Multicentric Reticulohistiocytosis - A Rare Clinicopathological Entity

This is a rare case report of a thirty-eight-year-old male who presented with multiple asymptomatic hyper-pigmented papulonodular lesions on the face for the past two years without the association of pain or pruritus and with restriction of elbow movements. The diagnosis of multicentric reticulohistiocytosis was made on histopathological findings of Touton type of giant cells and sheets of foamy histiocytes along with immunohistochemistry (IHC) studies. Workup was done for other associated diseases. Multicentric reticulohistiocytosis (MRH) is also known as lipoid dermatitis,1 a rare disease which is characterised by the presence of extensive papulonodular cutaneous eruptions and severe, sometimes destructive arthropathy, followed by eruption of the skin and mucous membrane lesion.2,3 It’s a rare idiopathic nonLangerhans cell histiocytosis.4 This disorder is characterised by predominant cutaneous manifestation and joint involvements. The lesions may show regression and recurrence, many case studies show an association of this lesion with internal malignancies, autoimmune diseases, hyperlipidaemias, and tuberculosis.5,6 Few cases have shown musculoskeletal involvement with features such as myositis. The disease was described initially as reticulocytosis granuloma in 1952 by Caro and Senear, later the term was coined by Goltz and Laymon as multicentric reticulohistiocytosis in 1954.4 It is also known by different names such as giant cell histiocytosis, lipoid dermato-arthritis, lipoid-rheumatism and reticulohistiocytosis granuloma. The disease incidence is very low worldwide, less than 200 cases have been reported in literature5 and reports from India are limited.

Download Full-text

Mixed Cutaneous Infection Caused byMycobacterium szulgaiandMycobacterium intermediumin a Healthy Adult Female: A Rare Case Report

Case Reports in Dermatological Medicine ◽

10.1155/2015/607519 ◽

2015 ◽

Vol 2015 ◽

pp. 1-4 ◽

Cited By ~ 3

Author(s):

Amresh Kumar Singh ◽

Rungmei S. K. Marak ◽

Anand Kumar Maurya ◽

Manaswini Das ◽

Vijaya Lakshmi Nag ◽

...

Keyword(s):

Case Report ◽

Rare Case ◽

Healthy Adult ◽

Nontuberculous Mycobacteria ◽

Anterior Abdominal Wall ◽

Cutaneous Infection ◽

Once Daily ◽

The Past ◽

Rare Case Report

Nontuberculous mycobacteria (NTMs) are ubiquitous and are being increasingly reported as human opportunistic infection. Cutaneous infection caused by mixed NTM is extremely rare. We encountered the case of a 46-year-old female, who presented with multiple discharging sinuses over the lower anterior abdominal wall (over a previous appendectomy scar) for the past 2 years. Microscopy and culture of the pus discharge were done to isolate and identify the etiological agent. Finally, GenoType Mycobacterium CM/AS assay proved it to be a mixed infection caused byMycobacterium szulgaiandM. intermedium. The patient was advised a combination of rifampicin 600 mg once daily, ethambutol 600 mg once daily, and clarithromycin 500 mg twice daily to be taken along with periodic follow-up based upon clinical response as well as microbiological response. We emphasize that infections by NTM must be considered in the etiology of nonhealing wounds or sinuses, especially at postsurgical sites.

Download Full-text

Bilateral Sturge Weber Syndrome- a rare case report

Nepalese Journal of Ophthalmology ◽

10.3126/nepjoph.v5i1.7841 ◽

2013 ◽

Vol 5 (1) ◽

pp. 129-132 ◽

Cited By ~ 1

Author(s):

P Singh ◽

S Singh

Keyword(s):

Case Report ◽

Rare Case ◽

Unusual Case ◽

The Other ◽

Advanced Stage ◽

Weber Syndrome ◽

Rare Case Report ◽

The Face ◽

Bilateral Condition ◽

Sturge Weber Syndrome

Background: Sturge-Weber syndrome is a rare congenital neuro- oculo- cutaneous disorder. Objective: To report a very rare unusual case of bilateral manifestation of Sturge Weber syndrome. Case: We report an unusual case of a 17-year-old female with advanced stage of bilateral glaucoma associated with facial nevus extending to the other half of the face as well and bilateral intracranial calcification. Conclusion: Sturge -Weber syndrome can manifest as a bilateral condition. Nepal J Ophthalmol 2013; 5(9):129-132 DOI: http://dx.doi.org/10.3126/nepjoph.v5i1.7841

