scholarly journals Bismuth (III) Triflate: A Mild, Efficient Promoter for the Synthesis of Trisubstituted Alkenes through Knoevenagel Condensation

2020 ◽  
Vol 36 (05) ◽  
pp. 843-849
Author(s):  
Arup Datta
Keyword(s):  
Catalytic Activity ◽  
Knoevenagel Condensation ◽  
Condensation Product ◽  
Ethyl Cyanoacetate ◽  
Free Condition ◽  
Solvent Free Condition ◽  
Two Component ◽  
Active Methylene Compounds ◽  
Trisubstituted Alkenes ◽  
Active Methylene

In this work, smooth efficient and eco-friendly two component coupling method is reported for the synthesis of Knoevenagel Condensation product in presence of Bi(OTf)3 catalyst under solvent free condition. Catalyst has participated in condensation between substituted aldehydes (aromatic and hetero-aromatic) and active methylene compounds (ethyl cyanoacetate, malononitrile and cyanoacetamide) effectively to generate an excellent yield of the product. Bi(OTf)3 catalyst is stable, inexpensive and easily available was used for four times in this reaction without loss of catalytic activity.

scholarly journals L-Tyrosine as an Eco-Friendly and Efficient Catalyst for Knoevenagel Condensation of Arylaldehydes with Meldrum’s Acid in Solvent-Free Condition under Grindstone Method

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
G. Thirupathi ◽  
M. Venkatanarayana ◽  
P. K. Dubey ◽  
Y. Bharathi Kumari
Keyword(s):  
Room Temperature ◽  
Knoevenagel Condensation ◽  
Solvent Free ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
Efficient Catalyst ◽  
Free Condition ◽  
Solvent Free Condition ◽  
Active Methylene ◽  
Methylene Group

We investigate L-Tyrosine as an efficient catalyst for the Knoevenagel condensation of arylaldehydes with meldrum’s acid containing cyclic active methylene group in solvent-free condition under grindstone method at room temperature to produce substituted-5-benzylidene-2,2-dimethyl-[1,3]dioxane-4,6-diones 3(a–j).

The remarkable catalytic activity of ultra-small free-CeO2 nanoparticles in selective carbon–carbon bond formation reactions in water at room temperature

2015 ◽  
Vol 39 (7) ◽  
pp. 5350-5353 ◽  
Author(s):  
Subhash Banerjee
Keyword(s):  
Catalytic Activity ◽  
Room Temperature ◽  
Bond Formation ◽  
Ceo2 Nanoparticles ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Reusable Catalyst ◽  
Carbon Carbon Bond ◽  
Active Methylene Compounds ◽  
Active Methylene

A simple and efficient protocol for selective bis-Michael addition and mono-allylation of active methylene compounds has been demonstrated using ultra-small size (∼5 nm) uncapped cerium oxide nanoparticles (free-CeO2 NPs) as a reusable catalyst in water at room temperature.

scholarly journals Cellulose sulphuric acid as a biodegradable and reusable catalyst for the Knoevenagel condensation

2010 ◽  
Vol 8 (1) ◽  
pp. 12-18 ◽  
Author(s):  
Kiran Shelke ◽  
Suryakant Sapkal ◽  
Kirti Niralwad ◽  
Bapurao Shingate ◽  
Murlidhar Shingare
Keyword(s):  
Sulphuric Acid ◽  
Knoevenagel Condensation ◽  
Ethyl Cyanoacetate ◽  
Reaction Times ◽  
Significant Loss ◽  
Reusable Catalyst ◽  
Environmental Friendliness ◽  
Solvent Free Condition ◽  
High Yields ◽  
Work Up

AbstractA green, mild and efficient method for Knoevenagel condensation of 3-formylchromone/2-chlroquinoline-3-carbaldehyde with active methylene compounds such as Meldrum’s acid/ethyl cyanoacetate using biosupported cellulose sulphuric acid (CSA) in the solid-state by grinding under solvent-free condition has been developed. This method provides several advantages including environmental friendliness, shor t reaction times, high yields and a simple work-up procedure. Moreover, the CSA was successfully reused for four cycles without significant loss of activity.

Et3N- Promoted Cascade Sp3C-H Bond Functionalization of Methyl Arene with Active Methylene CompoundsUnder Solvent-Free Condition

2019 ◽  
Vol 4 (7) ◽  
pp. 2225-2228 ◽  
Author(s):  
Dhirendra Kumar ◽  
Savita Kumari ◽  
Somaiah Gajaganti ◽  
Vandana Srivastava ◽  
Sundaram Singh
Keyword(s):  
Solvent Free ◽  
Bond Functionalization ◽  
Free Condition ◽  
Solvent Free Condition ◽  
Active Methylene
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