scholarly journals GLP-1 Analog Modulates Appetite, Taste Preference, Gut Hormones, and Regional Body Fat Stores in Adults with Obesity

2019 ◽  
Vol 105 (5) ◽  
pp. 1552-1563 ◽  
Author(s):  
Hoda Kadouh ◽  
Victor Chedid ◽  
Houssam Halawi ◽  
Duane D Burton ◽  
Matthew M Clark ◽  
...  
Keyword(s):  
Lean Body Mass ◽  
Body Mass ◽  
Body Fat ◽  
Peptide Yy ◽  
Gut Hormones ◽  
Taste Preference ◽  
Gastrointestinal Hormone ◽  
Once Daily ◽  
Fat Stores ◽  
Regional Body Fat

Abstract Purpose Obesity is associated with alterations in appetite, gastrointestinal hormone levels and excessive fat mass. We previously published a double-blind, placebo-controlled, randomized, 16-week trial on effects of once-daily glucagon-like peptide-1 (GLP-1) analog, liraglutide on weight, satiation, and gastric functions in obese volunteers. The aim of this substudy is to compare to placebo the effects of liraglutide on appetite, taste preference, regional body fat stores, and anthropometric measurements. Methods Forty obese adults received standard instruction for weight management, monthly behavioral intervention utilizing motivational interviews, and 16-week treatment of once-daily liraglutide (escalated to 3 mg SQ daily). At baseline and 16 weeks, the following were measured: appetite and taste preferences rated every 30 min for 5 h after ingesting 300 mL Ensure®; maximal tolerated volume (MTV) with a nutrient drink test; fasting and postprandial bioactive GLP-1 (7–36) and peptide YY (PYY) levels; total and regional body fat with dual-energy X-ray absorptiometry, and waist and hip circumference. Results Thirty-five participants (17 liraglutide; 18 placebo) completed the trial. Compared to placebo group, liraglutide group had significant reductions in MTV; prospective food consumption score; desire to eat something sweet, salty, savory or fatty; and an increase in perceived fullness. Postprandial plasma levels of GLP-1 decreased and PYY levels increased with liraglutide relative to baseline. Significant reductions in total body, trunk, and upper and lower body fat without reduction in lean body mass were observed. Conclusion Liraglutide 3 mg SQ modulates appetite, taste preference, gut hormones, and regional body fat stores in adults with obesity without reduction in lean body mass.

scholarly journals Relationship between body fat, lean body mass and disease severity in AECOPD patients

2021 ◽  
Author(s):  
Yiben Huang ◽  
Jiedong Ma ◽  
Xueting Hu ◽  
Jianing Wang ◽  
Xiaqi Miao ◽  
...  
Keyword(s):  
Disease Severity ◽  
Lean Body Mass ◽  
Body Mass ◽  
Body Fat

Comparison of the Effect of Soy protein and Whey protein on Body Composition: A Meta-Analysis of Randomized Clinical Trials

2021 ◽  
pp. 1-27
Author(s):  
Masoome Piri Damaghi ◽  
Atieh Mirzababaei ◽  
Sajjad Moradi ◽  
Elnaz Daneshzad ◽  
Atefeh Tavakoli ◽  
...  
Keyword(s):  
Body Composition ◽  
Whey Protein ◽  
Lean Body Mass ◽  
Body Mass ◽  
Body Fat ◽  
Fat Mass ◽  
Soy Protein ◽  
Protein Supplementation ◽  
Body Fat Percentage ◽  
Fat Percentage

