Sleep quality and its effect on event related potential P300 in adolescents with and without sleep disturbances

Author(s):  
Anam Aseem ◽  
Mohammed Ejaz Hussain

Abstract Objectives The present study aimed: (i) to investigate the sleep quality and cortical arousal (ERP P300) in adolescents with and without sleep disturbances, and (ii) to examine whether P300 vary as a function of quality of the previous night’s sleep in sleep disturbed adolescents and to compare the findings with healthy controls. Methods Fifteen sleep disturbed adolescents and 15 age-matched controls were recruited. Participants filled 10 days of sleep logs to identify their good (GN) and bad nights (BN). GN and BN were scored as a measure of sleep efficiency (SE), with nights having greater SE defined as GN and nights with lower SE scores labelled as BN. Afterwards, subjects were summoned to the lab for recording ERP P300 once after a night of good sleep (GN) and once after a night of bad sleep (BN). Results The findings demonstrate that sleep disturbed adolescents exhibited poorer quality of sleep than controls. The ERP P300 also revealed significant difference in participants with and without sleep disturbance. Moreover, the P300 amplitude was higher and the latency was shorter after a GN in sleep disturbed as well as in controls, however, the values were better for adolescents without disturbed sleep. Similarly, amplitude and latency of P300 was lower and longer, respectively, after a BN in both the groups, however, participants with sleep disturbance demonstrated very penurious scores for amplitude and latency than the controls. Conclusion Adolescents with sleep disturbance have poorer sleep quality and ERP characteristics than their healthy counterparts. Moreover, the quality of the previous night sleep determines cortical arousal in both sleep disturbed and healthy controls.

2017 ◽  
Vol 4 (07) ◽  
pp. 1463 ◽  
Author(s):  
Azadeh Memarian ◽  
Afsaneh Sanatkaran ◽  
Seyyed Mohialdin Bahari

Background: The aim of the present study is to evaluate the effects of laughter yoga exercises on anxiety and sleep quality in patients suffering from Parkinson’s disease. Methods: In the study a semi-empirical and applied research design was used, which involved a pre-test and post-test, and appropriate control group. The study consisted of 24 patients suffering from Parkinson’s disease who were referred and admitted to Hazarate Raoul Allah Hospital in Tehran, Iran. The patients ranged in age from 55 to 75 and met the study criteria prior to entering the research study. The patients were randomly divided into two groups – control or experimental (n=12 per group). After completing exercises (laughter yoga), post-evaluation of anxiety and sleep quality of patients in both groups were conducted using questionnaires. For normalization of research data, the Mann-Whitney nonparametric test was used. Statistical analyses were conducted using the SPSS software, with the statistically significant level set at P<0.05. Results: The Mann-Whitney tests indicated that there was a significant difference between the  average stress change as well as sleep quality in patients suffering from Parkinson’s disease (versus control subjects) following laughter yoga exercises. Indeed, regarding sleep quality laughter yoga was only effective on the subjective quality of sleep and latency in sleeping. There was no observation of a significant effect on the duration of sleep, sleep efficiency, sleep disturbances, use of sleeping pills, or daily functions of the patients. Conclusion: The results of the present study demonstrate that laughter yoga exercises can reduce anxiety and improve sleep quality in patients suffering from Parkinson’s disease. As a result, laughter yoga exercises may be beneficial as a complementary therapy with standard treatment methods to reduce anxiety and improve sleep quality in patients with Parkinson's.  


2021 ◽  
Vol 5 (1) ◽  
pp. 42
Author(s):  
Shinta Wurdiana Rhomadona ◽  
Dianita Primihastuti

As gestational age increases, the quality of sleep can decrease. It was reported that about 60% of late trimester pregnant women experience fatigue and> 75% experience sleep disturbances. However, these complaints are often ignored, even though it can lead to an increased risk of gestational hypertension, diabetes, prematurity, and postpartum depression. Sleep disturbances can also cause depression and stress that affects the fetus. Mild stress causes an increase in fetal heart rate which, if left untreated, will make the baby hyperactive. Meanwhile, the consequences are depression and babies who are born have less time to sleep deeply. Efforts to overcome this sleep disorder are yoga and lavender aromatherapy inhalation. Purpose: Therefore, the researchers estimated that the application of a combination of prenatal gentle yoga and lavender aromatherapy would be more effective in affecting the quality of sleep in pregnant women, so it is hoped that it can reduce sleep disturbances in third trimester pregnant women. Results: There is a significant effect of the combination of prenatal gentle yoga and inhalation of lavender aromatherapy in improving sleep quality in the treatment group with a value of α = 0.011 or α <0.05. There was a significant difference in the quality of sleep in the group compared to the control group with a value of α = 0.004 or α <0.05. Conclusion: By practicing prenatal gentle yoga and regular inhalation of lavender aromatherapy, it will be able to improve sleep patterns without using sleeping pills which wil


