scholarly journals Evaluation of the Burden of Unsuspected Pulmonary Tuberculosis and Co-Morbidity with Non-Communicable Diseases in Sputum Producing Adult Inpatients

PLoS ONE ◽  
2012 ◽  
Vol 7 (7) ◽  
pp. e40774 ◽  
Author(s):  
Matthew Bates ◽  
Justin O’Grady ◽  
Peter Mwaba ◽  
Lophina Chilukutu ◽  
Judith Mzyece ◽  
...  
BMJ Open ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. e033320 ◽  
Author(s):  
Fantu Abebe Eyowas ◽  
Marguerite Schneider ◽  
Biksegn Asrat Yirdaw ◽  
Fentie Ambaw Getahun

IntroductionMultimorbidity is the coexistence of two or more chronic non-communicable diseases (NCDs) in a given individual. Multimorbidity is increasing in low- and middle-income countries (LMICs) and challenging health systems. Individuals with multimorbidity are facing the risk of premature mortality, lower quality of life and greater use of healthcare services. However, despite the huge challenge multimorbidity brings in LMICs, gaps remain in mapping and synthesising the available knowledge on the issue. The focus of this scoping review will be to synthesise the extent, range and nature of studies on the epidemiology and models of multimorbidity care in LMICs.MethodsPubMed (MEDLINE) will be the main database to be searched. For articles that are not indexed in the PubMed, Scopus, PsycINFO and Cochrane databases will be searched. Grey literature databases will also be explored. There will be no restrictions on study setting or year of publication. Articles will be searched using key terms, including comorbidity, co-morbidity, multimorbidity, multiple chronic conditions and model of care. Relevant articles will be screened by two independent reviewers and data will be charted accordingly. The result of this scoping review will be presented using the Preferred Reporting Items for Systematic Review and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) checklist and reporting guideline.Ethics and disseminationThis scoping review does not require ethical approval. Findings will be published in peer-reviewed journal and presented at scientific conferences.


2019 ◽  
Vol 4 ◽  
pp. 110
Author(s):  
Rodrigo M. Carrillo-Larco ◽  
J. Gonzalo Acevedo-Rodriguez ◽  
Carlos Altez-Fernandez ◽  
Karol Ortiz-Acha ◽  
Cesar Ugarte-Gil

Background: Cutaneous leishmaniasis is a prevalent communicable disease in low- and middle-income countries, where non-communicable diseases like skin cancer are on the rise. However, the study of multi-morbidity or co-morbidity between communicable and non-communicable diseases is limited, and even null for some tropical or neglected diseases. Nevertheless, looking at these conditions together instead of as isolated entities in places where these illnesses exist, could show new prevention and treatment paths. We aimed to summarize and critically appraise the epidemiological evidence on the association between cutaneous leishmaniasis and skin cancer. Methods: Following the PRISMA guidelines, we conducted a systematic review using five search engines (Embase, Medline, Global Health, Scopus and Web of Science). We sought observational studies in which the outcome was skin cancer whilst the exposure was cutaneous leishmaniasis; these conditions should have had laboratory or pathology confirmation. Results: No epidemiological investigations have studied the association between cutaneous leishmaniasis and skin cancer. Most of the evidence about the association of interest is still based on case reports and other clinical observations rather than strong epidemiological observational studies. Conclusions: Research is much needed to verify the repeatedly clinical observation that cutaneous leishmaniasis may be a risk factor for skin cancer. This evidence could inform and guide early diagnosis or prevention of skin cancer in survivors of cutaneous leishmaniasis or where cutaneous leishmaniasis is still highly prevalent. Registration: PROSPERO ID CRD42018111230; registered on 16/10/18.


2021 ◽  
Author(s):  
Md. Ashfikur Rahman ◽  
Henry Ratul Halder ◽  
Satyajit Kundu ◽  
Md. Hasan Al Banna

Abstract Background Chronic non-communicable diseases, owing to their increasing prevalence, are the greatest constraint to disease burden reduction in Bangladesh. As a result, we concentrated on determining the prevalence and risk factors for major chronic non-communicable diseases (NCDs) among adult Bangladeshis. Methods Data from Bangladesh Demographic and Health Survey (BDHS) 2017-18 were analyzed. If a participant had diabetes or hypertension, it was classified as NCD. Whereas comorbidity is defined as a subject having both diabetes and hypertension. Both the unadjusted and adjusted log-binomial regression models considering the survey weights were employed to identify the factors associated with NCDs and comorbidity. Results The overall prevalence (age-adjusted) of NCDs (40.43% (95% CI: 40.29-40.56) diabetes and hypertension was 11.55% (95% CI: 11.46-11.64) and 35.04% (95% CI: 34.91-35.17), respectively, while 6.16% (95% CI: 6.09-6.23) of participants had comorbidity. The adjusted regression model shows that being aged >34 years, and overweight or obese were significant risk factors of all NCDs, where being involved in work and from rich households were found as risk factors of diabetes and comorbidity. Smoker participants and females were more likely to have hypertension compared to their counterparts. Contrary, being underweight was a protective factor of having NCDs, similarly, engage in work was found as protective factors of diabetes and co-morbidity. Conclusion A growing prevalence of diabetes, hypertension, and comorbidity was discovered in this study. To reduce the burden of these NCDs, it is necessary to take the necessary steps.


2012 ◽  
Vol 06 (04) ◽  
pp. 249-251
Author(s):  
M. Braun ◽  
J. Ried

ZusammenfassungDie 65. World Health Assembly hat die Bekämpfung nicht-übertragbarer Krankheiten in den Mittelpunkt globaler Aufmerksamkeit und Aktivität gerückt. Da Übergewicht bzw. Adipositas wesentliche Risikofaktoren für einen erheblichen Teil dieser Erkrankungen darstellen, kommt damit der Prävention (aber auch der Therapie) erhöhten Körpergewichtes in der Programmatik der WHO besondere Bedeutung zu. Gleichzeitig führen die hochgesteckten Ziele der WHO in das fundamentale Dilemma, dass es keine Instrumente gibt, die angestrebten Prävalenz- und Reduktionsraten im vorgegebenen Zeitrahmen zu erreichen. Daraus ergeben sich eine Reihe ethischer und sozialer Fragen, unter anderem nach dem zu Grunde gelegten Modell der Adipositas und den impliziten und expliziten Verantwortlichkeiten für ihre Bekämpfung.


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