scholarly journals Differences between 3D isovoxel fat suppression VIBE MRI and CT models of proximal femur osseous anatomy: A preliminary study for bone tumor resection planning

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0250334
Author(s):  
Choong Guen Chee ◽  
Hye Won Chung ◽  
Wanlim Kim ◽  
Min A. Yoon ◽  
So Myoung Shin ◽  
...  
Keyword(s):  
Proximal Femur ◽  
Femoral Shaft ◽  
Fat Suppression ◽  
Concordance Correlation Coefficient ◽  
Maximum Difference ◽  
Reference Standard ◽  
3D Mri ◽  
Concordance Correlation ◽  
The Mean ◽  
Mean Differences

Purpose To evaluate the osseous anatomy of the proximal femur extracted from a 3D-MRI volumetric interpolated breath-hold (VIBE) sequence using either a Dixon or water excitation (WE) fat suppression method, and to measure the overall difference using CT as a reference standard. Material and methods This retrospective study reviewed imaging of adult patients with hip pain who underwent 3D hip MRI and CT. A semi-automatically segmented CT model served as the reference standard, and MRI segmentation was performed manually for each unilateral hip joint. The differences between Dixon-VIBE-3D-MRI vs. CT, and WE-VIBE-3D-MRI vs. CT, were measured. Equivalence tests between Dixon-VIBE and WE-VIBE models were performed with a threshold of 0.1 mm. Bland–Altman plots and Lin’s concordance-correlation coefficient were used to analyze the agreement between WE and Dixon sequences. Subgroup analyses were performed for the femoral head/neck, intertrochanteric, and femoral shaft areas. Results The mean and maximum differences between Dixon-VIBE-3D-MRI vs. CT were 0.2917 and 3.4908 mm, respectively, whereas for WE-VIBE-3D-MRI vs. CT they were 0.3162 and 3.1599 mm. The mean differences of the WE and Dixon methods were equivalent (P = 0.0292). However, the maximum difference was not equivalent between the two methods and it was higher in WE method. Lin’s concordance-correlation coefficient showed poor agreement between Dixon and WE methods. The mean differences between the CT and 3D-MRI models were significantly higher in the femoral shaft area (P = 0.0004 for WE and P = 0.0015 for Dixon) than in the other areas. The maximum difference was greatest in the intertrochanteric area for both techniques. Conclusion The difference between 3D-MR and CT models were acceptable with a maximal difference below 3.5mm. WE and Dixon fat suppression methods were equivalent. The mean difference was highest at the femoral shaft area, which was off-center from the magnetization field.

scholarly journals Measurement of acetabular wall indices: comparison between CT and plain radiography

2021 ◽  
Author(s):  
Jaron Nazaroff ◽  
Bryan Mark ◽  
James Learned ◽  
Dean Wang
Keyword(s):  
Clinical Decision Making ◽  
Posterior Wall ◽  
Clinical Decision ◽  
Anterior Wall ◽  
Concordance Correlation ◽  
Ct Measurements ◽  
Axial Ct ◽  
The Mean ◽  
Mean Differences ◽  
Acetabular Wall

Abstract The purpose of this study was to compare measurements of anterior wall index (AWI) and posterior wall index (PWI) on computed tomography (CT) to those on radiographs (XR). A consecutive cohort of 33 patients (45 hips total) being evaluated for hip pain with both XR and CT was examined. Preoperative measurements of AWI and PWI were performed utilizing supine anteroposterior pelvic XR and coronal and swiss axial CT scans by two independent raters. Mean differences between XR and CT measurements were compared, and agreement between measurements was assessed using the concordance correlation coefficient (rc) and Bland–Altman analysis. A total of 39 hips in 28 patients were analyzed. The mean patient age was 31.1 ± 9.0 years, and 50% were female. Mean AWI and PWI on XR was 0.50 ± 0.14 and 0.91 ± 0.12, respectively. Measured values of AWI were consistently larger (0.08 ± 0.10, P < 0.01) on XR compared with both coronal and swiss axial CT, with moderate agreement between XR and CT measurements (rc = 0.68–0.70). Measured values of PWI were consistently smaller (0.15 ± 0.12, P < 0.05) on XR compared with both coronal and swiss axial CT, with poor agreement between XR and CT measurements (rc = 0.37–0.45). Measured values of acetabular wall indices on XR were consistently larger for AWI and smaller for PWI relative to CT. Agreement between XR and CT measures of the indices were moderate to poor. This highlights the need for standardization of XR- and CT-based measurements to improve assessment of acetabular coverage and subsequent clinical decision-making.

