Statistical modeling of significant diagnostic methods used in the treatment ofprimary forms of inflammatory periodontal diseases

10.12737/6674 ◽  
2014 ◽  
Vol 8 (1) ◽  
pp. 0-0
Author(s):  
Коровкина ◽  
A. Korovkina

In the article the ground of choice of meaningful methods of diagnostics is carried out on the basis of statistical analysis of data got during realization of photo-radiotherapy of initial forms of inflammatory diseases of paradontium. For this purpose inspection was conducted in 100 patients with gingivitis of easy and middle degree, periodontitis of easy degree by means of an offer algorithm of diagnostics – clinical and laboratory me-thods. The clinical methods were indexes, stomatoscopy and the laboratory method was the laser Doppler flow-metry. All patients were divided into 2 groups: basic (50 patients), which was applied photo-radiotherapy using a device Uzor-А-2К by power 18 W; and control (50 patients) to them medical treatment was recommended. Sta-tistical analysis of data, obtained in the study, was performed using SAS 9.3. and Microsoft Office 2010 - analysis of contingency tables and logistic regression.Significant diagnostic methods when conducting contin-gency tables were stomatoscope and the CPITN index. Laser Doppler flowmetry and significant parameters of microcirculation were determined using the method of logical regression. This is testified to optimally proposed algorithm for diagnosis of early forms of inflammatory periodontal diseases.

2020 ◽  
Vol 76 (4) ◽  
pp. 73-76
Author(s):  
E.N. Yarygina ◽  
◽  
A.E. Kriventsev ◽  
L.V. Vardanyan ◽  
R.R. Vezirov ◽  
...  

In dental practice, patients with periodontal diseases are quite common. Therefore, to improve the effectiveness of treatment tactics, this article discusses the basic principles of surgical treatment of periodontal pockets using the M-Chip nanomatrix. Laser Doppler flowmetry and index assessment of periodontal tissues were used as diagnostic methods for checking the results.


2006 ◽  
Vol 17 (3) ◽  
pp. 219-222 ◽  
Author(s):  
Hakan Develioglu ◽  
Bülent Kesim ◽  
Aykut Tuncel

The purposes of this study were to compare the gingival blood flow (GBF) in test sites (teeth retaining fixed partial dentures) and control sites (contralateral natural teeth) and investigate whether there is any relationship between clinical indices and GBF values. Twelve healthy subjects (6 females and 6 males) aged 20 to 54 years were enrolled this study. The GBF was measured from the middle point of the marginal gingiva in the test and control sites using laser Doppler flowmetry (LDF). Additionally, plaque index, gingival index and probing depth measurements were recorded. Statistically significant difference (p<0.05) was found between the test and control sites for marginal GBF. In contrast, no significant difference (p>0.05) was found between test and control sites with respect to the clinical indices, except for plaque index. The findings of this study suggest that there is a significant relation between resin-bonded fixed partial dentures with margins located subgingivally and marginal GBF. Clinical indices are helpful to collect information about the clinical health status of gingival tissues, but GBF is a good tool to measure gingival tissue blood flow and assess periodontal health. In conclusion, laser Doppler flowmetry can be used together with clinical indices to evaluate the marginal gingival health.


2021 ◽  
Vol 11 (8) ◽  
pp. 801
Author(s):  
Ani Belcheva ◽  
Maria Shindova ◽  
Reem Hanna

Aim: This study aimed to evaluate the efficacy of laser Doppler flowmetry (LDF) in determining the changes in the pulpal blood flow (PBF) during post-traumatic period of the traumatised permanent teeth. Methods: 88 teeth of 44 patients (mean age 10.30 ± 2.38) were recruited according to the eligibility criteria and divided into two groups: test group (44 traumatised teeth) and control group (44 sound and healthy teeth). The measurement of PBF was performed, using a LDF monitor. Results: The analysis of the LDF outcomes in function of diagnosis indicated that the measurements of the traumatised teeth were significantly higher than those of non-traumatised teeth (p ˂ 0.05). Conclusions: LDF application provides dentists with fundamental benefits in terms of an early and precise investigation of PBF. In addition, LDF is a useful monitoring tool for revascularization of traumatised teeth and reliable objective diagnostic indicator of pulp vitality. Trial registration: ClinicalTrials.gov (Registration number: NCT04967456).


