Evaluation of the Response of Fractional Carbon Dioxide (CO2) Laser and Punch Elevation Technique in Treatment of Acne Scars : A Split-Face Comparative Clinical, Histopathological and Immune Histochemical Study

Background: Many interventions have been used to treat post-acne scars, with various degrees of efficacy and adverse reactions. Multimodal approach can achieve better results for improving the physical appearance that even if minor may result in significant distress and reduced quality of life. Objective: To compare the efficacy of subcision with fractional carbon dioxide (CO2) laser and subcision with microneedling fractional radiofrequency (RF) in treating post-acne scars and to study their adverse effects. Methods: In this prospective, interventional clinical study, a total of 64 patients with post-acne scars were enrolled. The patients were randomly allocated into two groups of 32 patients each, in which group A was treated with subcision plus fractional carbon dioxide laser (CO2) and group B was treated with subcision plus microneedling fractional radiofrequency (RF) every 6 weeks for a total of four sittings. An objective score was calculated for each patient using the Goodman and Baron scale to evaluate the outcome every visit during treatment and then 3 months after completion of therapy. Results: In group A, the percentage reduction in the mean objective scores was found to be 64%. In group B, the percentage reduction in mean objective scores was found to be 42%. Most of the changes were seen in the boxcar and rolling types of scars. Conclusions: Subcision and fractional CO2 laser were considered superior over subcision with microneedling fractional (RF) technique for the treatment of post-acne scars. Boxcar and rolling types of scars showed a high response to treatment than icepick scars

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Evaluasi Terapi Laser Fraksional Karbon Dioksida pada Penatalaksanaan Acne Scars

10.31227/osf.io/zpc7d ◽

2019 ◽

Author(s):

Jasmine Rahmi Hapsari

Keyword(s):

Carbon Dioxide ◽

Laser Treatment ◽

Co2 Laser ◽

Skin Inflammation ◽

Treatment Choices ◽

National Medical ◽

Acne Scars ◽

Carbon Dioxide Co2 ◽

Made In

Acne scars is framed after serious scenes of skin inflammation in high schooler and early grown-up years. A few treatment choices have been utilized for discouraged skin break out scars, for example, punch joining, punch extraction, fractional carbon dioxide (CO2) laser and so on. In addition, Studies demonstrate that laser skin reemerging, for example, CO2 partial can viably treat discouraged skin inflammation scars. Huge advances have been made in the restorative utilization of the laser in the previous couple of decades. Numerous illnesses in the dermatological field are currently signs for laser treatment that meet all requirements for repayment by numerous national medical coverage frameworks. Among laser types, the fractional carbon dioxide (CO2) laser remains a significant framework for the dermatologist

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Efficacy and Side Effects of Fractional Carbon Dioxide Laser for Acne Scars, Keloids, and Striae Albae in the Dermatovenereology Clinic of Tertiary Hospital: A Retrospective Study

Berkala Ilmu Kesehatan Kulit dan Kelamin ◽

10.20473/bikk.v33.1.2021.19-27 ◽

2021 ◽

Vol 33 (1) ◽

pp. 19

Author(s):

Riezky Januar Pramitha ◽

Iskandar Zulkarnain ◽

Evy Ervianti ◽

Rahmadewi Rahmadewi ◽

Afif Nurul Hidayati ◽

...

Keyword(s):

