Federal clinical recommendations on diagnostics and treatment of Graves' disease in the children

2014 ◽  
Vol 60 (3) ◽  
pp. 59-68
Author(s):  
O B Bezlepkina

Graves' disease is rather rare occurrence in the childhood, with the girls being the most frequently affected gender. The draft clinical guidelines on diagnostics and treatment of Graves' disease in the children and adolescents are proposed for the extensive discussion. The guidelines are intended for pediatric endocrinologists, pediatrists, surgeons, and specialists in radioisotope therapy.

Author(s):  
Mohamed Masmoudi ◽  
Regaig Marwa ◽  
Thabet Wadii ◽  
Mehdi Hasnaoui ◽  
Mighri Khalifa

Author(s):  
M. R. Shaydullina ◽  
A. R. Shakirova ◽  
A. A. Zinatullina

Neonatal thyrotoxicosis is 1% of all cases of thyrotoxicosis in children and adolescents and it is mostly determined by the mother’s Graves’ disease. The most dangerous manifestations of neonatal thyrotoxicosis are intrauterine growth retardation, tachycardia, and heart rhythm disturbances. Timely diagnostics and beginning of treatment are of great importance due to the high risk of fatal cardiac disruption in the acute phase of the disease and its serious consequences for the body. The article presents a clinical case of a patient with neonatal thyrotoxicosis diagnosed only at the age of 1 month, despite the mother’s burdened anamnesis; it contains a plan for diagnostic search and tactics of child management.


PEDIATRICS ◽  
1986 ◽  
Vol 77 (6) ◽  
pp. 922-924
Author(s):  
JOHN P. GEARHART ◽  
FRANKLIN C. LOWE

Trauma to the lower genitourinary tract in children and adolescents has been a rare occurrence. However, with the advent of pediatric trauma centers, more of these injuries are now being seen and evaluated. Although trauma to the genitourinary tract alone is an uncommon cause of death, trauma centers are seeing more children in which decisions regarding the management of the genitourinary tract must be made. Most injuries that have been reported have been secondary to blunt trauma such as straddle injuries, falls, or motor vehicle accidents. Recently, two cases of lower genitourinary tract trauma have been seen associated with the current fad of break dancing.


2011 ◽  
Vol 35 (11) ◽  
pp. 2428-2431 ◽  
Author(s):  
C. Chiapponi ◽  
U. Stocker ◽  
Th. Mussack ◽  
J. Gallwas ◽  
K. Hallfeldt ◽  
...  

Author(s):  
Reuven Zev Cohen ◽  
Eric I. Felner ◽  
Kurt F. Heiss ◽  
J. Bradley Wyly ◽  
Andrew B. Muir

AbstractThe majority of pediatric patients with Graves’ disease will ultimately require definitive therapy in the form of radioactive iodine (RAI) ablation or thyroidectomy. There are few studies that directly compare the efficacy and complication rates between RAI and thyroidectomy. We compared the relapse rate as well as the acute and long-term complications of RAI and total thyroidectomy among children and adolescents with Graves’ disease treated at our center.Medical records from 81 children and adolescents with a diagnosis of Graves’ disease who received definitive therapy over a 12-year period were reviewed.Fifty one patients received RAI and 30 patients underwent thyroidectomy. The relapse rate was not significantly different between RAI and thyroidectomy (12.1% vs. 0.0%, p=0.28). There were no acute or long-term complications in the RAI group, but there were eight cases of hypoparathyroidism (two transient and six permanent) in the thyroidectomy group. None of the patients developed a recurrent laryngeal nerve injury.RAI is a safe and effective option for treatment of children and adolescents with Graves’ disease. In light of the rate of permanent hypoparathyroidism seen at our center with thyroidectomy and previously published long-term safety of RAI, we recommend RAI as the first line treatment for children and adolescents with Graves’ disease. For those centers performing thyroidectomies, we recommend that each center select 1–2 high-volume pediatric surgeons to perform all thyroid procedures, allowing individuals to increases case volume and potentially decrease long-term complications of thyroidectomy.


1985 ◽  
Vol 19 (6) ◽  
pp. 613-613
Author(s):  
Akimasa Okuno ◽  
Daisuke Ueda ◽  
Koichi Yano ◽  
Fumie Inyaku ◽  
Nozomu Sasaki ◽  
...  

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