Research Progress on the Relationship between Cerebral Infarction and Intestinal Microbiome

2021 ◽  
Vol 11 (07) ◽  
pp. 3083-3090
Author(s):  
潇 杨
Keyword(s):  
Cerebral Infarction ◽  
Intestinal Microbiome ◽  
Research Progress ◽  
The Relationship

scholarly journals Research Progress of Desertification and Its Prevention in Mongolia

2021 ◽  
Vol 13 (12) ◽  
pp. 6861
Author(s):  
Xiya Liang ◽  
Pengfei Li ◽  
Juanle Wang ◽  
Faith Ka Shun Chan ◽  
Chuluun Togtokh ◽  
...  
Keyword(s):  
Model Development ◽  
Mitigation Strategies ◽  
Research Progress ◽  
Prevention Measures ◽  
Interdisciplinary Approaches ◽  
The World ◽  
Impacting Factors ◽  
Decoupling Analysis ◽  
And Control ◽  
The Relationship

Mongolia is a globally crucial region that has been suffering from land desertification. However, current understanding on Mongolia’s desertification is limited, constraining the desertification control and sustainable development in Mongolia and even other parts of the world. This paper studied spatiotemporal patterns, driving factors, mitigation strategies, and research methods of desertification in Mongolia through an extensive review of literature. Results showed that: (i) remote sensing monitoring of desertification in Mongolia has been subject to a relatively low spatial resolution and considerable time delay, and thus high-resolution and timely data are needed to perform a more precise and timely study; (ii) the contribution of desertification impacting factors has not been quantitatively assessed, and a decoupling analysis is desirable to quantify the contribution of factors in different regions of Mongolia; (iii) existing desertification prevention measures should be strengthened in the future. In particular, the relationship between grassland changes and husbandry development needs to be considered during the development of desertification prevention measures; (iv) the multi-method study (particularly interdisciplinary approaches) and desertification model development should be enhanced to facilitate an in-depth desertification research in Mongolia. This study provides a useful reference for desertification research and control in Mongolia and other regions of the world.

Research progress in predicting DNA methylation modifications and the relation with human diseases

2021 ◽  
Vol 28 ◽  
Author(s):  
Chunyan Ao ◽  
Lin Gao ◽  
Liang Yu
Keyword(s):  
Dna Methylation ◽  
Eukaryotic Cell ◽  
Machine Learning Algorithms ◽  
Research Progress ◽  
Epigenetic Mechanisms ◽  
Biological Processes ◽  
Prediction Tools ◽  
Transformation Mechanisms ◽  
The Relationship ◽  
Treatment And Diagnosis

: DNA methylation is an important mode of regulation in epigenetic mechanisms, and it is one of the research foci in the field of epigenetics. DNA methylation modification affects a series of biological processes, such as eukaryotic cell growth, differentiation and transformation mechanisms, by regulating gene expression. In this review, we systematically summarized the DNA methylation databases, prediction tools for DNA methylation modification, machine learning algorithms for predicting DNA methylation modification, and the relationship between DNA methylation modification and diseases such as hypertension, Alzheimer's disease, diabetic nephropathy, and cancer. An in-depth understanding of DNA methylation mechanisms can promote accurate prediction of DNA methylation modifications and the treatment and diagnosis of related diseases.

scholarly journals Intestinal microbiome composition and its relation to joint pain and inflammation

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Cindy G. Boer ◽  
Djawad Radjabzadeh ◽  
Carolina Medina-Gomez ◽  
Sanzhima Garmaeva ◽  
Dieuwke Schiphof ◽  
...  
Keyword(s):  
Knee Pain ◽  
Joint Pain ◽  
Large Population ◽  
Absolute Quantification ◽  
Population Based ◽  
Intestinal Microbiome ◽  
Gastrointestinal Microbiome ◽  
Microbiome Composition ◽  
Show Evidence ◽  
The Relationship

Abstract Macrophage-mediated inflammation is thought to have a causal role in osteoarthritis-related pain and severity, and has been suggested to be triggered by endotoxins produced by the gastrointestinal microbiome. Here we investigate the relationship between joint pain and the gastrointestinal microbiome composition, and osteoarthritis-related knee pain in the Rotterdam Study; a large population based cohort study. We show that abundance of Streptococcus species is associated with increased knee pain, which we validate by absolute quantification of Streptococcus species. In addition, we replicate these results in 867 Caucasian adults of the Lifelines-DEEP study. Finally we show evidence that this association is driven by local inflammation in the knee joint. Our results indicate the microbiome is a possible therapeutic target for osteoarthritis-related knee pain.

Research Progress on Cellulose Degradation Bacteria Isolation and Utilization

2013 ◽  
Vol 448-453 ◽  
pp. 1612-1615
Author(s):  
Cheng Jiao Xu ◽  
Ai Jie Wang ◽  
Lin Na Chen ◽  
Guang Li Cao ◽  
Nan Qi Ren
Keyword(s):  
Anaerobic Condition ◽  
Energy Recovery ◽  
Cellulose Degradation ◽  
Mutual Effect ◽  
Cellulose Hydrolysis ◽  
Product Recovery ◽  
Research Progress ◽  
The Relationship

Cellulose is regarded as a kind of biomass with high quantity, the proper utilization could realize energy recovery and high-value product recovery. Cellulose degradation is of great importance for its utilization. This article introduced the isolation, characteristic and the mutual effect of compound cellulose degradation bacteria, the composition, the effect and mechanism for cellulose hydrolysis were also introduced. Rumen microbial were taken as example for its utilization in cellulose degradation. The relationship between anaerobic and aerobic were discussed to evaluate their mutual effect. It is proved that the aerobic microorganism could help to provide the anaerobic condition for the bacteria, while the anaerobic could reduce the product inhibitor effect.

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