The Action of the Eyecup Muscles of the Crab, Carcinus, During Optokinetic Movements

1968 ◽  
Vol 49 (2) ◽  
pp. 223-250
Author(s):  
M. BURROWS ◽  
G. A. HORRIDGE

1. The actions of the nine eyecup muscles of the crab during horizontal optokinetic movements are described. 2. Each muscle includes a wide spectrum of fibre types, ranging from phasic, with sarcomere lengths of 3-4 µm., through intermediate, to tonic fibres with sarcomeres of 10-12 µm. Each muscle receives at least one slow and one fast motoneuron, but no inhibitory supply. The slow axons predominantly innervate the tonic muscle fibres while the fast axons innervate the phasic ones. 3. Slow movement and the position of the eyecup in space are controlled by the frequency of slow motoneuron discharges. All muscles collaborate at every position. The phasic system is recruited during rapid eyecup movements of large amplitude. 4. In optokinetic nystagmus the exact form of the impulse sequences are described for each muscle. They are the consequence of a visually driven central programme which takes no account of the movement which it generates. Movements in opposite directions involve different central programmes; the one is not merely the reverse of the other. There is no effective proprioceptive feedback from the eyecup joint or from muscle tension receptors.

2018 ◽  
Vol 15 (3) ◽  
pp. 421-442
Author(s):  
R. Larry Todd

History has often viewed Brahms as a Janus-faced composer who turned his gaze backward to contemplate the accumulated riches of music history even as he sought late in his career to exploit new means of musical expression. On the one hand, he habitually collected passages from a long line of composers that breached the traditional prohibition against parallel fifths and octaves; he exchanged ideas with musicologists such as Nottebohm, Mandyczewski and Adler, and read early issues of the Vierteljahrsschrift für Musikwissenschaft; and he indulged from time to time in a distinctive musical historicism. But on the other hand, his music was embraced for showing a way forward for a number of next-generation composers who would contend with twentieth-century modernism, most notably of course Schoenberg, in his essay ‘Brahms the Progressive’, but also Anton von Webern, whose transitional Passacaglia op. 1 was unthinkable without the precedent of Brahms’s op. 90, and whose aphoristic miniatures betrayed the concentrated expression and opening up of register in Brahms’s late Klavierstücke.This essay considers one still relatively little-explored facet of Brahms’s historical gaze – his use of modes in his later music, and their potential for creating alternative means of musical organization that challenged, and yet were somehow compatible with, tonality. Examples considered include the first movement of the Clarinet Trio op. 114 and slow movement of the String Quintet no. 2 op. 111. Unlike Brahms’s earlier compositions that treat modes as signifiers of a style of folk music or simulated folk music, the later instrumental works seem to juxtapose principles of modal organization within the context of tonal compositions. Thus, in the first movement of the Clarinet Trio, eerie passages in fauxbourdon impress as allusions to a distant, archaic musical other, as if Brahms the historian were searching for the distant roots of his musical aesthetic.


2019 ◽  
Vol 62 (3) ◽  
pp. 79-92
Author(s):  
Aleksandra Zoric

Although cannabis has been used for thousands of years for medical and recreational purposes, the debate on its introduction as a medical product has only recently begun. That discussion was preceded by the discovery and explanation of the active components in cannabis on the one hand, and the discovery of the endocannabinoid system in mammals on the other. Numerous studies over the past thirty years have focused on their further examination, and scarce clinical studies show the beneficial effects of cannabis on the wide spectrum of diseases. The question is why, thirty years after the discovery of the endocannabinoid system and the CB1 and CB2 receptors, as well as the positive results in cannabis administration in a wide range of diseases, extensive clinical studies and relevant explanations are still lacking. On the other hand, one may wonder if something important is being denied to patients who might find cannabis use beneficial? Therefore, it is important to analyze several different problems. What is the subject of the dispute, and which cannabis derivatives are allowed? Why do we not have relevant clinical studies, that is, all of those are of a very limited extent? How are clinical studies conducted? To whom are these derivatives intended and are there ethical dilemmas regarding their use?


2015 ◽  
Vol 58 (2) ◽  
pp. 107-144
Author(s):  
MOHAMMAD NAFISSI

AbstractModern scholarly accounts of ancient Greece and more particularly the research programme which broadly frames Moses Finley's contributions are generally traced to George Grote's politically anchored History of Greece and re-evaluationof Athenian democracy. However, notwithstanding their far-reachinginfluence, Finley's writings display an exceptional complexity that has invited a wide spectrum of contradictory interpretations and evaluations. This article extends my previous study of Finley's Athens by locating and exploring an unresolved and still significant debate that he held with himself through the major political and economic writings of his last period (1973–85). It thereby discloses the normative, theoretical, and empirical demands that, on the one hand, informed his account of ‘the ancient economy’ and necessitated its overall incoherence, and, on the other, allowed for a coherently normative account of ‘ancient politics’. In the process, some notable claims about Finley's work and politics are clarified, and it is shown why ‘Finley's ghost is [still] everywhere’ even though the short twentieth century that spanned his life, posed its major questions and set the context and constraints of his answers, has long been over.