Abstract Background: Essential amino acids (EAAs) promote the process of regulating muscle synthesis. Thus, whey protein that contains higher amounts of EAA can have a considerable effect on modifying muscle synthesis. However, there is insufficient evidence regarding the effect of soy and whey protein supplementation on body composition. Thus, we sought to perform a meta-analysis of published Randomized Clinical Trials that examined the effect of whey protein supplementation and soy protein supplementation on body composition (lean body mass, fat mass, body mass and body fat percentage) in adults. Methods: We searched PubMed, Scopus, and Google Scholar, up to August 2020, for all relevant published articles assessing soy protein supplementation and whey protein supplementation on body composition parameters. We included all Randomized Clinical Trials that investigated the effect of whey protein supplementation and soy protein supplementation on body composition in adults. Pooled means and standard deviations (SD) were calculated using random-effects models. Subgroup analysis was applied to discern possible sources of heterogeneity. Results: After excluding non-relevant articles, 10 studies, with 596 participants, remained in this study. We found a significant increase in lean body mass after whey protein supplementation weighted mean difference (WMD: 0.91; 95% CI: 0.15, 1.67. P= 0.019). Subgroup analysis, for whey protein, indicated that there was a significant increase in lean body mass in individuals concomitant to exercise (WMD: 1.24; 95% CI: 0.47, 2.00; P= 0.001). There was a significant increase in lean body mass in individuals who received 12 or less weeks of whey protein (WMD: 1.91; 95% CI: 1.18, 2.63; P<0.0001). We observed no significant change between whey protein supplementation and body mass, fat mass, and body fat percentage. We found no significant change between soy protein supplementation and lean body mass, body mass, fat mass, and body fat percentage. Subgroup analysis for soy protein indicated there was a significant increase in lean body mass in individuals who supplemented for 12 or less weeks with soy protein (WMD: 1.48; 95% CI: 1.07, 1.89; P< 0.0001). Conclusion: Whey protein supplementation significantly improved body composition via increases in lean body mass, without influencing fat mass, body mass, and body fat percentage.

Biathlon Performance: Heart Rate, Hit Rate, Speed and Physiological Variables

2021 ◽  
Vol 15 (10) ◽  
pp. 3245-3249
Author(s):  
Gökhan Atasever ◽  
Fatih Kiyici ◽  
Deniz Bedir ◽  
Fatih Ağduman
Keyword(s):  
Heart Rate ◽  
Lean Body Mass ◽  
Body Mass ◽  
Body Fat ◽  
Maximum Speed ◽  
Fat Percentage ◽  
Physiological Variables ◽  
Cross Country Skiing ◽  
Cross Country ◽  
Short Time

Aim: Biathlon is a sport that combines cross-country skiing and rifle shooting. The athlete is fast in the cross-country skiing section, in the gun shooting section, the heart rate should be low. This study aims to determine the hitting rate of the shots made with different training loads on low altitude in elite biathletes in terms of maximum speed and physiological variables. Methods: To evaluate shooting performances first with the resting pulse and then after 2.5 km skiing respectively with 50%, 70% and 100% pulse rate which is separately calculated for each athlete according to karvonen formula. Results: Our findings show that while there was negative relation between maximum speed and body fat there was a positive relation with lean body mass. It has been determined that low body fat percentage and high lean body mass are effective at the athletes’ maximum speed and the pulse level with the highest target shooting accuracy rate was at rest and 70% in the second level. Conclusion: Since the pulse of the athlete who comes to the shooting area cannot be reduced to a resting level in a short time, focusing the 70% pulse zone may be beneficial in terms of shooting accuracy and acceleration after the shot. The lowest results in target shooting accuracy were seen at 50% and 100% loads. Keywords: Athletes, performance, heart, rate, lean body mass.

scholarly journals Lean Body Mass and Body Fat Distribution in Participants With Chronic Low Back Pain

2000 ◽  
Vol 160 (21) ◽  
pp. 3265 ◽  
Author(s):  
Yoshitaka Toda ◽  
Neil Segal ◽  
Tamami Toda ◽  
Tadanobu Morimoto ◽  
Ryokei Ogawa
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Lean Body Mass ◽  
Body Mass ◽  
Body Fat ◽  
Chronic Low Back Pain ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Low Back

scholarly journals Cardiorespiratory Fitness in University Level Volleyball Players and its Correlation with Body Fat

2020 ◽  
Vol 27 (3) ◽  
pp. 15-19
Author(s):  
Archana Khanna ◽  
Ankita Singh ◽  
Bhanu Pratap Singh ◽  
Faiz Khan
Keyword(s):  
Lean Body Mass ◽  
Body Mass ◽  
Cardiorespiratory Fitness ◽  
Body Fat ◽  
Vigorous Physical Activity ◽  
Step Test ◽  
Male And Female ◽  
Percentage Body Fat ◽  
Volleyball Players ◽  
University Level