Comparison of Early Measurements of the Distraction Index, Norberg Angle on Distracted View and the Official Radiographic Evaluation of the Hips of 215 Dogs from Two Guide Dog Training Schools

2018 ◽  
Vol 31 (06) ◽  
pp. 445-451 ◽  
Author(s):  
Mathieu Taroni ◽  
Eric Viguier ◽  
Paul Pillard ◽  
Véronique Livet ◽  
Thibaut Cachon ◽  
...  
Keyword(s):  
Correlation Coefficient ◽  
Characteristic Curve ◽  
Radiographic Evaluation ◽  
Concordance Correlation Coefficient ◽  
Concordance Correlation ◽  
Dog Training ◽  
Training Schools ◽  
The Mean ◽  
Extended View ◽  
Norberg Angle

Objectives The main purpose of this article is to evaluate the correlation between the distraction index (DI) and Norberg angle values in distracted hips (distraction Norberg angle, DNA) at 4 months of age and the official hip score based on the Fédération Cynologique Internationale (FCI) grid at 12 months of age. Methods For dogs (n = 215) from two guide dog training organizations, the DI and DNA were measured by a single expert on distraction radiographs performed at 4 months of age. The FCI score was determined by the same expert at 12 months of age on a standard hip-extended view.Statistical analysis included receiver operating characteristic curve analysis and concordance correlation coefficient calculation. Results The mean DI was 0.48, the mean DNA was 86.5° and 59.5% of hips had an A FCI score. The concordance correlation coefficient of DI and DNA was 0.78. The DI threshold for D- and E-scored hips that was associated with the least misclassification was 0.58 (sensitivity [Se] = 0.6, specificity [Sp] = 0.82). The DNA threshold that was associated with the least misclassification was 85° (Se = 0.83, Sp = 0.68). Clinical Significance DNA has a fair correlation with DI at 4 months and reflects hip passive laxity. D and E FCI scores at 12 months cannot be reliably predicted from the 4 months value of DI or DNA but 96% of hips with DI < 0.58 at 4 months had an A, B or C FCI score at 12 months of age. Similarly, 98% of hips with DNA > 85° at 4 months had an A, B or C FCI score at 12 months of age.

665 Reliability of Resting Energy Expenditure in Major Burns: Comparison Between Measured and Predictive Equations

2020 ◽  
Vol 41 (Supplement_1) ◽  
pp. S177-S178
Author(s):  
Jun Hur ◽  
Dohern Kym
Keyword(s):  
Energy Expenditure ◽  
Resting Energy Expenditure ◽  
Concordance Correlation Coefficient ◽  
Altman Analysis ◽  
Concordance Correlation ◽  
Predictive Equations ◽  
Severe Burns ◽  
The Mean ◽  
Poor Outcomes ◽  
Resting Energy

