Syringe Pump Design

1986 ◽  
Vol 15 (4) ◽  
pp. 171-174 ◽  
Author(s):  
Paul Wadham

With the evolution of special care baby, intensive care, and coronary care units over the last decade, there has developed a need for greater accuracy in the control of increasingly potent infusions. The design of bedside syringe pump infusers that administer the contents of a syringe to a patient at a constant and predetermined rate will be considered in terms of their ergonomics, control, and safety. Syringe pump design has evolved over the past few years from simple mechanised forms of syringe driving to very sophisticated and precisely-controlled drive systems capable of high volumetric accuracy over a wide range of clinical conditions and sustained for long time periods. This has led to the development of new and critical forms of drug therapy. In addition, important progress has been made in the safety and reliability aspects of syringe pump design. Modern syringe pumps are expected to have fail-safe electronics to protect the patient in the event of a fault occurring. With the advent of modern microprocessor techniques, future syringe pumps can be expected to incorporate further sophisticated operational and safety enhancements, whilst remaining simple to operate. Typical safety enhancements could include the incorporation of a variable pressure sensor to protect against unwanted pressure build up in the IV line, the use of absolute linear encoding techniques for control and monitoring of the infusion, and the increasing use of self-tests and diagnostics to aid the user. Operational enhancements could include the ability to support pharmacokinetic techniques, as well as closed loop drug therapy and remote computer control. Whilst this suggests that infusion therapy might become too sophisticated for day to day use, comprehensive interactive instructions and diagnostic aids would contribute greatly to ease of use. Good user training will be of increasing importance to maximize the benefits of the advances in syringe pump design.

2020 ◽  
Vol 99 (5) ◽  
pp. 493-497
Author(s):  
M. M. Aslanova ◽  
T. V. Gololobova ◽  
K. Yu. Kuznetsova ◽  
Tamari R. Maniya ◽  
D. V. Rakitina ◽  
...  

Introduction. The purpose of our work was to justify the need to improve the legislative, regulatory and methodological framework and preventative measures in relation to the spread of parasitic infections in the provision of medical care. There is a wide range of pathogens of parasitic infestations that are transmitted to humans through various medical manipulations and interventions carried out in various medical institutions. Contaminated care items and furnishings, medical instruments and equipment, solutions for infusion therapy, medical personnel’s clothing and hands, reusable medical products, drinking water, bedding, suture and dressing materials can serve as a major factor in the spread of parasitic infections in the provision of medical care. Purpose of research is the study of the structure and SMP of parasitic origin, circulating on the objects of the production environment in multi-profile medical and preventive institutions of stationary type in order to prevent the occurrence of their spread within medical institutions. Material and methods. The material for the study was flushes taken from the production environment in 3 multi-profile treatment and prevention institutions of inpatient type: a multi-specialty hospital, a maternity hospital and a hospital specializing in the treatment of patients with intestinal diseases for the eggs of worms and cysts of pathogenic protozoa. Results. During the 2-year monitoring of medical preventive institutions, a landscape of parasitic contamination was found to be obtained from the flushes taken from the production environment objects in the premises surveyed as part of the research work. Discussions. In the course of research, the risk of developing ISMP of parasitic origin was found to be determined by the degree of epidemiological safety of the hospital environment, the number and invasiveness of treatment and diagnostic manipulations and various medical technologies. Conclusion. It is necessary to conduct an expert assessment of regulatory and methodological documents in the field of epidemiological surveillance and sanitary and hygienic measures for the prevention of medical aid related infections of parasitic origin, to optimize the regulatory and methodological base, to develop a number of preventive measures aimed at stopping the spread of parasitic infections in the medical network.


