scholarly journals Necrotising fasciitis caused by metastatic endometrial cancer: a rare cause of a life-threatening condition

2017 ◽  
Vol 99 (2) ◽  
pp. e72-e74
Author(s):  
S Hendrickson ◽  
N Bystrzonowski ◽  
C Kokkinos ◽  
P Butler
Keyword(s):  
Risk Factors ◽  
Endometrial Cancer ◽  
Lumbar Spine ◽  
Endometrial Adenocarcinoma ◽  
Necrotising Fasciitis ◽  
Iliopsoas Muscle ◽  
Iliopsoas Abscess ◽  
Threatening Condition ◽  
Life Threatening ◽  
Common Risk Factors

We report a case of necrotising fasciitis caused by metastatic endometrial adenocarcinoma. Metastases to the lumbar spine with local invasion to the iliopsoas muscle led to an iliopsoas abscess, which subsequently progressed to necrotising fasciitis of the flank. This patient lacked common risk factors for necrotising fasciitis. There are no previous reports in the literature of necrotising fasciitis with this aetiology. We discuss the available evidence for aetiology of and risk factors for necrotising fasciitis, and the relation of time to surgery with prognosis.

Heterotopic pregnancy; case report

2019 ◽  
Vol 7 (05) ◽  
Author(s):  
Vipul R. Khandagale
Keyword(s):  
Risk Factors ◽  
Ectopic Pregnancy ◽  
Adnexal Mass ◽  
Heterotopic Pregnancy ◽  
Free Fluid ◽  
Threatening Condition ◽  
Life Threatening ◽  
Ectopic Pregnancies ◽  
High Index Of Suspicion ◽  
Low Risk Women

Heterotopic pregnancy is a rare clinical condition in which intrauterine and extrauterine pregnancies occur at the same time. It can be a life threatening condition and easily missed with the diagnosis. We present the case of a 37 year old patient who was treated for a heterotopic pregnancy with live intrauterine gestation and ruptured left adnexal gestation.The ectopic pregnancy was not suspected at her initial presentation. A high index of suspicion is needed in women with risk factors for an ectopic pregnancy and in low risk women who have free fluid with or without an adnexal mass with an intrauterine gestation.It is difficult to estimate exactly the incidence of ectopic pregnancies, but on an average it is approximately 1:300 normal pregnancies worldwide.

scholarly journals Aortic Dissection in a Pregnant Patient without Other Risk Factors

2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
Priya V. Patel ◽  
Raanan Alter ◽  
Recia Frenn ◽  
Thaddeus P. Waters
Keyword(s):  
Risk Factors ◽  
Aortic Dissection ◽  
Aortic Rupture ◽  
Treatment Options ◽  
Pregnant Patient ◽  
Physical Exam ◽  
Vascular Events ◽  
Increased Risk ◽  
Threatening Condition ◽  
Life Threatening

Background. An aortic dissection is a life-threatening condition in which the intima of the artery tears causing separation of the intima and media. Pregnancy places women at a significantly increased risk of common vascular events including venous thromboembolism, myocardial infarction, and stroke, while also increasing the risk of rarer vascular events such as aortic dissection and aortic rupture. Case. A 30-year-old previously healthy multiparous woman presenting at 36 weeks of pregnancy with a Type A aortic dissection. She underwent a combined emergent cesarean delivery followed by repair of her aortic root. Conclusions. Aortic dissection should be high on the differential for pregnant patients presenting with the characteristic complaints and physical exam findings given the high mortality rate associated with this vascular event. Teaching Points. (1) This report reviews the characteristic presentation, risk factors, and physical exam findings in a patient with an aortic dissection. (2) The report includes treatment options for pregnant patients based on the classification of the dissection.

scholarly journals A Case of Unilateral Coccidioidal Chorioretinitis in a Patient with HIV-Associated Meningoencephalitis

