scholarly journals Preliminary Jaguar Health Study Findings: Changes In Cardiometabolic Risk Factors In College Freshmen

2021 ◽  
Vol 53 (8S) ◽  
pp. 62-62
Author(s):  
Robert J. Kowalsky ◽  
Sukho Lee ◽  
Soojin Yoo
Circulation ◽  
2016 ◽  
Vol 133 (suppl_1) ◽  
Author(s):  
Josiemer Mattei ◽  
Daniela Sotres-Alvarez ◽  
Marc Gellman ◽  
Sheila F Castaneda ◽  
Frank B Hu ◽  
...  

Introduction: C-reactive protein (CRP; a marker of inflammation) and the ankle-brachial index (ABI; a marker of peripheral artery disease (PAD)) are considered emerging risk factors for cardiovascular disease (CVD) in addition to traditional cardiometabolic markers. Results on the association of a healthy diet and these emerging risk factors have been inconsistent, and few studies have been conducted on Hispanics/Latinos, who present high prevalence of cardiometabolic risk factors. Hypothesis: We hypothesized that higher diet quality as measured with the Alternate Healthy Eating Index (AHEI; range 0-110: lowest to highest quality) would be associated with lower odds of having high-risk levels of CRP and of ABI, independently from cardiometabolic risk factors. Methods: Baseline data were analyzed from US-Hispanics/Latinos aged 18-74y without previously-diagnosed CVD participating in the population-based Hispanic Community Health Study/Study of Latinos cohort. There were 14,623 participants with complete CRP data, and 7,892 with ABI data (measured only for those aged ≥45y). Food and nutrients components of AHEI were assessed from two 24-hour recalls. High-risk CRP was defined as >3.0 mg/L, and high-risk ABI was defined as <0.90 or >1.40, with further categorization into PAD (<0.90) and arterial stiffness (>1.40). Results: Nearly 35% of Hispanics/Latinos had high-risk CRP levels and 6.3% had high-risk ABI (4.2% had PAD and 2.1% had arterial stiffness). After adjusting for demographic, socioeconomic, and lifestyle factors, as well as cardiometabolic risk factors (diabetes, hypertension, obesity, or dyslipidemia), the odds (95% confidence interval) of having high-risk ABI were 36% (5, 43%) lower for each 10-unit increase in AHEI (p=0.020). The association remained significant for PAD alone, albeit attenuated (p=0.046), but not for arterial stiffness (p=0.210). Each 10-unit increase in AHEI was associated with 21% (10, 31%) lower odds of high-risk CRP(p=0.0003) after similar adjustments. There were no significant interactions between AHEI and sex, background, smoking, or cardiometabolic risk factors for the associations with ABI. The association of AHEI with high-risk CRP was stronger for those with diabetes (0.68 (0.52, 0.89) vs. 0.82 (0.71, 0.94) without diabetes; p-interaction=0.0002) and with obesity (0.70 (0.58, 0.85) vs. 0.86 (0.73, 1.01) without obesity; p-interaction=0.0001). Conclusions: A higher diet quality is associated with lower inflammation and PAD among Hispanics/Latinos, independently from traditional cardiometabolic risk factors. Promoting a healthy overall diet may benefit with further lowering CVD-risk related to emerging factors in a population that already presents high prevalence of cardiometabolic markers.


2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Celine Heskey ◽  
Keiji Oda ◽  
Joan Sabate