Author(s):  
O. Y. Balalaieva ◽  

The purpose of the article is to study the dynamics of electronic dictionaries development abroad and in Ukraine using methods of analysis of scientific sources, comparison, generalization and systematization. Electronic dictionaries have been found to be a relatively new phenomenon in the lexicographic market, evolving from machine-readable dictionaries, exact copies of paper editions to complex digital lexicographic systems with a powerful arsenal of functions over the decades. The stages of development of autonomous and online dictionaries are described. Electronic dictionaries due to the advanced search capabilities, speed, simplicity, ease of use, accessibility and compactness have gained popularity among a wide range of users. Today they are used in many spheres of human activity – scientific, educational, professional, everyday communication. However, the analysis of the current level of development of Ukrainian electronic resources indicates a shortage of electronic dictionaries both common and terminological vocabulary. The lack of electronic dictionaries is due to a number of objective problems, both practical and theoretical, that is why research in the field of domestic computer lexicography is a promising area of further research.


MRS Bulletin ◽  
2003 ◽  
Vol 28 (6) ◽  
pp. 424-427 ◽  
Author(s):  
Agnès Aymonier ◽  
Eric Papon

AbstractSoft reactive adhesives (SRAs) are polymer-based materials (e.g., polyurethanes, polysiloxanes, polydienes) designed to be further vulcanized or slightly cross-linked through external activation (heat, moisture, oxygen, UV–visible irradiation, etc.), either at the time of their application or within a subsequent predefined period. They are used mainly as mastics, or sealing compounds, in a wide range of industrial and commercial fields such as construction, footwear, and the automotive industry. Generally deposited as thick films, SRAs behave as structural adhesives; their low elastic moduli accommodate large strains between the bonded parts without incurring permanent damage. Other outstanding attributes of SRAs are their resistance to solvents, their ability to withstand aggressive environments, and their ease of use. This article discusses examples of SRAs and, more specifically, shows how the cross-linking chemistry, mainly through step-growth polymerization, provides their primary advantages.


2015 ◽  
Vol 9 (2) ◽  
pp. 107-116 ◽  
Author(s):  
Shao‐Kai Tseng ◽  
Chih‐Chien Tseng ◽  
Tian‐Hua Liu ◽  
Jui‐Ling Chen

Author(s):  
Mehmet Zeki Gunluoglu ◽  
Tugrul Ormeci ◽  
Selva Sen

Abstract: Rapid developments and increasing technological knowledge have changed perspectives on ultrasonography. Previously, ultrasonography was used to evaluate chest wall pathologies, to distinguish between pleural effusion and consolidation, to evacuate pleural effusion, or to evaluate diaphragm movement. Today, it is also used in a wide range of pleural and parenchymal diseases. Ultrasonography is not just used in the emergency department and the intensive care units. It is also utilized in many clinical branches dealing with the respiratory system—due to its ease of use, fast access, price advantage, non-radiation exposure, higher diagnostic sensitivity, and specificity in many clinical situations—and has become a part of the examination. In this review, we have assessed not just transthoracic ultrasonography but also more focal and targeted sonographic applications, such as the endobronchial ultrasound and esophageal ultrasound.


2017 ◽  
Vol 2 (2) ◽  
Author(s):  
Roland A. Snijder ◽  
Maurits K. Konings ◽  
Agnes van den Hoogen ◽  
Annemoon M.D.E. Timmerman

AbstractIntroductionInfusion therapy is challenging and dosing errors may occur due to physical phenomena related to the infusion hardware, despite the use of accurate syringe pumps. These errors typically occur after interventions, such as the exchange of a syringe. We aimed to characterize and quantify dosing errors due to a syringe exchange in relation to physical properties of infusion hardware.MethodsAn analytical simulation model was used to investigate dosing errors due to two different syringe exchange protocols (variations). Each protocol involved a fast syringe pump, containing a non-critical medication, and a slow syringe pump, containing a critical drug. The protocols were also reproduced inResultsThe syringe exchange of the slow pump resulted in an additional delay of up to 3536 seconds due to backflow. Syringe exchange of the fast pump resulted in an undiluted volume of critical drug (0.17 ml) accumulated in the infusion system, which may result in a dosing error rate of 2400 %. The quantity of the dosing errors are related to the syringe exchange duration; however, impact of infusion hardware properties is generally larger. Smaller syringes, catheters with larger diameters and less compliant infusion systems in general give rise to smaller dosing errors during a syringe exchange. If both lines are clamped, additional dosing errors can be prevented.ConclusionInfusion hardware has a substantial impact on the dosing errors during a syringe exchange. Clamping or blocking the infusion lines using, e. g. stopcocks, on all infusion lines during a syringe exchange is essential.


