scholarly journals Immunity Boosting Medicinal Plants to Beat Covid -19 in Seraj Block of Mandi District, Himachal Pradesh

2021 ◽  
Vol 2 (4) ◽  
pp. 44-56
Author(s):  
Manju Lata ◽  
Mohammad Jamali
Keyword(s):  
Clinical Trials ◽  
Drug Therapy ◽  
Medicinal Plants ◽  
Curcuma Longa ◽  
Taraxacum Officinale ◽  
Urtica Dioica ◽  
Ocimum Sanctum ◽  
Wide Range ◽  
Herbal Plants ◽  
Near Future

Purpose: This study aimed to document the present status of medicinal plants used to boost the immunity to combat Coronavirus. Materials and Methods: For the assessment and use of herbs during the Covid 19 pandemic, surveys were conducted in different villages of  Seraj block. The surveys were conducted during the spread of the pandemic from 2020 to 2021. Local people were interviewed and information on the utilization of local herbs during this pandemic was recorded. Information on parts used, the procedure of use, habit, habitat, etc. was also collected. Results: A total of 58 species of medicinal plants from 27 families and 42 genera were documented. Among them, the most dominant family was Rosaceae.  Most of the plants such as Morchella sp, Naustratium officinale,Taraxacum officinale ,Urtica dioica ,Allium sp,Withania foraminifera, Curcuma longa, Cannabis, Mentha, Ocimum sanctum are rich in antioxidants and have a wide range of medicinal values used to treat cough, cold, fever, and bronchitis. All these plants were used traditionally to boost immunity. Due to the covid -19 pandemic, the utilization of these herbal plants has increased many folds in the area. These medicinal plants should be made available to scientists to design clinical trials. Integration of this concept would certainly develop drug therapy in the near future. Conclusion: The study found that the use of medicinal plants has increased during COVID-19 and most of the respondents recommended medicinal plants to prevent COVID-19 and to boost immunity. More studies should be conducted to develop certain formulations.

Antiviral and Immunity-modulating Natural Herbs in the Prevention of COVID-19

2021 ◽  
pp. 81-94
Author(s):  
Sonali S Gadge
Keyword(s):  
Immune System ◽  
Medicinal Plants ◽  
Nigella Sativa ◽  
Curcuma Longa ◽  
Antiviral Drug ◽  
Herbal Medicines ◽  
Echinacea Purpurea ◽  
Black Pepper ◽  
Tinospora Cordifolia ◽  
Ocimum Sanctum

The COVID-19 has spread all over the world and there is no single drug or medicine for the prevention and the treatment of this deadly disease. One can get prevention from this disease by boosting the immune system. Persons with weak immune system e.g. children, elder patients or patients with preexisting diseases affect rapidly due to coronavirus. This novel coronavirus attacks mainly on the person immunity. For the centuries the herbal medicinal plants have many beneficial effects against deadly viruses. Herbal medicines provide a rich resource for new antiviral drug development. These natural agents interact with the life cycle of virus such as virus entry, replication, assembly and release. In this review, the importance, immunomodulator, antiviral and pharmacological activities of some medicinal plants, namely, Allium Sativum, Zingiber Officinalis, Cinnamomum zeylanicum, Curcuma longa, Ocimum sanctum, Glycyrrhiza glabra, Ginseng, Black pepper, Emblica officinalis, Withania somnifera, Tinospora cordifolia, Echinacea purpurea, Azadirachta indica, Piper betel, Eugenia caryophyllata, Cinchona calisaya, Nigella sativa, Cuminum cyminum are highlighted. These medicinal plants have many phytoconstituents like alkaloids, glycosides, terpenoids, flavonoids, lactones, polysaccharides, volatile oils, tannins, resins, etc which are helpful for boosting immunity and will help in the prevention and in the management of COVID-19. Several types of research attempted to use herbal medicines against COVID-19.

scholarly journals Determination of carbohydrates in the herbal antidiabetic mixtures by GC-MC

2021 ◽  
Vol 71 (3) ◽  
pp. 429-443 ◽  
Author(s):  
Alona Savych ◽  
Svitlana Marchyshyn ◽  
Ivanna Milian
Keyword(s):  
Diabetes Mellitus ◽  
Zea Mays ◽  
Taraxacum Officinale ◽  
Urtica Dioica ◽  
Cichorium Intybus ◽  
Biologically Active ◽  
Mentha Piperita ◽  
Wide Range ◽  
Monomeric Composition

