Early-Onset Schizophrenia in a paediatric population of French psychiatric and medico-social care centres: A cross sectional study

Abstract Objective To measure the experience of the person having a rare disease in order to identify objectives for optimal care in the health care received by these patients. Methods. A cross-sectional study was conducted in Spain involving patients associated with the Spanish Rare Diseases Federation [Federación Española de Enfermedades Raras] (FEDER). A modified version of the PREM IEXPAC [Instrumento para evaluar la Experiencia del Paciente Crónico] instrument was used (IEXPAC-rare-diseases). Scores ranged between 0 (worst experience) and 10 (best experience). Results A total of 261 caregivers (in the case of paediatric population) and patients with rare diseases (response rate 54.4%) replied. 232 (88.9%) were adult patients and 29 (11.1%) caregivers of minor patients. Most males, 227 (87%), with an average age of 38 (SD 13.6) years. The mean time since confirmation of diagnosis was 7.8 (SD 8.0) years. The score in this PREM was 3.5 points out to 10 (95%CI 3.2–3.8, SD 2.0). Caregivers of paediatric patients scored higher, except for coordination of social and healthcare services. Conclusions There are wide and important areas for improvement in the care of patients with rare diseases. This study involves a first assesment of the experience of patients with rare diseases in Spain.

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Establishing normative foot posture index values for the paediatric population: a cross-sectional study

Journal of Foot and Ankle Research ◽

10.1186/s13047-016-0156-3 ◽

2016 ◽

Vol 9 (1) ◽

Cited By ~ 17

Author(s):

Gabriel Gijon-Nogueron ◽

Jesus Montes-Alguacil ◽

Pilar Alfageme-Garcia ◽

Jose Antonio Cervera-Marin ◽

Jose Miguel Morales-Asencio ◽

...

Keyword(s):

Paediatric Population ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Foot Posture Index ◽

Posture Index ◽

Foot Posture

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The characteristics of newly diagnosed adult early-onset diabetes: a population-based cross-sectional study

Scientific Reports ◽

10.1038/srep46534 ◽

2017 ◽

Vol 7 (1) ◽

Cited By ~ 12

Author(s):

Xiantong Zou ◽

Xianghai Zhou ◽

Linong Ji ◽

Wenying Yang ◽

Juming Lu ◽

...

Keyword(s):

Early Onset ◽

Population Based ◽

Cross Sectional Study ◽

Newly Diagnosed ◽

Sectional Study ◽

Cross Sectional ◽

Onset Diabetes

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Gender differences in the use of atypical antipsychotics in early-onset schizophrenia: a nationwide population-based study in Brazil

BMC Psychiatry ◽

10.1186/s12888-021-03327-7 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Izabela Fulone ◽

Marcus Tolentino Silva ◽

Luciane Cruz Lopes

Keyword(s):

Gender Differences ◽

Early Onset ◽

Atypical Antipsychotics ◽

Population Based ◽

Cross Sectional Study ◽

Administrative Database ◽

Age Group ◽

Early Onset Schizophrenia ◽

Cross Sectional ◽

Assistance Programme

Abstract Background The use of atypical antipsychotics for the treatment of schizophrenia and other mental disorders in populations under 18 years of age is increasing worldwide. Little is known about treatment patterns and the influence of gender differences, which may be a predictor of clinical outcomes. The aim of this study was to investigate gender differences in the use of atypical antipsychotics in patients with early-onset schizophrenia (EOS) assisted by the public health system in Brazil. Methods We conducted a cross-sectional study of outpatients with EOS aged 10 to 17 years who received at least one provision of atypical antipsychotics (clozapine, olanzapine, risperidone, quetiapine or ziprasidone) from a large Brazilian pharmaceutical assistance programme. Data were retrieved from a nationwide administrative database from 2008 to 2017. Results Of the 49,943 patients with EOS, 63.5% were males, and the mean age was 13.6 years old. The patients were using risperidone (62.5%), olanzapine (19.6%), quetiapine (12.4%), ziprasidone (3.3%) and clozapine (2.2%). We found gender differences, especially in the 13–17 year age group (65.1% for males vs. 34.9% for females, p < 0.001), in the use of risperidone (72.1% for males vs. 27.9% for females, p < 0.001) and olanzapine (66.5% for males vs. 33.5% for females, p < 0.001). Only in the 13 to 17 years age group were the prescribed doses of olanzapine (p = 0.012) and quetiapine (p = 0.041) slightly higher for males than for females. Conclusions Our findings showed gender differences among patients diagnosed with EOS and who received atypical antipsychotics. More attention should be devoted to gender differences in research and clinical practice.

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The Rising Double Heterozygous Cases of Haemoglobinopathies In Paediatric Population-A Hospital Based Cross Sectional Study

IOSR Journal of Dental and Medical Sciences ◽

10.9790/0853-1510043336 ◽

2016 ◽

Vol 15 (10) ◽

pp. 33-36

Author(s):

Vikas Dagar ◽

Rajesh Kate ◽

Ashwinkumar Barsagade ◽

Pradeep Male

Keyword(s):

Paediatric Population ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional

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Primary care use of laboratory tests in Northern Ireland’s Western Health and Social Care Trust: a cross-sectional study

BMJ Open ◽

10.1136/bmjopen-2018-026647 ◽

2019 ◽

Vol 9 (6) ◽

pp. e026647

Author(s):

Magda Bucholc ◽

Maurice O’Kane ◽

Ciaran Mullan ◽

Siobhan Ashe ◽

Liam Maguire

Keyword(s):

Northern Ireland ◽

Laboratory Test ◽

Laboratory Tests ◽

Social Care ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Socioeconomic Characteristics ◽

Health And Social Care ◽

Test Ordering

ObjectivesTo describe the laboratory test ordering patterns by general practitioners (GPs) in Northern Ireland Western Health and Social Care Trust (WHSCT) and explore demographic and socioeconomic associations with test requesting.DesignCross-sectional study.SettingWHSCT, Northern Ireland.Participants55 WHSCT primary care medical practices that remained open throughout the study period 1 April 2011–31 March 2016.OutcomesTo identify the temporal patterns of laboratory test ordering behaviour for eight commonly requested clinical biochemistry tests/test groups in WHSCT. To analyse the extent of variations in laboratory test requests by GPs and to explore whether these variations can be accounted for by clinical outcomes or geographical, demographic and socioeconomic characteristics.ResultsThe median number of adjusted test request rates over 5 consecutive years of the study period decreased by 45.7% for urine albumin/creatinine ratio (p<0.000001) and 19.4% for lipid profiles (p<0.000001) while a 60.6%, 36.6% and 29.5% increase was observed for HbA1c(p<0.000001), immunoglobulins (p=0.000007) and prostate-speciﬁc antigen (PSA) (p=0.0003), respectively. The between-practice variation in test ordering rates increased by 272% for immunoglobulins (p=0.008) and 500% for HbA1c(p=0.0001). No statistically significant relationship between ordering activity and either demographic (age and gender) and socioeconomic factors (deprivation) or Quality and Outcome Framework scores was observed. We found the rural–urban differences in between-practice variability in ordering rates for lipid profiles, thyroid profiles, PSA and immunoglobulins to be statistically significant at the Bonferroni-adjusted significance level p<0.01.ConclusionsWe explored potential factors of the interpractice variability in the use of laboratory tests and found that differences in requesting activity appear unrelated to either demographic and socioeconomic characteristics of GP practices or clinical outcome indicators.

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