scholarly journals Lectin histochemical study of the quill sebaceous gland in the dorsal skin of the Sunda porcupine (Hystrix javanica)

2019 ◽  
Vol 20 (9) ◽  
Author(s):  
Andhika Yudha Prawira ◽  
SAVITRI NOVELINA ◽  
HUDA SALAHUDIN DARUSMAN ◽  
SRIHADI AGUNGPRIYONO ◽  
WARTIKA ROSA FARIDA

Abstract. Prawira AY, Novelina S, Farida WR, Darusman HS, Agungpriyono S. 2019. Lectin histochemical study of the quill sebaceous gland in the dorsal skin of the Sunda porcupine (Hystrix javanica). Biodiversitas 20: 2677-2684. In the Sunda Porcupine skin, the sebaceous glands of the quill follicles are multi-lobed alveolar and better developed than those of hair follicles. Using lectin histochemistry, we have studied the distribution of sugar-binding in the sebaceous glands of quills in comparison with those of hairs in six adult Sunda Porcupines. The skin samples from the thoracodorsal and lumbosacral regions were collected by biopsy procedure and processed for histology, histochemistry, and lectin histochemistry. The results showed that the lectin binding patterns are similar in secretory acinar parts of both types of sebaceous glands. The acini and excretory duct contained neutral carbohydrate and sugar residues. The acini also contained alpha D-mannose sugar residue, while the non-secretory excretory duct and debris in the lumen contained alpha-D-mannose, alpha-L-fucose, and α>β-N-acetylgalactosamine, and complex type N-glycan (oligosaccharide) sugar residues, as well. The present findings allowed us to suggest, that in Sunda Porcupine functions of the sebaceous glands of quills are more complex and active compared to those of the hairs.

Author(s):  
P. Dharani ◽  
T.A. Kannan ◽  
R. Gnanadevi ◽  
Geetha Ramesh ◽  
S. Balasubramanian ◽  
...  

Background: Madras Red sheep is a well-recognized meat type breed reared only on free range system to yield tasty meat. The aim of this study was to determine the gross, microanatomical and ultrastructural details of the interdigital gland in Madras Red sheep. Methods: The interdigital glands were removed immediately after slaughter and subjected for gross morphological, histological, immunohistochemical studies and ultrastructural observations. Result: The results revealed that a well-developed tobacco-pipe shaped interdigital gland was present in all the four limbs which was composed of an orifice, excretory duct, body and bent or flexure. Histologically, wall of the gland was composed of epidermis, dermis and capsule from within outward. Epidermis was made of stratified squamous keratinized epithelium. Dermis was composed of dense irregular connective tissue with sweat, sebaceous glands, arrectores pili muscle and hair follicles were embedded within. The sweat gland appeared as group of tortuous tubules under scanning electron microscope. The oily secretion of the gland helps in maintaining the healthiness of foot during movement of the animal.


1989 ◽  
Vol 93 (3) ◽  
pp. 315-321 ◽  
Author(s):  
Longqing Xia ◽  
Christos Zouboulis ◽  
Michael Detmar ◽  
Augusto Mayer-da-Silva ◽  
Rudolf Stadler ◽  
...  

1993 ◽  
Vol 67 (3) ◽  
pp. 179-188 ◽  
Author(s):  
T. Fujino ◽  
B. Fried

AbstractMouse (C3H) mucosal glycoconjugates were examined in normal small intestines and intestines infected with Echinostoma caproni, or E. trivolvis using six different fluorescein-conjugated lectins: Triticum, vulgaris agglutinin (WGA), Ulex europaeus agglutinin I (UEA-I), Ricinus communis agglutinin I (RCA-I). Glycine max soybean agglutinin (SBA), Dolichos biflorus agglutinin (DBA), and Arachis hypogaeu peanut agglutinin (PNA). The expression of lectin-binding sites and the intensity of the binding of lectins in the mouse small intestines were changed by infection with the echinostomes. Specific differences in the reaction to glycoproteins were clearly observed between the mouse intestines infected with E. caproni and those infected with E. trivolvis. In E. caproni infection, binding of most of the lectins to the villi was remarkably reduced in accord with the villous atrophy and loss of goblet cells. In contrast, in E. trivolvis infection, the binding of WGA, RCA-I and DBA was reduced in the microvillar surfaces, but binding of UEA-I and SBA were unchanged compared to the control intestines. The lectin binding to goblet cells in E. trivolvis-infected mice mostly increased. These observations may reflect the marked increase in goblet cells and the less severe damage in the villi of E. trivolvis infection compared to E. caproni infection. Most of the glycoconjugates were slightly reduced in the hyperplastic crypts except for N-acetyl glucosamine. It is possible that glucose metabolism in the host intestines infected with E. trivolvis was activated. resulting in an increase in the rate of mucin synthesis as well as qualitative changes in mucus, thereby mediating the expulsion of the worms.


