scholarly journals The effect of camel milk curd masses on rats blood serum biochemical parameters: Preliminary study

PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0256661
Author(s):  
Fatima Dikhanbayeva ◽  
Elmira Zhaxybayeva ◽  
Zhuldyz Smailova ◽  
Arman Issimov ◽  
Zhechko Dimitrov ◽  
...  
Keyword(s):  
Blood Serum ◽  
Total Protein ◽  
Biochemical Parameters ◽  
Camel Milk ◽  
Control Group ◽  
Serum Biochemical Parameters ◽  
Group V ◽  
Group I ◽  
Serum Biochemical ◽  
Group Ii

This study aimed to assess potential feeding effect of camel milk curd mass and its mixes to experimental rat’s blood serum biochemical parameters, enzymatic activity and the peptide toxicity. Fifty healthy male Sprague-Dawley rats were divided into five groups (n = 10 each). Each group was fed with camel milk pure curd mass and its mixes for 16 days. At the end of the experiment, rats were sacrificed to collect the samples from the blood serum. Blood serum biochemical parameters total protein, cholesterol, glucose, albumin, triglycerides; the enzymatic activities of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase were determined on the A25 automatic analyser, and peptide toxicity analysed by the reference method. The statistical data have shown no significant differences in body weight gain in all groups. Total protein decreased in group II, IV, and V; however, it increased in group III compared to the control group. Cholesterol grew up in group II and it slightly increased in group V, dropped in groups III and IV compared to group I result. Glucose increased in groups II, III, IV compared to group I; still, group V results show a slight decrease. Albumin decreased in group IV, yet in group V it increased than the group I result. Simultaneously, groups II and III results were changed with less percentage. Triglyceride grew up in groups II, V, and it dropped significantly in groups III, IV compared to the control group. De Ritis ratio of enzymes in groups II, III, and IV fluctuated between 1.31 and 0.98 IU/L; however, group V demonstrated significant data versus group I. Diets peptide toxicity in all groups was lower than control group data. The experimental results indicated that curd mass from camel milk could be used as a pure or with additives and it did not discover the observed side effects.

Effects of xylene and formaldehyde inhalations on renal oxidative stress and some serum biochemical parameters in rats

2007 ◽  
Vol 23 (2) ◽  
pp. 115-120 ◽  
Author(s):  
Cavit Kum ◽  
Selim Sekkin ◽  
Funda Kiral ◽  
Ferda Akar
Keyword(s):  
Oxidative Stress ◽  
Total Protein ◽  
Biochemical Parameters ◽  
Control Group ◽  
Serum Biochemical Parameters ◽  
Sprague Dawley ◽  
Group 4 ◽  
Sprague Dawley Rats ◽  
Serum Biochemical ◽  
Group 2

In this study, it was aimed to demonstrate the possible renal oxidative stress and some serum biochemical parameters and their alterations caused by the exposure to xylene and formaldehyde (HCHO) in rats. Weighing 150—200 g, 12-week-old, 24 female Sprague-Dawley rats were used. The rats were randomly divided into four groups: Group 1 (control), Group 2 (300-ppm technical xylene), Group 3 (6-ppm HCHO) and Group 4 (150-ppm technical xylene + 3-ppm HCHO). The animals were exposed to gases eight hours per day for six weeks. Superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px) activities, glutathione (GSH) and malondialdehyde (MDA) levels were measured. In addition, serum total protein, albumin, urea and creatinine levels were evaluated. Compared with the control animals, urea levels increased significantly in all groups ( P < 0.001). GSH activities and MDA levels increased in xylene and xylene + HCHO groups ( P < 0.05). No statistically considerable differences were found in SOD, CAT and GSH-Px activities, total protein, albumin and creatinine levels among all groups ( P > 0.05). The present study indicates but not statistically confirms the renal toxicity of the exposures to xylene, HCHO and a mixture of them.

scholarly journals Age – Related changes in serum biochemical parameters in the domestic rabbit (Oryctolagus cuniculus)

