scholarly journals Clinical efficacy of Curcuvet and Boswellic acid combined with conventional nutraceutical product: An aid to canine osteoarthritis

PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0252279
Author(s):  
Chiara Caterino ◽  
Federica Aragosa ◽  
Giovanni Della Valle ◽  
Dario Costanza ◽  
Francesco Lamagna ◽  
...  

Introduction Osteoarthritis is a progressive degenerative joint disease which is high prevalent in dogs. In the late stage of the disease, it determines chronic neuropathic pain which leads to reduced quality-of-life in affected patients. To date it has not yet been identified a specific treatment, but it has been proved that nutraceutical and dietary supplements may play an important role in controlling inflammation and pain. The aim of this study was to evaluate, by the use of force plate gait analysis, the clinical efficacy of Boswellia and Curcuvet® combined with conventional nutraceutical therapy compared with conventional nutraceutical alone in dogs affected by osteoarthritis. Materials and methods Twenty client-owned dogs, over 12 months old and 20 kg of body-weight, with a confirmed diagnosis of Osteoarthritis, were included in this randomized, double-blinded study. The dogs were randomly divided into two groups: the first group (A) received a conventional nutraceutical (consisted in a preparation of glucosamine, chondroitin sulfate, fish-oil containing 80% of omega 3-fatty acid, vitamin C and E, saccharomyces Cerevisiae) with a combination of acid boswellic and Curcuvet®, while the second group (B) received a conventional nutraceutical. All the enrolled dogs underwent a washout period before starting the treatment with nutraceuticals products which were the only admitted treatment over the study period. A full orthopaedic and neurologic examination, and force plate gait analysis were performed before starting the treatment, at 45, 90, and 60 days post-treatment. Ground reaction forces were recorded and analyzed. Results Twenty dogs were enrolled in the study. In both groups there was an increasing values of ground reaction forces. These results might indicate that both nutraceutical products determined a better condition in terms of pain feeling but that effect is much more visible after 60 days from the end of the administration in treated group. Discussion In conclusion Curcuvet in combination with Boswellic acid could be considered a valid aid in a multimodal treatment for canine osteoarthritis.

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0256011
Author(s):  
Giovanni Della Valle ◽  
Chiara Caterino ◽  
Federica Aragosa ◽  
Fabiana Micieli ◽  
Dario Costanza ◽  
...  

Introduction Cranial cruciate ligament failure is one of the principal causes of canine lameness. Several surgical procedures were proposed to achieve joint stabilisation; among these, the Modified Maquet Procedure involves using a titanium foam wedge to achieve and maintain the tibial tuberosity advancement. The force-plate analysis provides to objectively assess normal and abnormal gait and the outcome of different surgical techniques. The study evaluates the outcome of limbs that underwent Modified Maquet Procedure using land-force plate analysis comparing the operated limb with its healthy contralateral one as a control. Materials and methods Thirty-five dogs with unilateral cranial cruciate ligament rupture were evaluated. Outcome after surgery was assessed by orthopaedic and radiographic evaluations and force plate gait analysis performed before surgery, at 15, 30 and 90 days after surgery. For objective comparison of ground reaction forces, data of operated limb were compared to contralateral limb on each time control and Symmetry Index at 90 days was determined. Healing radiographic signs, minor and major complication were reported. Results A significant improvement in ground reaction forces was reached in all the treated limbs between set time intervals. The median percentage increase in ground reaction forces was constant from 15 to 90 days, with a Symmetry Index >9 in 54.2% of patients suggesting a normal gait symmetry. A complete bone healing was noticed at 90 days follow-up radiographic assessment. We experienced three major (8.5%) and one minor (2.8%) complications. Conclusions To the Authors’ knowledge, this is the first study in the veterinary literature that assessed outcomes of dogs undergoing Modified Maquet Procedure for the treatment of cranial cruciate ligament rupture using force plate gait analysis and healthy contralateral limb as a control group. Our results confirm that Modified Maquet Procedure is an effective method to stabilise the stifle joint.


PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0243819
Author(s):  
Michelle Brønniche Møller Nielsen ◽  
Tenna Pedersen ◽  
Amalie Mouritzen ◽  
Anne Desiré Vitger ◽  
Lise Nikolic Nielsen ◽  
...  

In veterinary practice, a thorough gait examination is essential in the clinical workup of any orthopedic patient, including the large population of dogs with chronic pain as a result of osteoarthritis. The traditional visual gait examination is, however, a subjective discipline, and systems for kinetic gait analysis may potentially offer an objective alternative for gait assessment by the measurement of ground reaction forces. In order to avoid unnecessary testing of patients, a thorough, stepwise evaluation of the diagnostic performance of each system is recommended before clinical use for diagnostic purposes. The aim of the study was to evaluate the Tekscan pressure-sensitive walkway system by assessing precision (agreement between repetitive measurements in individual dogs) and overlap performance (the ability to distinguish dogs with lameness due to osteoarthritis from clinically healthy dogs). Direction of travel over the walkway was investigated as a possible bias. Symmetry indices are commonly used to assess lameness by comparing ground reaction forces across different combinations of limbs in each dog. However, SIs can be calculated in several different ways and specific recommendations for optimal use of individual indices are currently lacking. Therefore the present study also compared indices in order to recommend a specific index preferable for future studies of canine osteoarthritis. Forty-one clinically healthy dogs and 21 dogs with osteoarthritis were included in the study. High precision was demonstrated. The direction of travel over the walkway was excluded as a possible bias. A significant overlap was observed when comparing ground reaction forces measured in dogs with osteoarthritis compared to clinically healthy dogs. In some affected dogs, symmetry indices comparing contralateral limbs differed from clinically healthy dogs, but in general, the overlap performance was insufficient and, consequently, general use of this method for diagnostic purposes in dogs with osteoarthritis cannot be recommended.


2006 ◽  
Vol 3 (4) ◽  
pp. 209-216 ◽  
Author(s):  
Pia Gustås ◽  
Christopher Johnston ◽  
Stig Drevemo

AbstractThe objective of the present study was to compare the hoof deceleration and ground reaction forces following impact on two different surfaces. Seven unshod Standardbreds were trotted by hand at 3.0–5.7 m s− 1 over a force plate covered by either of the two surfaces, sandpaper or a 1 cm layer of sand. Impact deceleration data were recorded from one triaxial accelerometer mounted on the fore- and hind hooves, respectively. Ground reaction force data were obtained synchronously from a force plate, sampled at 4.8 kHz. The differences between the two surfaces were studied by analysing representative deceleration and force variables for individual horses. The maximum horizontal peak deceleration and the loading rates of the vertical and the horizontal forces were significantly higher on sandpaper compared with the sand surface (P < 0.001). In addition, the initial vertical deceleration was significantly higher on sandpaper in the forelimb (P < 0.001). In conclusion, it was shown that the different qualities of the ground surface result in differences in the hoof-braking pattern, which may be of great importance for the strength of the distal horse limb also at slow speeds.


2007 ◽  
Vol 23 (3) ◽  
pp. 180-189 ◽  
Author(s):  
Niell G. Elvin ◽  
Alex A. Elvin ◽  
Steven P. Arnoczky

Modern electronics allow for the unobtrusive measurement of accelerations outside the laboratory using wireless sensor nodes. The ability to accurately measure joint accelerations under unrestricted conditions, and to correlate them with jump height and landing force, could provide important data to better understand joint mechanics subject to real-life conditions. This study investigates the correlation between peak vertical ground reaction forces, as measured by a force plate, and tibial axial accelerations during free vertical jumping. The jump heights calculated from force-plate data and accelerometer measurements are also compared. For six male subjects participating in this study, the average coefficient of determination between peak ground reaction force and peak tibial axial acceleration is found to be 0.81. The coefficient of determination between jump height calculated using force plate and accelerometer data is 0.88. Data show that the landing forces could be as high as 8 body weights of the jumper. The measured peak tibial accelerations ranged up to 42 g. Jump heights calculated from force plate and accelerometer sensors data differed by less than 2.5 cm. It is found that both impact accelerations and landing forces are only weakly correlated with jump height (the average coefficient of determination is 0.12). This study shows that unobtrusive accelerometers can be used to determine the ground reaction forces experienced in a jump landing. Whereas the device also permitted an accurate determination of jump height, there was no correlation between peak ground reaction force and jump height.


