scholarly journals Physiological Levels of Melatonin Relate to Cognitive Function and Depressive Symptoms: The HEIJO-KYO Cohort

2015 ◽  
Vol 100 (8) ◽  
pp. 3090-3096 ◽  
Author(s):  
Kenji Obayashi ◽  
Keigo Saeki ◽  
Junko Iwamoto ◽  
Nobuhiro Tone ◽  
Kunihiko Tanaka ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Depressive Symptoms ◽  
Cognitive Function ◽  
Confidence Interval ◽  
Depressed Mood ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Cross Sectional

Context: In contrast with randomized controlled trials, observational studies have suggested that physiological levels of melatonin are reduced in patients with dementia or depression, but the relationship has not been evaluated in large populations. Objective: The objective was to determine the relationships between physiological levels of melatonin and cognitive function and depressive symptoms. Design and Participants: A cohort of 1105 community-dwelling elderly individuals was enrolled in this cross-sectional study (mean age, 71.8 ± 7.1 y). Measures: Urinary 6-sulfatoxymelatonin excretion (UME) and Mini-Mental State Examination (MMSE; n = 935) and Geriatric Depression Scale (GDS; n = 1097) scores were measured as indices of physiological melatonin levels, cognitive function, and depressive symptoms, respectively. Results: With increases in UME quartiles, the prevalence of cognitive impairment (MMSE score ≤ 26) and depressed mood (GDS score ≥ 6) significantly decreased (P for trend = .003 and .012, respectively). In multivariate logistic regression models, after adjusting for confounders such as age, gender, socioeconomic status, physical activity, and sleep/wake cycles, higher UME levels were significantly associated with lower odds ratios (ORs) for cognitive impairment and depressed mood (ORs: Q1 = 1.00; Q2 = 0.88 and 0.76; Q3 = 0.66 and 0.85; Q4 = 0.67 and 0.53; P for trend = .023 and .033, respectively). In addition, the highest UME group showed a significantly lower OR for depressed mood than the lowest UME group (Q4 vs Q1: OR, 0.53; 95% confidence interval, 0.32–0.89; P = .033). UME levels above the median value were significantly associated with a lower OR for cognitive impairment, even after further adjustment for depressive symptoms (OR = 0.74; 95% confidence interval, 0.55–0.99; P = .043). Conclusions: Significant associations of higher physiological melatonin levels with lower prevalence of cognitive impairment and depressed mood were revealed in a large general elderly population. The association between physiological melatonin levels and cognitive function was independent of depressive symptoms.

scholarly journals Identifying the Factors Related to Depressive Symptoms Amongst Community-Dwelling Older Adults with Mild Cognitive Impairment

2019 ◽  
Vol 16 (18) ◽  
pp. 3449 ◽  
Author(s):  
Dan Song ◽  
Doris S.F. Yu ◽  
Polly W.C. Li ◽  
Qiuhua Sun
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Depressive Symptoms ◽  
Mild Cognitive Impairment ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Community Dwelling ◽  
Cross Sectional ◽  
Increased Risk ◽  
Community Dwelling Older Adults

High-level depressive symptoms have been reported in individuals with mild cognitive impairment (MCI), resulting in increased risk of progression to dementia. However, studies investigating the correlates of depressive symptoms among this population are scarce. This study aimed to investigate the significant socio-demographic, lifestyle-related and disease-related correlates of depressive symptoms among this cohort. Cross-sectional data were obtained from a sample of 154 Chinese community-dwelling older adults with MCI. MCI subjects were screened by the Montreal Cognitive Assessment. Depressive symptoms were measured by the Geriatric Depression Scale. Possible correlates of depressive symptoms in individuals with MCI were explored by multiple linear regressions. The prevalence of depressive symptoms among Chinese older adults with MCI was 31.8%. In multiple regression analysis, poor perceived positive social interaction, small social network, low level of physical activity, poor functional status, subjective memory complaint, and poor health perception were correlated with depressive symptoms. The findings highlight that depressive symptoms are sufficient to warrant evaluation and management in older adults with MCI. Addressing social isolation, assisting this vulnerable group in functional and physical activities, and cultivating a positive perception towards cognitive and physical health are highly prioritized treatment targets among individuals with MCI.