Author(s):  
Alexandrina Untaroiu ◽  
Amy L. Throckmorton ◽  
Houston G. Wood ◽  
Paul E. Allaire

A ventricular assist device (VAD) effectively relieves the workload from a native heart, which has been weakened by disease, and increases blood flow supplied to the body to maintain normal physiologic function. The device must be able to operate over a wide range of conditions. Designed to operate at a single, best-efficiency operating point, it must frequently perform at off-design conditions due to a fluctuating flow rate demanded by the human body and a time varying flow within the pump, due to the beating of the native heart. The design and optimization of a blood pump is a challenging and complex process. Pump design equations are used to estimate the initial dimensions of the pump regions. Computational fluid dynamics (CFD) analyses are then performed to optimize the blood flow path according to specific design criteria under steady flow conditions [1].


Author(s):  
Manju Lata ◽  
Mohammad Jamali

Purpose: This study aimed to document the present status of medicinal plants used to boost the immunity to combat Coronavirus. Materials and Methods: For the assessment and use of herbs during the Covid 19 pandemic, surveys were conducted in different villages of  Seraj block. The surveys were conducted during the spread of the pandemic from 2020 to 2021. Local people were interviewed and information on the utilization of local herbs during this pandemic was recorded. Information on parts used, the procedure of use, habit, habitat, etc. was also collected. Results: A total of 58 species of medicinal plants from 27 families and 42 genera were documented. Among them, the most dominant family was Rosaceae.  Most of the plants such as Morchella sp, Naustratium officinale,Taraxacum officinale ,Urtica dioica ,Allium sp,Withania foraminifera, Curcuma longa, Cannabis, Mentha, Ocimum sanctum are rich in antioxidants and have a wide range of medicinal values used to treat cough, cold, fever, and bronchitis. All these plants were used traditionally to boost immunity. Due to the covid -19 pandemic, the utilization of these herbal plants has increased many folds in the area. These medicinal plants should be made available to scientists to design clinical trials. Integration of this concept would certainly develop drug therapy in the near future. Conclusion: The study found that the use of medicinal plants has increased during COVID-19 and most of the respondents recommended medicinal plants to prevent COVID-19 and to boost immunity. More studies should be conducted to develop certain formulations.


2021 ◽  
Vol 17 (6) ◽  
pp. e1008364
Author(s):  
Andreas Bauer ◽  
Magdalena Prechová ◽  
Lena Fischer ◽  
Ingo Thievessen ◽  
Martin Gregor ◽  
...  

Cellular force generation and force transmission are of fundamental importance for numerous biological processes and can be studied with the methods of Traction Force Microscopy (TFM) and Monolayer Stress Microscopy. Traction Force Microscopy and Monolayer Stress Microscopy solve the inverse problem of reconstructing cell-matrix tractions and inter- and intra-cellular stresses from the measured cell force-induced deformations of an adhesive substrate with known elasticity. Although several laboratories have developed software for Traction Force Microscopy and Monolayer Stress Microscopy computations, there is currently no software package available that allows non-expert users to perform a full evaluation of such experiments. Here we present pyTFM, a tool to perform Traction Force Microscopy and Monolayer Stress Microscopy on cell patches and cell layers grown in a 2-dimensional environment. pyTFM was optimized for ease-of-use; it is open-source and well documented (hosted at https://pytfm.readthedocs.io/) including usage examples and explanations of the theoretical background. pyTFM can be used as a standalone Python package or as an add-on to the image annotation tool ClickPoints. In combination with the ClickPoints environment, pyTFM allows the user to set all necessary analysis parameters, select regions of interest, examine the input data and intermediary results, and calculate a wide range of parameters describing forces, stresses, and their distribution. In this work, we also thoroughly analyze the accuracy and performance of the Traction Force Microscopy and Monolayer Stress Microscopy algorithms of pyTFM using synthetic and experimental data from epithelial cell patches.


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