2021 ◽  
Vol 10 (2) ◽  
pp. 18-24
Author(s):  
P. V. Vasilev ◽  
N. P. Erofeev ◽  
A. N. Shishkin

The article contains the results of a study of two different methods for calculating the spectral parameters of laser Doppler flowmetry in patients with diabetic microangiopathy caused by type 2 diabetes mellitus (main group) and those with excluded diabetes mellitus (control group). Spectral indices were calculated using either average or maximum amplitudes of the frequency ranges. When comparing the contribution of respiratory and pulse fluxmotions using average amplitudes, there were significant (p < 0.05) differences between the main and control groups. On the contrary, when using the maximum amplitudes, no significant differences were noted (p > 0.05). Also, significant correlations were found between the contributions of respiratory and pulse fluxmotions and the estimated glomerular filtration rate in the main group, using both calculation methods. These studies indicate the feasibility of using a technique based on the analysis of average amplitudes to increase the specificity of laser Doppler flowmetry as a method for diagnosing diabetic microangiopathy.


World Science ◽  
2019 ◽  
Vol 2 (9(49)) ◽  
pp. 9-14
Author(s):  
Борисенко А. В. ◽  
Ватанха Т. В. ◽  
Мостовий С. Є.

Urgency. Periodontal disease is the most common human diseases. As etiologic factors among systemic diseases an important role is played by disorders of the sexual system, especially in women. Due to the use of hormonal contraceptives with estrogens, they have developed periodontal disease. For the treatment of these lesions a special method of treatment is proposed. Laser Doppler flowmetry was used to evaluate the effectiveness of the treatment.Aim: To determine the clinical effectiveness of the proposed method of complex treatment of periodontal diseases in women taking hormonal contraceptives for pregnancy planning, by estimating the blood flow in periodontal microvessels by laser Doppler flowmetry.Materials and methods. Clinical studies performed on a group of 130 women taking hormonal contraceptives for pregnancy planning with periodontal diseases. Patients were conducted a comprehensive examination of periodontal tissue before treatment and after treatment. To evaluate the clinical efficacy of treatment used Schiller-Pisarev test 1962), the index of PMA by C.Parma (1961), hygienic index by Green J.C., Vermillion J.R. (1964). Laser Doppler Flowmetry was used to evaluate the treatment efficacy.Results. As a result of the study it was found that the use of the proposed method of treatment with the drug "Normoven" can more effectively suppress dystrophic-inflammatory process in the tissues of the periodontium. This confirms ин the reduction of periodontal indices, improvement of oral hygiene, improvement of microcirculation in the tissues of periodontal patients.Conclusions. The application of the proposed treatment method increases the level of microcirculation in the gums of women with periodontal diseases who have taken oral contraceptives for the purpose of pregnancy planning.


2019 ◽  
Vol 9 (2) ◽  
pp. 217 ◽  
Author(s):  
Ksenia Kandurova ◽  
Viktor Dremin ◽  
Evgeny Zherebtsov ◽  
Elena Potapova ◽  
Alexander Alyanov ◽  
...  

The paper presents the results of experimental measurements of endogenous fluorescence and blood perfusion in patients with pathology of the organs of hepatopancreatoduodenal area in vivo. A custom setup combining channels for fluorescence spectroscopy (excitation wavelengths of 365 nm and 450 nm) and laser Doppler flowmetry (1064 nm) with fibre optical probe for nondestructive laparoscopic measurements has been developed and applied during minimally invasive operation procedure. Preliminary measurements with two aforementioned channels have been performed at specified excitation wavelengths. The possibility of obtaining fluorescence spectra and laser Doppler flowmetry signals in vivo during minimally invasive interventions was shown. Obtained data show perspectives of further research on technical and methodological development of optical diagnostic methods for minimally invasive surgery. The obtained results can be used to provide a deeper understanding of pathological processes influence on optical properties of abdominal organs tissues, which will ultimately help surgeons to determine the state of vitality in tissues and mucous membranes directly during the process of surgical intervention.


