scholarly journals Building Orientation Courses for Online Programs: The GeoIntelligence Certificate Case

2014 ◽  
Vol 6 ◽  
Author(s):  
Nektaria Tryfona
Keyword(s):  
Online Programs ◽  
Building Orientation ◽  
Orientation Courses

scholarly journals Orientation Courses for Medical Students

1949 ◽  
Vol 24 (2) ◽  
pp. 65-74
Author(s):  
Thomas M. Perry
Keyword(s):  
Medical Students ◽  
Orientation Courses

scholarly journals Case Study of a Heavily Damaged Building during the 2016 MW 7.8 Ecuador Earthquake: Directionality Effects in Seismic Actions and Damage Assessment

Geosciences ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 74
Author(s):  
Luis A. Pinzón ◽  
Luis G. Pujades ◽  
Irving Medranda ◽  
Rodrigo E. Alva
Keyword(s):  
Damage Assessment ◽  
Strong Motion ◽  
Response Spectra ◽  
Seismic Action ◽  
Damage State ◽  
Ground Acceleration ◽  
Intensity Measures ◽  
Capacity Curves ◽  
Building Orientation

In this work, the directionality effects during the MW 7.8 earthquake, which occurred in Muisne (Ecuador) on 16 April 2016, were analyzed under two perspectives. The first one deals with the influence of these effects on seismic intensity measures (IMs), while the second refers to the assessment of the expected damage of a specific building located in Manta city, Ecuador, as a function of its azimuthal orientation. The records of strong motion in 21 accelerometric stations were used to analyze directionality in seismic actions. At the closest station to the epicenter (RRup = 20 km), the peak ground acceleration was 1380 cm/s2 (EW component of the APED station). A detailed study of the response spectra ratifies the importance of directionality and confirms the need to consider these effects in seismic hazard studies. Differences between IMs values that consider the directionality and those obtained from the as-recorded accelerograms are significant and they agree with studies carried out in other regions. Concerning the variation of the expected damage with respect to the building orientation, a reinforced concrete building, which was seriously affected by the earthquake, was taken as a case study. For this analysis, the accelerograms recorded at a nearby station and detailed structural documentation were used. The ETABS software was used for the structural analysis. Modal and pushover analyses were performed, obtaining capacity curves and capacity spectra in the two main axes of the building. Two advanced methods for damage assessment were used to obtain fragility and mean damage state curves. The performance points were obtained through the linear equivalent approximation. This allows estimation and analysis of the expected mean damage state and the probability of complete damage as functions of the building orientation. Results show that the actual probability of complete damage is close to 60%. This fact is mainly due to the greater severity of the seismic action in one of the two main axes of the building. The results are in accordance with the damage produced by the earthquake in the building and confirm the need to consider the directionality effects in damage and seismic risk assessments.

Emerging Framework for Planning and Implementation of Online Programs

2010 ◽  
Vol 1 (4) ◽  
pp. 1-16 ◽  
Author(s):  
Victor M. Hernández-Gantes
Keyword(s):  
Strategic Planning ◽  
Online Education ◽  
Program Planning ◽  
Successful Implementation ◽  
Online Programs ◽  
The Past ◽  
Effective Program ◽  
Assessment Strategies ◽  
Interactive Feedback ◽  
Dramatic Growth

The dramatic growth of online education over the past two decades is requiring colleges to make a shift from fragmented approaches to program planning and implementation towards a framework integrating both into a coherent support system. This article provides an overview of an emerging holistic framework for planning and implementation of online programs calling for shared strategic planning needs assessment strategies, and establishing program consensus. Guided by a program vision, curriculum and instructional strategies are identified along with internal and external supports needed for successful implementation. The framework suggests demand-driven strategic planning, benchmarking approaches to implementation practices, and interactive feedback to ensure effective program planning and implementation.

Online programs to strengthen mental health in medical students: a literature review (Preprint)

2021 ◽  
Author(s):  
Patrizia Ungar ◽  
Ann-Kathrin Schindler ◽  
Sabine Polujanski ◽  
Thomas Rotthoff
Keyword(s):  
Mental Health ◽  
Medical Students ◽  
Literature Search ◽  
Medical Profession ◽  
Behavioral Therapy ◽  
Individual Characteristics ◽  
Online Programs ◽  
Health Promoting ◽  
Medical Faculties ◽  
Prevention Approach

BACKGROUND Medical students are at an increasing risk of depression and burnout during their study period. This trend among future physicians is a cause for concern, given the great responsibility that the medical profession entails. Medical faculties therefore play a significant role in supporting medical students in maintaining their mental health. Especially in the context of the current COVID-19 pandemic, support services that allow greater flexibility in their use become particularly relevant. Online programs can be accessed from anywhere and any time and can be used individually in a safe or well-known setting. From a preventive perspective, individual characteristics that have been shown to be protective of mental health should be addressed in such programs. Before conceptualizing an online program, reviewing existing online programs for medical students is a first relevant step. OBJECTIVE This review provides an overview of the current online programs for medical students to strengthen their mental health by addressing individual characteristics believed to be protective of mental health and addressable in medical curricula. METHODS PubMed, ERIC, Cochrane, and Web of Science were used for a systematic literature search. The programs had to be offered digitally and address medical students. Preventive individual characteristics for mental health were included in the search to provide information on their role in the studies. Publications also should include information on the effectiveness of the respective programs. RESULTS The literature search yielded 592 articles; of them, only nine met the study criteria. The programs found included elements of cognitive-behavioral therapy, mindfulness training, or peer support. Regarding the mental health outcomes, two studies showed a significant reduction in perceived stress and one study indicated a reduced level of burnout. One program had significant immediate effects on mindfulness, empathy, and resilience; two studies indicated strengthening coping strategies. Two programs were qualitatively assessed as helpful. One study is still ongoing. CONCLUSIONS Only a few studies have assessed the effectiveness of online programs to strengthen medical students’ mental health. The programs found mostly addressed preventive individual characteristics but were not developed on the basis of a survey of medical students’ demands. Furthermore, they were provided as add-on programs; integration of such programs into the curriculum may highlight the relevance of mental health. For the development of future online programs, the concrete needs of the respective target group should be surveyed and taken into account. Based on this, suitable online programs can be developed in a targeted way to strengthen mental health by addressing preventive individual characteristics. This needs-based prevention approach can support health-promoting education of future physicians.

