scholarly journals Absent Bilateral Upper Limb Pulses in Middle Age Male? Takayasu Arteritis

2020 ◽  
Vol 6 (3) ◽  
Keyword(s):  
Blood Pressure ◽  
Gall Bladder ◽  
Upper Limb ◽  
Takayasu Arteritis ◽  
Middle Age ◽  
Anesthetic Management ◽  
Age Group ◽  
Pulseless Disease ◽  
Female Predominance ◽  
Large Vessels

Takayasu arteritis also termed as pulseless disease is a rare and chronic inflammatory arteritis of large vessels. It is manifested mainly in young age group between 10-40 years with a female predominance. Anesthetic management of these patients is challenging in view of fluctuation in blood pressure, intimal fibrosis and stenosis of major blood vessels and multiorgan involvement. Here we present a case of 55 year old male patient with bilateral absent upper limb pulses posted for emergency surgery in view of gall bladder perforation that was successfully managed under general anesthesia. Keywords: Takayasu; Chronic; Inflammatory.

scholarly journals Karşıyaka Prevalance and Awareness of Hypertension Study (KARHIP)

2016 ◽  
Vol 8 ◽  
Author(s):  
Nihat Pekel ◽  
Mehmet Emre Özpelit ◽  
Ebru Özpelit ◽  
Serkan Yakan ◽  
Caner Topaloğlu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Middle Age ◽  
Blood Pressure Measurement ◽  
Field Work ◽  
National Average ◽  
Composition Analysis ◽  
Age Group ◽  
Average Systolic Blood Pressure ◽  
Hypertension Prevalence ◽  
Hypertension Awareness

<p><strong>Background: </strong>The study<strong> </strong>was planned to assess potential differences in hypertension prevalance and hypertension related demographic properties in a urban area with relatively higher income and cultural population compared to national average. <strong>Methods: </strong>Field work was done by educated personel at Karşıyaka Municipality Building by one by one interviewing poll, blood pressure measurement, rhythm and body composition analysis in February 2014. Hypertension was defined as  average  systolic blood pressure ≥140 mmHg or  average diastolic blood pressure ≥90 mmHg. <strong>Results: </strong>Out of total 1417 (627 males and 790 females) people enrolled, 780 people hypertensive(prevalence 55%). Hypertension prevalence in middle age group( age 35-65) was 46%, in geriatric age group(age&gt;65) %79. 216 out of 780 hypertensive  (27.7%) people were not aware of their disease. Ratio of people under antihypertensive treatment was 69.4% and ratio of people under control was 34.7%, whereas control rate was 50.1% in 541 patients who were aware of their diseases.<strong>Conclusions: </strong>Hypertension prevalances in our study were similar to PatenT2 trial prevalances, which were  46 % for middle age group and 78% for geriatric age group. Compared to PatenT 2 data, rate of hypertension awareness (54.7% vs 72.3%) and rate of being under treatment (47.5% vs 69.4%) were higher. Rate of controlled hypertension was a little big higher (28.7 % vs 34.7% )in our group, whereas  control rates  in aware and treated groups were similar (53.9 % and 50.1 %) in both study. <strong>Keywords: </strong>Hypertension, Prevalance, Awareness, Treatment</p><p> </p>

scholarly journals Effect of Aging on Short Term Heart Rate Variability

2015 ◽  
Vol 9 (2) ◽  
pp. 78-82 ◽  
Author(s):  
Qazi Farzana Akhter ◽  
Qazi Shamima Akhter ◽  
Farhana Rohman ◽  
Susmita Sinha ◽  
Sybilla Ferdousi
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Healthy Subjects ◽  
Middle Age ◽  
Older Age ◽  
Autonomic Nerve ◽  
Age Group ◽  
Nerve Function ◽  
Autonomic Nerve Function

Background: Heart rate variability has been considered as an indicator of autonomic nerve function status. Few works have been done to assess the heart rate variability in normal healthy subjects in different countries. Objectives: To assess the cardiac autonomic nerve function status in healthy Bangladeshi population of different age groups by analyzing time domain measures of Heart Rate Variability. Methods: This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from the period of July 2012 to June 2013. For this purpose, a total number of 180 healthy subjects were selected with the age ranging from 15-60 years of both sexes. All the study subjects were divided into 3 different groups according to age (Control 15-30 years; middle age 31-45 years; older age 46-60 years). Each group included 60 subjects of which 30 were male and 30 were female. The subjects were selected from different areas of Dhaka city by personal contacts. HRV parameters were recorded by a 4 active channels, RMS Polyrite-D-2 machine For statistical analysis, one way ANOVA, unpaired Student’s ‘t’-test and Pearson’s correlation coefficient test were performed. as applicable. Results: Systolic blood pressure (SBP), diastolic blood pressure (DBP) were significantly (p<0.001) higher in older group in comparison to control & middle age group. Again RR interval and RMSSD (p<0.001), were significantly lower in older age group (p<0.05) compared to control & also to middle age group. But HR was found significantly higher (p<0.05)in both middle and older subjects than control and also in older (p<0.05) compared to middle age. Correlation analysis showed moderate negative correlation of mean R-R with age in middle age whereas significant negative correlation for RMSSD both in middle and older age subjects. Conclusion: In this study, markedly decreased cardiac parasympathetic function were found with aging process. DOI: http://dx.doi.org/10.3329/jbsp.v9i2.22801 Bangladesh Soc Physiol. 2014, December; 9(2): 78-82