VASA ◽  
2005 ◽  
Vol 34 (4) ◽  
pp. 243-249 ◽  
Author(s):  
Drinda ◽  
Neumann ◽  
Pöhlmann ◽  
Vogelsang ◽  
Stein ◽  
...  

Background: Prostanoids are used in the treatment of Raynaud’s phenomenon and acral perfusion disorders secondary to collagenosis. In subjective terms, intravenous administration of these agents produces success in more than 50% of patients. The therapeutic outcome of clinical administration of alprostadil or iloprost may vary from individual to individual. Patients and methods: The following variables were analysed in a cross-over study in 27 patients with collagenosis and Raynaud’s phenomenon: plasma viscosity and erythrocyte aggregation (rheological variables), partial pressure of oxygen and laser Doppler flowmetry in the finger region, and lymphocyte phenotyping and interleukin (IL) determinations (immunological variables). Results: Laser Doppler flowmetry revealed significant differences between patients with secondary Raynaud’s phenomenon and a control group of 25 healthy subjects. Laser Doppler readings did not change significantly as a result of the treatments. Therapy with iloprost produced a reduction in IL-1beta, L-selectin (CD 62 L) and IL-6. Conclusion: The change in immunological variables due to iloprost may explain the long-term effects of prostaglandins in the treatment of Raynaud’s phenomenon. From our results it is not possible to infer any preference for iloprost or alprostadil.


1964 ◽  
Vol 03 (01) ◽  
pp. 11-19 ◽  
Author(s):  
A. Proppe

SummaryCase histories suitable for statistical evaluation can be found even as far back as in the Corpus Hippocraticum. Such simple data as the patient’s age, body weight, size, the date of menarche, etc. are practically always included in the case records, and it is demonstrated that, when such data are recorded in a system of documentation suitable for mechanical sorting, it may enable us to draw conclusions of very great importance. Mechanical registration methods have revealed that, in the determination and recording of data as hitherto carried out. there has been a surprisingly large number of errors and a high degree of unreliability. This view has a considerable influence on modern clinical methods; it renders a more democratic relation between physician and patient necessary and makes clear the need for measures to enhance the reliability of diagnosis and treatment of pathological conditions. The author illustrates this view with reference to the mechanical falsification of the thesis of the proneness of early age groups to lupus vulgaris, furthermore with reference to the mechanical rationalization of modern routine diagnostic methods, to the constant surveillance of adverse effects on public health and to the protection against allergic reactions with the aid of recording systems of personal allergy and intolerance data with mechanical sorting and computer techniques.


2020 ◽  
pp. 75-81
Author(s):  
Svetlana Alexandrovna Kosareva ◽  

The paper describes the method for increasing the level of self-organisation in students which has been developed by the author. It also contains the method testing results and presents the prospects and risks teachers could face while applying the method in a higher education institution. The purpose of this study is to find out the prospects and risks of applying the method for increasing the level of self-organisation in students and to determine the ways of reducing the risks. Methodology. The author points out the learning approaches which were the basis of developing the method and describes diagnostic methods for determining students’ self-organisation levels. The work focused on increasing each student’s initial level consists of a theoretical and a practical part and includes project activities on creating a study guide. The results of the study. The method developed proved to be effective. It was established by diagnosing the final level of self-organisation in students in the experimental and control groups. The paper considers the advantages of the method among which there is universal character, flexibility, improvements to teacher’s and students’ professional competence, etc. At the same time it is necessary to be aware of the risks due to the increased amount of teacher’s work and the fact that students’ work within the project tends to be monotonous. In conclusion, the prospects of the method for increasing the level of self-organisation in students are related to its advantages and the final results of the work. The risks of its use can be reduced with the help of the measures proposed in the paper.


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