2020 ◽  
Vol 30 (89) ◽  
pp. 13-20
Author(s):  
Dimitrije Cabarkapa ◽  
Andrew Fry ◽  
Damjana Cabarkapa ◽  
Arden Rogers ◽  
Eric Mosier

Aim: The purpose of this study was to quantify ground reaction forces for some of the most commonly utilised volleyball blocking approaches and to examine their kinetic and kinematic characteristics. Basic procedures: The study was comprised of 18 healthy recreationally active women who volunteered to participate. Immediately after completion of the warm-up protocol, subjects performed 5 blocking approaches: stationary blocking approach (SBA), shuffle block to the right (SHBR), shuffle block to the left (SHBL), swing block to the right (SWBR) and swing block to the left (SWBL). In order to allow adequate recovery, each trial was randomly assigned and separated by a 1-2 minute rest interval. A uni-axial force plate with data acquisition system sampling at 1000 Hz was used to measure ground reaction forces. Main findings: SWBR and SWBL unveiled the greatest peak concentric force and rate of force development when compared to SBA, while no difference was observed when compared to SHBR and SHBL. Results: No significant differences were observed in peak landing force, impulse, and vertical jump height between any of the blocking approaches examined in this study. Conclusions: Knowing biomechanical characteristics of some of the most commonly utilised volleyball blocking approaches may help athletes to appropriately respond and quickly adjust to the opponent’s attacking position. Kinetic and kinematic variables are likely to be augmented with an advanced level of competition and can be trained and improved by properly designed and implemented strength and conditioning programmes.


2008 ◽  
Vol 21 (03) ◽  
pp. 243-249 ◽  
Author(s):  
D. Damur ◽  
T. Guerrero ◽  
M. Haessig ◽  
P. Montavon ◽  
K. Voss

Summary Objective: To assess functional outcome in dogs with cranial cruciate ligament (CrCL) disease after tibial tuberosity advancement (TTA) using force plate gait analysis, and to evaluate parameters potentially influencing outcome. Study design: Prospective clinical study. Animals: Consecutive clinical patients (n=37) with CrCL-deficient stifles (n=40). Methods: The stifle joints were examined arthroscopically prior to TTA. Meniscal release was not performed if the medial meniscus was intact. Open medial arthrotomy and partial meniscectomy were performed in the presence of meniscal tears. Vertical ground reaction forces were measured preoperatively and at follow-up examinations four to 16 months postoperatively (mean: 5.9 months). The ground reaction forces of a group of 65 healthy dogs were used for the comparison. The potential effects of clinical parameters on functional outcome were evaluated statistically. Results: Complete CrCL rupture was identified in 28 joints, and partial CrCL rupture in 12 joints. The medial meniscus was damaged in 21 stifles. Vertical ground reaction forces were significantly higher at follow-up (P<0.01), but remained significantly lower than those of control dogs (P<0.01). Complications were identified in 25% of joints, and the dogs with complications had significantly lower peak vertical forces at follow-up than the dogs without complications (P=0.04). Other clinical parameters did not influence outcome. Conclusions: Tibial tuberosity advancement significantly improved limb function in dogs with CrCL disease, but did not result in complete return to function. Complications adversely affected functional outcome. Clinical significance: A return to a function of approximately 90% of normal can be expected in dogs with CrCL disease undergoing TTA.


