scholarly journals Analysis of uterine electromyography signals using time-frequency based topological features for detection of preterm birth

2021 ◽  
Vol 7 (2) ◽  
pp. 867-870
Author(s):  
Vinothini Selvaraju ◽  
Karthick Pa ◽  
Ramakrishnan Swaminathan
Keyword(s):  
Preterm Birth ◽  
Topological Data Analysis ◽  
Time Frequency ◽  
Uterine Contractions ◽  
Topological Features ◽  
Global Priority ◽  
Significant Difference ◽  
Data Points ◽  
Gestational Week ◽  
Uterine Electromyography

Abstract Detection of preterm birth (gestational week < 37) is a global priority as it causes major health problems to neonates. Assessment of uterine contractions (burst) is required to detect and prevent the threat of preterm birth. Uterine electromyography (uEMG) is widely preferred to measure the uterine contractions noninvasively. These signals are nonstationary in nature. It can be handled by topological data analysis (TDA) effectively. Therefore, TDA can be used to explore the characteristics of uEMG burst signals. In this study, an attempt has been made to distinguish term (gestational week ≥ 37) and preterm conditions using timefrequency based topological features in uEMG burst signals. These signals are obtained from the publicly available online dataset. The annotated burst signals are segmented and subjected to a short time Fourier transform. The transformed real and imaginary Fourier coefficients are plotted in the complex plane and the envelope of the data points are computed using the alpha-shape technique. Four topological features such as, area, perimeter, circularity and ellipse variance are extracted. These features are statistically analyzed. The coefficient of variation (CoV) is calculated to measure the inter-subject variations. The results show that the proposed method is able to discriminate between term and preterm conditions. The extracted features namely, area and perimeter exhibit significant difference (p < 0.05) between these two conditions. The CoV of the perimeter is observed to be low, implying that this feature can handle inter-subject variations in burst signals. The extracted topological features are useful to analyze the characteristics of term and preterm pregnancies

scholarly journals Preterm Birth: A Prominent Risk Factor for Low Apgar Scores

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Maria Svenvik ◽  
Lars Brudin ◽  
Marie Blomberg
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Preterm Birth ◽  
Tertiary Care ◽  
Multiple Pregnancy ◽  
Apgar Scores ◽  
Significant Difference ◽  
Gestational Week ◽  
Using Data ◽  
Predictive Risk

Objective.To determine predictive risk factors for Apgar scores < 7 at 5 minutes at two hospitals providing tertiary care and secondary care, respectively.Methods.A retrospective registry cohort study of 21126 births (2006–2010) using data from digital medical records. Risk factors were analyzed by logistic regression analyses.Results.  AS5min⁡<7was multivariately associated with the following: preterm birth; gestational week 32 + 0–36 + 6,OR=3.9(95% CI 2.9–5.3); week 28 + 0–31 + 6,OR=8(5–12); week < 28 + 0,OR=15(8–29); postterm birth,OR=2.0(1.7–2.3); multiple pregnancy,OR=3.53(1.79–6.96); previous cesarean section,OR=3.67(2.31–5.81); BMI 25–29,OR=1.30(1.09–1.55);BMI≥30  OR=1.70(1.20–2.41); nonnormal CTG at admission,OR=1.98(1.48–2.66). ≥1-para was associated with a decreased risk forAS5min⁡<7,OR=0.34(0.25–0.47). In the univariate logistic regression analysisAS5min⁡<7was associated with tertiary level care,OR=1.48(1.17–1.87); however, in the multivariate analysis there was no significant difference.Conclusion.A number of partially preventable risk factors were identified, preterm birth being the most evident. Further, no significant difference between the two hospital levels regarding the risk for low Apgar scores was detected.

scholarly journals The effect of short pregnancy interval on perinatal outcomes in Turkey: A retrospective study

2019 ◽  
Vol 35 (5) ◽  
Author(s):  
Nevşen SARAL ◽  
Seval CAMBAZ ULAŞ
Keyword(s):  
Retrospective Study ◽  
Birth Weight ◽  
Preterm Birth ◽  
Low Birth Weight ◽  
Perinatal Outcomes ◽  
Creative Commons ◽  
Significant Difference ◽  
Research Population ◽  
Gestational Week ◽  
Birth Records

