TECHNOLOGIES OF AUTOMATED NOTIFICATION OF HUMAN HEALTH AND PERFORMANCE RISKS UNDER HYPOXIC HYPOXIA

Author(s):  
Nikolay Markov ◽  
Vladimir Filatov

The technologies of automated notification of health risks and human performance under hypoxic hypoxia are described, which provide the calculation and presentation in real time of visual and acoustic information about the value of the assessment of the reserve time for maintaining human health and performance under hypoxic hypoxia

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Zarana S. Patel ◽  
Tyson J. Brunstetter ◽  
William J. Tarver ◽  
Alexandra M. Whitmire ◽  
Sara R. Zwart ◽  
...  

Abstract NASA’s plans for space exploration include a return to the Moon to stay—boots back on the lunar surface with an orbital outpost. This station will be a launch point for voyages to destinations further away in our solar system, including journeys to the red planet Mars. To ensure success of these missions, health and performance risks associated with the unique hazards of spaceflight must be adequately controlled. These hazards—space radiation, altered gravity fields, isolation and confinement, closed environments, and distance from Earth—are linked with over 30 human health risks as documented by NASA’s Human Research Program. The programmatic goal is to develop the tools and technologies to adequately mitigate, control, or accept these risks. The risks ranked as “red” have the highest priority based on both the likelihood of occurrence and the severity of their impact on human health, performance in mission, and long-term quality of life. These include: (1) space radiation health effects of cancer, cardiovascular disease, and cognitive decrements (2) Spaceflight-Associated Neuro-ocular Syndrome (3) behavioral health and performance decrements, and (4) inadequate food and nutrition. Evaluation of the hazards and risks in terms of the space exposome—the total sum of spaceflight and lifetime exposures and how they relate to genetics and determine the whole-body outcome—will provide a comprehensive picture of risk profiles for individual astronauts. In this review, we provide a primer on these “red” risks for the research community. The aim is to inform the development of studies and projects with high potential for generating both new knowledge and technologies to assist with mitigating multisystem risks to crew health during exploratory missions.


2013 ◽  
Vol 244-245 ◽  
pp. 225-239 ◽  
Author(s):  
Mojgan Yeganeh ◽  
Majid Afyuni ◽  
Amir-Hosein Khoshgoftarmanesh ◽  
Loghman Khodakarami ◽  
Manouchehr Amini ◽  
...  

2021 ◽  
Vol 71 (1) ◽  
Author(s):  
Trishala Gopikrishna ◽  
Harini Keerthana Suresh Kumar ◽  
Kumar Perumal ◽  
Elavarashi Elangovan

Abstract Purpose Fermented soybean foods (FSF) is popularly consumed in the South-East Asian countries. Bacillus species, a predominant microorganism present in these foods, have demonstrated beneficial and deleterious impacts on human health. These microorganisms produce bioactive compounds during fermentation that have beneficial impacts in improving human health. However, the health risks associated with FSF, food pathogens, biogenic amines (BAs) production, and late-onset anaphylaxis, remain a concern. The purpose of this review is to present an in-depth analysis of positive and negative impacts as a result of consumption of FSF along with the measures to alleviate health risks for human consumption. Methods This review was composed by scrutinizing contemporary literature of peer-reviewed publications related to Bacillus and FSF. Based on the results from academic journals, this review paper was categorized into FSF, role of Bacillus species in these foods, process of fermentation, beneficial, and adverse influence of these foods along with methods to improve food safety. Special emphasis was given to the potential benefits of bioactive compounds released during fermentation of soybean by Bacillus species. Results The nutritional and functional properties of FSF are well-appreciated, due to the release of peptides and mucilage, which have shown health benefits: in managing cardiac disease, gastric disease, cancer, allergies, hepatic disease, obesity, immune disorders, and especially microbial infections due to the presence of probiotic property, which is a potential alternative to antibiotics. Efficient interventions were established to mitigate pitfalls like the techniques to reduce BAs and food pathogens and by using a defined starter culture to improve the safety and quality of these foods. Conclusion Despite some of the detrimental effects produced by these foods, potential health benefits have been observed. Therefore, soybean foods fermented by Bacillus can be a promising food by integrating effective measures for maintaining safety and quality for human consumption. Further, in vivo analysis on the activity and dietary interventions of bioactive compounds among animal models and human volunteers are yet to be achieved which is essential to commercialize them for safe consumption by humans, especially immunocompromised patients.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Abdur Rahman ◽  
N. C. Mondal ◽  
K. K. Tiwari

AbstractAn increased nitrate (NO3−) concentration in groundwater has been a rising issue on a global scale in recent years. Different consumption mechanisms clearly illustrate the adverse effects on human health. The goal of this present study is to assess the natural and anthropogenic NO3− concentrations in groundwater in a semi arid area of Rajasthan and its related risks to human health in the different groups of ages such as children, males, and females. We have found that most of the samples (n = 90) were influenced by anthropogenic activities. The background level of NO3− had been estimated as 7.2 mg/L using a probabilistic approach. About 93% of nitrate samples exceeded the background limit, while 28% of the samples were beyond the permissible limit of 45 mg/L as per the BIS limits. The results show that the oral exposure of nitrate was very high as compare to dermal contact. With regard to the non-carcinogenic health risk, the total Hazard Index (HITotal) values of groundwater nitrate were an average of 0.895 for males, 1.058 for females, and 1.214 for children. The nitrate health risk assessment shows that about 38%, 46%, and 49% of the samples constitute the non-carcinogenic health risk to males, females, and children, respectively. Children were found to be more prone to health risks due to the potential exposure to groundwater nitrate.


