scholarly journals Polyunsaturated fatty acid concentrations in human hindmilk are stable throughout 12-months of lactation and provide a sustained intake to the infant during exclusive breastfeeding: an Italian study

2000 ◽  
Vol 84 (1) ◽  
pp. 103-109 ◽  
Author(s):  
Franca Marangoni ◽  
Carlo Agostoni ◽  
Anna M. Lammard ◽  
Marcello Giovannini ◽  
Claudio Galli ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Human Milk ◽  
Acid Composition ◽  
Saturated Fatty Acids ◽  
Total Fat ◽  
Extended Lactation ◽  
Long Chain

While a wealth of data on the fatty acid composition of mature human milk has been published, limited information is available on the quantities of individual fatty acids supplied to the suckling infant with maternal milk, through the whole first year of life. Our aim was to qualitatively and quantitatively evaluate the fatty acid composition of human milk from Italian mothers, throughout extended lactation with particular emphasis on the long-chain polyunsaturated fatty acids. We have thus measured the total fat content and the concentrations of major fatty acids by quantitative GLC in pooled breast hindmilk collected from all feedings over 24 h at colostrum, 1, 3, 6, 9 and 12 months in ten mothers recruited after delivery of full-term infants. Total saturated fatty acids progressively increase and total monounsaturated progressively decrease as percentage levels, while among long-chain polyunsaturated fatty acids, percentages of arachidonic acid and docosahexaenoic acid decrease from colostrum up to the third month. Hindmilk total lipids (mg/dl) rise more than twofold up to 3 months, and then remain stable. The amounts (mg/dl) of linoleic acid and α-linolenic acid progressively increase, following the trend of total fat, while arachidonic and docosahexaenoic concentrations (mg/dl) remain stable throughout the whole nursing period. Assessment of the intakes per kg body weight shows different trends for the individual major long-chain polyunsaturated fatty acids supplied to the infant from hindmilk during exclusive breast-feeding (3 months). This information may be useful for the evaluation of infant intakes during extended lactation.

Changes in fatty acid composition of human milk over lactation stages and relationship with dietary intake in Chinese women

2016 ◽  
Vol 7 (7) ◽  
pp. 3154-3162 ◽  
Author(s):  
Jiajing Jiang ◽  
Kejian Wu ◽  
Zuxun Yu ◽  
Yiping Ren ◽  
Yiming Zhao ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Human Milk ◽  
Dietary Intake ◽  
Acid Composition ◽  
Chinese Women ◽  
Long Chain ◽  
Nutrition Source

Human milk is considered as an optimal nutrition source for neonates, and long chain polyunsaturated fatty acids have a key function in neurodevelopment for infants.

scholarly journals Influence of savory essential oil on the fatty acids composition in the brain and liver with age increasing of akr line mice

2011 ◽  
Vol 57 (6) ◽  
pp. 604-614 ◽  
Author(s):  
T.A. Misharina ◽  
E.B. Burlakova ◽  
L.D. Fatkullina ◽  
M.B. Terenina ◽  
N.I. Krikunova ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Essential Oil ◽  
Polyunsaturated Fatty Acids ◽  
Acid Composition ◽  
Saturated Fatty Acids ◽  
Monounsaturated Fatty Acids ◽  
Age Related

Age-related alterations of fatty acid composition in liver and brain of AKR mice was investigated. The effect of savory essential oil (Satureja hortensis L.), added with drinking water on fatty acid composition in these organs and the processes of lipid peroxidation in erythrocytes were estimated. It was found that during aging the percentage of saturated fatty acids and polyunsaturated fatty acids decreased while monounsaturated fatty acids increased. The development of leukemia was accompanied by the increase of saturated and polyunsaturated fatty acids percentage and a decrease of monounsaturated fatty acids amount. In the liver aging caused the increase in the percentage of saturated fatty acids, the decrease of monounsaturated fatty acids, while the amount of polyunsaturated fatty acids was not changed. Leukemia (after 8 month) was accompanied by the increase of percentage of monounsaturated fatty acids and the decrease in the amount of oleinic and docosohexaenic acids. The intake of savory essential oil was accompanied by intensification of polyunsaturated fatty acids synthesis in mice liver and reduction of lipid peroxidation products content.

Fatty acid composition and quality of muscle from steers fed ruminally protected lipid

2002 ◽  
Vol 2002 ◽  
pp. 178-178
Author(s):  
M. Enser ◽  
N. Scollan ◽  
S. Gulati ◽  
G. Nute ◽  
K. Hallett ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Acid Composition ◽  
Saturated Fatty Acids ◽  
Protein Matrix ◽  
The Uk ◽  
Lipid Supplement

Recommendations to improve the UK diet suggest an increase in the ratio of polyunsaturated to saturated fatty acids (P:S ratio) and a higher consumption of n-3 polyunsaturated fatty acids (PUFA). Ruminant meats have a poor P:S ratio, approximately 0.1 compared to the recommendation of 0.4-1.0 for the whole diet. However, the ratio of C18:2 n-6/C18:3 n-3 (the n-6:n-3) is well within the recommended value of <4.0 at approximately 2 and ruminant muscle also supplies longer-chain n-3 PUFA. By feeding lipid in a formaldehyde cross-linked protein matrix, rumen biohydrogenation can be avoided and the tissue PUFA level increased but with potential effects on oxidative shelf-life, colour and flavour of the meat. This trial investigated the fatty acid composition and quality of meat produced by feeding a protected lipid supplement (PLS).

scholarly journals Omega-3 polyunsaturated fatty acids increase purine but not pyrimidine transport in L1210 leukaemia cells