Molecules ◽  
2020 ◽  
Vol 25 (16) ◽  
pp. 3697
Author(s):  
Tae-Kyeong Lee ◽  
Bora Kim ◽  
Dae Won Kim ◽  
Ji Hyeon Ahn ◽  
Hyejin Sim ◽  
...  

This current study investigates the facilitative effects and mechanisms of decursin, a major component of Angelica gigas Nakai (AGN), and AGN root extract on hair growth in mice. We perform high-performance liquid chromatography on AGN extract to show it contains 7.3% decursin. Hairs in mouse dorsal skin are shaved distilled in water, 0.15% decursin, and 2% AGN root extract (0.15% decursin in the diluted extract) and topically applied twice a day for 17 days. Hematoxylin and eosin staining are done to examine the morphological changes in the hair follicles. To compare the effects of decursin and AGN extract on inflammatory cytokines in the dorsal skin, Western blot analysis and immunohistochemistry for tumor necrosis factor α (TNF-α) and interleukin (IL)-1β as pro-inflammatory cytokines, and IL-4 and IL-13 as anti-inflammatory cytokines are conducted. The results show that the application of decursin and AGN extract confer effects on hair growth. Hair growth is significantly facilitated from seven days after the treatments compared to that in the control group, and completely grown hair was found 17 days after the treatments. The protein levels and immunoreactivity of TNF-α and IL-1β in this case are significantly decreased, whereas the IL-4 and IL-13 levels and immunoreactivity are significantly increased compared to those in the control group. Additionally, high-mobility group box 1, an inflammatory mediator, is elevated by the topical application of decursin and AGN extract. Taken together, the treatment of mouse dorsal skin with AGE root extract containing decursin promotes hair growth by regulating pro- and/or anti-inflammatory cytokines. We, therefore, suggest that AGN root extract as well as decursin can be utilized as materials for developing hair growth-facilitating treatments.


1989 ◽  
Vol 93 (3) ◽  
pp. 315-321 ◽  
Author(s):  
Longqing Xia ◽  
Christos Zouboulis ◽  
Michael Detmar ◽  
Augusto Mayer-da-Silva ◽  
Rudolf Stadler ◽  
...  

2014 ◽  
Vol 96 (3) ◽  
pp. 316-327 ◽  
Author(s):  
Laurie B. Joseph ◽  
Diane E. Heck ◽  
Jessica A. Cervelli ◽  
Gabriella M. Composto ◽  
Michael C. Babin ◽  
...  

2015 ◽  
Vol 7 (3) ◽  
pp. 358-362 ◽  
Author(s):  
Kazutoshi Harada ◽  
Yuichiro Kato ◽  
Yukihiko Kato ◽  
Ryoji Tsuboi

We herein report a case of hair follicle nevus, a rare hamartoma found on the face and showing follicular differentiation, which was associated with sebaceous hyperplasia. Dermoscopy of the lesion showed yellow globules surrounded by crown vessels/telangiectasias and scattered tiny hairs. Histopathological investigation revealed hyperplasia of the sebaceous glands and proliferation of well-differentiated vellus hair follicles. These pathological findings were thought to correspond to the yellowish globules and tiny hairs observed under dermoscopy. Hair follicle nevus associated with sebaceous hyperplasia is extremely rare; however, dermoscopic examination can suggest an appropriate diagnosis. The present case proved the diagnostic usefulness of dermoscopy for cutaneous tumors with hair follicular and sebaceous glandular differentiation.


2018 ◽  
Vol 3 (10) ◽  
Author(s):  
Alexa Green ◽  
Felicia Jefferson

Everyone wants shine, softness, and hair strength, all key factors in having healthy hair. The purpose of this literature review is to provide information about healthy hair growth. Research states that the hair grows from follicles within the skin. Hair follicles are sacs where hair grows and where the sebaceous glands open. The follicles lined by cells derived from the epidermal. Keratin protects epithelial cells from damage and it makes up the outer layer of human skin. Even though there are many ways you can grow your hair, there are many ways you can lose your hair as well. This review paper also explains disorders that can cause hair loss.


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