scholarly journals Associations between Depressive Symptoms and Satisfaction with Meaningful Activities in Community-Dwelling Japanese Older Adults

2020 ◽  
Vol 9 (3) ◽  
pp. 795
Author(s):  
Michio Maruta ◽  
Hyuma Makizako ◽  
Yuriko Ikeda ◽  
Hironori Miyata ◽  
Atsushi Nakamura ◽  
...  
Keyword(s):  
Older Adults ◽  
Depressive Symptoms ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Cross Sectional ◽  
Significant Difference ◽  
Japanese Older Adults ◽  
And Performance

The aim of this cross-sectional study was to investigate relationships between individuals’ ratings of satisfaction and performance of activities that they found meaningful and depressive symptoms. Data was obtained from 806 older adults (mean age 74.9 ± 6.3 years, women = 63.0%) who participated in a community-based health check survey (Tarumizu Study 2018). Participants selected meaningful activities from 95 activities using the Aid for Decision-Making in Occupation Choice and evaluated their satisfaction and performance. Depressive symptoms were assessed using the 15-item Geriatric Depression Scale (GDS-15) and defined by a GDS-15 score of ≥5. Non-linear logistic regression analyses were used separately by gender to examine the association between satisfaction and performance of meaningful activities and depressive symptoms. The prevalence of depressive symptoms was 15.8%. We found no significant difference between meaningful activity choice between older adults with depressive symptoms and those without, in both men and women. After adjusting for potential covariates, satisfaction was associated with depressive symptoms in both men (OR 0.52, 95% CI 0.35–0.77) and women (OR 0.67, 95% CI 0.49–0.91), but performance was limited in women (OR 0.87, 95% CI 0.77–0.99). Our findings suggest that depressive symptoms are associated with satisfaction in meaningful activities regardless of activity categories.

scholarly journals Relationships between cognitive leisure activities and cognitive function in older adults with depressive symptoms: a cross-sectional study

BMJ Open ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. e032679 ◽  
Author(s):  
Min Ji Kim ◽  
Kota Tsutsumimoto ◽  
Takehiko Doi ◽  
Sho Nakakubo ◽  
Satoshi Kurita ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Depressive Symptoms ◽  
Cognitive Function ◽  
Scale Score ◽  
Leisure Activities ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Sectional Study ◽  
Cross Sectional

ObjectivesThe current study aimed to elucidate the associations between cognitive leisure activities and cognitive function in an older population stratified by having or not having depressive symptoms.DesignA retrospective cross-sectional study based on a self-report questionnaire.SettingAnnual health check-ups in a rural community in Japan.ParticipantsA total of 11 010 community-dwelling older adults aged ≥65 years (mean age: 74.0±5.4 years) was examined. Participants with missing data for the main outcome (n=1630) were excluded.Outcome measuresCognitive impairment was defined as at least 1.5 SD below the reference threshold (age-adjusted and education-adjusted score) on two of more of the tests in the National Center for Geriatrics and Gerontology-Functional Assessment Tool. Depressive symptoms were defined by a 15-item Geriatric Depression Scale score ≥6. We assessed the frequency of participation in cognitive leisure activities using the validated scale (score: 0–42). A score of ≥8 points was defined as frequent participation in cognitive leisure activities.ResultsA total of 12.6% (n=1186) of the participants had depressive symptoms. There was a significant association between cognitive leisure activities and cognitive impairment in older adults (adjusted OR=0.77, 95% CI=0.65 to 0.94). In older adults with depressive symptoms, a higher frequency of cognitive leisure activities was negatively associated with cognitive impairment (adjusted OR=0.45, 95% CI=0.28 to 0.70). In contrast, there was no significant association in older adults without depressive symptoms (adjusted OR=0.85, 95% CI=0.70 to 1.02).ConclusionsEngaging in cognitive leisure activities in late life is associated with better cognitive function in older adults with depressive symptoms.