scholarly journals Knockdown of Long Noncoding RNA HOXA-AS2 Suppresses Chemoresistance of Acute Myeloid Leukemia via the miR-520c-3p/S100A4 Axis

2018 ◽  
Vol 51 (2) ◽  
pp. 886-896 ◽  
Author(s):  
Xiaoya Dong ◽  
Zhigang Fang ◽  
Mingxue Yu ◽  
Ling Zhang ◽  
Ruozhi Xiao ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Acute Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Luciferase Reporter Assay ◽  
Luciferase Reporter ◽  
Reporter Assay ◽  
Online Programs ◽  
Acute Myeloid

Background/Aims: Among different molecular candidates, there is growing data to support that long noncoding RNAs (lncRNAs) play a significant role in acute myeloid leukemia (AML). HOXA-AS2 is significantly overexpressed in a variety of tumors and associated with anti-cancer drug resistance, however, little is known regarding the expression and function of HOXA-AS2 in the chemoresistance of AML. In this study, we aimed to determine the role and molecular mechanism of HOXA-AS2 in adriamycin-based chemotherapy resistance in AML cells. Methods: Quantitative real-time PCR was used to detect HOXA-AS2 expression in the BM samples and ADR cell lines, U/A and T/A cells. Furthermore, the effects of HOXA-AS2 silencing on cell proliferation and apoptosis were assessed in vitro by CCK8 and flow cytometry, and on tumor growth in vivo. Furthermore, bioinformatics online programs predicted and luciferase reporter assay were used to validate the association of HOXA-AS2 and miR-520c-3p in AML. Results: In this study, we showed that HOXA-AS2 is significantly upregulated in BM samples from AML patients after treatment with adriamycin-based chemotherapy and in U/A and T/A cells. Knockdown of HOXA-AS2 inhibited ADR cell proliferation in vitro and in vivo and promoted apoptosis. Bioinformatics online programs predicted that HOXA-AS2 sponge miR-520c-3p at 3’-UTR with complementary binding sites, which was validated using luciferase reporter assay and anti-Ago2 RIP assay. HOXA-AS2 could negatively regulate the expression of miR-520c-3p in ADR cells. S100A4 was predicted as a downstream target of miR-520c-3p, which was confirmed by luciferase reporter assay. Conclusion: Our results suggest that HOXA-AS2 plays an important role in the resistance of AML cells to adriamycin. Thus, HOXA-AS2 may represent a therapeutic target for overcoming resistance to adriamycin-based chemotherapy in AML.

scholarly journals Maximizing the impact of E-Therapy and Serious Gaming: Time for a paradigm shift

2020 ◽  
Author(s):  
Theresa Fleming ◽  
D de Beurs ◽  
Y Khazaal ◽  
A Gaggioli ◽  
G Riva ◽  
...  
Keyword(s):  
Mental Health ◽  
Paradigm Shift ◽  
User Centered Design ◽  
Online Programs ◽  
Serious Gaming ◽  
Internet Interventions ◽  
Evidence Based Treatments ◽  
Population Mental Health ◽  
The Impact ◽  
User Centered

© 2016 Fleming, de Beurs, Khazaal, Gaggioli, Riva, Botella, Baños, Aschieri, Bavin, Kleiboer, Merry, Lau and Riper. Internet interventions for mental health, including serious games, online programs, and apps, hold promise for increasing access to evidence-based treatments and prevention. Many such interventions have been shown to be effective and acceptable in trials; however, uptake and adherence outside of trials is seldom reported, and where it is, adherence at least, generally appears to be underwhelming. In response, an international Collaboration On Maximizing the impact of E-Therapy and Serious Gaming (COMETS) was formed. In this perspectives' paper, we call for a paradigm shift to increase the impact of internet interventions toward the ultimate goal of improved population mental health. We propose four pillars for change: (1) increased focus on user-centered approaches, including both user-centered design of programs and greater individualization within programs, with the latter perhaps utilizing increased modularization; (2) Increased emphasis on engagement utilizing processes such as gaming, gamification, telepresence, and persuasive technology; (3) Increased collaboration in program development, testing, and data sharing, across both sectors and regions, in order to achieve higher quality, more sustainable outcomes with greater reach; and (4) Rapid testing and implementation, including the measurement of reach, engagement, and effectiveness, and timely implementation. We suggest it is time for researchers, clinicians, developers, and end-users to collaborate on these aspects in order to maximize the impact of e-therapies and serious gaming.

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