Carbon Dioxide ◽

Side Effects ◽

Co2 Laser ◽

Carbon Dioxide Laser ◽

Scar Tissue ◽

Tertiary Hospital ◽

Fractional Co2 Laser ◽

Acne Scars ◽

Laser Treatments ◽

Carbon Dioxide Co2

Background: Fractional Carbon Dioxide (CO2) LASER has better efficacy compared to conventional LASER in treating scar tissue such as acne scars, keloids, and striae albae. However, a population with darker skin has a higher risk of side effects, especially in post-inflammatory hyperpigmentation. Purpose: To evaluate the efficacy and side effects of fractional CO2 LASER in new patients with acne scars, keloids, and striae albae in the Dermatovenereology outpatient clinic. Methods: Retrospective analysis was done on 42 medical records of patients who met the inclusion criterion, which was those who have undergone fractional CO2 LASER treatments. The efficacy and side effects of the therapy were identified and analyzed using the Statistical Package for Social Sciences (SPSS) version 17 program. Result: A total of 42.9% of patients underwent fractional CO2 LASER treatments for acne scars, while 31% and 26.1% of patients received treatments for keloids and striae albae, respectively. There was a statistically significant decrease in the degree of acne scar (2.72 ± 0.83), keloid height (2.2 ± 0.405), and striae width (0.39 ± 0.02). The statistically significant side effects were hyperpigmentation (59.5%), crustae (26.2%), erythema ≥ for 4 days (19%), and new acne (19%). Conclusion: Fractional CO2 LASER was effective for treating scar tissue (acne scars, keloids, and striae albae) with a higher incidence of side effects in population with darker skin and post-inflammatory hyperpigmentation.

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Evaluation of autologous adipose‐derived stem cells vs. fractional carbon dioxide laser in the treatment of post acne scars: a split‐face study

International Journal of Dermatology ◽

10.1111/ijd.14567 ◽

2019 ◽

Vol 58 (10) ◽

pp. 1212-1222 ◽

Cited By ~ 3

Author(s):

Rania S. Abou Eitta ◽

Aisha A. Ismail ◽

Rania A. Abdelmaksoud ◽

Naser A. Ghezlan ◽

Radwa A. Mehanna

Keyword(s):

Carbon Dioxide ◽

Stem Cells ◽

Carbon Dioxide Laser ◽

Adipose Derived Stem Cells ◽

Acne Scars ◽

Fractional Carbon Dioxide Laser ◽

Split Face

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Split face comparative study of microneedling with platelet rich plasma versus Fractional carbon dioxide laser with platelet rich plasma in treatment of atrophic post acne scars

QJM ◽

10.1093/qjmed/hcab093.001 ◽

2021 ◽

Vol 114 (Supplement_1) ◽

Author(s):

Mohamed Abd Elnaeem Sallam ◽

Khaled El Zawahry ◽

Abdul Rahman Muhammed Ali Mustafa

Keyword(s):

Carbon Dioxide ◽

Co2 Laser ◽

Carbon Dioxide Laser ◽

Platelet Rich Plasma ◽

Fractional Co2 Laser ◽

Acne Scars ◽

Significant Difference ◽

Before And After ◽

The Face ◽

Fractional Carbon Dioxide Laser

Abstract Background Acne scars, is a challenge for dermatologists, despite having multiple treatment modalities like microneedling, dermabrasion, Fractional CO2 Laser, dermal fillers, etc. However, monotherapy has been hardly satisfactory because of the polymorphism seen with the scars. Objective Comparison between microneedling with platelet rich plasma versus Fractional carbon dioxide laser with platelet rich plasma in treatment of atrophic post acne scars. Patients and methods This study was carried out in department of dermatology, venereology and andrology, in Kobry El-Kobba Military complex during the period (from September 2018 to July 2020 ) on 20 patients of both sexes aged from 20 to 60 years old presenting with Goodman and Baron Grade II, III, IV acne scars . Results The study revealed a statistically significant difference (p = 0.017) between Goodman and Baron scar grades on the right side of the face before and after treatment indicating that microneedling with platelet rich plasma was effective in improving acne scars. Also, there is a statistically significant difference (p = 0.010) between Goodman and Baron scar grades on the left side of the face before and after treatment, indicating that fractional CO2 laser with platelet rich plasma was effective in improving acne scars. Conclusion and recommendation Further controlled and randomized studies are needed to validate our findings in a larger cohort of patients and longer follow up. Also, number of sessions might be more than 3 sessions.

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Comparison Study of Fractional Carbon Dioxide Laser Resurfacing Using Different Fluences and Densities for Acne Scars in Asians: A Randomized Split-Face Trial

Dermatologic Surgery ◽

10.1111/dsu.12467 ◽

2014 ◽

Vol 40 (5) ◽

pp. 545-552 ◽

Cited By ~ 11

Author(s):

Xing-Hua Yuan ◽

Shu-Xia Zhong ◽

Shan-Shan Li

Keyword(s):

Carbon Dioxide ◽

Carbon Dioxide Laser ◽

Comparison Study ◽

Laser Resurfacing ◽

Acne Scars ◽

Fractional Carbon Dioxide Laser ◽

Split Face

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Whole Area versus Focal Acne Scar Treatment (FAST) of Post Acne-Scars by Fractional CO2 Laser: A Comparative Study