2020 ◽  
Vol 45 (5) ◽  
pp. 67-71
Author(s):  
K. A. Adebisi
Keyword(s):  
Total Protein ◽  
Biochemical Parameters ◽  
Serum Biochemistry ◽  
Serum Biochemical Parameters ◽  
Serum Total Protein ◽  
Domestic Rabbit ◽  
Age Related ◽  
Protein 4.2 ◽  
Pubertal Stages ◽  
Serum Biochemical

The influence of age on serum biochemical components in the domestic rabbit was investigated. The serum total protein (g/dL), albumin (g/dL), globulin (g/dL), creatinine (mg/dL), urea mg/dL, cholesterol (mg/dL), Alkaline phosphatase (ALP; iu/l), Aspartate aminotranferase (AST; iu/l) and Alanine amimotransferase (ALT; iu/l) were assessed in 24 male rabbits at 7, 14 and 21 weeks of age to represent weaners, growers and pubertal stages. Data were analysed using descriptive statistics and analysis of variance at á . Results of 0.05 serum biochemistry revealed a steady significant increase in total protein (4.2±0.3; 5.3±0.5; 6.9±0.2), albumin (2.2±0.7; 2.8±0.4; 4.0±0.2), globulin (1.9±0.3; 2.5±0.4, 2.9±0.2), cholesterol (49.5±1.1; 56.4±4.2; 62.4±5.4) and creatinine (0.8±0.1; 1.2±0.1; 1.9±0.3) at 7, 14 and 21 weeks respectively. Serum urea levels were similar across the ages. The values recorded for ALP and AST at 7 weeks (39.6±7.5; 101.1±6.7) and 14 weeks (38.7±6.4; 104.5±8.7) were significantly higher than the 21 weeks (33.5±2.7; 95.8±5.9) while ALT at 7 weeks (27.33±5.6) was significantly lower than 14 (38.2±3.9) and 21 weeks (37.4±3.0). The age of the rabbits had a significant effect on their serum biochemical parameters. They should therefore be grouped according to age when setting serum reference values for them.

scholarly journals AMELIORATION OF GENTAMICIN-INDUCED RENAL DAMAGE IN RATS BY ETHANOL EXTRACT OF THE WHOLE PLANT BIOPHYTUM SENSITIVUM (LINN.) DC

2018 ◽  
Vol 10 (5) ◽  
pp. 130
Author(s):  
Abhirama B. R. ◽  
Shanmuga Sundaram R ◽  
Raju A
Keyword(s):  
Body Weight ◽  
Water Intake ◽  
Total Protein ◽  
Urine Volume ◽  
Ethanol Extract ◽  
Group Iv ◽  
Control Group ◽  
Group I ◽  
Whole Plant ◽  
Group Ii

Objective: Present study was undertaken to investigate the nephroprotective activity of whole plant ethanol extract of Biophytum sensitivum Linn. DC (B. sensitivum; EEBS) on gentamicin induced-nephrotoxicity in Wistar albino rats.Methods: Animals were divided into five groups, containing six animals in each. Gentamicin (GM) 100 mg/kg/d; i. p., was given to all groups except normal control to induce nephrotoxicity for a period of 8 d in rats. Animals in Group I served as control and Group II as GM-treated or nephrotoxic control. Group III received standard quercetin (50 mg/kg; p. o.); group IV received EEBS (250 mg/kg; p. o.) and group V received EEBS (500 mg/kg; p. o.), for 8 d. Several renal functional tests and injury markers such as a change in body weight, water intake, urine volume and pH, urinary levels of total protein, albumin, sodium, potassium, calcium and magnesium were measured. Different hematological parameters including, red blood cells (RBC), hemoglobin (Hb), packed cell volume (PCV), mean corpuscular haemoglobin (MCH), white blood corpuscles (WBC), lymphocyte, monocyte, polymorphs and eosinophil were also analyzed.Results: The results revealed that co-administration of EEBS at 250 and 500 mg/kg significantly reduced the urinary excretion of total protein (4.05±0.04, 3.53±0.05 g/dl), albumin (0.81±0.08, 0.71±0.00 g/dl), calcium (8.05±0.05, 7.81±0.06 mg/dl) and magnesium (0.79±0.05, 0.77±0.06 mg/dl) respectively. EEBS treatment in group IV and V animals produced a significant increase in body weight (2.58±0.17, 2.52±0.22 g), water intake (17.35±0.82, 17.87±0.86 ml/24 h) urine output (7.24±0.15, 7.88±0.08 ml/24 h), compared to animals in group II. Co-therapy with both doses of extracts also showed significant increase in RBC (6.85±0.31, 7.10±0.43 million/mm3) Hb (13.96±0.21, 13.83±0.31 g/dl), MCH (20.45±0.49, 20.67±0.51 pg) and PCV (38.29±0.42, 38.53±0.20%) levels, whereas WBC (8.24±0.21, 8.15±0.10 1X103/mm3) and polymorphs (14.19±0.20, 14.05±0.11%) levels were found to be significantly reduced respectively in animals than those in toxic control group.Conclusion: This study substantiated and confirmed the ethnomedical usefulness of B. sensitivum as a nephroprotective and antioxidant agent.