2007 ◽  
Vol 23 (4) ◽  
pp. 322-329 ◽  
Author(s):  
Chip Wade ◽  
Mark S. Redfern

Locomotion over ballast surfaces provides a unique situation for investigating the biomechanics of gait. Although much research has focused on level and sloped walking on a smooth, firm surface in order to understand the common kinematic and kinetic variables associated with human locomotion, the literature currently provides few if any discussions regarding the dynamics of locomotion on surfaces that are either rocky or uneven. The purpose of this study was to investigate a method for using force plates to measure the ground reaction forces (GRFs) during gait on ballast. Ballast is a construction aggregate of unsymmetrical rock used in industry for the purpose of forming track bed on which railway ties are laid or in yards where railroad cars are stored. It is used to facilitate the drainage of water and to create even running surfaces. To construct the experimental ballast surfaces, 31.75-mm (1¼-in.) marble ballast at depths of approximately 63.5 mm (2.5 in.) or 101.6 mm (4 in.) were spread over a carpeted vinyl tile walkway specially designed for gait studies. GRF magnitudes and time histories from a force plate were collected under normal smooth surface and under both ballast surface conditions for five subjects. GRF magnitudes and time histories during smooth surface walking were similar to GRF magnitudes and time histories from the two ballast surface conditions. The data presented here demonstrate the feasibility of using a force plate system to expand the scope of biomechanical analyses of locomotion on ballast surfaces.


2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Amitava Halder ◽  
Chuansi Gao ◽  
Michael Miller

The effects of cooling on neuromuscular function and performance during gait are not fully examined. The purpose of this study was to investigate the effects of local cooling for 20 min in cold water at 10°C in a climate chamber also at 10°C on maximal isometric force and electromyographic (EMG) activity of the lower leg muscles. Gait ground reaction forces (GRFs) were also assessed. Sixteen healthy university students participated in the within subject design experimental study. Isometric forces of the tibialis anterior (TA) and the gastrocnemius medialis (GM) were measured using a handheld dynamometer and the EMG was recorded using surface electrodes. Ground reaction forces during gait and the required coefficient of friction (RCOF) were recorded using a force plate. There was a significantly reduced isometric maximum force in the TA muscle (P<0.001) after cooling. The mean EMG amplitude of GM muscle was increased after cooling (P<0.003), indicating that fatigue was induced. We found no significant changes in the gait GRFs and RCOF on dry and level surface. These findings may indicate that local moderate cooling 20 min of 10°C cold water, may influence maximal muscle performance without affecting activities at sub-maximal effort.


Author(s):  
Aydin Valizadeh orang ◽  
Arefeh Mokhtari Malekabadi ◽  
AmirAli Jafarnezhadgero

Background:Walking is one the common daily activities. With the beginning of middle age, weakness in the lower limb muscles can reduce the ability to walk. The use of foot orthoses reduce the load on the limbs and supports the joints during walking. The purpose of the present study was to investigate the acute effect of foot orthoses on the frequency spectrum of ground reaction forces during walking in the older adults. Methods: In this semi-experimental and laboratory study, 21 elderly (15 females and 6 males) with a mean height of 164.19±4.26 centimeters and weight of 80.04±3.50 kg, and age of 66.00±3.50 years were volunteered to participate in the study. The walking trials were done during three conditions including walking without foot orthoses, walking with small and large textured orthoses. The Bertec force plate (made in USA) with dimensions of 40 * 60 cm was used to record ground reaction forces. Results: The results of this study did not show any significant differences between walking without foot orthoses, walking with small and large textured foot orthoses for frequency of 99.5%, median frequency, frequency band and number of essential harmonics (P>0.05). However, the comfort level during wearing of large texture insole condition significantly increased compared to other conditions (P<0.05). Conclusion: The textured foot orthoses do not affect the frequency spectrum of ground reaction forces; however, it improves the comfort of the individual while walking.


Sign in / Sign up

Export Citation Format

Share Document