clinical trials, is essential to confirm the beneficial action of relevant nutraceuticals and to explore the safe limits of human supplementation and the risk of side effects. Future research should focus on systematically translating bench-based knowledge regarding nutraceuticals gained from in-vitro and in-vivo studies into clinically usable nutritional guidelines.


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