JKEP ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 69-85
Author(s):  
Yupi Supartini ◽  
Puput Dwi Martiana ◽  
Titi Sulastri

Excessive smartphone use has a higher risk of sleep disturbances and affects a person’s sleep quality.  The purpose of this research is to determine the relationship between respondent’s characteristics and smartphone addiction to the sleep quality of adolescents at Budi Cendikia Islamic School Depok.  This type of research is quantitative with a descriptive analytic approach and a cross sectional research design.  The population is all 359 students.  Sampling in this study using stratified random sampling technique with 112 respondents.  The SAS-SV questionnaire was used to measure the level of smartphone addiction, while the PSQI questionnaire was used to measure sleep quality in adolescents.  The statistical test used Chi Square and Mann Whitney with a significance level of α = 0.05.  The results of the univariate statistical test showed that most of the respondents were male (52.7%), 13 years old (35.7%), had a high rate of smartphone addiction (61.6%), and poor sleep quality (70.5%).  Meanwhile, the results of the bivariate statistical test showed that there was a significant difference between gender (p = 0.020) and smartphone addiction (p = 0.007) with sleep quality, but there was no significant difference between age and sleep quality (p = 0.938). This study concludes that there is a relationship between gender and smartphone addiction on students' sleep quality, but there is no relationship between age and sleep quality of students.  Hence, it is necessary to limit the use of smartphones so that smartphone addiction can be minimized and sleep quality is good.”


2013 ◽  
Vol 44 (10) ◽  
pp. 2151-2162 ◽  
Author(s):  
K. C. Chen ◽  
I. H. Lee ◽  
Y. K. Yang ◽  
S. Landau ◽  
W. H. Chang ◽  
...  

BackgroundReduced P300 event-related potential (ERP) amplitude and latency prolongation have been reported in patients with schizophrenia compared to healthy controls. However, the influence of antipsychotics (and dopamine) on ERP measures are poorly understood and medication confounding remains a possibility.MethodWe explored ERP differences between 36 drug-naive patients with schizophrenia and 138 healthy controls and examined whether P300 performance was related to dopamine transporter (DAT) availability, both without the confounding effects of medication. We also conducted a random effects meta-analysis of the available literature, synthesizing the results of three comparable published articles and our local study.ResultsNo overall significant difference was found in mean P300 ERP between patients and controls in latency or in amplitude. There was a significant gender effect, with females showing greater P300 amplitude than males. A difference between patients and controls in P300 latency was evident with ageing, with latency increasing faster in patients. No effect of DAT availability on P300 latency or amplitude was detected. The meta-analysis computed the latency pooled standardized effect size (PSES; Cohen's d) of −0.13 and the amplitude PSES (Cohen's d) of 0.48, with patients showing a significant reduction in amplitude.ConclusionsOur findings suggest the P300 ERP is not altered in the early stages of schizophrenia before medication is introduced, and the DAT availability does not influence the P300 ERP amplitude or latency. P300 ERP amplitude reduction could be an indicator of the progression of illness and chronicity.


2018 ◽  
Vol 6 (12) ◽  
pp. 2342-2347
Author(s):  
Mohammad Zaman Kamkar ◽  
Sommayeh Rezvani Khorshidi ◽  
Seideh Mahrokh Alinaghi Maddah ◽  
Amir Emami Zeydi ◽  
Mahnaz Modanloo

