Observations on the microbiology of urethritis in black South African men

2002 ◽  
Vol 13 (5) ◽  
pp. 323-325 ◽  
Author(s):  
D Taylor-Robinson ◽  
J S Jensen ◽  
G Fehler ◽  
F Radebe ◽  
R C Ballard
Keyword(s):  
Chlamydia Trachomatis ◽  
Neisseria Gonorrhoeae ◽  
South African ◽  
Mycoplasma Genitalium ◽  
Molecular Techniques ◽  
Black South African ◽  
Gonococcal Urethritis ◽  
Urine Specimens

The occurrence of Neisseria gonorrhoeae, Chlamydia trachomatis and Mycoplasma genitalium was determined by molecular techniques in urine specimens from 182 black South African men who had symptoms and/or overt signs of urethritis. Eighty-six (47.3%) of these men were infected with N. gonorrhoeae. There were 185 men without overt evidence of urethritis, 16 (8.6%) of whom were also infected with N. gonorrhoeae. Of the 96 men who had non-gonococcal urethritis, 14 (14.6%) were infected with C. trachomatis, 16 (16.7%) with M. genitalium and only one with both microorganisms. In comparison, 15 (8.9%) of 169 men without overt urethritis and without N. gonorrhoeae were infected with C. trachomatis and 15 (8.9%) with M. genitalium, proportions that were about half the size of those in the group with overt urethritis.

Urethritis

2020 ◽  
pp. 1606-1609
Author(s):  
Patrick Horner
Keyword(s):  
Chlamydia Trachomatis ◽  
Neisseria Gonorrhoeae ◽  
Partner Notification ◽  
Mycoplasma Genitalium ◽  
Urethral Discharge ◽  
Gonococcal Urethritis

Urethritis is defined as detectable urethral inflammation in the presence of symptoms or an observable urethral discharge. It is conventionally classified into gonococcal urethritis (GU, caused by Neisseria gonorrhoeae) and non-gonococcal urethritis (NGU, caused by Chlamydia trachomatis, Mycoplasma genitalium, and other causes, but with no known pathogen detected in over 30% of cases). Diagnosis is by urethral smear and microbiological investigations. Treatment with appropriate antibiotics should be given only to those with proven urethritis, and the diagnosis and its implications should be discussed with the patient. Partner notification is essential, not only to prevent re-infection but also to prevent onward transmission from partner(s) and the development of complications if left untreated.

scholarly journals Screening for asymptomatic Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium in medical students in Barcelona

2020 ◽  
Vol 2 ◽  
pp. 134-136
Author(s):  
Josep Riera-Monroig ◽  
Evelin L. Corbeto ◽  
Jordi Bosch ◽  
Irene Fuertes
Keyword(s):  
Medical Students ◽  
Chlamydia Trachomatis ◽  
Neisseria Gonorrhoeae ◽  
Sexual Partner ◽  
Medical Knowledge ◽  
Mycoplasma Genitalium ◽  
Sexually Transmitted ◽  
Vaginal Swabs ◽  
Positive Results ◽  
Urine Specimens

Objectives: No previous studies had been performed on asymptomatic sexually transmitted infections (STIs) in Spanish university students. Therefore, the aim of the study was to determine the prevalence of Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT), and Mycoplasma genitalium (MG) in this group. Material and Methods: All medical students were invited to participate in the study between September 2017 and June 2019. First-void urine specimens were collected from men and vaginal swabs from women. Results: Four females had positive results. The prevalence of CT and MG in women was 4.0% and 2.4%. All individuals with positive results had stable partners. CT infection was associated with having stable and sporadic sexual partner in the previous year. The frequency of positive results was higher in those women who had sought an app-based sexual partner. Conclusion: The prevalence of asymptomatic STI in medical students was similar (rather than lower) to that in same age individuals in the area. Medical knowledge might not protect from STI acquisition.

scholarly journals Prevalence of urogenital, anal, and pharyngeal infections with Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium: a cross-sectional study in Reunion island

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
A. Calas ◽  
N. Zemali ◽  
G. Camuset ◽  
J. Jaubert ◽  
R. Manaquin ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Neisseria Gonorrhoeae ◽  
Mycoplasma Genitalium ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Sexually Transmitted ◽  
Urogenital Infection ◽  
High Prevalence