Takayasu arteritis presenting with malignant hypertension; a rare manifestation of a rare disease: a case report and review of the literature

2016 ◽  
Vol 47 (1) ◽  
pp. 60-63 ◽  
Author(s):  
Bhupeshwari Patel ◽  
Astha Tiwari ◽  
Shiv Ram Krishna Dubey ◽  
Girish C Bhatt ◽  
Punit Tiwari ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Takayasu Arteritis ◽  
Surgical Intervention ◽  
Blood Pressure Monitoring ◽  
Malignant Hypertension ◽  
Pressure Monitoring ◽  
Rare Manifestation ◽  
Paediatric Age ◽  
Large Vessels

Takayasu arteritis (TA) is a chronic inflammatory and obliterative disease of large vessels, which mainly affects the aorta and its major branches. TA can lead to renal failure and renovascular hypertension in 60% of patients; it is rare in children aged <10 years and, more rarely, it presents with malignant hypertension in the paediatric age group. Here we present a case of 9-year-old boy with TA who presented with malignant hypertension and required surgical intervention to control the blood pressure. Subsequently, his medications were titrated using 24 h ambulatory blood pressure monitoring (ABPM) and is doing well on follow-up.

scholarly journals Catching Takayasu Early: Diagnosing the “Pulseless” Disease in a Child with Palpable Pulses

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
A. R. Santosh Rao ◽  
Vinay Jahagirdar ◽  
Kaanthi Rama
Keyword(s):  
Takayasu Arteritis ◽  
Systemic Vasculitis ◽  
Celiac Artery ◽  
Lower Limbs ◽  
Sustained Remission ◽  
Pulseless Disease ◽  
The Third ◽  
Long Term Prognosis ◽  
Large Vessels

Takayasu arteritis is a systemic vasculitis of large vessels that mainly involves the aorta and its branches. It normally presents in the third decade of life and is rarely seen in children. We report a case of childhood Takayasu arteritis, in a 12-year-old girl, who presented with abdominal pain and hypertension. Although all her peripheral pulses were palpable, there was a discrepancy between her upper and lower limbs’ blood pressure. CT angiography revealed stenosis of the abdominal aorta, at the origin of the celiac artery and right renal artery. She was started on steroids and an antihypertensive, after which she attained remission. Five years down the line, the child has sustained remission, with no signs of disease progression. Early diagnosis of Takayasu and initiation of immunosuppression, before the onset of the classic “pulseless” phase, may contribute to improved long-term prognosis.

scholarly journals Takayasu Arteritis Involving Multiple Peripheral Arteries of a 37-year-old Female: A Case Report and Brief Overview

2016 ◽  
Vol 30 (2) ◽  
pp. 92-95
Author(s):  
Md Faruque ◽  
MA Rashid ◽  
Md Tanveer Faruk ◽  
Md Jabed Iqbal ◽  
F Rahman
Keyword(s):  
Takayasu Arteritis ◽  
Invasive Procedure ◽  
Rare Condition ◽  
Modern Technology ◽  
The Body ◽  
Vascular Involvement ◽  
Asian Women ◽  
Pulseless Disease ◽  
Exertional Angina ◽  
Large Vessels

Takayasu arteritis, formerly known as “pulseless disease”, is a chronic idiopathic vasculitis which affects the large vessels in the body. First described in the 1800’s, this rare condition is more commonly found in Asian women in their 40’s. Herein, we report the case of a young woman whose exertional angina and claudication were the initial presentation of active Takayasu arteritis. The importance of modern technology of imaging such as CT, MRI and angiography, can often have paramount importance for confirming a diagnosis and the extent of the pathology. Newer modalities of investigation helps in evaluation of vascular involvement and its haemodynamic effects on cardiovascular system. Previously majority of patient had to be diagnosed clinically. Now a days by CT peripheral Angiogram this disease can be diagnosed. Invasive procedure of peripheral Angiogram is troublesome but single IV dye injection can revealed the actual scenario. So it has got important scientific value.Bangladesh Heart Journal 2015; 30(2) : 92-95

scholarly journals Is there an association between upper limb claudication and handgrip strength in Takayasu arteritis?