Abstract Introduction Poor outcomes can result from inadequate energy intake. We aimed to investigate the reliability of resting energy expenditure (REE) measured by indirect calorimetry (IC) with REE calculated using predictive equations for nutritional support in patients with major burns. Methods REE was measured using IC and compared with predictive equations in 215 adult severe burns patients from Jan 2011 to Jun 2015. Agreement between IC and predictive equations was assessed using Bland-Altman methods. Results All predictive equations were compared with REE measured using IC. The mean measured REE was 1712 kcal/d. Bland-Altman analysis showed that 1.2 times HBE, Thumb 25, and Ireton-Jones equations had higher accuracy and reliability. The concordance correlation coefficient was higher (0.49) in the Ireton-Jones equation, and root mean square error (RMSE) was lowest (471.5) in the Thumb 25 equation. The proportion of patients with predicted REE within ±10% of measured REE was highest with Thumb 25 (52.5%). Other equations for burns patients had higher mean bias and overestimated REE when compared with IC results. Conclusions This study suggests that Thumb 25 can be used as an alternative method for estimating energy requirements of patients with major burns when IC is not available or applicable. Applicability of Research to Practice Harrison-Benedict known as standard equation failed to show superiority to others in burns. Burn-specific equations are tend to overestimate ebergy requirements.

A Multimethod Approach to Evaluate Chemical Dot Thermometers for Oral Temperature Measurement

2006 ◽  
Vol 14 (3) ◽  
pp. 151-162 ◽  
Author(s):  
Wendy M. Fallis ◽  
Kathy Hamelin ◽  
Xikui Wang ◽  
Jackie Symonds
Keyword(s):  
Temperature Measurement ◽  
Concordance Correlation Coefficient ◽  
Operative Delivery ◽  
Oral Temperature ◽  
Concordance Correlation ◽  
Altman Plot ◽  
Single Use ◽  
Electronic Thermometer ◽  
Multimethod Approach ◽  
The Mean

Limited research has explored the accuracy of chemical dot thermometers for oral temperature measurement in adults. This study was undertaken to assess the agreement between oral temperatures taken with an electronic thermometer and single-use chemical dot thermometers in healthy women undergoing surgical delivery. During operative delivery, oral temperatures taken every 15 minutes with both the reference electronic thermometer (ETT) and a Tempa. DOT (TDT) chemical dot thermometer were compared. Data were analyzed using paired t tests, the Bland and Altman plot, and the concordance correlation coefficient. The total number of paired observations for the 62 subjects was 212. The mean difference between the two measurements was 0.35 ± 0.32 °C (p < .0001, 95% CI 0.31, 0.40). Additional analysis indicated a serious undermeasurement by TDT of ETT temperatures. Data from multiple methods of analysis indicate that the Tempa. DOT chemical dot thermometer significantly undermeasures ETT and is not a reliable indicator of oral temperature.

scholarly journals Early mortality in hip fracture patients admitted during first wave of the COVID-19 pandemic in Northern Italy: a multicentre study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Dante Dallari ◽  
Luigi Zagra ◽  
Pietro Cimatti ◽  
Nicola Guindani ◽  
Rocco D’Apolito ◽  
...  
Keyword(s):  
Hip Fracture ◽  
Mortality Rate ◽  
Multicentre Study ◽  
Proximal Femur ◽  
Femur Fracture ◽  
Northern Italy ◽  
Proximal Femur Fracture ◽  
Time To Surgery ◽  
Fracture Management ◽  
The Mean

Abstract Background Treatment of hip fractures during the coronavirus disease 2019 (COVID-19) pandemic has posed unique challenges for the management of COVID-19-infected patients and the maintenance of standards of care. The primary endpoint of this study is to compare the mortality rate at 1 month after surgery in symptomatic COVID-positive patients with that of asymptomatic patients. A secondary endpoint of the study is to evaluate, in the two groups of patients, mortality at 1 month on the basis of type of fracture and type of surgical treatment. Materials and methods For this retrospective multicentre study, we reviewed the medical records of patients hospitalised for proximal femur fracture at 14 hospitals in Northern Italy. Two groups were formed: COVID-19-positive patients (C+ group) presented symptoms, had a positive swab for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and received treatment for COVID-19; COVID-19-negative patients (C− group) were asymptomatic and tested negative for SARS-CoV-2. The two groups were compared for differences in time to surgery, survival rate and complications rate. The follow-up period was 1 month. Results Of the 1390 patients admitted for acute care for any reason, 477 had a proximal femur fracture; 53 were C+ but only 12/53 were diagnosed as such at admission. The mean age was > 80 years, and the mean American Society of Anesthesiologists (ASA) score was 3 in both groups. There was no substantial difference in time to surgery (on average, 2.3 days for the C+ group and 2.8 for the C− group). As expected, a higher mortality rate was recorded for the C+ group but not associated with the type of hip fracture or treatment. No correlation was found between early treatment (< 48 h to surgery) and better outcome in the C+ group. Conclusions Hip fracture in COVID-19-positive patients accounted for 11% of the total. On average, the time to surgery was > 48 h, which reflects the difficulty of maintaining normal workflow during a medical emergency such as the present pandemic and notwithstanding the suspension of non-urgent procedures. Hip fracture was associated with a higher 30-day mortality rate in COVID-19-positive patients than in COVID-19-negative patients. This fact should be considered when communicating with patients and/or their family. Our data suggest no substantial difference in hip fracture management between patients with or without COVID-19 infection. In this sample, the COVID-19-positive patients were generally asymptomatic at admission; therefore, routine screening is recommended. Level of evidence Therapeutic study, level 4.