AbstractDue to the wide range of biologically active substances, the herbal mixtures can influence the development of diabetes mellitus and its complications. Carbohydrates attract particular attention due to their hypoglycemic, hypolipidemic, anticholesterolemic, antioxidant, antiinflammatory and detoxifying activities. The aim of this study was to investigate the content of carbohydrates through their monomeric composition in the herbal mixture samples: a) Urtica dioica leaf, Cichorium intybus roots, Rosa majalis fruits, Elymys repens rhizome, Taraxacum officinale roots, b) Arctium lappa roots, Elymys repens rhizome, Zea mays columns with stigmas, Helichrysum arenarium flowers, Rosa majalis fruits, c) Inula helenium rhizome with roots, Helichrysi arenarium flowers, Zea mays columns with stigmas, Origanum vulgare herb, Rosa majalis fruits, Taraxacum officinale roots, d) Cichorium intybus roots, Elymys repens rhizome, Helichrysum arenarium flowers, Rosa majalis fruits, Zea mays columns with stigmas and e) Urtica dioica leaf, Taraxacum officinale roots, Vaccinium myrtillus leaf, Rosa majalis fruits, Mentha piperita herb, which were used in Ukrainian folk medicine for the prevention and treatment of diabetes mellitus type 2.The carbohydrates were separated by gas chromatography-mass spectrometry after conversion into volatile aldononitrile acetate derivatives. The monomeric composition of polysaccharides was studied after their hydrolysis to form monosaccharides and poly-alcohols.Quantitative analyses of free carbohydrates showed that the predominant sugars were fructose, glucose and disaccharide – sucrose, in all samples. Concerning the determination of polysaccharide monomers after hydrolysis, glucose was the most abundant in all samples. The chromatographic study revealed a number of polyalcohols that are important for the treatment and prevention of progression of diabetes mellitus and its complications, namely, mannitol, pinitol and myo-inositol.

scholarly journals In vitro Antibacterial Effect of Medicinal Plants Against Multidrug Resistant Gram Negative Bacteria

2018 ◽  
Vol 5 ◽  
pp. 25-31
Author(s):  
Bishnu Thapa ◽  
Anjana Singh ◽  
Reshma Tuladhar
Keyword(s):  
Antibacterial Activity ◽  
Medicinal Plants ◽  
Multidrug Resistant ◽  
Diffusion Method ◽  
Ocimum Sanctum ◽  
Clinical Samples ◽  
Acorus Calamus ◽  
Gram Negative Bacteria ◽  
Gram Negative ◽  
Herbal Plants

Objectives: The aim of this work was to determine the antibacterial activity of methanol extract of herbal plants against the Multidrug resistant (MDR) Gram negative bacteria isolated from clinical samples. Methods: Gram negative bacteria isolated from various clinical samples were processed for antibiotic susceptibility test by modified Kirby-Bauer disc diffusion method and MDR bacteria were selected. Methanol extracts of six different medicinal plants Acorus calamus (bojho), Ocimum sanctum (tulsi), Azadirachta indica (neem), Cinnamomum tamala (tejpatta), Aloe vera and Zanthoxylum alatum (timur), were tested for antibacterial activity against the selected MDR bacteria by agar well diffusion method. Results: From clinical samples, 8 different MDR Gram negative bacteria isolated were Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Citrobacter spp., Proteus mirabilis, Proteus vulgaris, Acinetobacter spp. and Pseudomonas spp. with E. coli dominated the number. Out of six medicinal plants extracts, Z. alatum, C. tamala and Ocimum sanctum were found to be effective with zones of inhibition ranging from 9-13 mm. The medicinal plants with antibacterial activity can be an alternative source of medicine against MDR Gram negative bacteria. Conclusion: Several herbal plants extracts exhibit antibacterial activity against MDR Gram negative bacteria. Antibacterial activity of plant extracts can vary with type of plant and extraction methods. Thus, for optimal benefit of plant extract, an appropriate extraction method and use of purified product is essential.