Reumatismo ◽  
2021 ◽  
Vol 72 (4) ◽  
pp. 197-206
Author(s):  
A.M. Dos Santos ◽  
R.G. Misse ◽  
I.B.P. Borges ◽  
R.M.R. Pereira ◽  
S.K. Shinjo
Keyword(s):  
Blood Pressure ◽  
Upper Limb ◽  
Functional Capacity ◽  
Takayasu Arteritis ◽  
Handgrip Strength ◽  
Hand Strength ◽  
Clinical Activity ◽  
Physician Global Assessment ◽  
Vessel Imaging ◽  
Left Limb

Limb vascular claudication and hand muscle weakness are common symptoms of Takayasu arteritis (TAK). However, no studies have correlated these two symptoms. Therefore, the aim of the study was to evaluate handgrip strength and its correlation with both upper-limb vascular claudication and imaging of the vessels. This cross-sectional study compared 36 patients with TAK who were matched by age, gender, and body mass index with 36 individuals without TAK (CTR). Hand strength (assessed with handgrip dynamometer), functional capacity (Health Assessment Questionnaire, HAQ), upper-limb vascular claudication symptoms (patients’ selfreported form), and disease activity (Indian Takayasu Clinical Activity Score [ITAS] 2010; Physician Global Assessment [PGA], C-reactive protein, and erythrocyte sedimentation rate) were evaluated as well as vessel imaging (e.g., angiotomography or angioresonance) and blood pressure. The median age of the patients was 42.0 years (35.5-51.5 years), whereas the mean disease duration was 13.1±6.8 years. No patient had active disease. Compared to the CTR, the patients with TAK showed reduced strength in the left-hand (22.9±5.9 vs 26.3±5.6 kg; p=0.014) and increased HAQ scores [0.50 (0.12-0.87) vs 0.00 (0.00-0.00); p<0.001]. Both groups had comparable blood pressure. Among patients with TAK, lefthand strength was inversely correlated with HAQ (Spearman correlation: rho=–0.584; p<0.001) and positively correlated with right-hand strength (rho=0.644; p<0.001). Moreover, neither hand’s strengths in the patients were correlated with subclavian stenosis imaging, blood pressure or limb vascular claudication. The reduction of strength in the upper left limb is inversely related to the functional capacity (HAQ score) of TAK. This reduction appears unrelated to classical vascular claudication, vessel imaging or blood pressure.

Influence of Ageing and Regional Differences on Draught Performance of Umblachery Cattle

2019 ◽  
Vol 15 (02) ◽  
pp. 42-45
Author(s):  
Devi M Kousalya ◽  
S.M K Karthickeyan ◽  
R Venkataramanan ◽  
S N Sivaselvam ◽  
K G Tirumurugaan
Keyword(s):  
Pulse Rate ◽  
Power Output ◽  
Regional Differences ◽  
Stride Length ◽  
South India ◽  
Middle Age ◽  
Age Group ◽  
Morphometric Traits ◽  
Maximum Power Output ◽  
Effects Of Aging

An attempt was made to assess the effects of aging, regional differences, and draught load applied on draught potential of Umblachery cattle, an important draught breed of South India. Age had a highly significant effect (p less than 0.01) on all morphometric traits, stride length, and significant effect (p less than 0.05) on pulse rate after work. The middle age group (5.0 to 7.5 years) with more substantial stride length was identified as the critical productive age group for draught ability. Regional differences had a highly significant (p less than 0.01) influence on stride length, horsepower, and a significant effect (p less than 0.05) on pulse rate after work. The optimum draught load with which Umblachery breed could give uniform and maximum power output was found to be around 75 to 78 kg.

Elevation of pulse pressure in middle age is associated with the risk of dementia: data from a population-based cohort

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
D Kim ◽  
H Jung ◽  
P.S Yang ◽  
H.T Yu ◽  
T.H Kim ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Pulse Pressure ◽  
Middle Age ◽  
Population Based ◽  
Entire Cohort ◽  
Incident Dementia ◽  
Increased Risk ◽  
Diagnosis Of Dementia ◽  
History Of ◽  
The Mean

