scholarly journals Malignant perivascular epitheloid cell tumour (PEComa) of the lung – a rare entity

2017 ◽  
Vol 2 (1) ◽  
pp. 39-42
Author(s):  
Amitabha Chakrabarti ◽  
Manujesh Bandyopadhyay ◽  
Biswarup Purkayastha

AbstractMalignant Perivascular Epitheloid Cell Tumour (PEComa) of the lung is very rare, with only six cases reported in literature. This case presented with a large mass originating from right upper lobe of the lung with dilemma in its histopathological diagnosis and management. Postoperative histopathology after a right upper and middle lobectomy describes a tumour with an alveolar/nested pattern of growth and epitheloid morphology with expression of TFE-3 and diagnosed as PEComa. After 6 months the patient had a local recurrence inside the thorax & chest wall.This case qualifies it as a rare type of malignant PEComa with younger age of presentation, aggressive clinical behaviour & malignant histological features along with TFE3 positivity on immunohistochemistry. This case is probably the first of its kind with the largest reported size involving two lobes of the lung.

2020 ◽  
Vol 2 ◽  
pp. 73-76
Author(s):  
Birma Ram ◽  
Pankaj Sharma ◽  
Manoj Gopinath ◽  
Shamresh Kumar Singh

Extraskeletal osteosarcoma is a rare malignant mesenchymal tumor which typically affects elderly patients and the commonly affected sites are extremities, retroperitoneum, mesentery, and trunk. Extraskeletal osteosarcoma arising from colon or retroperitoneum can manifest as a large mass with features of intestinal or urinary tract obstruction. Local recurrence after excision and distant metastasis are common, so regular follow-up and surveillance of such patients are advisable after excision of the primary tumor.


HPB Surgery ◽  
1996 ◽  
Vol 10 (1) ◽  
pp. 55-57 ◽  
Author(s):  
José I. Rodríguez García ◽  
Juan. J. González González ◽  
Luis J. García Flórez ◽  
Paloma Floriano Rodríguez ◽  
Enrique Martínez Rodríguez

A case of metastatic granulosa cell tumour of the ovary is reported. Investigations revealed a secondary tumour in segment VI and VII of the liver. Right hepatic resection was performed. Microscopic findings revealed a tumour with histological features identical to that removed eleven years before.


2018 ◽  
Vol 26 (8) ◽  
pp. 749-757 ◽  
Author(s):  
Anupma Nayak ◽  
Ira J. Bleiweiss ◽  
Kimberly Dumoff ◽  
Tawfiqul A. Bhuiya

Primary mucinous cystadenocarcinoma (MCA) of breast is an exceedingly rare tumor with histologic resemblance to MCA arising in ovary, pancreas, and gastrointestinal tract. In this article, we present 2 additional cases of MCA of breast, one highlighting the diagnostic challenges of a rare entity that may potentially lead to unnecessary chemotherapy and the second case presenting with recurrence after 8 years of primary surgical excision defying the indolent behavior reported in the literature. To our knowledge, this is the first reported instance of such behavior.


2016 ◽  
Vol 10 (5-6) ◽  
pp. 201
Author(s):  
Lei Chen ◽  
Lu Fang ◽  
Zhiqi Liu ◽  
Dexin Yu ◽  
Daming Wang ◽  
...  

Adrenal germ cell tumour is very rare. We report a case of a 59-year-old woman who presented with right flank discomfort. The laboratory examinations were normal and the chest computed tomography (CT) showed right pleural effusion. The abdominal CT scan revealed a large mass on the right adrenal gland. The patient underwent an adrenalectomy. Histopathologic examination and immunohistochemical findings were consistent with mixed germ cell tumour. Three months later following the operation, the patient was admitted to our hospital again with chest tightness and shortness of breath. The chest CT showed right pleural effusion recurrence and enlargement of mediastinal lymph nodes and right hilar lymph nodes. The patient had right supraclavicular lymphadenectasis on physical examination. Fine needle aspiration cytology from the supraclavicular lymph nodes showed groups of malignant tumour cells. The patient died within 6 months postoperatively. In this case, the lymph node pathway played an important role in the metastatic procedure.