2019 ◽  
Vol 2019 ◽  
pp. 1-3 ◽  
Author(s):  
Christopher B. Toomey ◽  
Andrew Gross ◽  
Jeffrey Lee ◽  
Doran B. Spencer
Keyword(s):  
Risk Factors ◽  
Vision Loss ◽  
Complement Fixation ◽  
Rare Condition ◽  
Threatening Condition ◽  
Life Threatening ◽  
History Of ◽  
Blurry Vision ◽  
Systemic Symptoms ◽  
The Right

Intraocular coccidioidomycosis is a rare condition, with the most commonly reported presentation being an idiopathic iritis in patients who live in or have traveled thorough endemic areas. A paucity of reports exists describing the chorioretinal manifestations of coccidioidomycosis. Here we report a case of unilateral coccidioidal chorioretinitis and meningoencephalitis in an AIDS patient that led to near complete unilateral loss of vision. A 48-year-old Hispanic female with poorly controlled HIV/AIDS in southern California presented with a three-week history of headache, nausea, vomiting, right eye blurry vision, and a one-day history of subjective fever. Examination of the right eye revealed vitritis and several large chorioretinal lesions scattered throughout the periphery and macula with optic disc pallor. Serum coccidioidomycoses complement fixation (CF) was positive (titers of 1 : 256). Neuroimaging revealed a new area of enhancement in the left anterior frontal lobe consistent with meningoencephalitis. The patient was treated with intravenous fluconazole and intravitreal voriconazole with resolution of systemic symptoms and vitritis but persistence of unilateral, severe chorioretinal scarring and vision loss. In conclusion, in spite of the rarity of intraocular coccidioidomycosis, one must carry a degree of suspicion for this vision- and life-threatening condition as a potential etiology of chorioretinitis in individuals with pertinent risk factors.

scholarly journals Colic in the British military working horse population: a retrospective analysis

2018 ◽  
Vol 184 (1) ◽  
pp. 24-24
Author(s):  
Victoria J Tannahill ◽  
Jacqueline M Cardwell ◽  
Tom H Witte
Keyword(s):  
Risk Factors ◽  
Population Data ◽  
Horse Population ◽  
Multiple Risk Factors ◽  
British Military ◽  
Incidence And Mortality ◽  
Threatening Condition ◽  
Life Threatening ◽  
Intensively Managed ◽  
Careful Management

Colic is a common and potentially life-threatening condition of horses. Multiple risk factors have been previously identified and it is known that a careful management routine can help reduce colic rates. The British military working horse population represents a unique cohort of horses that are intensively managed with a strict regimen. This retrospective study examined the incidence and mortality rate of colic within this population, as well as the signalment of affected horses, and compared these with the general population. Data for 717 horses over a five-year period (2008–2012) were analysed. Of these, 163 horses (22.7 per cent) experienced 267 colic episodes and 13 horses (1.8 per cent) died because of colic. Recurrent colic was experienced by 35 per cent (57/163) of horses. The incidence of colic was 11.1 episodes per 100 horse-years and of colic-related death was 0.5 deaths per 100 horse-years. Horses purchased from mainland Europe were more likely to suffer from colic (OR 4.6; P<0.001) and from recurrent colic (OR 6.0; P=0.005) than horses purchased from Ireland. Only 3 per cent (8/267) of colic episodes were treated surgically. It was concluded that the incidences of colic and colic-related deaths within the British military working horse population are similar to those of the general horse population.

Finegoldia magna: a rare cause of necrotising fasciitis

2020 ◽  
Vol 13 (5) ◽  
pp. e235115
Author(s):  
Ardit Begaj ◽  
Ross C McLean ◽  
Pudhupalayam Bhaskar
Keyword(s):  
Soft Tissues ◽  
Necrotising Fasciitis ◽  
Normal Flora ◽  
Native Valve ◽  
Skin Changes ◽  
Native Valve Endocarditis ◽  
Threatening Condition ◽  
Life Threatening ◽  
Severe Infections ◽  
Uncommon Case

