scholarly journals Dependence of ζ-Potential upon Particle Size and Capillary Radius at Streaming Potential Study in Nonaqueous Media

1971 ◽  
Vol 44 (12) ◽  
pp. 3242-3245 ◽  
Author(s):  
Ayao Kitahara ◽  
Tadashi Fujii ◽  
Seiji Katano
Keyword(s):  
Particle Size ◽  
Streaming Potential ◽  
Nonaqueous Media ◽  
Ζ Potential ◽  
Capillary Radius ◽  
Potential Study

Chitosan nanoparticles for tamoxifen delivery and cytotoxicity to MCF-7 and Vero cells

2011 ◽  
Vol 83 (11) ◽  
pp. 2027-2040 ◽  
Author(s):  
Neralakere Ramanna Ravikumara ◽  
Basavaraj Madhusudhan
Keyword(s):  
Particle Size ◽  
Chitosan Nanoparticles ◽  
Vero Cells ◽  
In Vitro Cytotoxicity ◽  
Correlation Spectroscopy ◽  
Scanning Calorimetry ◽  
Ζ Potential ◽  
Human Red Blood Cells ◽  
Tamoxifen Citrate

In this study, tamoxifen citrate-loaded chitosan nanoparticles (tamoxcL-ChtNPs) and tamoxifen citrate-free chitosan nanoparticles (tamoxcF-ChtNPs) were prepared by an ionic gelation (IG) method. The physicochemical properties of the nanoparticles were analyzed for particle size, zeta (ζ) potential, and other characteristics using photon correlation spectroscopy (PCS), zeta phase analysis light scattering (PALS), scanning electron microscopy (SEM), Fourier transform infrared (FTIR), and differential scanning calorimetry (DSC). The variation in particle size was assessed by changing the concentration of chitosan, pentasodium tripolyphosphate (TPP), and the pH of the solution. The optimized tamoxcL-ChtNPs showed mean diameter of 187 nm, polydispersity of 0.125, and ζ-potential of +19.1 mV. The encapsulation efficiency (EE) of tamoxifen citrate (tamoxc) increased at higher concentrations, and release of tamoxc from the chitosan matrix displayed controlled biphasic behavior. Those tamoxcL-ChtNPs tested for chemosensitivity showed dose- and time-dependent antiproliferative activity of tamoxc. Further, tamoxcL-ChtNPs were found to be hemocompatible with human red blood cells (RBCs) and safe by in vitro cytotoxicity tests, suggesting that they offer promise as drug delivery systems in therapy.

Effect of clay colloids on the zeta potential of Fe/Al oxide-coated quartz: a streaming potential study

2016 ◽  
Vol 16 (12) ◽  
pp. 2676-2686 ◽  
Author(s):  
Zhong-yi Li ◽  
Ren-kou Xu ◽  
Jiu-yu Li ◽  
Zhi-neng Hong
Keyword(s):  
Zeta Potential ◽  
Streaming Potential ◽  
Potential Study ◽  
Al Oxide

scholarly journals Advancement of Measurement Techniques for Tunable Resistive Pulse Sensing

2021 ◽  
Author(s):  
◽  
Eva Weatherall
Keyword(s):  
Surface Charge ◽  
Pore Size ◽  
Applied Voltage ◽  
Particle Surface ◽  
Streaming Potential ◽  
Pore Surface ◽  
Size Distributions ◽  
Ζ Potential ◽  
Resistive Pulse ◽  
Tunable Resistive Pulse Sensing

<p>Tunable resistive pulse sensing (TRPS) is a particle-by-particle analysis technique combining the Coulter principle with size-tunable pores. TRPS can be used to characterize biological and synthetic particles 50 nm - 20 µm in diameter. Information is obtained from the resistive pulse signal, a transient change in ionic current observed when a particle passes through the pore. TRPS has been shown to provide excellent resolution and accuracy for measuring particle size and concentration as well as providing information about particle charge. TRPS is therefore applicable to many industrial and fundamental research areas involving aptamers, drug delivery particles, extracellular vesicles and other biological particle types. Advancement of this technology requires a better understanding of the technique, particularly in the area of particle surface charge measurement and this Thesis helps to provide that understanding.  In this work, firstly particle ζ-potential measurement using TRPS was investigated. A number of different measurement methods are presented and the uncertainties associated with each method are outlined. The ζ-potential for a variety of particles with different surface charges were measured in a range of electrolytes.  Particle ζ-potential measurements were then improved upon with the addition of streaming potential measurements to measure the pore surface charge. The ζ-potential of the pore surface, which makes a significant contribution to particle ζ-potential calculations, was measured using a set up which works alongside the qNano. Streaming potential measurements were also used to investigate changes in the pore surface charge following application of number of different chemical coatings. The volume of data collected and detail of analysis in this work (including uncertainties) is unprecedented in TRPS ζ potential measurements.  Biphasic pulses arising from the charge on the particles were investigated. The pulse is conventionally resistive, but biphasic pulses which include both resistive and conductive components are significant for less than 50 mM salt concentrations when measuring 200 nm particles. The experimental variables investigated include the concentration of the electrolyte, particle charge, pore size, applied voltage, and the direction of particlemotion. Conductive pulse size was seen to decrease with increasing electrolyte concentration and pore size and increase with applied voltage. A linear relationship was found between conductive pulse magnitude and particle surface group density. The influence of direction of motion on conductive pulses was consistent with concentration polarization of an ion selective pore. Biphasic pulses were also seen to affect conventional TRPS particle size measurements.  Finally, size distribution broadening due to varying particle trajectories was investigated. Pulse size distributions for monodisperse particles became broader when the pore size was increased and featured two distinct peaks. Relatively large pulses are produced by particles with trajectories passing near to the edge of the pore. Other experiments determined that pulse size distributions are independent of applied voltage but broaden with increasing pressure applied across the membrane.</p>