Abstract Objectives To assess the relationship between habitual avocado intake, and cardiometabolic risk factors and metabolic syndrome (MetS). We hypothesized that regular avocado intake is associated with a lower occurrence of elevated blood glucose (BG), TG, blood pressure (BP), and waist circumference (WC), and/or decreased HDL-cholesterol (HDL-C). Methods This cross-sectional analysis was done on a random sample (n = ∼850) of subjects from the Adventist Health Study-2 cohort. Diet was assessed using a quantitative FFQ, which included an item for avocado/guacamole intake. Avocado intake (g/day) was calculated: f * s * n where f = the weighted frequency of avocado; s = the weighted portion size of avocado; and n = standard serving size (32 g) of avocado. FFQ data was also used to calculate total energy intake. Medication use, fasting BG, TG, HDL-C, BP, and WC were assessed during clinics. MetS was defined as follows: ≥3 of the diagnostic criteria defined by the Adult Treatment Panel III. Descriptive statistics including differences of means were analyzed. Logistic regression was used to determine the odds of metabolic syndrome for non-consumers (0 g/day; reference) versus consumers (>0 g/day; 51% of subjects) of avocado. Covariates were measured via a questionnaire: age, gender, race, education, energy intake, and dietary patterns. Results The odds for MetS for avocado consumers was non-significantly lower compared to nonconsumers: OR (95% CI) 0.87 (0.58, 1.30). Mean diastolic BP and WC were significantly lower among avocado consumers compared to nonconsumers. Mean HDL-C, TG, BG, and systolic BP did not differ between groups. Conclusions No relationship between habitual avocado intake and MetS has been found. However, there may be an inverse relationship between avocado intake and specific cardiometabolic risk factors: diastolic BP and WC. Funding Sources Hass Avocado Board, NIH, National Cancer Institute.


Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 2360-PUB
Author(s):  
ANGÉLICA M.M. VALENTE ◽  
BIANCA ALMEIDA-PITITTO ◽  
ALEXANDRE A. FERRARO ◽  
LUCIANA FOLCHETTI ◽  
ISIS T. SILVA ◽  
...  

2020 ◽  
Vol 38 (6) ◽  
pp. 682-691
Author(s):  
Caroline Brand ◽  
Clarice Maria De Lucena Martins ◽  
Vanilson Batista Lemes ◽  
Maria Luisa Félix Pessoa ◽  
Arieli Fernandes Dias ◽  
...  

Author(s):  
Sanem Kayhan ◽  
Nazli Gulsoy Kirnap ◽  
Mercan Tastemur

Abstract. Vitamin B12 deficiency may have indirect cardiovascular effects in addition to hematological and neuropsychiatric symptoms. It was shown that the monocyte count-to-high density lipoprotein cholesterol (HDL-C) ratio (MHR) is a novel cardiovascular marker. In this study, the aim was to evaluate whether MHR was high in patients with vitamin B12 deficiency and its relationship with cardiometabolic risk factors. The study included 128 patients diagnosed with vitamin B12 deficiency and 93 healthy controls. Patients with vitamin B12 deficiency had significantly higher systolic blood pressure (SBP), diastolic blood pressure (DBP), MHR, C-reactive protein (CRP) and uric acid levels compared with the controls (median 139 vs 115 mmHg, p < 0.001; 80 vs 70 mmHg, p < 0.001; 14.2 vs 9.5, p < 0.001; 10.2 vs 4 mg/dl p < 0.001; 6.68 vs 4.8 mg/dl, p < 0.001 respectively). The prevalence of left ventricular hypertrophy was higher in vitamin B12 deficiency group (43.8%) than the control group (8.6%) (p < 0.001). In vitamin B12 deficiency group, a positive correlation was detected between MHR and SBP, CRP and uric acid (p < 0.001 r:0.34, p < 0.001 r:0.30, p < 0.001 r:0.5, respectively) and a significant negative correlation was detected between MHR and T-CHOL, LDL, HDL and B12 (p < 0.001 r: −0.39, p < 0.001 r: −0.34, p < 0.001 r: −0.57, p < 0.04 r: −0.17, respectively). MHR was high in vitamin B12 deficiency group, and correlated with the cardiometabolic risk factors in this group, which were SBP, CRP, uric acid and HDL. In conclusion, MRH, which can be easily calculated in clinical practice, can be a useful marker to assess cardiovascular risk in patients with vitamin B12 deficiency.


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