2019 ◽  
Vol 12 (3) ◽  
pp. e227510
Author(s):  
Cláudia Santos ◽  
Ana Virgínia Araújo ◽  
Helena Contente ◽  
Cláudia Branco

Granular cell tumours are rare neoplasms that may occur anywhere in the body. The most common locations are the oral cavity, skin and subcutaneous tissue, with only 8% of these tumours occurring at a gastrointestinal site. In the specific case of gastric granular cell tumours, only a few cases have been published until today. Granular cell tumours are usually benign; however, some malignant forms have been reported. Both endoscopic and surgical resection represent the treatment of choice. The authors report a new clinical case of a gastric granular cell tumour, treated with laparoscopic surgical resection, describing some endoscopic, imagiological and anatomopathological features.


2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
Hiromasa Arai ◽  
Yasushi Rino ◽  
Teppei Nishii ◽  
Norio Yukawa ◽  
Nobuyuki Wada ◽  
...  

Extraskeletal osteosarcoma is an uncommon high-grade malignant soft tissue sarcoma. Well-differentiated extraskeletal osteosarcoma is thought to have a better prognosis than classical extraskeletal osteosarcoma, but dedifferentiation after recurrence has also been reported. We present a case of a primary retroperitoneal extraskeletal osteosarcoma in a 62-year-old Japanese woman. Abdominal CT revealed a large mass with diffuse calcification in the right retroperitoneal space and tumor resection was performed. The histopathological diagnosis was well-differentiated retroperitoneal extraskeletal osteosarcoma. She was followed up by CT every 6 months without adjuvant radiotherapy and chemotherapy for 31 months until anaplastic high-grade spindle cell sarcoma recurred in the retroperitoneum. Our case is the seventh reported description of well-differentiated extraskeletal sarcoma, and the first to arise in the retroperitoneum and recur as an entirely dedifferentiated spindle cell sarcoma.


2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
M Abid ◽  
R Bano ◽  
M Salim ◽  
A I Khan ◽  
M Z Chaudhry ◽  
...  

Abstract Background Breast cancer diagnosed at younger age has aggressive biology being triple negative and high grade and associated with poor prognosis. Method Retrospectively data of 121 patients age 30 years or younger registered during the year 2008 was reviewed. Demographics studied were age at diagnosis, gender, pregnancy, or lactation associated, family history, histopathological diagnosis, stage of the disease, receptors, type of treatment, response, local recurrence, distant relapse, survival. Results One patient was male. Age range 20 -30 years, single patient had bilateral involvement. half 50.4%(n = 61) patients had locally advanced disease at presentation. Pregnancy/ lactation associated breast cancer was seen in 29.8%(n = 36). Most common stage was stage III (52.1%) & stage II (33.9%). IDC was the most common histology 94.2% (n = 114) Triple negative was most common molecular subtype present in 46.3%(56). After 5 years follow up, local recurrence was observed in 12.4%(n = 15), cancer related deaths were 42.1%(n = 51). Conclusions Breast cancer in very young has very aggressive tumor biology, needs aggressive treatment with surgery, chemotherapy, radiation therapy and hormonal therapy, furthermore there is need to identify possible environmental factors which may contribute in the rising incidence in this age group.


2003 ◽  
Vol 5 (4) ◽  
pp. 241-244 ◽  
Author(s):  
S Lester ◽  
K Pratschke

A 2-year old, neutered male domestic short hair cat presented with a large mass involving the right upper lip and underlying gingiva. A previous attempt at mass excision had failed, and the histopathological diagnosis was reported to be a fibrosarcoma. The cat was otherwise in good health. A central hemimaxillectomy was performed with extensive soft-tissue dissection and maxillofacial reconstruction achieved using an axial pattern flap based on the superficial temporal artery. This is the first reported clinical case of the use of the superficial temporal artery axial pattern flap in the cat. Histopathology identified a periodontal fibromatous epulis.


Sign in / Sign up

Export Citation Format

Share Document