scholarly journals Associations between depressive symptoms and geriatric syndromes in community-dwelling older adults in Japan: a cross-sectional study

2020 ◽  
Author(s):  
Masakazu Imaoka ◽  
Hidetoshi Nakao ◽  
Misa Nakamura ◽  
Fumie Tazaki ◽  
Mitsumasa Hida ◽  
...  
Keyword(s):  
Older Adults ◽  
Depressive Symptoms ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Geriatric Syndromes ◽  
Sectional Study ◽  
Cross Sectional ◽  
Community Dwelling Older Adults

Abstract Background It is estimated that 7.2% of community-dwelling older adults in worldwide have major depression. This cross-sectional study aimed to investigate the relationship between geriatric syndromes and depressive symptoms. Methods Data were obtained from 363 older adults (mean age 73.6 ± 6.6 years; women = 75.8%) who participated in a community-based health check. Depressive symptoms were assessed using the 15-item Geriatric Depression Scale (GDS-15). Depression was defined as a GDS-15 score of ≥ 5. Further, geriatric syndromes in participants—such as frailty, sarcopenia, and locomotive syndrome—were assessed. Results There was a 28.1% prevalence of depressive symptoms. In a logistic regression analysis with depressive symptoms as the dependent variable, both pre-frailty (odds ratio [OR] 1.85, 95% confidence interval [CI] 1.09–3.01) and frailty (OR 5.45, 95% CI 2.23–13.31) were found to be significantly higher in the depressive group. Conclusions Our findings suggest that depressive symptoms are associated with frailty and pre-frailty in community-dwelling older adults in Japan.

scholarly journals Watching sports and depressive symptoms among older adults: a cross-sectional study from the JAGES 2019 survey

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Taishi Tsuji ◽  
Satoru Kanamori ◽  
Ryota Watanabe ◽  
Meiko Yokoyama ◽  
Yasuhiro Miyaguni ◽  
...  
Keyword(s):  
Older Adults ◽  
Depressive Symptoms ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Mail Survey ◽  
Prevalence Ratio ◽  
Average Frequency ◽  
Evaluation Study ◽  
Cross Sectional Study ◽  
Cross Sectional

AbstractThe current study investigated the relationship between the frequency of watching sports and depressive symptoms among older adults. This study used cross-sectional data from the Japan Gerontological Evaluation Study, a nationwide mail survey of 21,317 older adults. Depressive symptoms were defined as a Geriatric Depression Scale score of ≥ 5. Participants were queried regarding the average frequency at which they watched sports on-site and via TV/Internet over the past year. Among the 21,317 participants, 4559 (21.4%) had depressive symptoms, while 4808 (22.6%) and 16,576 (77.8%) watched sports on-site and via TV/Internet at least once a year, respectively. Older adults who watched sports on-site a few times/year (prevalence ratio, 0.70; 95% confidence interval, 0.65–0.74) or 1–3 times/month (0.66, 0.53–0.82) were less likely to have depressive symptoms compared to non-spectators after adjusting for frequency of playing sports, exercise activities, and other potential confounders. Meanwhile, a dose–response relationship was confirmed for watching via TV/Internet (prevalence ratio of 0.86, 0.79, and 0.71 for a few times/year, 1–3 times/month, and ≥ 1 time/week, respectively). This study suggested that watching sports on-site or via TV/Internet, regardless of whether they regularly engage in sports, may reduce the risk of depressive symptoms among older adults.

scholarly journals Assessing the Impact of a Hilly Environment on Depressive Symptoms among Community-Dwelling Older Adults in Japan: A Cross-Sectional Study