Standardization of Phytomarker for Determining Immunomodulatory Activities in Ocimum sanctum and Curcuma longa

2020 ◽  
Vol 1 (28) ◽  
pp. 55-61
Keyword(s):  
Medicinal Plants ◽  
Curcuma Longa ◽  
Ocimum Sanctum ◽  
Therapeutic Activity ◽  
Herbal Drug ◽  
Plant Materials ◽  
Herbal Products ◽  
Treatment And Prevention ◽  
The World ◽  
Key Steps

Abstract-Medicinal plants have been used for centuriesandhavebecomepartofcomplementary medicine worldwide because of their health benefits. Some plants used directly in the treatment and prevention of infectious diseases or indirectly by stimulating the immune system. In recent years there is a great demand throughout the world to use herbal products in healthcare system. Plant materials and their products are becoming popular because of their widebiological activities. Standardization of herbal products is essential for their acceptance as remedies for various diseases and ailments. Marker based standardization is one of the widely accepted methods which is based on the analysis of phytochemical markers using HPTLC, HPLC etc.Identificationofmajoranduniquecompoundsinherbsasmarkersanddevelopment of analytical methodologies for monitoring them are the key steps involved in markerbasedstandardization.Markercompounds are chemically defined constituents of the herbal drug with or without therapeutic activity and can be used for the quality assurance of finished product. In nature, there are various medicinal plants which are used as immunomodulator agents. In this paper we standardize the phytomarkers of some selected plants which are very essential for our daily life.

scholarly journals Pharmacognostic Properties of Quisqualis indica Linn: Against Human Pathogenic Microorganisms: An Insight Review

2020 ◽  
pp. 87-103
Author(s):  
Braja Sundar Barik ◽  
Shritam Das ◽  
Tahziba Hussain
Keyword(s):  
Medicinal Plants ◽  
Large Scale ◽  
Aloe Vera ◽  
Ocimum Sanctum ◽  
Santalum Album ◽  
Pathogenic Microorganisms ◽  
Nepeta Cataria ◽  
Wide Range ◽  
Medicinal Properties ◽  
Anti Fungal

India has a large repository of medicinal plants that are used in traditional medical treatments. Several medicinal plants are useful for treating common ailments and some of the plants include Amla (Emblica cinalis), Ashoka (Saraca asoca), Aswagandha (Withania somnifera), Tulsi (Ocimum sanctum), Sarpa Gandha (Rauwolfia serpentina), Sandalwood (Santalum album), Indian birthwort (Aristolochia indica L.), Brahmi (Bacopa monnieri), Neem (Azardirchata indica), Vringraj (Eclipta alba), Grhit kumara (Aloe vera), Harida (Terminalia chebula) and Madhumalati (Quisqualis indica), Catnip (Nepeta cataria), Cayenne pepper (Capsicum annuum), Sage (Salvia officinalis); etc. Quisquails indica commonly known as the Madhu Malati, is a vine with red flower clusters and is found in abundance in India. It shows a wide range of remarkable medicinal properties. Over the last two decades, large scale research has been conducted to identify bio-active constituents of Quisqualis indica therapeutic prospects. This review summarizes the pharmacognostic properties of Quisqualis indica Linn. Against human pathogenic microorganisms. Several authors have reviewed the medicinal properties of Quisqualis indica Linn.but our review summarizes the anti-bacterial, anti-inflammatory, anti-oxidant, anti-pyretic, anti-helminthic, anti-diarrheal, anti-hyperglycemic, anti-microbial, anti-fungal and immuno-modulatory properties. It would be useful to students, academicians, microbiologists, as it reduces the need for detailed searching. It serves the purpose of quick reference.

scholarly journals Locomotive syndrome: from paradigms to clinical reality

2021 ◽  
Vol 93 (5) ◽  
Author(s):  
Marina V. Putilina ◽  
Natalia V. Teplova ◽  
Aleksander M. Lila ◽  
Nikolay V. Zagorodniy
Keyword(s):  
Drug Therapy ◽  
Behavioral Therapy ◽  
Balance Training ◽  
Clear Understanding ◽  
Locomotive Syndrome ◽  
Clinical Reality ◽  
Wide Range ◽  
Near Future ◽  
Functional Deterioration

Locomotive syndrome is an unsatisfactory condition of patients over 60 years of age who need or may require outside help in the near future due to functional deterioration of the musculoskeletal system, including pathology of bone tissue, joints, muscles and nervous tissue. In real clinical practice, one often has to deal with the following manifestations of locomotive syndrome: osteoarthritis, sarcopenia, balance disorders, chronic musculoskeletal pain. Today, there is a clear understanding that drug therapy should be long-term, include comprehensive support for muscle tissue, balance training, and mandatory cognitive-behavioral therapy. Maximum safety of long-term drug therapy can be ensured by the use of vital micronutrients, which include highly purified forms of chondroitin sulfate and glucosamine sulfate, which have a wide range of anti-inflammatory and regenerative effects.

