scholarly journals Update: Gender differences in CABG outcomes—Have we bridged the gap?

PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0255170
Author(s):  
Robina Matyal ◽  
Nada Qaisar Qureshi ◽  
Syed Hamza Mufarrih ◽  
Aidan Sharkey ◽  
Ruma Bose ◽  
...  

Background Appreciation of unique presentation, patterns and underlying pathophysiology of coronary artery disease in women has driven gender based risk stratification and risk reduction efforts over the last decade. Data regarding whether these advances have resulted in unequivocal improvements in outcomes of CABG in women is conflicting. The objective of our study was to assess gender differences in post-operative outcomes following CABG. Methods Retrospective analyses of institutional data housed in the Society of Thoracic Surgeons (STS) database for patients undergoing CABG between 2002 and 2020 were conducted. Multivariable regression analysis was conducted to investigate gender differences in post-operative outcomes. P-values were adjusted using Bonferroni correction to reduce type-I errors. Results Our final cohort of 6,250 patients had fewer women than men (1,339 vs. 4,911). more women were diabetic (52.0% vs. 41.2%, p<0.001) and hypertensive (89.1% vs. 84.0%, p<0.001). Women had higher adjusted odds of developing ventilator dependence >48 hours (OR: 1.65 [1.21, 2.45], p = 0.002) and cardiac readmissions (OR: 1.56 [1.27, 2.30], p = 0.003). After adjustment for comorbidity burden, mortality rates in women were comparable to those of age-matched men. Conclusion The findings of our study indicate that despite apparent reduction of differences in mortality, the burden of postoperative morbidity is still high among women.

Methodology ◽  
2015 ◽  
Vol 11 (3) ◽  
pp. 110-115 ◽  
Author(s):  
Rand R. Wilcox ◽  
Jinxia Ma

Abstract. The paper compares methods that allow both within group and between group heteroscedasticity when performing all pairwise comparisons of the least squares lines associated with J independent groups. The methods are based on simple extension of results derived by Johansen (1980) and Welch (1938) in conjunction with the HC3 and HC4 estimators. The probability of one or more Type I errors is controlled using the improvement on the Bonferroni method derived by Hochberg (1988) . Results are illustrated using data from the Well Elderly 2 study, which motivated this paper.


2020 ◽  
Vol 26 ◽  
Author(s):  
Maria Bergami ◽  
Marialuisa Scarpone ◽  
Edina Cenko ◽  
Elisa Varotti ◽  
Peter Louis Amaduzzi ◽  
...  

: Subjects affected by ischemic heart disease with non-obstructive coronary arteries constitute a population that has received increasing attention over the past two decades. Since the first studies with coronary angiography, female patients have been reported to have non-obstructive coronary artery disease more frequently than their male counterparts, both in stable and acute clinical settings. Although traditionally considered a relatively infrequent and low-risk form of myocardial ischemia, its impact on clinical practice is undeniable, especially when it comes to infarction, where the prognosis is not as benign as previously assumed. Unfortunately, despite increasing awareness, there are still several questions left unanswered regarding diagnosis, risk stratification and treatment. The purpose of this review is to provide a state of the art and an update on current evidence available on gender differences in clinical characteristics, management and prognosis of ischemic heart disease with non-obstructive coronary arteries, both in the acute and stable clinical setting.


2020 ◽  
Vol 39 (3) ◽  
pp. 185-208
Author(s):  
Qiao Xu ◽  
Rachana Kalelkar

SUMMARY This paper examines whether inaccurate going-concern opinions negatively affect the audit office's reputation. Assuming that clients perceive the incidence of going-concern opinion errors as a systematic audit quality concern within the entire audit office, we expect these inaccuracies to impact the audit office market share and dismissal rate. We find that going-concern opinion inaccuracy is negatively associated with the audit office market share and is positively associated with the audit office dismissal rate. Furthermore, we find that the decline in market share and the increase in dismissal rate are primarily associated with Type I errors. Additional analyses reveal that the negative consequence of going-concern opinion inaccuracy is lower for Big 4 audit offices. Finally, we find that the decrease in the audit office market share is explained by the distressed clients' reactions to Type I errors and audit offices' lack of ability to attract new clients.


2021 ◽  
Vol 13 (11) ◽  
pp. 6148
Author(s):  
Nicolás Bronfman ◽  
Paula Repetto ◽  
Paola Cordón ◽  
Javiera Castañeda ◽  
Pamela Cisternas

Previous studies have reported differences between men and women in the adoption of preventive behaviors against infectious diseases. This study aims to examine gender differences on a set of psychosocial factors shown to influence preventive behaviors against infectious diseases such as COVID-19. We conducted a web survey (N = 1.004) a few weeks after the end of the peak of the first wave of infections in Chile. The survey assessed participants’ perception of risk and worry about the COVID-19 pandemic, confidence in the government’s competence and integrity in dealing with the crisis, attribution of responsibility to various stakeholders, and adoption of preventive behaviors such as hygiene, distancing, and information-seeking. Our results confirm significant gender-based differences for both the psychosocial factors and the adoption of preventive behaviors. We conclude that women show a higher level of worry and fear of the pandemic and are keener to adopt preventive hygiene and social distancing behaviors. Similarly, participants report a low level of trust in government authorities, with women reporting the lowest trust level. The implications of these findings for the design of future risk communication strategies are discussed.


2021 ◽  
Vol 13 (3) ◽  
pp. 411-430

The current paper aimed to investigate taboo language using animal names in Facebook Messenger in the Jordanian setting based on the context where it appeared. A total of (100) male and female university students answered a questionnaire devised to examine the way how students use taboo language. It was noticed that "pig" recorded the highest frequency of occurrence comprising (11.59) of the total number of the taboo words followed by "dog" and "bitch". Important differences were observed in the frequency and use of taboo words by male (68. 8 %) and female (32.2%) students. The study explained the reasons why such words were deemed taboo in the Jordanian setting taking into consideration the socio-cultural and religious norms of the society. The study also concluded that taboo language was used to express different themes such as humor, relaxation, anger and abuse. Keywords: Taboo Language, Gender Differences, Themes, Socio-Pragmatic, Facebook Messenger.


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