Download Full-text

Solitary Trichoepithelioma of Nose: A Rare Case Report and Review of Literature

International Journal of Head and Neck Surgery ◽

10.5005/jp-journals-10001-1237 ◽

2015 ◽

Vol 6 (3) ◽

pp. 115-117

Author(s):

Sachin Lal Shilpakar ◽

Bivek Aryal ◽

Shyam Thapa Chettri ◽

Apar Pokharel ◽

Deepak Paudel

Keyword(s):

Case Report ◽

Rare Case ◽

Histopathological Examination ◽

Hair Follicles ◽

Review Of Literature ◽

Solitary Lesion ◽

Biological Potential ◽

Rare Case Report ◽

The Face ◽

Head Neck

ABSTRACT The trichoepithelioma is a benign cutaneous neoplasm which is derived from hair follicles. It is common in the face, but there are only three reports of the solitary occurrence on the nose. It is often not recognized because of its rarity, controversial classification, origin and biological potential. The objective of this paper is to present a case of solitary trichoepithelioma on the nose, histopathological examination and treatment. It should be considered as a differential diagnosis of a solitary lesion of nose which is confused with basal cell carcinoma. The confirmation by histopathological examination is essential. How to cite this article Sah BP, Shilpakar SL, Aryal B, Chettri ST, Pokharel A, Mishra S, Paudel D. Solitary Trichoepithelioma of Nose: A Rare Case Report and Review of Literature. Int J Head Neck Surg 2015;6(3):115-117.

Download Full-text

Psoriasiform Mycosis Fungoides Involving the Face- A Rare Case Report

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i53a33643 ◽

2021 ◽

pp. 94-99

Author(s):

N. R. Vignesh ◽

Shreya Srinivasan ◽

G. Sukanya ◽

S. Arun Karthikeyan

Keyword(s):

Case Report ◽

Mycosis Fungoides ◽

Rare Case ◽

Cell Lymphoma ◽

Punch Biopsy ◽

Cutaneous T Cell Lymphoma ◽

Rare Presentation ◽

Rare Case Report ◽

Atypical Cells ◽

The Face

Mycosis fungoides is represented as the most common epidermotropic cutaneous T-cell lymphoma, which is mainly characterized by the proliferation of atypical cells within the epidermis. We report a rare presentation of mycosis fungoides in a 60-year-old male presenting with chronic psoriasiform plaque involving the face. Punch biopsy of the lesion from the forehead was taken for routine histological examination and immunohistochemical stains. Results of biopsy and immunohistochemical findings were consistent with mycosis fungoides and diagnosed as psoriasiform presentation of mycosis fungoides involving the face.

Download Full-text

STURGE WEBER SYNDROME- A RARE CASE REPORT ORIGINAL

10.36106/ijar/9502925 ◽

2021 ◽

pp. 4-5

Author(s):

Om Prakash Singh ◽

Vikas Kumar ◽

Pushp Kant Tiwari

Keyword(s):

Rare Case ◽

Signs And Symptoms ◽

Port Wine ◽

Occipital Area ◽

Weber Syndrome ◽

Rare Case Report ◽

The Face ◽

Sturge Weber Syndrome ◽

The Brain ◽

Embryonic Vessels

Sturge-Weber Syndrome (SWS) is one of the encephalotrigeminal angiomatosis and one of the important segmental vascular neurocutaneous disorders .The occurrence is not very uncommon and the prevalence is 1:20000 to 1:50000.(1) SWS occurs due to the presence of residual embryonic vessels . The various signs and symptoms include capillary malformation in the face a port wine birthmark and similar malformation in the brain involving leptomeniges as well as blood vessels of the eye causing glaucoma. The patient presents with seizures , hemiparesis and stroke like symptoms, headaches and developmental delay.(2) The imaging nding in SWS children is the calcication in the parietal and occipital area of the brain. The EEG ndings in SWS are the attenuation and the excess of slow activities.We are presenting here a rare case of , a fourteen year old male child who presented to our emergency department with status epilepticus. The aim of presenting this case is to share the classical presentation and the challenges involved in the management

Download Full-text

Jejunal Diverticular Perforation Causing Small Bowel Obstruction in a Type 4 Hiatal Hernia: A Rare Case Report of a Nonagenarian Patient and Review of Relevant Literature

Case Reports in Surgery ◽

10.1155/2017/8412927 ◽

2017 ◽

Vol 2017 ◽

pp. 1-4

Author(s):

Saptarshi Biswas ◽

Shekhar Gogna ◽

Prem Patel

Keyword(s):