scholarly journals Recent Advances of the Medicinal Plant Compound for Combating Pneumonia Disease: A Review

2021 ◽  
Vol 2 (6) ◽  
pp. 1-5
Author(s):  
Megha Patel ◽  
Bhavesh Sharma
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Infectious Diseases ◽  
Curcuma Longa ◽  
Antibacterial Properties ◽  
Punica Granatum ◽  
Primary Health Care System ◽  
Wide Range ◽  
Justicia Adhatoda ◽  
Punica Granatum L

Bacteria, influenza, parasites and fungi are pathogenic microorganisms that cause infectious diseases. Diseases can spread from one individual to another, either directly or indirectly. Infectious diseases are world’s second most common cause of death. Rainforest plants provide about quarter of drugs we need. Scientific research has been carried out on few medicinal plants, but only to small degree. Bacterial susceptibility to currently active antibiotics has necessitated discovery of new antibacterial agents. Several plants are widely used as herbal medicine for treatment of infectious diseases in rural and backward areas of India. This chapter looks over the publications on medicinal plants that are used to cure diseases like malaria, pneumonia. Traditional medicine is preferred primary health care system in many rural areas for variety of reasons, including its affordability and efficacy. The current study focused on existing medicinal plant literature, with ethnobotany, phytochemistry and pharmacology details being highlighted. All of examined plants showed potent action, supporting their conventional uses as well as their ability to cure common diseases. Curcuma longa L., Punica granatum L. and Justicia adhatoda L. were most widely used plant families for pneumonia therapy in research area (each with seven plants); of these, Curcuma longa L., Punica granatum L. and Justicia adhatoda L. had most inhibiting ability against Staphylococcus aureus and Streptococcus pneumoniae. Ascorbic acid, curcumin, vasicine, piperine, quercetin, myricetin and gallic acid have all been derived from these plants and are said to have antibacterial properties. Although Himalayan region has wide range of ethnomedicinal plants used to treat pneumonia, research on in-vivo activity, toxicology, and mechanism of action is minimal. As result, in order to produce novel antibacterial drugs from studied plant species, thorough study of these aspects is needed.

scholarly journals Systematic Review of Medicinal Plants Used for Treatment of Diabetes in Human Clinical Trials: An ASEAN Perspective

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Nazurah Hamizah Salleh ◽  
Ihsan Nazurah Zulkipli ◽  
Hartini Mohd Yasin ◽  
Fairuzeta Ja’afar ◽  
Norhayati Ahmad ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Blood Glucose ◽  
Medicinal Plants ◽  
Animal Studies ◽  
Curcuma Longa ◽  
Bitter Melon ◽  
Positive Effects ◽  
High Level ◽  
Data Collections

Traditionally, there are some medicinal plants believed to treat diabetes, as they have been proven in research studies to possess antidiabetic properties, such as improved insulin sensitivity and hypoglycemic activities, due to their high level of phenolic compounds, flavonoids, terpenoids, alkaloids, and glycosides. We conducted a systematic review to identify potential medicinal plants used during human clinical trials in the Association of Southeast Asian Nation (ASEAN) countries on prediabetic or type 2 diabetic individuals and to potentially identify any bioactive compounds involved in effectively treating symptoms of diabetes such as lowering of blood glucose. A total of 1209 reference titles were retrieved from four selected databases (Science Direct, Scopus, Springer Link, and PubMed) and only three met the inclusion criteria. Upon evaluation of the selected articles, four medicinal plants were identified: turmeric (Curcuma longa), garlic (Allium sativum L.), bitter melon (Momordica charantia), and Rosella flower (Hibiscus sabdariffa L.). Of these, only the bitter melon study did not show any significant change in the blood glucose of participants after intervention. This review demonstrates the limitations in published articles of human clinical trials for medicinal plants’ intervention for diabetes. Upon further investigations on the four identified medicinal plants included in the animal studies, the findings showed positive effects in the management of diabetes, such as hyperglycemia. Hence, further testing and standardization of the methods in the studies can be suggested for human clinical trials for reliable data collections such as methods of extract preparation, duration of intervention, and conditions set for the study design.

scholarly journals Potential Herbs as Eco-green Drugs for Aquaculture: A Review

2020 ◽  
Author(s):  
S. Bharathi ◽  
Cheryl Antony ◽  
A. Uma ◽  
C. Sudhan ◽  
J. Praveenraj ◽  
...  
Keyword(s):  
Curcuma Longa ◽  
Aloe Vera ◽  
Fish Farming ◽  
Zingiber Officinale ◽  
Floral Resources ◽  
Ocimum Sanctum ◽  
Cissus Quadrangularis ◽  
Herbal Plants ◽  
Medicinal Properties ◽  
Therapeutic Properties