Objective: The aim of the study was to determine the effect of short pregnancy interval on perinatal outcomes. Methods: The research was a retrospective study. The material consisted of birth records of a state hospital for the last three years in Manisa in the western region of Turkey (2015-2017) (n:8961). The research population included women whose gestational interval was ≤two years and the gestational week was over 22 weeks (n:2089). Perinatal outcomes were assessed through preterm birth, stillbirth, and low birth weight. Results: The mean age of women who are in the research group is 26.7 ± 5.32. According to the perinatal results of women with a pregnancy interval of two years and shorter; 8.2% of women had birth before 37 weeks and 0.3% resulted in stillbirth. It was determined that 4.8% of infants were born with low birth weight. There was no difference between the short pregnancy interval and stillbirth or preterm birth. However, a significant difference was found between the low birth weight and short pregnancy interval. (p>0.05). Conclusions: Pregnancy interval does not affect preterm birth and stillbirth from perinatal outcomes, but has a significant effect on the birth weight of the newborn. doi: https://doi.org/10.12669/pjms.35.5.837 How to cite this:Saral N, Ulas SC. The effect of short pregnancy interval on perinatal outcomes in Turkey: A retrospective study. Pak J Med Sci. 2019;35(5):---------. doi: https://doi.org/10.12669/pjms.35.5.837 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Automated detection of preterm condition using uterine electromyography based topological features

2021 ◽  
Vol 41 (1) ◽  
pp. 293-305
Author(s):  
S. Vinothini ◽  
N. Punitha ◽  
P.A. Karthick ◽  
S. Ramakrishnan
Keyword(s):  
Automated Detection ◽  
Topological Features ◽  
Uterine Electromyography

scholarly journals Topological Data Analysis Approaches to Uncovering the Timing of Ring Structure Onset in Filamentous Networks

2021 ◽  
Vol 83 (3) ◽  
Author(s):  
Maria-Veronica Ciocanel ◽  
Riley Juenemann ◽  
Adriana T. Dawes ◽  
Scott A. McKinley
Keyword(s):  
Time Series ◽  
Data Analysis ◽  
Actin Filaments ◽  
Time Series Data ◽  
Polymer Networks ◽  
Topological Data Analysis ◽  
Series Data ◽  
Topological Features ◽  
Topological Data

AbstractIn developmental biology as well as in other biological systems, emerging structure and organization can be captured using time-series data of protein locations. In analyzing this time-dependent data, it is a common challenge not only to determine whether topological features emerge, but also to identify the timing of their formation. For instance, in most cells, actin filaments interact with myosin motor proteins and organize into polymer networks and higher-order structures. Ring channels are examples of such structures that maintain constant diameters over time and play key roles in processes such as cell division, development, and wound healing. Given the limitations in studying interactions of actin with myosin in vivo, we generate time-series data of protein polymer interactions in cells using complex agent-based models. Since the data has a filamentous structure, we propose sampling along the actin filaments and analyzing the topological structure of the resulting point cloud at each time. Building on existing tools from persistent homology, we develop a topological data analysis (TDA) method that assesses effective ring generation in this dynamic data. This method connects topological features through time in a path that corresponds to emergence of organization in the data. In this work, we also propose methods for assessing whether the topological features of interest are significant and thus whether they contribute to the formation of an emerging hole (ring channel) in the simulated protein interactions. In particular, we use the MEDYAN simulation platform to show that this technique can distinguish between the actin cytoskeleton organization resulting from distinct motor protein binding parameters.

scholarly journals The Long-Term Effect of Preterm Birth on Renal Function: A Meta-Analysis

2021 ◽  
Vol 18 (6) ◽  
pp. 2951
Author(s):  
Ju Sun Heo ◽  
Jiwon M. Lee
Keyword(s):  
Renal Function ◽  
Preterm Birth ◽  
Glomerular Filtration ◽  
Renal Plasma Flow ◽  
Meta Analysis ◽  
Full Term ◽  
Significant Difference ◽  
Preterm Group ◽  
Preterm Born

The preterm-born adult population is ever increasing following improved survival rates of premature births. We conducted a meta-analysis to investigate long-term effects of preterm birth on renal function in preterm-born survivors. We searched PubMed and EMBASE to identify studies that compared renal function in preterm-born survivors and full-term-born controls, published until 2 February 2019. A random effects model with standardized mean difference (SMD) was used for meta-analyses. Heterogeneity of the studies was evaluated using Higgin’s I2 statistics. Risk of bias was assessed using the Newcastle–Ottawa quality assessment scale. Of a total of 24,388 articles screened, 27 articles were finally included. Compared to full-term-born controls, glomerular filtration rate and effective renal plasma flow were significantly decreased in preterm survivors (SMD −0.54, 95% confidence interval (CI), −0.85 to −0.22, p = 0.0008; SMD −0.39, 95% CI, −0.74 to −0.04, p = 0.03, respectively). Length and volume of the kidneys were significantly decreased in the preterm group compared to the full-term controls (SMD −0.73, 95% CI, −1.04 to −0.41, p < 0.001; SMD −0.82, 95% CI, −1.05 to −0.60, p < 0.001, respectively). However, serum levels of blood urea nitrogen, creatinine, and cystatin C showed no significant difference. The urine microalbumin to creatinine ratio was significantly increased in the preterm group. Both systolic and diastolic blood pressures were also significantly elevated in the preterm group, although the plasma renin level did not differ. This meta-analysis demonstrates that preterm-born survivors may be subject to decreased glomerular filtration, increased albuminuria, decreased kidney size and volume, and hypertension even though their laboratory results may not yet deteriorate.