Small Bowel ◽

Rare Case ◽

Epigastric Pain ◽

Relevant Literature ◽

Exploratory Laparotomy ◽

The Past ◽

Type Iv ◽

Intestinal Gas ◽

Mesenteric Side ◽

Rare Case Report

Type IV paraesophageal hernia (PEH) is very rare and is characterized by the intrathoracic herniation of the abdominal viscera other than the stomach into the chest. We describe a case of a 90-year-old male patient who presented at our emergency department complaining of epigastric pain that he had experienced over the past few hours and getting progressively worse. On the day after admission, his pain became severe. Chest radiography revealed an intrathoracic intestinal gas bubble; emergency exploratory laparotomy identified a type IV PEH with herniation of only the jejunum with perforated diverticula on mesenteric side through a hiatal defect into mediastinum. There are a few published cases of small bowel herniation into the thoracic cavity in the literature. Our patient represents a rare case of an individual diagnosed with type IV PEH with herniation of jejunum with perforated diverticula.

Download Full-text

Rare presentation of the great imitator: a rare case report

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20173929 ◽

2017 ◽

Vol 3 (3) ◽

pp. 453

Author(s):

Ravindranath Brahmadeo Chavan ◽

Vasudha Abhijit Belgaumkar ◽

Aarti Sudam Salunke ◽

Sharada Shivaji Chirame

Keyword(s):

Primary Care ◽

Health Care ◽

Rare Case ◽

Signs And Symptoms ◽

Rare Presentation ◽

The Past ◽

Modern Health Care ◽

Rare Case Report ◽

Life Threatening ◽

Primary Care Clinicians

<span>Syphilis is often thought to be a disease of the past, largely eradicated in modern health care; however, the rates are still extremely high in certain populations. The diagnosis of syphilis may be overlooked by primary-care clinicians due to the presence of nonspecific signs and symptoms that may be indistinguishable from other diseases. Left undiagnosed and untreated, life-threatening complications, including hepatitis, stroke, and nervous system damage, may occur particularly in immuno-compromised individuals. We present a case of lues maligna an extremely rare presentation of syphilis.</span>

Download Full-text

IDIOPATHIC GIANT CELL MYOCARDITIS PRESENTING AS SUDDEN CARDIAC DEATH- A RARE CASE REPORT

Journal of Health and Allied Sciences NU ◽

10.1055/s-0040-1703785 ◽

2014 ◽

Vol 04 (02) ◽

pp. 142-143

Author(s):

Harish S. Permi

Keyword(s):

Giant Cell ◽

Rare Case ◽

Plasma Cells ◽

Myocardial Necrosis ◽

Giant Cells ◽

Cellular Infiltration ◽

Healthy Male ◽

Giant Cell Myocarditis ◽

Unexplained Death ◽

Rare Case Report

Abstract:Idiopathic giant cell myocarditis is a disease of relatively young, predominantly healthy adults which is usually known to cause death in more than half of the cases of sudden death due to heart failure and ventricular arrhythmia. The typical histological features are myocardial necrosis and a rich cellular infiltration of lymphocytes, macrophages, eosinophils, plasma cells and multinucleated giant cells. We report a rare case of idiopathic giant cell myocarditis in a 32 year old healthy male who died suddenly and stress the need to consider as one of the cause of unexplained death in young adults on autopsy.

Download Full-text

Mucormycotic Osteomyelitis Involving the Maxilla: A Rare Case Report and Review of the Literature

Case Reports in Infectious Diseases ◽

10.1155/2019/8459296 ◽

2019 ◽

Vol 2019 ◽

pp. 1-6

Author(s):

Rajesh Arani ◽

S. N. H. Afsar Shareef ◽

H. M. Khuthija Khanam

Keyword(s):

Diabetes Mellitus ◽

Case Report ◽

Soft Tissue ◽

Rare Case ◽

Inflammatory Process ◽

Review Of The Literature ◽

The Past ◽

Rare Case Report ◽

Calcified Tissue ◽

Fungal Osteomyelitis

Osteomyelitis is an inflammatory process of bone and marrow contents. These changes in bone are primarily seen in soft tissue followed by calcified tissue. It is an opportunistic infection due to the complication of some other conditions rendering the host susceptible to disease. Consequences of this infection range from draining tract to malignant transformation. Various etiological factors are involved in origin of the disease; among them, fungal origin is rare. Specific feature in fungal osteomyelitis is the involvement of maxillary sinus with a complaint of sinusitis associated with diabetes mellitus. Here, we discuss a case of osteomyelitis with fungal infection involving the maxilla. The patient is under medication for the past five years due to diabetes.

Download Full-text