scholarly journals Effectiveness of Home-Based Occupational Therapy on COPM Performance and Satisfaction Scores in Patients with COPD

2020 ◽  
pp. 000841742097112
Author(s):  
Eleonore H. Koolen ◽  
Martijn A. Spruit ◽  
Marianne de Man ◽  
Jeanine C. Antons ◽  
Elieke Nijhuis ◽  
...  
Keyword(s):  
Occupational Therapy ◽  
Integrated Management ◽  
Performance Measure ◽  
Occupational Performance ◽  
Post Intervention ◽  
Canadian Occupational Performance Measure ◽  
Home Based ◽  
Copd Patients ◽  
The Mean ◽  
Mean Differences

Background. Occupational therapy (OT) may be an important intervention in patients with COPD, but studies show conflicting results. Purpose. To evaluate the effectiveness of home-based monodisciplinary OT in COPD patients Method. We conducted an observational clinical study. Main outcomes were the mean differences in the Canadian Occupational Performance Measure (COPM) performance and satisfaction scores, pre and post intervention. Findings. Pre- and postintervention data were obtained from 41 patients. Statistically significant increases were observed in COPM performance (5.0 ± 1.1 versus 6.9 ± 0.9; P<0.001) and satisfaction (4.6 ± 1.3 versus 6.9 ± 1.0; P<0.001). The most frequently reported occupational performance problems were found in the domains of productivity (47%) and mobility (40%), fewer in self-care (10%) and the least in leisure (3%). Implications. Home-based monodisciplinary OT can contribute significantly to the improvement of daily functioning of patients with COPD. OT should therefore be considered more often as part of the integrated management of these patients.

scholarly journals Transcranial Evoked Potentials Can Be Reliably Recorded with Active Electrodes

2021 ◽  
Vol 11 (2) ◽  
pp. 145
Author(s):  
Marco Mancuso ◽  
Valerio Sveva ◽  
Alessandro Cruciani ◽  
Katlyn Brown ◽  
Jaime Ibáñez ◽  
...  
Keyword(s):  
Healthy Subjects ◽  
Magnetic Stimulation ◽  
Primary Motor Cortex ◽  
The Other ◽  
Concordance Correlation Coefficient ◽  
Concordance Correlation ◽  
Eeg Signals ◽  
Active Electrode ◽  
Viable Solution ◽  
Space Projection

Electroencephalographic (EEG) signals evoked by transcranial magnetic stimulation (TMS) are usually recorded with passive electrodes (PE). Active electrode (AE) systems have recently become widely available; compared to PE, they allow for easier electrode preparation and a higher-quality signal, due to the preamplification at the electrode stage, which reduces electrical line noise. The performance between the AE and PE can differ, especially with fast EEG voltage changes, which can easily occur with TMS-EEG; however, a systematic comparison in the TMS-EEG setting has not been made. Therefore, we recorded TMS-evoked EEG potentials (TEPs) in a group of healthy subjects in two sessions, one using PE and the other using AE. We stimulated the left primary motor cortex and right medial prefrontal cortex and used two different approaches to remove early TMS artefacts, Independent Component Analysis and Signal Space Projection—Source Informed Recovery. We assessed statistical differences in amplitude and topography of TEPs, and their similarity, by means of the concordance correlation coefficient (CCC). We also tested the capability of each system to approximate the final TEP waveform with a reduced number of trials. The results showed that TEPs recorded with AE and PE do not differ in amplitude and topography, and only few electrodes showed a lower-than-expected CCC between the two methods of amplification. We conclude that AE are a viable solution for TMS-EEG recording.