1996 ◽  
Vol 315 (1) ◽  
pp. 329-333 ◽  
Author(s):  
Danielle MARTIN ◽  
Kelly A. MECKLING-GILL
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Acid Composition ◽  
Fold Increase ◽  
Omega 3 ◽  
Membrane Phospholipids ◽  
Epa And Dha ◽  
Long Chain

Here we show that in vitro supplementation of L1210 murine lymphoblastic leukaemia cells with n-3 polyunsaturated fatty acids results in considerable changes in the fatty acid composition of membrane phospholipids. Incubations for 48 h with 30 μM eicosapentaenoic acid (20:5, n-3; EPA) or docosahexaenoic acid (22:6, n-3; DHA) results primarily in substitution of long-chain n-6 fatty acids with long-chain n-3 fatty acids. This results in a decrease in the n-6/n-3 ratio from 6.9 in unsupplemented cultures to 1.2 or 1.6 for EPA and DHA supplemented cultures, respectively. Coincident with these changes in membrane fatty acid composition, we observed a 5-fold increase in the rate of adenosine (5 μM) uptake via the nitrobenzylthioinosine (NBMPR)-sensitive nucleoside transporter in EPA- and DHA- supplemented L1210 cells, relative to unsupplemented cells. This seemed to result from a decrease in the Km for adenosine from 12.5 μM in unsupplemented cultures to 5.1 μM in DHA-treated cultures. Guanosine (50 μM) transport was similarly affected by DHA with a 3.5-fold increase in the initial rate of uptake. In contrast, pyrimidine transport, as measured by uptake of thymidine and cytidine, was not similarly affected, suggesting that substrate recognition had been altered by fatty acid supplementation. Studies using [3H]NBMPR showed that there was no effect of EPA or DHA on either the number of NBMPR-binding sites or the affinity of these sites for NBMPR. This observation suggests that the increases in adenosine and guanosine transport were not due to increases in the number of transporter sites but rather that EPA and DHA directly or indirectly modulate transporter function.

scholarly journals The Polyunsaturated Fatty Acid Profile of Extracellular Vesicles in Human Milk

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1037-1037
Author(s):  
John Miklavcic ◽  
Diana Bickmore ◽  
Laura Glynn
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Human Milk ◽  
Acid Composition ◽  
Extracellular Vesicles ◽  
Mammalian Cells ◽  
Omega 3 ◽  
Whole Milk

Abstract Objectives Mammalian cells produce extracellular vesicles that function in intercellular communication. There is very little known about the structure of extracellular vesicles that are present in human milk. This research aimed to characterize the fatty acid composition of extracellular vesicles in human milk relative to the whole milk. Methods Mothers (n = 35) provided milk two weeks postpartum and the samples were frozen. Samples were thawed and de-fatted before extracellular vesicles were isolated using a precipitation reagent. The whole milk and corresponding samples of extracellular vesicles were analyzed for total fatty acid composition by liquid chromatography-coupled mass spectrometry. Results Docosahexaenoic (22:6n-3) acid (r,2 = 0.54; P &lt; 0.001) and eicosapentaenoic (20:5n-3) acid (r,2 = 0.62; P &lt; 0.001) content in extracellular vesicles from milk and in the whole milk were highly correlated. Other individual fatty acids (16:0, 18:0, 18:1, 18:2n-6, 18:3n-3, 20:4n-6) and total saturated, unsaturated, and polyunsaturated fatty acids were not significantly correlated in extracellular vesicles from milk and in the whole milk. The content of docosahexaenoic acid and eicosapentaenoic acid were enriched 1.5-fold in the whole milk relative to extracellular vesicles from milk. Linoleic (18:2n-6) acid and alpha-linolenic (18:3n-3) acid were enriched 3- and 2-fold respectively in extracellular vesicles from milk relative to the whole milk. Conclusions Extracellular vesicles in milk are enriched in essential fatty acid precursors (18:2n-6, 18:3n-3) and the whole milk is enriched in long-chain omega-3 products (22:6n-3, 20:5n-3). Polyunsaturated fatty acids are partitioned in human milk extracellular vesicles in a discriminate manner. Funding Sources The research was supported by the NIH and University institutional funds.

Fatty Acid Composition of Turkey Meat Sucuk (Soudjuck), Salami, and Sausages

2008 ◽  
Vol 4 (2) ◽  
Author(s):  
Semih Otles ◽  
Ozlem Cagindi
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Acid Composition ◽  
Unsaturated Fatty Acids ◽  
Methyl Esters ◽  
Saturated Fatty Acids ◽  
Turkey Meat ◽  
Oleic And Linoleic Acids

In this paper, the fatty acid composition of turkey meat sucuk (soudjuck), salami, and sausages were determined and compared with each other. The fatty acids methyl esters of each product were identified by capillary gas chromatography. Most of the fatty acids in sucuk (soudjuck) samples were monosaturated; however in salami and sausages samples most of were mono and di-unsaturated. Saturated fatty acids in sucuk (soudjuck) samples followed, having the palmitic and stearic acids as their major components and had a range of 229.7-385.2 g kg-1 and 87.6-215.9 g kg-1. In salami and sausages samples, unsaturated fatty acids, the oleic and linoleic acids were the major components and had a range of 170.0-542.0 g kg-1 and 151.5-353.0 g kg-1. PUFA (polyunsaturated fatty acids) were found for sausages in the highest amount with linoleic acids concentration. Turkey meat salami and sausages presented a higher content of unsaturated and polyunsaturated fatty acids than turkey meat sucuk (soudjuck).

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