Abstract Aims Pulse pressure (PP) is a well-known risk factor for cardiovascular disease. However, the association between the PP and dementia is not well identified. This study aimed to determine the effect of PP on the risk of dementia development in different age subgroups using a longitudinal, population-based, and stroke-free cohort from the general population. Methods The association of PP with the development of incident dementia was assessed from January 1, 2005, to December 31, 2013, in 433,154 participants without a history of dementia or stroke from the Korea National Health Insurance Service-Health Screening cohort. The diagnosis of dementia was defined using the 10th revision of the International Classification of Disease codes. Results The mean age of the cohort was 55.7±9.2 years, 45.7% were women. Hypertension was 23.6%. The mean systolic and diastolic blood pressure of the entire cohort were 125.9±16.6 and 78.4±10.7 mmHg, respectively. Mean PP was 47.5±10.9 mmHg. In the middle-age group (40 to 50 year-old), increasing of 10 mmHg of PP was associated with incident dementia after adjusting mean blood pressure and clinical variables with a hazard ratio (HR) of 1.21 (95% confidence interval [CI]: 1.19–1.23, p&lt;0.001). The association was still significant even after censoring for stroke (HR: 1.16, 95% CI: 1.08–1.22, p&lt;0.001). In the older population, elevation of PP was not associated with dementia development (HR: 0.98, 95% CI: 0.95–1.01, p=0.247) Conclusion PP was associated with increased risk of dementia only in middle-aged population beyond that of mean arterial pressure. Funding Acknowledgement Type of funding source: None

scholarly journals POS0815 CLINICAL CHARACTERISTICS, IMAGING PHENOTYPE, AND LONG-TERM OUTCOMES OF TAKAYASU ARTERITIS PATIENTS WITH HYPERTENSION

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 661.1-661
Author(s):  
Y. Sun ◽  
L. Ma ◽  
H. Chen ◽  
C. Rongyi ◽  
L. Jiang
Keyword(s):  
Blood Pressure ◽  
Adverse Events ◽  
Clinical Features ◽  
Takayasu Arteritis ◽  
Pressure Control ◽  
Free Survival ◽  
The World ◽  
Cluster 2

Background:Hypertension occurred in 30-80% of TAK patients around the world. The occurrence of hypertension might severely worsen TAK prognosis. Nevertheless, data describing the specific imaging features in hypertensive TAK patients and the associations between hypertensive severity, blood pressure control status and long-term outcome were still lacking.Objectives:To investigate the characteristics and associations of hypertensive characteristics with adverse events-free survival in Takayasu arteritis (TAK) patients with hypertension.Methods:This research was based on a prospectively on-going observational cohort-East China Takayasu Arteritis (ECTA) cohort. In all, 618 TAK patients, who registered in the ECTA cohort up to December 2019, were enrolled. The main outcome was the adverse-events-free survival among hypertensive TAK patients during the follow-up ended on August 2020.Results:Totally, 204 (33.0%) patients suffered from hypertension, with 48 (23.5%), 62 (30.4%), and 94 (46.1%) mild, moderate, and severe hypertension, respectively. Cluster analysis indicated three imaging phenotypes for hypertensive TAK patients: Cluster 1: involvement of the abdominal aorta and/or renal artery (n=56, 27.5%); Cluster 2: involvement of the ascending aorta, thoracic aorta, and the aortic arch and its branches (n=38, 18.6%); Cluster 3: combined involvement of Cluster 1 and Cluster 2 (n=111, 54.4%). By the end of the follow-up, the blood pressure control rate was 50.8%, while the adverse-events-free survival was 67.9% in the entire hypertensive population. Multivariate Cox regression analysis indicated that well-controlled blood pressure (HR=2.13, 95%CI 1.32–3.78, p=0.047), co-existence of severe aortic valve regurgitation (HR=0.87, 95%CI 0.64–0.95, p=0.043), Cluster 1 (HR=0.69, 95%CI 0.48–0.92, p=0.017) and Cluster 3 (HR=0.72, 95%CI 0.43–0.94, p=0.048) imaging phenotype was associated with the adverse-events-free survival.Conclusion:Patients with controlled hypertension showed better adverse-events-free survival, while those with the Cluster 1 imaging phenotype were more likely to suffer from worse adverse-events-free survival. Hypertension occurred in 30-80% of TAK patients around the world. The occurrence of hypertension might severely worsen TAK prognosis.References:[1]Johnston SL, Lock RJ, Gompels MM. Takayasu arteritis: a review. J Clin Pathol 2002; 55:481–6.[2]Watanabe Y, Miyata T, Tanemoto K. Current clinical features of new patients with Takayasu arteritis observed from a cross-country research in Japan: age and sex specificity. Circulation 2015; 132:1701–9.[3]Yilmaz N, Can M, Oner FA, et al. Impaired quality of life, disability and mental health in Takayasu’s arteritis. Rheumatol. (Oxford) 2013; 52:1898–904.[4]Laurent A, Julien H, Nicolas L, et al. Takayasu arteritis in France: a single-center retrospective study of 82 cases comparing white, North African, and black patients. Medicine 2010; 89:1–17.[5]Mwipatayi BP, Jeffery PC, Beningfield SJ, et al. Takayasu arteritis: clinical features and management: report of 272 cases. ANZ J Surg 2005; 75:110–7.Disclosure of Interests:None declared

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