BACKGROUND: Quality of sleep, as a basic need, is an important factor for surviving patients in hospitals. Many factors may contribute to disturbing patients sleep, such as continuous ambient light, is required for healthcare providers to monitor patients. Ambient light can influence patients' quality of sleep due to melatonin secretion. AIM: Study aimed to determine the correlation between nocturnal melatonin levels and sleep quality in patients admitted to the Cardiac Care Units (CCU). MATERIAL AND METHODS: This cross-sectional study was done on inpatients of CCUs at Amir-Almomenin Hospital in Kordkoy city, a cardiac referral hospital in the northeastern of Iran in 2015. Sixty-eight inpatients were selected through convenience sampling. Before data gathering light level of CCUs was measured every one hour in 2 days, the quality of nocturnal sleep was investigated through Verran and Snyder-Halpern (VSH) Sleep Scale at the second night of admission urinary melatonin level was measured at the same night in all urine excreted between 22:00 pm and 07:00 am. RESULTS: The mean and standard deviation (SD) score of sleep quality in three dimensions of sleep disturbance, sleep effectiveness and sleep supplementation were 336.6 ± 149.9, 269.0 ± 82.2, and 175.2 ± 30.7, respectively. Also, the mean and SD of nocturnal urinary melatonin levels was 323.02 ± 136.21 pg/ml. There was not a significant correlation between level of nocturnal melatonin and three domains of sleep quality; sleep disturbance (r = 0.005, P = 0.968), sleep effectiveness (r = 0.090, P = 0.464), and sleep supplementation (r = -0.037, P = 0.763). CONCLUSION: According to the result, most CCUs patients suffer from sleep disturbance. However, there was no correlation between the level of melatonin and sleep quality. There is a need for recognising the reasons for sleep disturbances in Cardiac Care Units. It is imperative for care providers to be able to recognise the causes of sleep disturbances and to modify environmental factors such as ambient light to improve sleep quality in hospitalised patients.


Author(s):  
Neenu Merin ◽  
Regina Antony

Objective: This was a descriptive study with the objective to determine the sleep disturbances and the quality of sleep among patients with cardiovascular diseases (CVDs).Methods: Quantitative approach with non-experimental descriptive design was used. A semi-structured sleep disturbance questionnaire was used to determine the sleep disturbances, and a standardized Pittsburgh Sleep Quality Index tool was used to assess the sleep quality among 100 subjects in Amrita Institute of Medical Sciences, Kochi.Results: The study results showed that majority of the subjects (51%) were of the age group between 56 and 65 years, and 71% were male with CVD. Sleep disturbances were present in 80% of the subjects with CVD, among which 56% subjects had mild disturbances, 20% subjects with moderate sleep disturbances, and 4% subjects with severe sleep disturbances. The result also indicated that 48% of subjects had poor sleep quality. Findings also showed a highly statistically significant association between cardiomyopathy and sleep disturbances (p<0.001). Total cholesterol and low-density cholesterol levels were significantly associated with sleep disturbances (p<0.05). There is a highly significant association between sleep disturbances and quality of sleep (p<0.001), indicating that sleep disturbances can be one factor in decreasing the quality of sleep in patients with CVD.Conclusion: The results of the study indicated that sleep disturbances were prevalent in patients with CVD and often hazardous to heart health. As health practitioner and other health-care providers have not focused major attention on the importance of sleep to health, the need for providing information to them and patients regarding the importance of improving the quality of sleep and identifying the sleep disturbances will call for action to bring sleep to the forefront of public health.


2020 ◽  
Vol 22 (Supplement_2) ◽  
pp. ii181-ii181
Author(s):  
Pin-Yuan Chen ◽  
Hsiao-Yean Chiu ◽  
Pei-Ching Lin

Abstract BACKGROUND Sleep disturbances are common complaints in adult brain tumor patients and impact their quality of life profoundly. The prevalence and pattern of preoperative sleep disturbances are still unknown. MATERIAL AND METHOD There were 36 adult patients with primary brain tumors who were recruited before craniotomy. All participants completed a battery of questionnaires, including the Athens Insomnia Scale, Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index, Brief Fatigue Inventory, Hospital Anxiety, and Depression Scale, Morningness-Eveningness Questionnaire, and EORTC-QLQ-BN20. Actigraphy was put on a non-dominant wrist for obtaining objective sleep parameters, such as the dichotomy index. RESULT The prevalence of preoperative insomnia, poor sleep quality, excessive daytimes sleepiness, and circadian disruption were all high but similar between benign and malignant brain tumor groups. Patients with glioma had poorer quality of life. Insomnia was the only sleep disturbance that significantly associated with quality of life in a multivariate linear regression modal. CONCLUSION Sleep disturbances are common in adult brain tumor patients. Insomnia worse the quality of life of these patients. A further longitudinal investigation of sleep disturbances and quality of life in brain tumor patients is worthful.