Floral resources are abundant across the globe as it forms a key role in an ecological pyramid and enriched with a bunch of medicinal properties. Historical statue reveals various plants and its materials were used for treatments of different ailments and injuries and also used as nutraceuticals in humans and animals and also used for pest control in agriculture. The practice of using plants in aquaculture started in early 1990’s for various purposes by traditional farmers. Of late, due to overuse of fertilizers, antibiotics and other chemicals in aquaculture that created the environmental issues. As an alternative to chemicals and drugs, herbal based products can be used for eco and green aquaculture for safe and healthy fish productions. There are many potential herbal plants that have been identified and used in aquaculture and we focused on a few highly important herbal plants used in aquaculture. The potential herbal plants such as Aloe vera, Phyllanthus niruri, Azardirachta indica, Curcuma longa, Allium sativum, Ocimum sanctum, Zingiber officinale, Eclipta alba, Cissus quadrangularis, Acalypha indica could be used in fish farming. These herbal plants have versatile medicinal and therapeutic properties in fish, antioxidant, antifungal, antibacterial, antioxidant and immuno-stimulant. This review article gives information about the application of herbal plants in Aquaculture as a sustainable solution for safe and healthy fish productions.

scholarly journals COMPARE TO INTRALESIONAL THERAPY AND PHYTOCHEMICAL BASED SYSTEMIC DRUG THERAPY IN ORAL SUBMUCOUS FIBROSIS-CLINICOPHAMACOLOGICAL STUDY

2021 ◽  
pp. 1-3
Author(s):  
Swapnil Srivastava ◽  
Krishna Singh ◽  
Dharmendra Gupta ◽  
Monu Yadav
Keyword(s):  
Drug Therapy ◽  
Curcuma Longa ◽  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Burning Sensation ◽  
Tongue Protrusion ◽  
Intralesional Therapy ◽  
Wide Range ◽  
Submucous Fibrosis ◽  
Systemic Drug

Introduction: Oral sub-mucous fibrosis (OSMF) is characterized by abnormal collagen deposition. It is a precancerous disorder and transforms into a malignant tumor in 1.5–15% of all cases. Symptoms include submucous fibrosis, ulceration, xerostomia, a burning sensation restricted mouth opening and restricted tongue protrusion followed by oral mucosal blanching and uvla deviation. All of these greatly interfere with patient quality of life. Curcuma longa has been used for thousands of years as a remedy in the traditional Indian and folk medicine for the cure of a large variety of illnesses, such as inflammation, infectious diseases, and gastric, hepatic, and blood disorders. Curcumin is a major isolated polyphenol from the rhizome of turmeric (Curcuma longa). It has a wide range of pharmacological effects such as antioxidant, anti-inflammatory, antimicrobial, antitumor, and hepatoprotective activities. In our study curcumin used in OSMF as a systemic drug therapy and compare with intra-lesional therapy that’s widely used in OSMF Aims and objective: To check the efficacy of systemic drug therapy (curcumin longa) in OSMF, and compare with intra-lesional therapy (Dexamethasone with Hyaluronidase) in OSMF. Material and method 100 patients with clinically proven Oral Submucous Fibrosis were selected for the study and were randomly divided into 2 groups. The first group was treated with weekly Intralesional injection of 4 mg Dexamethasone & 1500 I.U Hyaluronidase and the second group by oral administration of two Curcumin tablets (Turmix 300 mg) per day for 4 months each. Improvement of burning sensation, interincisal distance, tongue protrusion and ulceration was evaluated on a weekly basis and compare to initial visit to end of treatment duration. Statistical analysis and Results: Burning sensation improved in both the groups from early to late stages. Complete Resolution of burning sensation was noted with Turmix early compare to intra-lesional therapy. The mean increase in inter-incisal distance or mouth opening was more compare to systemic drug therapy. The inter-incisal distance improved in both the groups gradually, but not more significant results at systemic drug therapy the end of both therapies. Tongue protrusion showed greater recovery at the end of last stmonth in group 1 when compared with group 2. Conclusion: Turmix is beneficial and effective in reducing burning sensation in early OSMF Patients so we can concluded on the basis of symptomatic relief systemic drug therapy with phyto-chemical based drug given better results compare to intralesional therapy.

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