scholarly journals The Influence of Patient Age on Thyroid Nodule Formation, Multinodularity, and Thyroid Cancer Risk

2015 ◽  
Vol 100 (12) ◽  
pp. 4434-4440 ◽  
Author(s):  
Norra Kwong ◽  
Marco Medici ◽  
Trevor E. Angell ◽  
Xiaoyun Liu ◽  
Ellen Marqusee ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Thyroid Nodule ◽  
Nodule Formation ◽  
Patient Age ◽  
Patient Âgé ◽  
Thyroid Cancer Risk

scholarly journals Approach to the Patient with a Cytologically Indeterminate Thyroid Nodule

2008 ◽  
Vol 93 (11) ◽  
pp. 4175-4182 ◽  
Author(s):  
Erik K. Alexander
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Thyroid Nodule ◽  
Surgical Procedures ◽  
Fine Needle Aspiration ◽  
Thyroid Nodules ◽  
Needle Aspiration ◽  
Follicular Neoplasm ◽  
Fine Needle ◽  
Thyroid Cancer Risk

Background: Fine-needle aspiration remains the primary diagnostic intervention for the evaluation of most thyroid nodules larger than 1–1.5 cm. Although most aspirates provide diagnostic cytology, approximately 15–25% will be classified indeterminate (often referred to as follicular neoplasm, suspicious for carcinoma, or atypical). In such cases, abnormal cellular findings preclude interpretation of benignity, although only a minority will prove cancerous upon final histopathology. Nonetheless, patients with indeterminate aspirates are commonly referred for consideration of hemi- or near-total thyroidectomy. Recently, improved understanding and novel investigation of clinical, radiological, cytological, and molecular factors has allowed improved stratification of cancer risk. Conclusion: Although surgery continues to be commonly recommended, strategies for such patients should increasingly seek to define treatment based on the estimation of an individual’s thyroid cancer risk in comparison with associated operative risk and morbidity. In doing so, the rate of unnecessary surgical procedures and associated complications can be reduced.

Thyroid Cancer Risk in Relation to Thyroid Nodule Location

2021 ◽  
Vol 33 (9) ◽  
pp. 394-396
Author(s):  
Erivelto Volpi ◽  
Antonio Rahal
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Thyroid Nodule ◽  
Thyroid Cancer Risk

Increased thyroid cancer risk in acromegaly

2013 ◽  
Author(s):  
Selcuk Dagdelen ◽  
Nese Cinar ◽  
Tomris Erbas
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Thyroid Cancer Risk

scholarly journals Fertility Drugs Associated with Thyroid Cancer Risk: A Systematic Review and Meta-Analysis

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
QingAn Yu ◽  
XiaoYing Lv ◽  
KunPeng Liu ◽  
DaKun Ma ◽  
YaoHua Wu ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Clomiphene Citrate ◽  
Positive Association ◽  
Female Infertility ◽  
Cochrane Library ◽  
Significant Positive Association ◽  
Fertility Drugs ◽  
Increased Risk ◽  
Thyroid Cancer Risk

Associations have been demonstrated between fertility drugs and a variety of hormone-sensitive carcinomas. The purpose of this study was to determine the relationship between fertility drugs used in the treatment of female infertility and the risk of thyroid cancer. To investigate the clinical significance of fertility drugs used for the treatment of female infertility and the risk associated with thyroid cancer, we performed a literature search using PubMed, MEDLINE, the Cochrane Library, the Web of Science, and EBSCOHOST for comparative studies published any time prior to July 21, 2017. The studies included women who were treated for infertility with fertility drugs, such as clomiphene citrate, gonadotropins, or other unspecified fertility agents, which reported the incidence of thyroid cancer as the main outcome. Eight studies were included in the meta-analyses. Among women with infertility, there was a significant positive association between thyroid cancer risk and the use of fertility drugs (relative risk [RR] = 1.35; 95% confidence interval [CI] 1.12–1.64; P=0.002). Additionally, among women with infertility, the use of clomiphene citrate was associated with an increased risk of thyroid cancer compared to women who did not use fertility drugs (RR = 1.45; 95% CI 1.12–1.88; P=0.005). After pooling results, we found that the parity status of infertile women using fertility drugs was not associated with thyroid cancer risk (RR = 0.99; 95% CI 0.61–1.58, P=0.95). In summary, clomiphene citrate (the most commonly used fertility drug) and other fertility drugs are associated with an increased risk of thyroid cancer.

