scholarly journals The Mechanism of Antifungal Action of Essential Oil from Dill (Anethum graveolens L.) on Aspergillus flavus

PLoS ONE ◽  
2012 ◽  
Vol 7 (1) ◽  
pp. e30147 ◽  
Author(s):  
Jun Tian ◽  
Xiaoquan Ban ◽  
Hong Zeng ◽  
Jingsheng He ◽  
Yuxin Chen ◽  
...  
Keyword(s):  
Essential Oil ◽  
Aspergillus Flavus ◽  
Anethum Graveolens ◽  
Antifungal Action

Antifungal mechanism of essential oil from Anethum graveolens seeds against Candida albicans

2013 ◽  
Vol 62 (8) ◽  
pp. 1175-1183 ◽  
Author(s):  
Yuxin Chen ◽  
Hong Zeng ◽  
Jun Tian ◽  
Xiaoquan Ban ◽  
Bingxin Ma ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Plasma Membrane ◽  
Essential Oil ◽  
Flow Cytometric Analysis ◽  
Ros Production ◽  
Anethum Graveolens ◽  
Antifungal Mechanism ◽  
Ros Accumulation ◽  
Ergosterol Synthesis ◽  
Antifungal Action

This work studied the antifungal mechanism of dill seed essential oil (DSEO) against Candida albicans. Flow cytometric analysis and inhibition of ergosterol synthesis were performed to clarify the mechanism of action of DSEO on C. albicans. Upon treatment of cells with DSEO, propidium iodide penetrated C. albicans through a lesion in its plasma membrane. DSEO also significantly reduced the amount of ergosterol. These findings indicate that the plasma membrane of C. albicans was damaged by DSEO. The effect of DSEO on the functions of the mitochondria in C. albicans was also studied. We assayed the mitochondrial membrane potential (mtΔψ) using rhodamine 123 and determined the production of mitochondrial dysfunction-induced reactive oxygen species (ROS) via flow cytometry. The effects of the antioxidant l-cysteine (Cys) on DSEO-induced ROS production and the antifungal effect of DSEO on C. albicans were investigated. Exposure to DSEO increased mtΔψ. Dysfunctions in the mitochondria caused ROS accumulation in C. albicans. This increase in the level of ROS production and DSEO-induced decrease in cell viability were prevented by the addition of Cys, indicating that ROS are an important mediator of the antifungal action of DSEO. These findings indicate that the cytoplasmic membrane and mitochondria are the main anti-Candida targets of DSEO.

Chemical Composition and Active Properties Evaluation of Wild Oregano (Origanum Vulgare) and Ginger (Zingiber Officinale-Roscoe) Essential Oils

2018 ◽  
Vol 69 (8) ◽  
pp. 1927-1933 ◽  
Author(s):  
Mariana Deleanu ◽  
Elisabeta E. Popa ◽  
Mona E. Popa
Keyword(s):  
Essential Oil ◽  
Growth Inhibition ◽  
Gallic Acid ◽  
Aspergillus Flavus ◽  
Zingiber Officinale ◽  
Penicillium Expansum ◽  
Origanum Vulgare ◽  
Zingiber Officinale Roscoe ◽  
Oregano Oil ◽  
Gallic Acid Equivalent

The compounds in Ginger (Zingiber officinale-Roscoe) essential oil provenience China and wild oregano (Origanum vulgare) essential oil of Romanian origin were identified by GC/MS and their antioxidant and antifungal properties were evaluated. Wild oregano oil was characterized by high content of oxygenated monoterpenes hydrocarbons (84.05%) of which carvacrol was the most abundant (73.85%) followed by b-linalool (3.46%) and thymol (2.29%). Ginger oil had a higher content of sesquiterpene hydrocarbons including zingiberene (31.47%), b-sesquiphellandrene (13.76%), a-curcumene (10.41%), a-farnesene (8.31%) and b-bisabolene (7.55%) but a lower content of oxygenated monoterpenes (7.97%). The high content of oxygenated monoterpens of wild oregano oil is in accordance with total content of polyphenols determined by the Folin�Ciocalteu method (6.71�0.73 mg of gallic acid equivalent per g oil). Ginger oil had only 1.34�0.22 mg gallic acid equivalent per g oil. Wild oregano oils exhibited appreciable in vitro antioxidant activity as assessed by 2, 2`-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and 2,2�-azino-bis (3 ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS). The sample concentration required to scavenge 50% of the DPPH free radicals was 0.76�0.13 mg/mL for wild oregano oil compared to 20.22�2.12 mg/mL for ginger oil. Also, wild oregano oils showed significant inhibitory activity against selected pathogenic fungi (Fusarium oxysporum, Aspergillus flavus and Penicillium expansum). 1�L of oregano oil is sufficient for almost 75% growth inhibition of Aspergillus flavus compared to ginger oil which shows antifungal activity at 240�L for 78% growth inhibition. It can be concluded that wild oregano oil could be used as food preservative in some food products in which Fusarium oxysporum, Aspergillus flavus and Penicillium expansum could grow and have potential to produce health hazards mycotoxines.

scholarly journals Effectiveness of topical administration of Anethum graveolens essential oil on MRSA-infected wounds

2019 ◽  
Vol 109 ◽  
pp. 1650-1658 ◽  
Author(s):  
Reza Manzuoerh ◽  
Mohammad Reza Farahpour ◽  
Ahmad Oryan ◽  
Ali Sonboli
Keyword(s):  
Essential Oil ◽  
Topical Administration ◽  
Anethum Graveolens ◽  
Infected Wounds

scholarly journals Antifungal action of Lippia alba essential oil in Rhizoctonia solani disease management

2019 ◽  
Vol 1 (10) ◽  
Author(s):  
Arvind Saroj ◽  
C. S. Chanotiya ◽  
Ranjana Maurya ◽  
V. S. Pragadheesh ◽  
Anju Yadav ◽  
...  
Keyword(s):  
Disease Management ◽  
Essential Oil ◽  
Rhizoctonia Solani ◽  
Lippia Alba ◽  
Antifungal Action
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