Abstract Background Recommendations for sexually transmitted infection (STI) screening vary significantly across countries. This study evaluated the prevalence of urogenital and extragenital infections with Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Mycoplasma genitalium (MG) in patients visiting a French STI clinic in the Indian Ocean region to determine whether current STI screening practices should be updated. Methods This cross-sectional study examined all patients who visited the STI clinic between 2014 and 2015. Triplex polymerase chain reaction screening for CT, NG, and MG was performed on urine, vaginal, pharyngeal, and anal specimens (FTD Urethritis Basic Kit, Fast Track Diagnostics, Luxembourg). Results Of the 851 patients enrolled in the study, 367 were women (367/851, 43.2%) and 484 were men (484/851, 56.0%). Overall, 826 urogenital specimens (826/851, 97.1%), 606 pharyngeal specimens (606/851, 71.2%), and 127 anal specimens (127/851, 14.9%) were taken from enrolled patients. The prevalence of urogenital CT and MG was high in women ≤25 years (19/186, 10.21%; 5/186, 2.69%) and in men who have sex with women ≤30 years (16/212, 7.54%; 5/212, 2.36%). Among patients with urogenital CT infection, 13.7% (7/51) had urethritis. All patients with urogenital MG infection were asymptomatic. Men who have sex with men had a high prevalence of pharyngeal CT (2/45, 4.44%) and NG (3/44, 6.81%) and a high prevalence of anal CT (2/27, 7.41%), NG (2/27, 7.40%), and MG (1/27, 3.70%). After excluding patients with concomitant urogenital infection, extragenital infections with at least 1 of the 3 pathogens were found in 20 swabs (20/91, 21.9%) taken from 16 patients (16/81, 19.7%), all of them asymptomatic. Conclusions Routine multisite screening for CT, NG, and MG should be performed to mitigate the transmission of STIs in high-risk sexually active populations.

Non-gonococcal urethritis and mucopurulent cervicitis

2019 ◽  
pp. 161-168
Keyword(s):  
Antibiotic Resistance ◽  
Chlamydia Trachomatis ◽  
Clinical Features ◽  
Mycoplasma Genitalium ◽  
Common Cause ◽  
Urethral Discharge ◽  
Separate Section ◽  
Diagnosis And Management ◽  
Gonococcal Urethritis

Non-gonococcal urethritis (NGU) is caused by Chlamydia trachomatis in 11–50% of cases, but Mycoplasma genitalium is being increasingly recognized as a common cause. Mycoplasma genitalium is not as well understood, and experience with treatment is limited; however, antibiotic resistance is already a problem. Asymptomatic in up to 20% of men, symptoms include dysuria and urethral discharge. Mucopurulent cervicitis is the female equivalent, but is less well defined. This chapter describes the aetiology, clinical features, complications, and investigations and management of NGU, and mucopurulent cervicitis. Management of recurrent and persistent urethritis is also covered, including a separate section for diagnosis and management of Mycoplasma genitalium.

Prevalence of Mycoplasma genitalium in men with gonococcal urethritis

1996 ◽  
Vol 7 (6) ◽  
pp. 443-444 ◽  
Author(s):  
M Uno ◽  
T Deguchi ◽  
H Komeda ◽  
M Yasuda ◽  
M Tamaki ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Chlamydia Trachomatis ◽  
Enzyme Immunoassay ◽  
Mycoplasma Genitalium ◽  
Chain Reaction ◽  
Gonococcal Urethritis ◽  
Japanese Male ◽  
Male Patients ◽  
Polymerase Chain

A significant association of Mycoplasma genitalium with non-gonococcal urethritis has been reported, but the prevalence of this mycoplasma in men with gonococcal urethritis has not been so well studied. In this study, we examined urethral swab specimens from 45 Japanese male patients with gonococcal urethritis for the presence of M. genitalium by using a polymerase chain reaction-based assay. We also sought Chlamydia trachomatis by an enzyme immunoassay Chlamydiazyme . Of the 45 specimens, 2 4.4 were positive for the mycoplasma and 12 26.7 were positive for C. trachomatis. The findings suggest that M. genitalium may be a cause not only of non-gonococcal urethritis but also of postgonococcal urethritis.

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