Abstract Introduction. The present study was aimed to compare the cardiorespiratory fitness levels (VO2max) between university level male and female volleyball players and to find its correlation with percentage body fat. Material and Methods. In the present cross-sectional study, male and female volleyball players (n = 15 each) aged 18-25 years were randomly selected from Teerthanker Mahaveer University, Moradabad, India. An equal number of sedentary individuals were also selected who did not indulge in any vigorous physical activity or training. Body height, body weight, body mass index (BMI), % lean body mass of players and sedentary individuals were recorded using standard methods. Percentage body fat was calculated using the sum of four skinfolds and VO2max was recorded using Queen’s college step test. Data were analysed using SPSS software version 20.0. Unpaired t-test was used for comparison between players and sedentary individuals and two-way ANOVA was used to examine interaction of status (active players and sedentary individuals) and gender on VO2max. Results. Players had higher mean values for % lean body mass and VO2max. Statistically, highly significant differences (p < 0.05) were observed between male and female players for all variables except BMI. Players had better cardiorespiratory fitness (VO2max) as compared to their sedentary counterparts. Conclusions. Significant differences exist between players and sedentary individuals for percentage body fat and percentage lean body mass. Cardiorespiratory fitness of players is negatively correlated with percentage body fat. Players have higher VO2max as compared to their sedentary counterparts.

scholarly journals Body Morphometrics in NAFLD Population

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Harkeerat Dhami ◽  
Niharika Samala
Keyword(s):  
Lean Body Mass ◽  
Body Mass ◽  
Body Fat ◽  
Fat Mass ◽  
Percent Body Fat ◽  
Composition Analysis ◽  
Processed Meat ◽  
Body Fat Mass ◽  
High Sodium ◽  
Obstructive Sleep

Introduction: NAFLD is one of the common causes of liver disease in the US and is commonly associated with metabolic syndrome. Among obese, prevalence of NAFLD is 7090%. We wanted to determine body morphometrics in NAFLD. Methods: All individuals presenting to Indiana University Hospital with NAFLD were approached to participate in cross-sectional study. All participants were offered beverage, diet (REAP) questionnaires and body composition analysis using InBody 570, which utilizes bioelectrical impedance. Results: Of the 321 NAFLD individuals enrolled, 256 completed body morphometric analysis. Mean age of the cohort was 51.58 ± 13.54, 58% were female, 297 White and had a mean BMI of 35.92. 76% were obese, 48% had type 2 diabetes, 49.2% had hypertension, 38.6% had dyslipidemia, and 20.5% had obstructive sleep apnea. Despite having similar BMI, females had lower lean body mass (51.01 vs 70.51) and skeletal muscle mass (28.05 vs 39.70), higher body fat mass (46.71 vs 41.04) and percent body fat (46.59 vs. 35.7). Regular coffee consumers had lower BMI (35.3 vs 38, p=0.038), but lower body fat mass (39.9 vs 46.2, p=0.01), percent body fat (41.1 vs 44.4, p=0.05) and higher lean body mass % (58.8 vs 55.5, p=0.049). Processed meat consumption was associated with higher BMI (39 vs 35.3, P=0.01), percent body fat (45.5 vs 42, p=0.04), and lower lean body mass percentage (54.5 vs 58.2, P=0.04). Similar trends were seen with consumption of high sodium processed foods and watching television for ≥ 2 hours/day. Conclusion: Among individuals with NAFLD, we saw a higher female preponderance, who were found to have unfavorable body morphometrics despite similar BMI as males. Consumption of high sodium processed food and meat and excess screen time have unfavorable, while regular coffee drinkers have favorable body morphometrics, which offer modifiable measures for risk factors associated with NAFLD.

Exercise and body composition

1991 ◽  
Vol 70 (3) ◽  
pp. 994-997 ◽  
Author(s):  
G. B. Forbes
Keyword(s):  
Young Adults ◽  
Body Composition ◽  
Lean Body Mass ◽  
Body Mass ◽  
Body Fat ◽  
Training Programs ◽  
Published Data ◽  
Additional Information ◽  
Body Fat Content ◽  
Ad Libitum

We assessed changes in body composition in 41 young adults who engaged in various exercise and/or training programs on ad libitum diets. Most of those who gained weight sustained an increase in lean body mass (LBM), and most of those who lost weight lost LBM as well as fat. The change in LBM was directly related to the change in weight, with a regression slope of 0.500. An analysis of published data confirms these findings and, in concert with our data, provides the additional information that the magnitude of the change in body composition in exercising individuals is influenced by body fat content, just as it is for nonexercising individuals.

scholarly journals The Influence of Increased Body Fat or Lean Body Mass on Aerobic Performance

PLoS ONE ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. e95797 ◽  
Author(s):  
Marcin Maciejczyk ◽  
Magdalena Więcek ◽  
Jadwiga Szymura ◽  
Zbigniew Szyguła ◽  
Szczepan Wiecha ◽  
...  
Keyword(s):  
Lean Body Mass ◽  
Body Mass ◽  
Body Fat ◽  
Aerobic Performance
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