2021 ◽  
Vol 18 (9) ◽  
pp. 4520
Author(s):  
Takafumi Abe ◽  
Kenta Okuyama ◽  
Tsuyoshi Hamano ◽  
Miwako Takeda ◽  
Masayuki Yamasaki ◽  
...  
Keyword(s):  
Older Adults ◽  
Depressive Symptoms ◽  
Depression Scale ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Rural Setting ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Impact ◽  
Community Dwelling Older Adults

Although some neighborhood environmental factors have been found to affect depressive symptoms, few studies have focused on the impact of living in a hilly environment, i.e., land slope, on depressive symptoms among rural older adults. This cross-sectional study aimed to investigate whether a land slope is associated with depressive symptoms among older adults living in rural areas. Data were collected from 935 participants, aged 65 years and older, who lived in Shimane prefecture, Japan. Depressive symptoms were assessed using the Zung Self-Rating Depression Scale (SDS) and defined on the basis of an SDS score ≥ 40. Land slopes within a 400 m network buffer were assessed using geographic information systems. Odds ratios (ORs) with 95% confidence intervals (CIs) of depressive symptoms were estimated using logistic regression. A total of 215 (23.0%) participants reported depressive symptoms. The land slope was positively associated with depressive symptoms (OR = 1.04; 95% CI = 1.01–1.08) after adjusting for all confounders. In a rural setting, living in a hillier environment was associated with depressive symptoms among community-dwelling older adults in Japan.

scholarly journals Physical activity and depressive symptoms in community-dwelling elders from southern Brazil

2011 ◽  
Vol 33 (2) ◽  
pp. 165-170 ◽  
Author(s):  
César L. Reichert ◽  
César L. Diogo ◽  
José L. Vieira ◽  
Roberta R. Dalacorte
Keyword(s):  
Physical Activity ◽  
Depressive Symptoms ◽  
Linear Trend ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Population Based ◽  
Community Dwelling ◽  
Active Group ◽  
Lower Prevalence ◽  
Cross Sectional

OBJECTIVE: To determine the existence of a relationship between physical activity and depressive symptoms in community-dwelling elders. METHOD: This is a cross-sectional, population-based study, which included 379 community-dwelling elders from Novo Hamburgo, state of RS, Brazil. The level of physical activity was estimated using the International Physical Activity Questionnaire and depressive symptoms were diagnosed according to the Yesavage Geriatric Depression Scale. The association between the level of physical activity and depressive symptoms was analyzed by logistic regression. RESULTS: A tendency towards a lower prevalence of depressive symptoms was observed in individuals with higher levels of physical activity, both in the sample as a whole as well as among men, but not among women (p for linear trend 0.04, 0.03 and 0.36, respectively). The odds ratio of the presence of depressive symptoms in the very active group, as compared against that of the insufficiently active group was 0.32 (95% CI: 0.12-0.86) for men and 0.76 (95% CI: 0.39-1.46) for women. CONCLUSION: In this population of aged individuals, more intense physical activity is related to a lower prevalence of depressive symptoms. As shown by gender stratification, physical activity is inversely related to depressive symptoms in men, albeit not in women.

Differential associations between depression and cognitive function in MCI and AD: a cross-sectional study

2019 ◽  
Vol 31 (08) ◽  
pp. 1151-1158 ◽  
Author(s):  
Chang Hyun Lee ◽  
Do Hoon Kim ◽  
Yoo Sun Moon
Keyword(s):  
Executive Function ◽  
Cognitive Function ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Neuropsychological Screening ◽  
Screening Battery ◽  
Clinical Research Center ◽  
Sectional Analysis