scholarly journals Empowering Advanced Driver-Assistance Systems from Topological Data Analysis

Mathematics ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 634
Author(s):  
Tarek Frahi ◽  
Francisco Chinesta ◽  
Antonio Falcó ◽  
Alberto Badias ◽  
Elias Cueto ◽  
...  
Keyword(s):  
Data Analysis ◽  
The State ◽  
Sensor Data ◽  
Topological Data Analysis ◽  
Motion Sensors ◽  
Driver Assistance Systems ◽  
The Road ◽  
Topological Features ◽  
Recent Developments ◽  
Topological Data

We are interested in evaluating the state of drivers to determine whether they are attentive to the road or not by using motion sensor data collected from car driving experiments. That is, our goal is to design a predictive model that can estimate the state of drivers given the data collected from motion sensors. For that purpose, we leverage recent developments in topological data analysis (TDA) to analyze and transform the data coming from sensor time series and build a machine learning model based on the topological features extracted with the TDA. We provide some experiments showing that our model proves to be accurate in the identification of the state of the user, predicting whether they are relaxed or tense.

scholarly journals Women’s demand for late-term abortion: A social or psychiatric issue?

2014 ◽  
Vol 71 (7) ◽  
pp. 660-666
Author(s):  
Gordana Nikolic ◽  
Ljiljana Samardzic ◽  
Miroslav Krstic
Keyword(s):  
Mental Health ◽  
Pregnant Women ◽  
Educational Level ◽  
Unwanted Pregnancy ◽  
Initial Assessment ◽  
Psychiatric Evaluation ◽  
Lower Socioeconomic ◽  
Significant Difference ◽  
Psychiatric Issue ◽  
Gestational Week

Introduction/Aim. Induced termination of unwanted pregnancy after 12th gestational week (late-term abortion) is legally restricted in Serbia as well as in many other countries. On the other hand, unwanted pregnancy very often brings women into the state of personal crisis. Psychiatric indications for legally approved late-term abortion on women?s demand include only severe psychiatric disorders. The aim of this paper was to compare sociodemographic, psychological characteristics and claimed reasons for abortion in the two groups of women with late-term demand for abortion - the group of women satisfying legally prescribed mental health indications, and the group of women not satisfying these indications. The aim of the study was also to determine predictive validity of the abovementioned parameters for late-term abortion as the outcome of unwanted pregnancy. Methods. A total of 62 pregnant women with demand for late-term abortion were divided into two groups according to the criteria of satisfying or not satisfying legally proposed psychiatric indications for late-term abortion after psychiatric evaluation. For the assessment of sociodemographic and psychological parameters sociodemographic questionnaire and symptom checklist - 90 revised (SCL-90?) scale were used, respectively. The outcome of unwanted pregnancy was followed 6 months after the initial assessment. Results. The obtained results showed a statistically significant difference between the groups in educational level, satisfaction with financial situation, elevated anxiety and distress reactions. Unfavorable social circumstances were the main reason for an abortion in both groups and were predictive for an abortion. A 6-month follow-up showed that women had abortion despite legal restrictions. Conclusion. Pregnant women with psychiatric indication for late-term abortion belong to lower socioeconomic and educational level group compared to women without this indication who have more frequently elevated anxiety and distress reactions to unwanted pregnancy. It is necessary to have more accurate guidelines for mental health indications for legally approved late-term abortion, respecting social circumstances. Preventive measures are of great importance in order to lower the risk of illegally performed late-term abortions.

scholarly journals Multiresolution analysis of vibration signals acquired from locomotive Diesel engine for classification of engine states basing on signal statistical parameters

2017 ◽  
Vol 168 (1) ◽  
pp. 68-72
Author(s):  
Piotr BOGUŚ ◽  
Mateusz CIESZYŃSKI ◽  
Jerzy MERKISZ
Keyword(s):  
Diesel Engine ◽  
Complex Analysis ◽  
Statistical Parameters ◽  
Vibration Signals ◽  
Time Frequency ◽  
Significant Difference ◽  
Before And After ◽  
On Line ◽  
Locomotive Diesel

The paper presents a method of classification of locomotive Diesel engine states basing on vibration signals taken from an engine body and using chosen statistical parameters calculated for the original signal and it wavelet multiresolution components. The researches presented in the paper concern estimation of an engine states before and after a general repair. The target application of the presented researches is an on-line diagnostic system which can complement standard OBD systems. To this purpose the applied methods should not base on complex analysis of some spectral, time-frequency or scalogram plots but rather on choosing single diagnostic parameters which are suitable for the fast on-line diagnostic. The results have showed the significant difference in distinguishing of engine work before and after a general repair using some chosen statistical parameters applied to vibration signals.