scholarly journals The Effect of Dietary Camelina Sativa Oil on Quality of Broiler Chicken Meat / Wpływ Udziału Oleju Z Lnianki Siewnej (Camelina Sativa) W Dawkach Dla Kurcząt Rzeźnych Na Jakość Mięsa

2013 ◽  
Vol 13 (4) ◽  
pp. 869-882 ◽  
Author(s):  
Mariusz P. Pietras ◽  
Sylwia Orczewska-Dudek
Keyword(s):  
Total Cholesterol ◽  
Total Protein ◽  
Broiler Chickens ◽  
Rapeseed Oil ◽  
Camelina Sativa ◽  
Control Group ◽  
Breast Meat ◽  
Camelina Oil ◽  
Group I ◽  
Group Ii

Abstract An experiment was conducted on 600 broiler chickens to determine the effect of using Camelina sativa oil as a dietary component on meat quality indicators. Broiler chickens were raised on litter under standard conditions of feeding and maintenance. In the second period of rearing, the control group (I) received a diet containing 6% rapeseed oil. Experimental groups were fed on a diet containing 3% rapeseed oil and 3% Camelina sativa oil (group II) and 6% camelina oil (group III). At the end of rearing 8 chickens from each group were slaughtered. A simplified analysis of the carcasses was conducted. Blood samples were taken to determine the content of total fat, triglycerides, total cholesterol and its fractions. Muscle samples were analysed for the content of dry matter, total protein and crude fat, fatty acid composition and malonic aldehyde (TBA). The meat was subjected to sensory evaluation. It was found that the introduction of Camelina sativa oil to the grower diet for broiler chickens does not have a negative effect on rearing parameters and carcass quality. What was observed was a tendency to reduce the proportion of abdominal fat in the carcass with increasing level of oil used in compound feed and increases in the total protein content of breast meat in group II receiving 3% of camelina oil. The addition of 6% of Camelina sativa oil to compound feed significantly decreased the content of total cholesterol and its fractions in the blood plasma of chickens in comparison to the other groups. The introduction of 3% and 6% of Camelina sativa oil to chicken diets enriched the breast meat in n-3 PUFA, mainly α-linolenic acid (ALA) and did not impair the flavour qualities of the cooked meat. The meat from chickens fed on a diet containing 6% of camelina oil was characterized by a greater increase of ALA.

scholarly journals Effect of organic and mineral selenium sources on production performance and selected physiological indicators in swine

2017 ◽  
Vol 73 (12) ◽  
pp. 756-763
Author(s):  
Anna Szuba-Trznadel ◽  
Tomasz Hikawczuk ◽  
Adam Ciura ◽  
Bogusław Fuchs
Keyword(s):  
Amino Acid ◽  
Blood Serum ◽  
Production Performance ◽  
Control Group ◽  
Lactation Period ◽  
Feed Conversion ◽  
Group Iii ◽  
Group I ◽  
Acid Chelate ◽  
Group Ii