Necrotising fasciitis is a life-threatening condition characterised by inflammation, affecting the soft tissues, which spreads within a fascial plane. Skin changes can be delayed and can often go unnoticed. The condition arises from a bacterial infection, commonly being of polymicrobial aetiology. We describe an uncommon case of necrotising fasciitis caused by Finegoldia magna, an anaerobic coccus, in a 40-year-old patient with diabetes. F. magna is a Gram-positive anaerobic coccus, which was previously known as Peptostreptococcus magnus. The bacteria is found in the normal flora of the urogenital tract. The bacteria is associated with severe infections such as native valve endocarditis, paravalvular abscess around a bioprosthetic valve, purulent pericarditis complicated by mediastanitis, meningitis after pneumonia and necrotising pneumonia complicated by pyopneumothorax. There have been no cases in the literature describing necrotising fasciitis of the abdominal wall caused by F. magna.

Catastrophic antiphospholipid syndrome presenting with aortic barrage: case report and review of the literature

Lupus ◽  
2021 ◽  
Vol 30 (6) ◽  
pp. 1005-1009
Author(s):  
Luca Moroni ◽  
Paolo Righini ◽  
Giuseppe A Ramirez ◽  
Nicola Farina ◽  
Gaia Mancuso ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Report ◽  
Antiphospholipid Syndrome ◽  
Unusual Case ◽  
Thromboembolic Events ◽  
Review Of The Literature ◽  
Catastrophic Antiphospholipid Syndrome ◽  
Short Period ◽  
Threatening Condition ◽  
Life Threatening

Catastrophic antiphospholipid syndrome (CAPS) is a life-threatening condition characterized by multiple thromboembolic events occurring in a short period of time, frequently accompanied by significant systemic inflammation. Aortic involvement is rare in antiphospholipid syndrome and it had been never described in the context of its catastrophic variant. Here, we report an unusual case of aortic occlusion as a debut manifestation of CAPS and discuss its clinical features with an up-to-date review of the literature to identify risk factors and clues for clinical practice.

scholarly journals Repeated Sepsis in an 83-Year-Old Man With Cancer With Long-Lasting Invasive Treatments

2020 ◽  
Author(s):  
Masoomeh Imanipour ◽  
Nasrin Rasoulzadeh ◽  
Amin Hosseini
Keyword(s):  
Risk Factors ◽  
Immune Response ◽  
Immune System ◽  
Antibiotic Therapy ◽  
Major Trauma ◽  
Fluid Replacement ◽  
Underlying Condition ◽  
Threatening Condition ◽  
Life Threatening ◽  
Inflammatory Immune Response

Sepsis is a life-threatening condition that arises when the body's response to infection damages its own tissues and organs. Sepsis is caused by an inflammatory immune response triggered by an infection. Its risk factors include aging, weak immune system, major trauma, or burns. Treatment of sepsis is often based on fluid replacement and antibiotic therapy. In this study, an 83-year-old man is reported with two times of diagnosis of sepsis during three years. The first sepsis was due to an infection of the colostomy and the second one followed an infection at tracheostomy site. It seems that the disease and the underlying condition of the patient contribute to the occurrence of sepsis. The patient each time was discharged from the hospital after successful response to the treatment

Methicillin-resistant Staphylococcus aureus (MRSA) submandibular abscess in a neonate

2021 ◽  
Vol 14 (5) ◽  
pp. e242258
Author(s):  
Natalia Glibbery ◽  
Theodore Gouliouris ◽  
Jessica Bewick
Keyword(s):  
Risk Factors ◽  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Complex Case ◽  
Airway Compromise ◽  
Methicillin Resistant ◽  
Life Threatening ◽  
Common Risk Factors ◽  
Male Neonate ◽  
Prompt Diagnosis