Author(s):  
Neenu Merin ◽  
Regina Antony

Objective: This was a descriptive study with the objective to determine the sleep disturbances and the quality of sleep among patients with cardiovascular diseases (CVDs).Methods: Quantitative approach with non-experimental descriptive design was used. A semi-structured sleep disturbance questionnaire was used to determine the sleep disturbances, and a standardized Pittsburgh Sleep Quality Index tool was used to assess the sleep quality among 100 subjects in Amrita Institute of Medical Sciences, Kochi.Results: The study results showed that majority of the subjects (51%) were of the age group between 56 and 65 years, and 71% were male with CVD. Sleep disturbances were present in 80% of the subjects with CVD, among which 56% subjects had mild disturbances, 20% subjects with moderate sleep disturbances, and 4% subjects with severe sleep disturbances. The result also indicated that 48% of subjects had poor sleep quality. Findings also showed a highly statistically significant association between cardiomyopathy and sleep disturbances (p<0.001). Total cholesterol and low-density cholesterol levels were significantly associated with sleep disturbances (p<0.05). There is a highly significant association between sleep disturbances and quality of sleep (p<0.001), indicating that sleep disturbances can be one factor in decreasing the quality of sleep in patients with CVD.Conclusion: The results of the study indicated that sleep disturbances were prevalent in patients with CVD and often hazardous to heart health. As health practitioner and other health-care providers have not focused major attention on the importance of sleep to health, the need for providing information to them and patients regarding the importance of improving the quality of sleep and identifying the sleep disturbances will call for action to bring sleep to the forefront of public health.


2021 ◽  
Vol 10 (6) ◽  
pp. 3819-3822
Author(s):  
Nikita H. Seth

Human health has suffered a lot as a result of changing times and technological advances. Poor sleep quality affects people of all ages, non- pharmacological solution is increasingly becoming a requirement. Exercises in the brain gym are a good contender in the competition. However, there is still more work to be done before a definitive conclusion can be made about its effectiveness as a intervention. This study aims to evaluate the sleep disturbance and effect of brain gym exercises in improving sleep in the undergraduate physiotherapy students. Here’s idea we suggest to evaluate the sleep disturbance and effect of brain gym exercises as an intervention with duration of practice as 5 days in a week with a section of 25 minutes which is completed in one hour. Insomnia Rating scale is used to get the desired population for giving the intervention and Pittsburgh Sleep Quality Index (PSQI), which has 86.5% specificity and 89.6% sensitivity. The duration of study will be six months. The study design is pre and post interventional study. In this Hypothesis we aim to assess the efficacy of brain gym exercises for improving quality of sleep and treating mild to moderate insomnia. Brain gym exercises are already proved to improve the attention, memory, cognition and provide relaxation. The expected outcome includes detection of sleep disturbances and improvement in sleep quality which will be evaluated using PSQI. Data analysis will be done using students paired t test and conclusion of the study will be published after the results are analyzed.


Medicina ◽  
2010 ◽  
Vol 46 (7) ◽  
pp. 482 ◽  
Author(s):  
Evelina Preišegolavičiūtė ◽  
Darius Leskauskas ◽  
Virginija Adomaitienė

The objective of the study was to analyze associations among quality of sleep, profile of the studies, and lifestyle factors among the students of three different study profiles (medicine, economics, and law). Material and methods. A total of 405 randomly selected students from the first and fourth years of studies from 4 different universities in Lithuania answered the standardized questionnaires consisting of two parts: 1) the Pittsburgh Sleep Quality Index (PSQI) for subjective evaluation of sleep quality; 2) the questionnaire about sleep and lifestyle habits and impact of poor sleep on the quality of life developed by the researchers. Results. More than half (59.4%) of the students scored higher than 5 on the PSQI, which allowed suspecting sleep disorders. A significant difference in the frequency of poor sleepers was found regarding the profile of studies (P<0.05) showing the highest frequency of sleep disturbances among medical students. There was a significant correlation between quality of sleep and subjective evaluation of quality of life (P<0.01). Medical students experienced the highest impact of poor sleep on the quality of life (P=0.008). Students studying before going to sleep, spending more time studying, and having less leisure time had worse quality of sleep (P<0.01). A significant difference was found among three profiles of studies regarding the anxiety about studies (P<0.0005) and subjective estimation of success in studies (χ²=27.9, P<0.0005), showing the highest anxiety and worst satisfaction among students of medicine. Conclusions. The incidence of sleep problems is high among students in Lithuania, reaching 59.4%. Medical students have worse quality of sleep and worse impact of poor sleep on the quality of life compared to students of law and economics. A significant difference was found between medical students and their peers in other profiles of studies regarding their attitudes and habits related to studies: medical students spent more time for studying, were more anxious about studies and less satisfied with the results, studied more often before going to sleep.


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