Zeta potential of particle bilayers on mica: A streaming potential study

2011 ◽  
Vol 360 (1) ◽  
pp. 195-203 ◽  
Author(s):  
Maria Zaucha ◽  
Zbigniew Adamczyk ◽  
Jakub Barbasz
Keyword(s):  
Zeta Potential ◽  
Streaming Potential ◽  
Potential Study

Colloidal characteristics of gelatin-treated clay: Intercalation, stability, wettability, and rheological properties

2021 ◽  
Vol 29 (9_suppl) ◽  
pp. S1361-S1370
Author(s):  
Xuwu Luo ◽  
Guancheng Jiang ◽  
Xinliang Li ◽  
Lili Yang
Keyword(s):  
Contact Angle ◽  
Particle Size ◽  
Rheological Properties ◽  
Water Contact Angle ◽  
X Ray Diffraction ◽  
Sem Images ◽  
Water Contact ◽  
Ζ Potential ◽  
And Behavior ◽  
Clay Intercalation

In this paper, sodium montmorillonite was modified with gelatin of different concentrations, and various colloidal characteristics of the gelatin-treated clays were measured and analyzed in detail. First, the influence of gelatin on the interlayer space of Mt layers was investigated by X-ray diffraction analysis. Moreover, the aggregation of Mt particles was examined using a combination of electron microscopy and particle size distribution experiments, while the variation of the electrical property of Mt was measured using ζ potential test. Gelatin of different concentrations can increase the particle size of Mt in different degrees. The addition of 4% gelatin could improve the ζ potential of Mt from −30.65 to −15.55 mV. The wettability change of modified Mt induced by the adsorption of gelatin was followed by measurements of water contact angle and observations of the morphology of Mt/gelatin membrane through SEM images. 4% gelatin could improve the water contact angle of Mt to 81.3°. Finally, the rheological properties of Mt/gelatin dispersion including shear viscosity and shear stress were measured using a stress-controlled rheometer. All of the results were consistent by showing that the overall colloidal characteristics and behavior of the gelatin-treated Mt strongly varied depending on the gelatin concentration used in the modification process. These results can provide a deep and comprehensive understanding of the colloidal properties of clay/gelatin systems and give important guidance for the performance design and improvement of Mt/gelatin composite materials. Furthermore, this study can also be expanded the application of gelatin and its composites to other fields.

Change of Multiple-Layered Phospholipid Vesicles Produced by Electrostatic Deposition of Polymers during Storage

2016 ◽  
Vol 12 (8) ◽  
pp. 763-771 ◽  
Author(s):  
Ji-Yeon Chun ◽  
Jochen Weiss ◽  
Monika Gibis ◽  
Mi-Jung Choi ◽  
Geun-Pyo Hong
Keyword(s):  
Particle Size ◽  
Layer By Layer ◽  
Ζ Potential ◽  
Electrostatic Deposition ◽  
Sedimentation Behavior ◽  
Physicochemical Stability ◽  
Release Study ◽  
Calcein Release ◽  
Liposome Surface ◽  
Positively Charged

Abstract In this study, 1 wt% lecithin (–), chitosan (+), and λ-carrageenan (–) were prepared to manufacture multiple-layered liposomes with optimal formulations developed in a previous study by using layer-by-layer electrostatic deposition. We observed their particle size, ζ-potential, sedimentation behavior, and microstructure for 6 weeks. Multiple-layered liposomes were quenched with calcein to evaluate stability in terms of factors such as encapsulation efficiency and released amount of calcein. The particle size of multi-layered liposomes increased with storage periods and the ζ-potential of multiple-layered liposomes gained a neutral charge. Interestingly, negatively charged layered liposomes were smaller than positively charged layered liposomes and showed a lower polydispersity index. Moreover, the ζ-potential did not apparently change compared to positively charged layered liposomes. For the calcein release study, multiple-layered liposomes significantly sustained quenched calcein more than that observed using non-layered liposomes. This study showed that it was possible to increase the thickness of the liposome surface and to manipulate its charge using chitosan and λ-carrageenan through electrostatic deposition. Results showed that manufacturing negatively charged multiple-layer (over 4-layer) liposomes with charged biopolymer improved the physicochemical stability of liposomes.

Mucoadhesive chitosan-dextran sulfate nanoparticles of acetazolamide for ocular hypertension

2016 ◽  
Vol 5 (5) ◽  
Author(s):  
Satish Manchanda ◽  
Pravat K. Sahoo ◽  
Dipak K. Majumdar
Keyword(s):  
Particle Size ◽  
Ocular Hypertension ◽  
Dextran Sulfate ◽  
Particle Morphology ◽  
Ionic Gelation ◽  
Potential Drug ◽  
Ζ Potential

AbstractChitosan-dextran sulfate nanoparticles of acetazolamide were formulated by using the ionic gelation technique, and evaluated for different attributes like particle size, ζ potential, drug entrapment, particle morphology,

Interaction between Penicillins and Human Serum Albumin:  A ζ-Potential Study

Langmuir ◽  
2000 ◽  
Vol 16 (17) ◽  
pp. 6795-6800 ◽  
Author(s):  
Pablo Taboada ◽  
Victor Mosquera ◽  
Juan M. Ruso ◽  
Felix Sarmiento ◽  
Malcolm N. Jones
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Ζ Potential ◽  
Potential Study
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