Vaginal examination vs. cervical length – which is superior in predicting preterm birth?

2017 ◽  
Vol 45 (8) ◽  
Author(s):  
Merav Sharvit ◽  
Reut Weiss ◽  
Yael Ganor Paz ◽  
Keren Tzadikevitch Geffen ◽  
Netanella Danielli Miller ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Medical Center ◽  
Characteristic Curve ◽  
Multiple Pregnancy ◽  
Predictive Ability ◽  
Cervical Length ◽  
Receiver Operator Characteristic Curve ◽  
Retrospective Case ◽  
Nulliparous Women ◽  
Significant Difference

AbstractObjective:To compare the predictive value of preterm birth (PTB) by transvaginal sonographic cervical length (CL) measurement to digital examination of the cervix (Bishop score – BS), in patients with premature contractions (PC) and intact membranes.Design:A retrospective case-control study.Setting:Meir Medical Center, Kfar Saba, Israel.Population:Women at 24–34 weeks of gestation who were hospitalized with PC and intact membranes.Methods:All patients underwent CL and BS measurements upon admission. Power analysis revealed that 375 patients were needed to show a significant difference between the two methods for predicting PTB. Each one served as her own control.Main outcome measures:PTB<37 and<34 weeks.Results:Receiver-operator characteristic curve (ROC) and logistic regression analyses indicated a correlation between both shortened CL and increased BS to PTB (P<0.001). Neither test offered an advantage in predicting PTB. Areas under the curve for BS and CL ROC were similar for PTB before 37 weeks gestation (0.611 vs. 0.640, P=0.28). For nulliparous women, CL predicted PTB better that BS (0.642 vs. 0.724, P=0.03). For singleton and multiple pregnancy pregnancies, BS and CL did not differ significantly in predicting PTB (P=0.9, P=0.2, respectively). For nulliparous with multiple pregnancy, the BS and CL ROC curves differ nearly significantly (0.554 vs. 0.709, P=0.07), with better predictive ability for CL.Conclusions:CL and BS have similar value in predicting PTB in patients with PC. For nulliparous women, CL is superior over the BS.

Effectiveness of cerclage for the prevention of premature birth depending on the suture material used

2020 ◽  
Vol 18 (6) ◽  
pp. 30-33
Author(s):  
O. V. YAKOVLEVA ◽  
◽  
A. G. YASHCHUK ◽  
A. V. MASLENNIKOV ◽  
A. A. TYURINA ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Suture Material ◽  
Neonatal Outcomes ◽  
Absorbable Suture ◽  
Silk Thread ◽  
Suture Materials ◽  
Significant Difference ◽  
Suture Complications ◽  
Group 2 ◽  
Duration Of Pregnancy

The purpose — to compare the effectiveness of cerclage to reduce the frequency of preterm birth when using non-absorbable suture material in the form of a braided silk thread (4 mm) and a braided tape (5 mm), as well as to identify the frequency of complications when using them. Material and methods. A retrospective analysis of cases and childbirth was conducted, as well as the analysis of own experience of applying cerclage with various suture materials in patients with isthmic-cervical insufficiency. A total of 157 patients were examined. Pregnancy outcomes, neonatal outcomes, and post-suture complications were evaluated. Results. 157 women were given cerclage at gestation periods of 14 to 23 weeks. There was no significant difference in the choice of suture material relative to the duration of pregnancy. Cerclage with thread was performed in 92 patients (58,6%) — group 1 and 65 patients were sutured with tape (41,4%) — group 2. Preterm birth occurred in 28 patients of the 2nd comparison group (18%) and 45 patients of the 1st group (29%). The duration of pregnancy in preterm birth was comparable in both groups. Conclusions. The study found that preterm birth after cerclage using a braided tape occurred less frequently than with the use of a braided silk thread. There were no significant differences in neonatal outcomes in the comparison groups. Complications after cerclage, such as suture and cervical rupture, were found only in the group of women who underwent surgery using a woven silk thread.

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