Contribution of industrial density and socioeconomic status to the spatial distribution of thyroid cancer risk in Hangzhou, China

2018 ◽  
Vol 613-614 ◽  
pp. 679-686 ◽  
Author(s):  
Xufeng Fei ◽  
Zhaohan Lou ◽  
George Christakos ◽  
Qingmin Liu ◽  
Yanjun Ren ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Spatial Distribution ◽  
Thyroid Cancer ◽  
Cancer Risk ◽  
Thyroid Cancer Risk

scholarly journals A Study of Artificial Sweeteners and Thyroid Cancer Risk

2020 ◽  
Vol 12 (8) ◽  
pp. 492-498
Author(s):  
Navdeep Singh ◽  
Sandeep Singh Lubana ◽  
Saurabh Arora ◽  
Issac Sachmechi
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Artificial Sweeteners ◽  
Thyroid Cancer Risk

scholarly journals An overall and dose-response meta-analysis for thyrotropin and thyroid cancer risk by histological type

Oncotarget ◽  
2016 ◽  
Vol 7 (30) ◽  
pp. 47750-47759 ◽  
Author(s):  
Na Hu ◽  
Zhan-Ming Li ◽  
Jin-Feng Liu ◽  
Zhen-Zhen Zhang ◽  
Li-Shun Wang
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Dose Response ◽  
Meta Analysis ◽  
Histological Type ◽  
Thyroid Cancer Risk

scholarly journals The effect of raw vegetable and fruit intake on thyroid cancer risk among women: a case–control study in South Korea

2012 ◽  
Vol 109 (1) ◽  
pp. 118-128 ◽  
Author(s):  
Su Kyoung Jung ◽  
Kirang Kim ◽  
Kyung Tae ◽  
Gu Kong ◽  
Mi Kyung Kim
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Case Control Study ◽  
Early Stage ◽  
Conditional Logistic Regression ◽  
Case Control ◽  
Dietary Factors ◽  
Inverse Association ◽  
Thyroid Cancer Risk ◽  
Control Study

Thyroid cancer is the most common cancer among Korean women. However, there are few data on dietary factors related to thyroid cancer risk. The objective of the present study was to evaluate the association between raw vegetables and fruits intake and thyroid cancer in a case–control study. We included 111 histologically confirmed malignant thyroid cancer cases and 115 benign cases. Controls who did not have nodules in thyroid ultrasonography were matched to cases by age ( ± 2 years). Food and nutrient intakes were estimated using a quantitative FFQ with 121 items. Conditional logistic regression analysis was used to obtain OR and corresponding 95 % CI. The intake of total vegetables was not associated with malignant thyroid cancer, but inversely associated with benign cases. High raw vegetable intake was inversely associated with thyroid cancer risk both in malignant and benign cases (P for trend = 0·01 in both malignant and benign cases). Among fruits, persimmon intake had an inverse association with thyroid cancer risk in both malignant and benign cases (P for trend = 0·06 in malignant cases; P for trend = 0·01 in benign cases) and tangerine intake had an inverse association in malignant cases (P for trend = 0·03). The frequency of consumption of raw vegetables and persimmon also had a consistent inverse association in both malignant and benign cases. These results suggest that high consumption of raw vegetables, persimmons and tangerines may decrease thyroid cancer risk and help prevent early-stage thyroid cancer.

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