The study was conducted on sows (hybrids of wbp × pbz breeds) and their offspring (until day 75 of life) kept on a farm. The aim of the experiment was to compare the effects of different sources of selenium (Se) on the production performance of the animals, Se content in their blood, the level of Se in sow’s colostrum, as well as Gpx, haptoglobin and immunoglobulin levels in the serum of sows and their offspring. Experimental feed mixtures for pregnant sows (LP), lactating sows (LK) and piglets (prestarter and starter) in each treatment had an identical basic composition, differing only in the type of selenium forms. Group I received a mineral form of Se in an amount of 0.2 mg/kg; group II received a mixture of a Se amino acid chelate and the mineral form of Se (0.1 mg/kg of each); group III received a Se amino acid chelate (0.2 mg/kg), and group IV received Se-enriched yeasts (0.2 mg/kg). Beneficial effects of the organic forms of Se were evident already in the lactation period. Sows, especially those from group II receiving 0.2 mg/kg of organic Se, had a higher feed intake, which was related to a higher milk production during lactation. As a result, on the weaning day, piglets from this group were significantly heavier than the other piglets. After weaning, as well, the piglets in this group were significantly heavier. These results were confirmed by parameters of blood serum and whey colostrum. Selenium as a chelate was more available than the mineral and enriched yeast forms. For this reason, the animals receiving the chelate were healthier (fewer inflammations were noted). The animals in this group also showed a better feed conversion compared with the others. The Gpx level in sows’ serum varied depending on the treatment. The highest level of this parameter was determined in sows from group III (receiving 0.2 mg/kg of organic Se), and it differed significantly from its value in the control group. The results showed that the Gpx level was related to the Se concentration in blood serum, which was also confirmed by a higher production of selenocysteine (a part of Gpx). Cells of the animals from this group were better protected against free radicals. Administration of 0.1 mg/kg of organic Se positively affects the performance of animals, but the recommended level in feed is 0.2 mg/kg of a selenium-containing amino acid....

scholarly journals Influence of salicylate administration on weight gain and serum biochemical parameters in broiler chickens

2010 ◽  
Vol 66 (10) ◽  
pp. 675-679 ◽  
Author(s):  
Poźniak B. ◽  
Yuan H. ◽  
J. Yi ◽  
Guo C. ◽  
Deng S. ◽  
...  
Keyword(s):  
Body Weight ◽  
Total Protein ◽  
Biochemical Parameters ◽  
Broiler Chickens ◽  
Clinical Manifestations ◽  
Weight Ratio ◽  
Serum Biochemical Parameters ◽  
Serum Total Protein ◽  
Weight Gains ◽  
Serum Biochemical

The aim of the study was to investigate the effects of different doses of acetylsalicylic acid (ASA) and sodium salicylate (SS) administration on weight gains and serum biochemical parameters in broiler chickens. This study was performed to investigate the safety of ASA and SS in chickens in conditions of moderate overdose. Seventy five broiler chickens (Sanhuangji breed) were divided into control and experimental groups. The chickens were administered orally with ASA or SS in the following daily doses: 50, 100 and 200 mg/kg for 20 days. In the course of the experiment weight gains were recorded. On day 14 and day 20 the chickens were sampled for blood biochemical analysis. Investigated parameters included serum total protein, albumin, uric acid, creatinine, potassium, sodium and calcium contents as well as alanine transaminase activity. After the last samplings the chickens were dissected and liver and kidney to body weight ratios were recorded. It was demonstrated that SS at a dose of 200 mg/kg increased serum total protein level. ASA increased serum proteins at a dose of 100 mg/kg but not at a higher dose. At the dose of 200 mg/kg ASA increased the kidney to body weight ratio. In all salicylate treated groups the liver weights were lower as compared to the control. No clinical manifestations of intolerance were observed. It is assumed that chickens tolerate ASA and SS well, even in doses producing distinct side effects in several mammalian species.

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