Urethritis

2020 ◽  
pp. 1606-1609
Author(s):  
Patrick Horner

Urethritis is defined as detectable urethral inflammation in the presence of symptoms or an observable urethral discharge. It is conventionally classified into gonococcal urethritis (GU, caused by Neisseria gonorrhoeae) and non-gonococcal urethritis (NGU, caused by Chlamydia trachomatis, Mycoplasma genitalium, and other causes, but with no known pathogen detected in over 30% of cases). Diagnosis is by urethral smear and microbiological investigations. Treatment with appropriate antibiotics should be given only to those with proven urethritis, and the diagnosis and its implications should be discussed with the patient. Partner notification is essential, not only to prevent re-infection but also to prevent onward transmission from partner(s) and the development of complications if left untreated.

Non-gonococcal urethritis (NGU) is caused by Chlamydia trachomatis in 11–50% of cases, but Mycoplasma genitalium is being increasingly recognized as a common cause. Mycoplasma genitalium is not as well understood, and experience with treatment is limited; however, antibiotic resistance is already a problem. Asymptomatic in up to 20% of men, symptoms include dysuria and urethral discharge. Mucopurulent cervicitis is the female equivalent, but is less well defined. This chapter describes the aetiology, clinical features, complications, and investigations and management of NGU, and mucopurulent cervicitis. Management of recurrent and persistent urethritis is also covered, including a separate section for diagnosis and management of Mycoplasma genitalium.


2002 ◽  
Vol 13 (5) ◽  
pp. 323-325 ◽  
Author(s):  
D Taylor-Robinson ◽  
J S Jensen ◽  
G Fehler ◽  
F Radebe ◽  
R C Ballard

The occurrence of Neisseria gonorrhoeae, Chlamydia trachomatis and Mycoplasma genitalium was determined by molecular techniques in urine specimens from 182 black South African men who had symptoms and/or overt signs of urethritis. Eighty-six (47.3%) of these men were infected with N. gonorrhoeae. There were 185 men without overt evidence of urethritis, 16 (8.6%) of whom were also infected with N. gonorrhoeae. Of the 96 men who had non-gonococcal urethritis, 14 (14.6%) were infected with C. trachomatis, 16 (16.7%) with M. genitalium and only one with both microorganisms. In comparison, 15 (8.9%) of 169 men without overt urethritis and without N. gonorrhoeae were infected with C. trachomatis and 15 (8.9%) with M. genitalium, proportions that were about half the size of those in the group with overt urethritis.


e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Jonna Palenewen ◽  
Ferra O. Mawu ◽  
Nurdjanah J. Niode

Abstract: Gonococcal urethritis (GU) is an inflammation of the urethra caused by Gram negative bacteria Neisseria gonorrhoeae associated with complaints of itching and burning sensation, pain during urination, mucopurulent urethral discharge from the tip of the urethra which sometimes bleeds, and pollakiuria. Non-gonococcal urethritis (NGU) is an inflammation of the urethra caused by Gram-negative bacterium Chlamydia trachomatis which is transmitted through sexual contact. Symptoms include mild dysuria, an uneasy feeling in the urethra, pollakiuria, and seropurulent urethral discharge. This study aimed to determine the profile of gonococcal urethritis and non-gonococcal urethritis in the Dermatovenereology Clinic of Prof. Dr. R. D. Kandou Hospital Manado from January-December 2013. This was a retrospective descriptive study based on the type of disease (GU or NGU), age, occupation, and sexual orientation. The results showed 204 cases of sexual transmitted infections (STIs). There were 27 cases of GU (6 %) and 10 cases of NGU (2 %). Most of GU and NGU patients were 25-44 years (17,46%) with private employment (17,47 %), and sexual orientation to heterosexual (37,10 %). Keywords: gonococcal urethritis, non-gonococcal urethritisAbstrak: Uretritis gonokokus (UG) ialah peradangan uretra disebabkan oleh bakteri Gram negatif Neisseria gonorrhoeae dengan keluhan gatal, panas, nyeri saat berkemih, dapat disertai keluar duh tubuh mukopurulen dari ujung uretra yang kadang mengeluarkan darah, dan polakisuria. Uretritis non gonokokus (UNG) ialah peradangan uretra disebabkan oleh bakteri Gram negatif Chlamydia trachomatis yang ditularkan melalui kontak seksual. Gejala berupa disuria ringan, perasaan tidak enak di uretra, polakisuria, dan keluarnya duh tubuh seropurulen. Penelitian ini bertujuan untuk mengetahui profil uretritis gonokokus dan non gonokokus di Poliklinik Kulit dan Kelamin RSUP Prof Dr. R. D. Kandou Manado periode Januari-Desember 2013. Jenis penelitian ini deskriptif retrospektif berdasarkan jenis penyakit (UG atau UNG), usia, pekerjaan, dan orientasi seksual. Hasil penelitian menunjukkan dari 204 kasus infeksi menular seksual (IMS) terdapat 27 kasus UG (6%) dan 10 kasus UNG (2%). Penderita terbanyak pada kelompok usia 25-44 tahun (17,46%), dengan pekerjaan swasta (17,47%), serta orientasi seksual dengan heteroseksual (37,100%).Kata kunci: uteritis gonokokus, uretritis non gonokokus