Neonatal suppurative submandibular sialadenitis and abscess formation is an exceedingly rare entity. This report describes a complex case of a male neonate with a methicillin-resistant Staphylococcus aureus (MRSA) submandibular abscess, requiring emergency intubation due to acute airway compromise. The patient was admitted to the paediatric intensive care unit, received appropriate antibiotic treatment and underwent urgent surgical drainage of the abscess. He made a full recovery and remains well 18 months later. No comorbidities or common risk factors for the disease were identified. Although extremely uncommon, neonatal submandibular abscesses can lead to significant morbidity. Neonates tend to present insidiously, and sudden clinical deterioration with airway compromise is possible. MRSA has been increasingly implicated in these infections, even in the absence of relevant risk factors. As such, continued clinical vigilance is essential for prompt diagnosis and prevention of life-threatening complications. Multidisciplinary input is paramount for appropriate management of these complex infections.

scholarly journals Ectopic Pregnancy, Still A Life Threatening Emergency - A Clinical Study Of 100 Cases

2014 ◽  
Vol 2 (1) ◽  
Author(s):  
Kavitha B ◽  
Geetha L ◽  
Usha Rani T ◽  
Rama Devi A ◽  
Madhuri K ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ectopic Pregnancy ◽  
Case Fatality ◽  
Common Life ◽  
Ectopic Gestation ◽  
Child Bearing ◽  
Life Threatening ◽  
Common Risk Factors ◽  
A Prospective Study ◽  
Urine Pregnancy Test

Ectopic pregnancy is still a major challenge & its incidence is on the rise due to changes in lifestyle & advances in medical practice. The objective was to study incidence, clinical presentation, risk factors & management of cases that presented in our hospital over a four -year period. A Prospective study of 100 cases presenting as ectopic pregnancy from 15-1-2010 to 15-1-2014.During this period total of 3176 deliveries & 1347 gynaecological surgeries were recorded. 100 patients had ectopic gestations accounting for 3.1% of all deliveries & 7.4% of gynaecological surgeries. Peak age group was 20-29y in 59cases(59%). Gestational age at presentation was 6-8weeks for most of the cases (62%). 59 cases (59%) were multiparous & 41(41%) were nulliparous. All had symptoms suggestive of ectopic pregnancy (amenorrhea, abdominal pain, giddiness, bleeding pervaginum). Diagnosis was confirmed by urine pregnancy test & USG. Common risk factors present were previous surgery ie LSCS-30(30%), Tubectomy-19(19%); Abortions-32(32%); Infertility-36(36%); PID-16(16%).Out of 100cases, 93 (93%) were ruptured & 7(7%) unruptured. Unruptured cases were treated medically using Methotrexate. Laparotomy was done for ruptured cases. Commonest site of Ectopic was ampulla (60%). Salpingectomy was done for most cases (73%).Although case-fatality has decreased, ruptured Ectopic gestation continues to be a common life-threatening emergency making tubal conservation inapplicable. This is of concern in a society with high premium on child-bearing.

scholarly journals Attitude and practice of smoking among adolescent

2018 ◽  
Vol 8 (2) ◽  
pp. 57-62
Author(s):  
Sabina Shrestha ◽  
Sarita Panta
Keyword(s):  
Risk Factors ◽  
Cigarette Smoking ◽  
Secondary School ◽  
Exploratory Study ◽  
Negative Attitude ◽  
Attitude And Practice ◽  
Threatening Condition ◽  
Life Threatening ◽  
Self Administered Questionnaire ◽  
Day By Day

Adolescence is the time between the beginning of sexual maturation and adulthood and considered to be the period between ages 12 and 19. Smoking becomes the major risk factors for various disease and life threatening condition. The numbers of smokers are increasing day by day due to varieties of influencing factors. Therefore, a study was conducted with the objective of identifying the attitude and practice of smoking among adolescent. Descriptive exploratory study design was used to identifying the attitude and practice of smoking among adolescent towards Niharika Shishu Kunja Secondary school, Bypass, Kathmandu. Data was collected using semi structured self-administered questionnaire from 68 students studying in Niharika Shishu Kunja Secondary school. Non-probability purposive sampling was used. This study revealed that All most all (95.6%) of respondents had negative attitude towards cigarette smoking. Majority (69.1%) of respondents were non- smoker whereas 30.9% were smoker. The study concludes that adolescents were influenced to have cigarette with curiosity and experimentation with the companionship of friends.

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