1975 ◽  
Vol 26 ◽  
pp. 395-407
Author(s):  
S. Henriksen

The first question to be answered, in seeking coordinate systems for geodynamics, is: what is geodynamics? The answer is, of course, that geodynamics is that part of geophysics which is concerned with movements of the Earth, as opposed to geostatics which is the physics of the stationary Earth. But as far as we know, there is no stationary Earth – epur sic monere. So geodynamics is actually coextensive with geophysics, and coordinate systems suitable for the one should be suitable for the other. At the present time, there are not many coordinate systems, if any, that can be identified with a static Earth. Certainly the only coordinate of aeronomic (atmospheric) interest is the height, and this is usually either as geodynamic height or as pressure. In oceanology, the most important coordinate is depth, and this, like heights in the atmosphere, is expressed as metric depth from mean sea level, as geodynamic depth, or as pressure. Only for the earth do we find “static” systems in use, ana even here there is real question as to whether the systems are dynamic or static. So it would seem that our answer to the question, of what kind, of coordinate systems are we seeking, must be that we are looking for the same systems as are used in geophysics, and these systems are dynamic in nature already – that is, their definition involvestime.


Author(s):  
Stefan Krause ◽  
Markus Appel

Abstract. Two experiments examined the influence of stories on recipients’ self-perceptions. Extending prior theory and research, our focus was on assimilation effects (i.e., changes in self-perception in line with a protagonist’s traits) as well as on contrast effects (i.e., changes in self-perception in contrast to a protagonist’s traits). In Experiment 1 ( N = 113), implicit and explicit conscientiousness were assessed after participants read a story about either a diligent or a negligent student. Moderation analyses showed that highly transported participants and participants with lower counterarguing scores assimilate the depicted traits of a story protagonist, as indicated by explicit, self-reported conscientiousness ratings. Participants, who were more critical toward a story (i.e., higher counterarguing) and with a lower degree of transportation, showed contrast effects. In Experiment 2 ( N = 103), we manipulated transportation and counterarguing, but we could not identify an effect on participants’ self-ascribed level of conscientiousness. A mini meta-analysis across both experiments revealed significant positive overall associations between transportation and counterarguing on the one hand and story-consistent self-reported conscientiousness on the other hand.


2005 ◽  
Vol 44 (03) ◽  
pp. 107-117
Author(s):  
R. G. Meyer ◽  
W. Herr ◽  
A. Helisch ◽  
P. Bartenstein ◽  
I. Buchmann

SummaryThe prognosis of patients with acute myeloid leukaemia (AML) has improved considerably by introduction of aggressive consolidation chemotherapy and haematopoietic stem cell transplantation (SCT). Nevertheless, only 20-30% of patients with AML achieve long-term diseasefree survival after SCT. The most common cause of treatment failure is relapse. Additionally, mortality rates are significantly increased by therapy-related causes such as toxicity of chemotherapy and complications of SCT. Including radioimmunotherapies in the treatment of AML and myelodyplastic syndrome (MDS) allows for the achievement of a pronounced antileukaemic effect for the reduction of relapse rates on the one hand. On the other hand, no increase of acute toxicity and later complications should be induced. These effects are important for the primary reduction of tumour cells as well as for the myeloablative conditioning before SCT.This paper provides a systematic and critical review of the currently used radionuclides and immunoconjugates for the treatment of AML and MDS and summarizes the literature on primary tumour cell reductive radioimmunotherapies on the one hand and conditioning radioimmunotherapies before SCT on the other hand.


2017 ◽  
Vol 47 (188) ◽  
pp. 487-494
Author(s):  
Daniel Mullis

In recent years, political and social conditions have changed dramatically. Many analyses help to capture these dynamics. However, they produce political pessimism: on the one hand there is the image of regression and on the other, a direct link is made between socio-economic decline and the rise of the far-right. To counter these aspects, this article argues that current political events are to be understood less as ‘regression’ but rather as a moment of movement and the return of deep political struggles. Referring to Jacques Ranciere’s political thought, the current conditions can be captured as the ‘end of post-democracy’. This approach changes the perspective on current social dynamics in a productive way. It allows for an emphasis on movement and the recognition of the windows of opportunity for emancipatory struggles.


1996 ◽  
pp. 13-23
Author(s):  
Mykhailo Babiy

Political ideological pluralism, religious diversity are characteristic features of modern Ukrainian society. On the one hand, multiculturalism, socio-political, religious differentiation of the latter appear as important characteristics of its democracy, as a practical expression of freedom, on the other - as a factor that led to the deconsocialization of society, gave rise to "nodal points" of tension, confrontational processes, in particular, in political and religious spheres.


2003 ◽  
pp. 15-26
Author(s):  
P. Wynarczyk
Keyword(s):  
The Core ◽  

Two aspects of Schumpeter' legacy are analyzed in the article. On the one hand, he can be viewed as the custodian of the neoclassical harvest supplementing to its stock of inherited knowledge. On the other hand, the innovative character of his works is emphasized that allows to consider him a proponent of hetherodoxy. It is stressed that Schumpeter's revolutionary challenge can lead to radical changes in modern economics.


2018 ◽  
pp. 49-68 ◽  
Author(s):  
M. E. Mamonov

Our analysis documents that the existence of hidden “holes” in the capital of not yet failed banks - while creating intertemporal pressure on the actual level of capital - leads to changing of maturity of loans supplied rather than to contracting of their volume. Long-term loans decrease, whereas short-term loans rise - and, what is most remarkably, by approximately the same amounts. Standardly, the higher the maturity of loans the higher the credit risk and, thus, the more loan loss reserves (LLP) banks are forced to create, increasing the pressure on capital. Banks that already hide “holes” in the capital, but have not yet faced with license withdrawal, must possess strong incentives to shorten the maturity of supplied loans. On the one hand, it raises the turnovers of LLP and facilitates the flexibility of capital management; on the other hand, it allows increasing the speed of shifting of attracted deposits to loans to related parties in domestic or foreign jurisdictions. This enlarges the potential size of ex post revealed “hole” in the capital and, therefore, allows us to assume that not every loan might be viewed as a good for the economy: excessive short-term and insufficient long-term loans can produce the source for future losses.


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