ABSTRACTObjective:Despite the possibility that cognitive deficits associated with depression may have different patterns depending on the level of neurocognitive impairment, there remains no clear evidence of this. This study aimed to investigate the differential association between depression and cognitive function in patients with mild cognitive impairment (MCI) and Alzheimer’s disease (AD).Methods:A cross-sectional analysis was performed of data from 1,724 patients with MCI and 1,247 patients with AD from the Clinical Research Center for Dementia in Korea. Depression was assessed using the Korean form of the Geriatric Depression Scale, and cognition was measured using the Seoul Neuropsychological Screening Battery, which includes five domains (attention, language and related function, visuospatial function, memory, and frontal/executive function).Results:Significant differences were found between the two groups (non-depressed vs. depressed) in visuospatial, memory, and executive function domains in the MCI group, as well as in the attention domain in the AD group. The association between depressive symptoms and cognitive function was significantly greater in patients with MCI than in those with AD. These associations were more pronounced in memory and executive function.Conclusion:Our findings suggest that the association between depression and decreased cognitive function is more pronounced in MCI than AD.

scholarly journals PREVALENCE AND FACTORS ASSOCIATED WITH ABUSE AND LIKELY DEPENDENCE OF ALCOHOL AMONG ELDERLY

2019 ◽  
Vol 28 ◽  
Author(s):  
Mariana Silva Freitas Guimarães ◽  
Darlene Mara dos Santos Tavares
Keyword(s):  
Depressive Symptoms ◽  
Alcohol Dependence ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Older Americans ◽  
Factors Associated ◽  
Health Action

ABSTRACT Objective: verify the prevalence of abuse and probable alcohol dependence in the elderly; describe sociodemographic and clinical characteristics of the elderly; and verify the factors associated with alcohol abuse and probable dependence in the elderly. Method: cross-sectional study, observational, domiciliary survey type, conducted with 614 elderly people living in the urban area of the city of Uberaba, Brazil. The Mini Mental State Examination, sociodemographic instrument, Older Americans Resources and Services Questionnaire, Geriatric Depression Scale and Michigan Alcoholism Screening Test - Geriatric Version were used. Statistical analysis was performed in the Statiscal Package for Social Sciences. Results: the prevalence of abuse and probable alcohol dependence was 26.5%. Among the elderly with abuse and probable dependence on alcohol, there was predominance of males, 60 |- 70 years old, who lived with a spouse or partner, had 1 |- 5 years of schooling, individual monthly income from 1 -| 3 minimum wages, five or more morbidities and no indication of depressive symptoms. Abuse and probable alcohol dependence were associated with males and the presence of depressive symptoms. Conclusion: the study reinforces the need to identify early abuse and probable alcohol dependence in the elderly and to invest in health action strategies for the purpose of health promotion, disease prevention and rehabilitation of the elderly.

Music Training Improves Depressed Mood Symptoms in Elderly People: A Randomized Controlled Trial

2019 ◽  
Vol 92 (1) ◽  
pp. 115-133 ◽  
Author(s):  
Michele Biasutti ◽  
Anthony Mangiacotti
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Function ◽  
Depressed Mood ◽  
Mini Mental State Examination ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Control Group ◽  
Geriatric Depression ◽  
Music Training ◽  
State Examination

The effectiveness of music training on depressed mood and general cognitive function in elderly participants is verified in this study. Music activities consisted of improvisation exercises for stimulating interpersonal skills, mood, and cognitive functions. A mixed research method was adopted, including standardized measures (Mini-Mental State Examination and Geriatric Depression Scale) and follow-up semistructured interviews. The research design included pre- and postevaluation with randomized experimental and control groups. Participants were 45 care residents aged 62 to 95, healthy and with cognitive impairment. Results revealed a significant improvement in depression index (Geriatric Depression Scale) for the experimental period ( t = 1.450; p < .005; d = 0.453) while the control group had no improvement ( t = 0.080; p > .1; d = 0.025). In addition, a significant improvement was found in the cognitive level (Mini-Mental State Examination) for the experimental ( t = 2.300; p < .005; d =  0.668) than the control group that had a significant reduction ( t = 1.240; p < .05; d = 0.273). This study provides evidence that music training has a positive impact on depressed mood and general cognitive function in elderly participants. These types of music training sessions could provide aid to control the symptoms of depression, delay the deterioration of cognitive function, and enhance social–cognitive function, especially in individuals presenting with cognitive impairment.

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