A repeated measures concordance correlation coefficient

2007 ◽  
Vol 26 (16) ◽  
pp. 3095-3113 ◽  
Author(s):  
Tonya S. King ◽  
Vernon M. Chinchilli ◽  
Josep L. Carrasco
Keyword(s):  
Correlation Coefficient ◽  
Repeated Measures ◽  
Concordance Correlation Coefficient ◽  
Concordance Correlation

scholarly journals Estimation of coronary wave intensity analysis using noninvasive techniques and its application to exercise physiology

2016 ◽  
Vol 310 (5) ◽  
pp. H619-H627 ◽  
Author(s):  
Christopher J. Broyd ◽  
Sukhjinder Nijjer ◽  
Sayan Sen ◽  
Ricardo Petraco ◽  
Siana Jones ◽  
...  
Keyword(s):  
Coronary Circulation ◽  
Exercise Physiology ◽  
Left Ventricular ◽  
Wave Intensity ◽  
Concordance Correlation Coefficient ◽  
Intensity Analysis ◽  
Wave Intensity Analysis ◽  
Concordance Correlation ◽  
Decompression Wave ◽  
Pulsed Wave Doppler

Wave intensity analysis (WIA) has found particular applicability in the coronary circulation where it can quantify traveling waves that accelerate and decelerate blood flow. The most important wave for the regulation of flow is the backward-traveling decompression wave (BDW). Coronary WIA has hitherto always been calculated from invasive measures of pressure and flow. However, recently it has become feasible to obtain estimates of these waveforms noninvasively. In this study we set out to assess the agreement between invasive and noninvasive coronary WIA at rest and measure the effect of exercise. Twenty-two patients (mean age 60) with unobstructed coronaries underwent invasive WIA in the left anterior descending artery (LAD). Immediately afterwards, noninvasive LAD flow and pressure were recorded and WIA calculated from pulsed-wave Doppler coronary flow velocity and central blood pressure waveforms measured using a cuff-based technique. Nine of these patients underwent noninvasive coronary WIA assessment during exercise. A pattern of six waves were observed in both modalities. The BDW was similar between invasive and noninvasive measures [peak: 14.9 ± 7.8 vs. −13.8 ± 7.1 × 104 W·m−2·s−2, concordance correlation coefficient (CCC): 0.73, P < 0.01; cumulative: −64.4 ± 32.8 vs. −59.4 ± 34.2 × 102 W·m−2·s−1, CCC: 0.66, P < 0.01], but smaller waves were underestimated noninvasively. Increased left ventricular mass correlated with a decreased noninvasive BDW fraction ( r = −0.48, P = 0.02). Exercise increased the BDW: at maximum exercise peak BDW was −47.0 ± 29.5 × 104 W·m−2·s−2 ( P < 0.01 vs. rest) and cumulative BDW −19.2 ± 12.6 × 103 W·m−2·s−1 ( P < 0.01 vs. rest). The BDW can be measured noninvasively with acceptable reliably potentially simplifying assessments and increasing the applicability of coronary WIA.

The Holland nail®: a universal implant for fractures of the proximal femur and the femoral shaft

Injury ◽  
2004 ◽  
Vol 35 (2) ◽  
pp. 170-178 ◽  
Author(s):  
P Krastman ◽  
W.N Welvaart ◽  
S.J.M Breugem ◽  
A.B van Vugt
Keyword(s):  
Proximal Femur ◽  
Femoral Shaft
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