Reference intervals for follicle-stimulating hormone, luteinizing hormone and prolactin in children and young adults on the bioMérieux Mini-Vidas system

2007 ◽  
Vol 45 (4) ◽  
Author(s):  
Thu Koskas ◽  
Karamo Souaré ◽  
Tarik Ouahabi ◽  
Dominique Porquet ◽  
Didier Chevenne
Keyword(s):  
Luteinizing Hormone ◽  
Pediatric Population ◽  
Follicle Stimulating Hormone ◽  
Reference Intervals ◽  
Age Group ◽  
Pubertal Stage ◽  
Significant Difference ◽  
Class 1 ◽  
Children And Young Adults ◽  
Stimulating Hormone

AbstractWe measured serum follicle-stimulating hormone (FSH), luteinizing hormone (LH) and prolactin concentrations on a bioMérieux Mini Vidas system in a pediatric population ranging in age from 1 to 19 years. Reference intervals were established separately for females and males, with stratification by age group and by Tanner's pubertal stage. FSH values were higher in females than in males, and were lowest in both sexes of age class 2 (4–8 years), increasing thereafter to the upper limit for stage PIV (females) and stage PV (males). LH values showed a similar pattern of change: concentrations were lowest for class 1 (1–3 years) and class 2 (4–8 years), and highest for stage PII (females) and stage PV (males). No significant difference was observed according to gender. Prolactin values did not differ markedly according to gender or pubertal status.Clin Chem Lab Med 2007;45:541–5.

Luteinizing hormone, follicle-stimulating hormone, testosterone and dihydrotestosterone during testicular descent in the pig fetus

1996 ◽  
Vol 8 (7) ◽  
pp. 1115 ◽  
Author(s):  
JH Visser ◽  
CF Heyns
Keyword(s):  
Luteinizing Hormone ◽  
Body Mass ◽  
Follicle Stimulating Hormone ◽  
Linear Increase ◽  
Testicular Descent ◽  
Serum Concentrations ◽  
Male And Female ◽  
Androgen Synthesis ◽  
Significant Difference ◽  
Stimulating Hormone

To investigate the relationship between gonadotrophins, androgens and testicular descent in the pig fetus, serum concentrations of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), and serum concentrations and testicular content of testosterone (T) and 5 alpha-dihydrotestosterone (DHT) were determined by radioimmunoassay in 95 fetuses (48 males, 47 females) between Day 60 and Day 90 post coitum (p.c.). The testes were descended in 0% of fetuses at Day 60, 8% of fetuses at Day 70, 40% of fetuses at Day 80 and 87% of fetuses at Day 90 p.c. There was a significant increase in mean serum concentrations of LH in both male and female fetuses from Day 60 to Day 90, with a significant difference in mean serum concentrations of LH between male fetuses with a body mass < 350 g (4% of testes descended) and those with a body mass > 450 g (87% of testes descended), but not between male and female fetuses < 350 g or > 450 g in body mass. There was no significant difference in mean serum concentrations of FSH between male and female fetuses. Mean serum concentrations of T were significantly higher in male fetuses at Day 60 than in those at Days 70-90, with no significant difference in serum concentrations of DHT from Day 60 to Day 90 p.c. Testicular content of T and DHT showed a non-linear increase from Day 60 to Day 90 p.c. Although the serum concentration of T is elevated before, and decreased during, the period of descent, the testicular content of T and DHT increases during the period of descent, indicating that serum concentrations of LH and FSH may have an indirect effect on descent by stimulating testicular androgen synthesis.

scholarly journals Prevalence of polycystic ovarian syndrome and its association with circulatory gonadotropins (luteinizing hormone and follicle-stimulating hormone) and prolactin in different reproductive age groups: A brief survey

2021 ◽  
Vol 2 ◽  
pp. 8
Author(s):  
Swastika Purohit ◽  
Seema Rai ◽  
Shubhada Kalvit
Keyword(s):  
Luteinizing Hormone ◽  
Polycystic Ovarian Syndrome ◽  
Follicle Stimulating Hormone ◽  
Age Groups ◽  
Reproductive Age ◽  
Age Group ◽  
Age Related ◽  
Circulatory Level ◽  
Ovarian Syndrome ◽  
Stimulating Hormone

Polycystic ovarian syndrome can affect fertility due to anovulatory cycles, luteal phase defects, hyperprolactinemia, and sex hormone imbalance, it remains untreated. The present study aims prevalence of polycystic ovarian disease (PCOD) of clinical/subclinical infertile women, different age groups and to analyze the association between circulatory level of gonadotropins, luteinizing hormone and follicle-stimulating hormone (LH and FSH) and prolactin (PRL) in polycystic ovary syndrome (PCOS) women of different reproductive age and its impact on fertility of women. The hormonal reports for LH, FSH, and PRL of 100 female patients were analyzed. Women suffering from oligomenorrhea and amenorrhea are given priority in this study. These samples were categorized into five different age groups of 15–20 years, 21–25 years, 26–30 years, 31–35 years, and 36–40 years. Obtained hormonal data of LH, FSH, and PRL were pooled and the average was taken to compare with the normal range of hormone. A significant age-dependent variation observed in circulatory serum levels of gonadotropins (LH and FSH) and PRL. The study reveals that the highest PCOD patients were observed in the age group of 21–25 years. Whereas, 30% to 15–20 years, 60% to 21–25 years, 40% to 26–30 years, 30 % to 31–35 years, and 20 % to 36–40 years of reproductive age group. Most affected population of PCOS women ranges in between 21 and 25 age groups, whereas the 36–40 age group was least affected. Age-related alteration in the circulatory level of PRL (hyperprolactinemia) and pulsatility of LH and FSH can be considered as the important factor regulating neuronal mechanisms of hypophyseal gonadal and peripheral endocrine feedback.