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
A. Calas ◽  
N. Zemali ◽  
G. Camuset ◽  
J. Jaubert ◽  
R. Manaquin ◽  
...  

Abstract Background Recommendations for sexually transmitted infection (STI) screening vary significantly across countries. This study evaluated the prevalence of urogenital and extragenital infections with Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Mycoplasma genitalium (MG) in patients visiting a French STI clinic in the Indian Ocean region to determine whether current STI screening practices should be updated. Methods This cross-sectional study examined all patients who visited the STI clinic between 2014 and 2015. Triplex polymerase chain reaction screening for CT, NG, and MG was performed on urine, vaginal, pharyngeal, and anal specimens (FTD Urethritis Basic Kit, Fast Track Diagnostics, Luxembourg). Results Of the 851 patients enrolled in the study, 367 were women (367/851, 43.2%) and 484 were men (484/851, 56.0%). Overall, 826 urogenital specimens (826/851, 97.1%), 606 pharyngeal specimens (606/851, 71.2%), and 127 anal specimens (127/851, 14.9%) were taken from enrolled patients. The prevalence of urogenital CT and MG was high in women ≤25 years (19/186, 10.21%; 5/186, 2.69%) and in men who have sex with women ≤30 years (16/212, 7.54%; 5/212, 2.36%). Among patients with urogenital CT infection, 13.7% (7/51) had urethritis. All patients with urogenital MG infection were asymptomatic. Men who have sex with men had a high prevalence of pharyngeal CT (2/45, 4.44%) and NG (3/44, 6.81%) and a high prevalence of anal CT (2/27, 7.41%), NG (2/27, 7.40%), and MG (1/27, 3.70%). After excluding patients with concomitant urogenital infection, extragenital infections with at least 1 of the 3 pathogens were found in 20 swabs (20/91, 21.9%) taken from 16 patients (16/81, 19.7%), all of them asymptomatic. Conclusions Routine multisite screening for CT, NG, and MG should be performed to mitigate the transmission of STIs in high-risk sexually active populations.


1996 ◽  
Vol 7 (6) ◽  
pp. 443-444 ◽  
Author(s):  
M Uno ◽  
T Deguchi ◽  
H Komeda ◽  
M Yasuda ◽  
M Tamaki ◽  
...  

A significant association of Mycoplasma genitalium with non-gonococcal urethritis has been reported, but the prevalence of this mycoplasma in men with gonococcal urethritis has not been so well studied. In this study, we examined urethral swab specimens from 45 Japanese male patients with gonococcal urethritis for the presence of M. genitalium by using a polymerase chain reaction-based assay. We also sought Chlamydia trachomatis by an enzyme immunoassay Chlamydiazyme . Of the 45 specimens, 2 4.4 were positive for the mycoplasma and 12 26.7 were positive for C. trachomatis. The findings suggest that M. genitalium may be a cause not only of non-gonococcal urethritis but also of postgonococcal urethritis.


2015 ◽  
Vol 54 (1) ◽  
pp. 200-203 ◽  
Author(s):  
Jan Henk Dubbink ◽  
Dewi J. de Waaij ◽  
Myrte Bos ◽  
Lisette van der Eem ◽  
Cécile Bébéar ◽  
...  

We analyzed data of 263 women with at least one genital or anorectal sexually transmitted infection from a cross-sectional study conducted in rural South Africa. We provide new insights concerning the concurrence ofChlamydia trachomatis,Neisseria gonorrhoeae,Mycoplasma genitalium, andTrichomonas vaginalisinfections as well as the characteristics of bacterial loads.


Sign in / Sign up

Export Citation Format

Share Document