QJM ◽

10.1093/qjmed/hcaa046.014 ◽

2020 ◽

Vol 113 (Supplement_1) ◽

Author(s):

M A Abdallah ◽

C K T Gobrial ◽

S G H Gomah

Keyword(s):

Comparative Study ◽

Co2 Laser ◽

Acne Scar ◽

Fractional Co2 Laser ◽

Acne Scars ◽

Scar Treatment ◽

Acne Scarring ◽

Facial Area ◽

The Right ◽

Split Face

Abstract Background Acne scarring is often the primary concern of a patient with acne. Acne scarring can cause depression and is a risk factor for suicide. Patients feel their appearance interferes with their relationships and chances of future employment. Acne scars can be classified into 3 different types: atrophic, hypertrophic, or keloidal. Atrophic acne scars are the most common type. Atrophic acne scars are divided into three main types: ice pick, rolling and boxcar scars. Aim of the Work To compare the results of whole facial area versus Focal Acne Scar Treatment (FAST) by factional CO2 laser in a split face study. Patients and Methods The present study is a split face comparative study which included 20 adult patients with atrophic acne scars ranged from 18 to 44 years old of both sex. The study was approved by the Research Ethical Committee, Faculty of Medicine, Ain Shams University and fulfilled all the ethical aspects required in human research. All patients received full information about description of the procedure of treatment, possible side effects, photo documentation and they all provided written consent. Results Patients were asked to compare the pain, peeling and complications between the right and left sides post CO2 fractional treatment: pain was more at right side in 35% of cases and more at left side in 30% of cases and equal in the rest of cases, peeling was faster at the right side in 60% of cases, faster at the left side in 20% of cases and equal at the rest of cases, 4 of the patients had post inflammatory hyperpigmentation (1 patient at right side, 2 patients at left side and 1 patient at both sides), no other complications were recorded as secondary infection, scaring keloid and prolonged erythema. Conclusion We compared the results of whole facial area treatment in the right side of the face versus Focal Acne Scar Treatment (FAST) in the left side by factional CO2 laser. We discovered that there is a statistically highly significant relationship between the improvement of acne scars and treatment with fractional CO2 laser by the either techniques. Both techniques are preferable in treating acne scars in equal degree.

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Improvement of Microstomia in Scleroderma after Carbon Dioxide Laser Treatment

Case Reports in Dermatology ◽

10.1159/000445821 ◽

2016 ◽

Vol 8 (2) ◽

pp. 142-150 ◽

Cited By ~ 9

Author(s):

Imane Bennani ◽

Raphael Lopez ◽

Delphine Bonnet ◽

Gregoire Prevot ◽

Arnaud Constantin ◽

...

Keyword(s):

Carbon Dioxide ◽

Systemic Sclerosis ◽

Laser Treatment ◽

Co2 Laser ◽

Carbon Dioxide Laser ◽

Treatment Options ◽

Mouth Opening ◽

Global Evaluation ◽

Pulsed Co2 Laser ◽

Carbon Dioxide Co2

Limited mouth opening (LMO) is a frequent complication of systemic sclerosis (SS). Its management is complex and there are limited treatment options. We report four patients with SS and severe LMO [interincisal distance (IID) <30 mm] treated with pulsed carbon dioxide (CO2) laser. Pulsed CO2 laser treatment of the white lips was performed after all patients had signed a written informed consent in the absence of alternative treatment. Treatment was carried out under locoregional anaesthesia using a Sharplan 30C CO2 laser in the Silk Touch® resurfacing mode. One to three laser sessions were performed at intervals of 8-12 months between sessions. Assessments were performed at 3 and 12 months with measurement of the IID using a ruler, calculation of the Mouth Handicap in Systemic Sclerosis (MHISS) scale and global evaluation by the patients. Adverse events were also reported. In all four patients, an improvement in IID occurred 3 months after the first session with a mean gain of +5 mm (range: 2-7). At 12 months, a mean gain of +8.5 mm (range: 7-10) in IID was observed. The MHISS score decreased by a mean of -14 (range: 11-17). All patients showed improvement of lip flexibility or mouth opening, allowing better phonation and mastication and easier dental care. Adverse effects were transient erythema and/or dyschromia. CO2 laser appears to be effective and well tolerated in the improvement of LMO in SS.

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