Age-specific reference intervals of serum anti-Müllerian hormone in Chinese girls

2021 ◽  
pp. 000456322110028
Author(s):  
Jin Wang ◽  
Ting Yao ◽  
Xinxin Zhang ◽  
Qi Chen ◽  
Shuo Gong ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Luteinizing Hormone ◽  
Body Mass ◽  
Follicle Stimulating Hormone ◽  
Reference Intervals ◽  
Specific Reference ◽  
Hormone Concentration ◽  
Healthy Chinese ◽  
Chinese Girls ◽  
Stimulating Hormone

Background This study aimed to establish anti-Mullerian hormone age-specific reference intervals and determine the correlation between the anti-Mullerian hormone concentration and age, body mass index and concentrations of follicle-stimulating hormones and luteinizing hormone in healthy Chinese girls. Methods Serum anti-Mullerian hormone concentrations of 1702 healthy girls (0−12 years), recruited between March 2018 and December 2019, were determined using the Beckman Access 2 automated chemiluminescence immunoassay. Single-year-specific medians of anti-Mullerian hormone and effects of age, body mass index, follicle-stimulating hormone and luteinizing hormone on anti-Mullerian hormone concentration were analysed. Results The anti-Mullerian hormone median level continued increasing from birth, reached its peak at age 9 at 4.45 ng/mL (interquartile range [IQR] 2.58–6.90) and then gradually decreased. At age 12, the median reached 1.98 ng/mL (IQR 1.05–3.46). Age-specific reference intervals for anti-Mullerian hormone were established in healthy Chinese girls aged 0–12 years. Anti-Mullerian hormone concentrations showed a moderately positive correlation with age (r = 0.33, P < 0.001). In contrast, follicle-stimulating hormone (r = –0.29, P < 0.001) concentrations were weakly negatively correlated with the serum anti-Mullerian hormone concentration. Conclusion We established single-year-specific reference intervals for anti-Mullerian hormone in Chinese girls using the Beckman chemiluminescent platform. This reference range can help clinicians accurately understand anti-Mullerian hormone secretion in healthy girls and promote its clinical use.

Some effects of level of feeding and body condition upon sperm production and gonadotropin concentrations in the ram

1982 ◽  
Vol 34 (3) ◽  
pp. 265-277 ◽  
Author(s):  
J. E. Alkass ◽  
M. J. Bryant ◽  
J. S. Walton
Keyword(s):  
Luteinizing Hormone ◽  
Anterior Pituitary ◽  
Reproductive Tract ◽  
Follicle Stimulating Hormone ◽  
Live Weight ◽  
Maintenance Requirement ◽  
Scrotal Circumference ◽  
Significant Difference ◽  
Pituitary Glands ◽  
Stimulating Hormone

ABSTRACT1. In two experiments. Scottish Blackface and Finnish Landrace ♂ × Dorset Horn ♀ rams were housed in light-proof buildings and subjected to a constant 10-h light: 14-h dark photoperiod 70 days before and during the experiment. In experiment 1, four rams from each breed type were given either 750kJ/MJ(L) or 1250 to 1500 kJ/MJ(H) of their maintenance requirement for 20 weeks. In experiment 2, four rams of each breed were given either 750kJ/MJ(T) or 2000 kJ/MJ(F) of their maintenance requirement for 20 weeks, and were then fed to maintain live weight for a further 10 weeks. Daily sperm output in the urine and scrotal circumference were measured in both experiments. Various characteristics of ejaculated semen were measured in experiment 1. Sequential blood samples were collected from the rams on both experiments and assayed for follicle stimulating hormone and luteinizing hormone. At the end of each experiment the rams were slaughtered, and their testes, epididymides and anterior pituitary glands recovered.2. In Experiment 1, the L feeding level depressed progressively the numbers of sperm voided in the urine, scrotal circumference, and the concentration and total numbers of sperm in ejaculated semen. The testes and epididymides of L rams were lighter (P<0·01) and fewer sperm were recovered from the reproductive tract than i n H rams (P<0·01). The pituitary glands were lighter (P<0·05) and contained less luteinizing hormone (P<0·01) but amounts of follicle stimulating hormone similar to the H rams. Plasma luteinizing hormone levels were lower in L than in H rams at 20 weeks (P<0·05).3. In experiment 2, the T rams showed a progressive depression of numbers of sperm in the urine and scrotal circumference, such that at 20 weeks differences between F and T treatments were statistically significant (P<0·05 and 001 respectively). Subsequently, some recovery occurred which, with a reduction in these measures on F treatments, led to there being no statistically significant difference at 30 weeks. There were no statistically significant differences between F and T treatments in testes and epididymes weights, total number of sperm in the tract, and anterior pituitary weight, follicle stimulating hormone and luteinizing hormone content.

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