The Effects of Hand Moxibustion and Hand Press Pellet on Blood Pressure, Blood Lipids and Blood Cell Components in Aged Women with Essential Hypertension

Hypertension and dyslipidemia exhibit an important clinical relationship because an increase in blood lipids yields an increase in blood pressure (BP). We analyzed the associations of seven polymorphisms of genes involved in lipid metabolism (APOA5rs3135506,APOBrs1042031,FABP2rs1799883,LDLRrs5925,LIPCrs1800588,LPLrs328, andMTTPrs1800591) with blood pressure and lipid values in Mexican hypertensive (HT) patients. A total of 160 HT patients and 160 normotensive individuals were included. Genotyping was performed through PCR-RFLP, PCR-AIRS, and sequencing. The results showed significant associations in the HT group and HT subgroups classified as normolipemic and hyperlipemic. The allelesFABP2p.55T,LIPC−514T, andMTTP−493T were associated with elevated systolic BP. Five alleles were associated with lipids.LPLp.474X andFABP2p.55T were associated with decreased total cholesterol and LDL-C, respectively;APOA5p.19W with increased HDL-C;APOA5p.19W andFABP2p.55T with increased triglycerides; andAPOBp.4181K andLDLRc.1959T with decreased triglycerides. TheAPOBp.E4181K polymorphism increases the risk for HT (OR = 1.85, 95% CI: 1.17–2.93;P=0.001) under the dominant model. These findings indicate that polymorphisms of lipid metabolism genes modify systolic BP and lipid levels and may be important in the development of essential hypertension and dyslipidemia in Mexican HT patients.

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BLOOD PRESSURE AND BLOOD LIPIDS IN MEMBERS OF FAMILIES WITH A HEAVY AGGREGATION OF ESSENTIAL HYPERTENSION

Acta Medica Scandinavica ◽

10.1111/j.0954-6820.1974.tb00959.x ◽

2009 ◽

Vol 196 (1-6) ◽

pp. 11-16 ◽

Cited By ~ 5

Author(s):

Göran Friman ◽

Urban Waern

Keyword(s):

Blood Pressure ◽

Essential Hypertension ◽

Blood Lipids

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The relationship between red blood cell distribution width and blood pressure abnormal dipping in patients with essential hypertension: a cross-sectional study

BMJ Open ◽

10.1136/bmjopen-2015-010456 ◽

2016 ◽

Vol 6 (2) ◽

pp. e010456 ◽

Cited By ~ 6

Author(s):

Dan Su ◽

Qi Guo ◽

Ya Gao ◽

Jin Han ◽

Bin Yan ◽

...

Keyword(s):

Blood Pressure ◽

Essential Hypertension ◽

Blood Cell ◽

Cross Sectional Study ◽

Cell Distribution ◽

Sectional Study ◽

Cross Sectional ◽

Distribution Width ◽

The Relationship ◽

Red Blood Cell Distribution

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Effects of PTH(1–34) on blood pressure, renal function, and hormones in essential hypertension Thealtered pattern of reactivity may counteract raised blood pressure

American Journal of Hypertension ◽

10.1016/s0895-7061(97)90506-9 ◽

1997 ◽

Vol 10 (10) ◽

pp. 1356-1367

Author(s):

B Jespersen

Keyword(s):

Blood Pressure ◽

Renal Function ◽

Essential Hypertension

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Triamterene-induced changes in aldosterone and renin values in essential hypertension. Evidence of a role for aldosterone in preventing blood pressure reduction

Archives of Internal Medicine ◽

10.1001/archinte.136.6.645 ◽

1976 ◽

Vol 136 (6) ◽

pp. 645-648 ◽

Cited By ~ 4

Author(s):

H. J. Keim

Keyword(s):

Blood Pressure ◽

Essential Hypertension ◽

Blood Pressure Reduction ◽

Pressure Reduction ◽

Induced Changes

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Haematocrit: Relationships with Blood Lipids, Blood Pressure and other Cardiovascular Risk Factors

Thrombosis and Haemostasis ◽

10.1055/s-0038-1648811 ◽

1994 ◽

Vol 72 (01) ◽

pp. 058-064 ◽

Cited By ~ 14

Author(s):

Goya Wannamethee ◽

A Gerald Shaper

Keyword(s):

Physical Activity ◽

Risk Factors ◽

Blood Pressure ◽

Body Mass Index ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors ◽

Alcohol Intake ◽

Blood Lipids ◽

The Other ◽

The Relationship

SummaryThe relationship between haematocrit and cardiovascular risk factors, particularly blood pressure and blood lipids, has been examined in detail in a large prospective study of 7735 middle-aged men drawn from general practices in 24 British towns. The analyses are restricted to the 5494 men free of any evidence of ischaemic heart disease at screening.Smoking, body mass index, physical activity, alcohol intake and lung function (FEV1) were factors strongly associated with haematocrit levels independent of each other. Age showed a significant but small independent association with haematocrit. Non-manual workers had slightly higher haematocrit levels than manual workers; this difference increased considerably and became significant after adjustment for the other risk factors. Diabetics showed significantly lower levels of haematocrit than non-diabetics. In the univariate analysis, haematocrit was significantly associated with total serum protein (r = 0*18), cholesterol (r = 0.16), triglyceride (r = 0.15), diastolic blood pressure (r = 0.17) and heart rate (r = 0.14); all at p <0.0001. A weaker but significant association was seen with systolic blood pressure (r = 0.09, p <0.001). These relationships remained significant even after adjustment for age, smoking, body mass index, physical activity, alcohol intake, lung function, presence of diabetes, social class and for each of the other biological variables; the relationship with systolic blood pressure was considerably weakened. No association was seen with blood glucose and HDL-cholesterol. This study has shown significant associations between several lifestyle characteristics and the haematocrit and supports the findings of a significant relationship between the haematocrit and blood lipids and blood pressure. It emphasises the role of the haematocrit in assessing the risk of ischaemic heart disease and stroke in individuals, and the need to take haematocrit levels into account in determining the importance of other cardiovascular risk factors.

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