Water ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 783
Author(s):  
Feifei Chen ◽  
Leihua Yao ◽  
Gang Mei ◽  
Yinsheng Shang ◽  
Fansheng Xiong ◽  
...  

Groundwater is a valuable water source for drinking and irrigation purposes in semiarid regions. Groundwater pollution may affect human health if it is not pretreated and provided for human use. This study investigated the hydrochemical characteristics driving groundwater quality for drinking and irrigation purposes and potential human health risks in the Xinzhou Basin, Shanxi Province, North China. More specifically, we first investigated hydrochemical characteristics using a descriptive statistical analysis method. We then classified the hydrochemical types and analyzed the evolution mechanisms of groundwater using Piper and Gibbs diagrams. Finally, we appraised the groundwater quality for drinking and irrigation purposes using the entropy water quality index (EWQI). We assessed the associated human health risks for different age and sex groups through drinking intake and dermal contact pathways. Overall, we found that (1) Ca-HCO3 and Ca·Mg-HCO3 were the dominant hydrochemical types and were mainly governed by rock weathering and water–rock interactions. (2) Based on the EWQI classifications, 67.74% of the groundwater samples were classified as medium quality and acceptable for drinking purpose. According to the values of sodium adsorption ratio (SAR), residual sodium carbonate (RSC) and soluble sodium percentage (%Na), 90.32% of the samples were suitable for irrigation, while the remaining samples were unfit for irrigation because of the high salinity in the groundwater. (3) Some contaminants in the groundwater, such as NO3−, NO2− and F−, exceeded the standard limits and may cause potential risks to human health. Our work presented in this paper could establish reasonable management strategies for sustainable groundwater quality protection to protect public health.


Author(s):  
Afef Hfaiedh ◽  
Ahmed Chemori ◽  
Afef Abdelkrim

In this paper, the control problem of a class I of underactuated mechanical systems (UMSs) is addressed. The considered class includes nonlinear UMSs with two degrees of freedom and one control input. Firstly, we propose the design of a robust integral of the sign of the error (RISE) control law, adequate for this special class. Based on a change of coordinates, the dynamics is transformed into a strict-feedback (SF) form. A Lyapunov-based technique is then employed to prove the asymptotic stability of the resulting closed-loop system. Numerical simulation results show the robustness and performance of the original RISE toward parametric uncertainties and disturbance rejection. A comparative study with a conventional sliding mode control reveals a significant robustness improvement with the proposed original RISE controller. However, in real-time experiments, the amplification of the measurement noise is a major problem. It has an impact on the behaviour of the motor and reduces the performance of the system. To deal with this issue, we propose to estimate the velocity using the robust Levant differentiator instead of the numerical derivative. Real-time experiments were performed on the testbed of the inertia wheel inverted pendulum to demonstrate the relevance of the proposed observer-based RISE control scheme. The obtained real-time experimental results and the obtained evaluation indices show clearly a better performance of the proposed observer-based RISE approach compared to the sliding mode and the original RISE controllers.


Author(s):  
Gaurav Chaurasia ◽  
Arthur Nieuwoudt ◽  
Alexandru-Eugen Ichim ◽  
Richard Szeliski ◽  
Alexander Sorkine-Hornung

We present an end-to-end system for real-time environment capture, 3D reconstruction, and stereoscopic view synthesis on a mobile VR headset. Our solution allows the user to use the cameras on their VR headset as their eyes to see and interact with the real world while still wearing their headset, a feature often referred to as Passthrough. The central challenge when building such a system is the choice and implementation of algorithms under the strict compute, power, and performance constraints imposed by the target user experience and mobile platform. A key contribution of this paper is a complete description of a corresponding system that performs temporally stable passthrough rendering at 72 Hz with only 200 mW power consumption on a mobile Snapdragon 835 platform. Our algorithmic contributions for enabling this performance include the computation of a coarse 3D scene proxy on the embedded video encoding hardware, followed by a depth densification and filtering step, and finally stereoscopic texturing and spatio-temporal up-sampling. We provide a detailed discussion and evaluation of the challenges we encountered, as well as algorithm and performance trade-offs in terms of compute and resulting passthrough quality.;AB@The described system is available to users as the Passthrough+ feature on Oculus Quest. We believe that by publishing the underlying system and methods, we provide valuable insights to the community on how to design and implement real-time environment sensing and rendering on heavily resource constrained hardware.


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