scholarly journals Sero-prevalence and trends of transfusion-transmissible infections among blood donors at Bahir Dar district blood bank, northwest Ethiopia: A four year retrospective study

PLoS ONE ◽  
2019 ◽  
Vol 14 (4) ◽  
pp. e0214755 ◽  
Author(s):  
Elias Shiferaw ◽  
Wasihun Tadilo ◽  
Iyasu Melkie ◽  
Mikru Shiferaw
PLoS ONE ◽  
2017 ◽  
Vol 12 (7) ◽  
pp. e0180416 ◽  
Author(s):  
Belete Biadgo ◽  
Elias Shiferaw ◽  
Berhanu Woldu ◽  
Kefyalew Addis Alene ◽  
Mulugeta Melku

Author(s):  
V. Siva Sankara Naik ◽  
Neeraja M. ◽  
Sujeeva Swapna R. ◽  
Bhavani C. ◽  
Sravani P. ◽  
...  

Background: Critical part of transfusion is effective screening of TTI, to reduce the risk of transmission is as safe as possible. The present study has undertaken to focus on seroprevalence of TTIs among both voluntary and replacement donors and also to project epidemiological data of TTIs in this community.Methods: This is a retrospective study conducted from January 2014 to December 2018. All blood samples collected from donors were screened for HIV, HBV, HCV, Syphilis and malaria according to blood bank policy. Before drawing blood, donors were asked to fill pre structured Blood bank questionnaire and consent form.Results: In this present 5-year study, total number of blood donor population was 54937, among them voluntary donors were 33891 and replacement donors were 21046. Out of 33891 voluntary donors, 33486(98.8%) were males and remaining 405(1.19%) were females. All replacement donors (21046) were males. The seroprevalence of HBV was highest, 1.82% (1003/54937) followed by HCV 0.31% (175/54937) in all the donors. The seropositivity for HIV is 0.23% (129/54937), for syphilis 0.04% (24/54937) and for malaria 0.01% (6/54937).Conclusions: National blood transfusion policy should be strengthening the standards and quality of screening across the country. For blood screening, resources and appropriate screening assays must be available at all health centres.


2021 ◽  
pp. 42-43
Author(s):  
Neha Patel ◽  
Sanjay Chaudhari ◽  
Sonal Chitroda

Background: India has the second highest HIV population in the world with about 2.5-3.0 million cases. Blood transfusion saves millions of lives worldwide each year but Blood transfusion is an important mode of transmission of infections to recipients and at the same time it is also associated with large number of complications including transfusion-transmissible infections (TTIs). Aims & objective: to study the prevalence of HIVin blood donors of A.D.Gorwala Blood bank From January 2005 To December 2010. Methods: A retrospective study was conducted among blood donors through the years 2005-2010. Sera from blood donors were tested for the detection of Anti HIV by using third generation ELISA tests, strictly following the instruction of manufacturers. The donor information was collected through the donor registers from A.D. Gorwala Blood Bank. Result: From the total of 28,371 screened blood samples collected, the prevalence of HIV in blood donors in the blood bank was 0.23% in the ve consecutive years but the trend of HIV infection has decreased from 2005(0.31%) to 2010 (0.04%). The age groups18-30 has the highest prevalence and the age group 51-60 was the lowest prevalence of HIV infection. The Prevalence of HIV among male (0.18%) was higher than in female donors (0.05%). The trend of HIVinfection was decreasing for both male and female blood donors. Conclusion: The analysis of HIV seroprevalence among blood donors through the year 2005- 2010 showed a signicantly decreasing trend, probably due to the cumulative effect of increasing awareness of HIVand improved screening system for safe blood donation.


Author(s):  
Shairoly Singh ◽  
Ishan Arora ◽  
Shireen Singh

Background: In India, a large majority of blood donors are deferred due to anemia. Anemia is a temporary cause of deferral which can be easily treated. Deferrals due to anemia can be easily identified in blood bank and can be treated and managed effectively.Methods: A retrospective study was carried out in Department of Blood Bank of Pt. Jawahar Lal Nehru Govt. Medical College, Chamba (H.P) over a time period of one year from 1st Jan 2017 to 31st Dec 2017.Results: We observed that the total number of deferrals was 90 out of all blood donors forming 9%. Out of all deferrals, those due to anemia were 23 (25.5%). Prevalence of anemia in female donors is much higher, constituting 26.31% and anemia in male donors in our study is lower forming 1.8%.Conclusions: Our study concluded that percentage of anemia is much higher in females than males. Educating and counseling females about prevention and treatment of anemia would help in lowering the percentage of anemia in females in our community.


2022 ◽  
Vol Volume 13 ◽  
pp. 11-19
Author(s):  
Berhanu Woldu ◽  
Mulugeta Melku ◽  
Elias Shiferaw ◽  
Belete Biadgo ◽  
Molla Abebe ◽  
...  

2021 ◽  
Vol 8 (14) ◽  
pp. 840-843
Author(s):  
Harjot Kaur ◽  
Parul Garg ◽  
Nirmaljot Kaur ◽  
Harmandeep Singh ◽  
Guneet Kaur Bakshi ◽  
...  

BACKGROUND Blood transfusion has been a boon to medical science, but at the same time, it exposes millions of people to transfusion transmitted infections (TTI). TTI are the infections that are transmissible from one person to another through parenteral administration of blood / blood products. Various TTIs are hepatitis C (HCV), hepatitis B (HBV), syphilis, human immunodeficiency viruses (HIV) and malaria. With increasing use of blood transfusion, chances of transmission of TTIs is very common but proper screening of donor blood has reduced the chances of TTI. The present study was done to know the seroprevalence of HCV, HBV, HIV and syphilis and their coinfections. METHODS A retrospective study was conducted by reviewing the records from January 2015 to December 2019 at a blood bank of Guru Ram Das Institute of Medical Sciences and Research at Amritsar, Punjab. Number of donors included in the study were 43,037. All the donors who came to blood bank were tested for TTIs by enhanced chemiluminescent immunoassay. METHODS A retrospective study was conducted by reviewing the records from January 2015 to December 2019 at a blood bank of Guru Ram Das Institute of Medical Sciences and Research at Amritsar, Punjab. Number of donors included in the study were 43,037. All the donors who came to blood bank were tested for TTIs by enhanced chemiluminescent immunoassay. RESULTS Number of donors tested for TTI was 43,037. Out of 43037, 1739 patients had serological evidence of TTIs, out of which 1669 (96.19 %) had mono-infection and 70 (4.04 %) had coinfections. HCV & HBV (28 / 70) was the most common combination, followed by HCV & HIV (20 / 70), HCV & syphilis (9 / 70), HIV & syphilis (5 / 70), HBV & syphilis (3 / 70) and HBV & HIV (1 / 70). Two donors had HIV, HCV & syphilis coinfections and two donors had HIV, HBV & HCV coinfections. CONCLUSIONS The present study documents the high prevalence of TTI out of which hepatitis C is the most common followed by hepatitis B. Among coinfections, two most prevalent coinfections are HCV & HBV and HCV & HIV and it is important to screen for these coinfections due to their impact on the course of disease as well as quality of life. This shows the increasing evidence of transfusion transmissible infection in blood donors in spite of advanced and vigilant screening of donated blood prior to transfusion. So, strategies should be devised for monitoring the implementation of post donation counselling for recruitment of safe donors. KEYWORDS Coinfections, Transfusion Transmitted Infections, Seroprevalence


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