scholarly journals Pathophysiology and classification of pseudomyxoma peritonei

2016 ◽  
Vol 1 (1) ◽  
pp. 3-13 ◽  
Author(s):  
Mark Bignell ◽  
Norman J. Carr ◽  
Faheez Mohamed

AbstractBackground: The term pseudomyxoma peritonei (PMP) was first described in 1884 and there has been much debate since then over the term. A recent consensus of world experts agreed that PMP should be thought of as a clinical entity characterised by the presence of mucinous ascites, omental cake, peritoneal implants and possibly ovarian involvement. It generally originates from mucinous appendiceal tumours.Content: This review details the clinical presentation of this unusual condition, presents the new classification system and how this relates to outcome. The pathophysiology of this disease is also explored with a special reference to the relationship of the disease to tumour markers.Summary: A classification system has been agreed upon by the leading experts in PMP which is now divided into low and high grade mucinous carcinomatosis peritonei. This distinction correlates with clinical outcome as does the presence of raised tumour markers preoperatively.Outlook: Research needs to be focused on understanding the factors associated with poor prognosis through well designed multi-centred prospective studies. This will allow us to identify patients with bad tumour biology so that targeted treatment based on likely prognosis may then become a reality.

1983 ◽  
Vol 63 (1) ◽  
pp. 97-112
Author(s):  
M. W. SONDHEIM ◽  
K. KLINKA

The ability of a phytosociologically based, ecological classification system to explain the variability of soil and physiographic properties is tested. Sixty stands from a research forest in southwestern British Columbia are defined in terms of three categorical levels of the ecosystem taxonomy of V. J. Krajina. The stands belong to 14 associations, eight alliances, and three orders. Using these taxa, nested and one-way analyses of variance are performed on 40 soil and physiographic properties of the included ecosystems. Because the hierarchy tested is unbalanced and the samples are of unequal size, the estimates and significance of the variance components for both analyses are determined by approximation techniques. The results from the one-way analyses show that for mineral soil pH and for most physiographic factors between one-half and two-thirds of the variability can be explained by the classification of the ecosystems into associations. For the other properties and for the alliances and orders, this proportion is typically much lower. The study suggests that for general pedologic and environmental characterization there may be little justification for using the alliance and order categories. Key words: Soil-plant relationships, taxonomy, biogeocoenose, integrated classification


2013 ◽  
Vol 726-731 ◽  
pp. 1566-1572 ◽  
Author(s):  
Shi Qiang Ding ◽  
Qing Na Li ◽  
Xin Rong Pang ◽  
Ji Run Xu

The characteristics of flocs aggregated in flocculation have been paid more and more attention for a long time. In this paper, a new classification and analyses method dealing with the flocs is developed. The flocs formed after flocculation is divided into four kinds, including the left primary particles, linear flocs with all component particles in a line, planar flocs with all component particles on a plane and volumetric flocs with all component particles in a three-dimensional space. By analyzing the formation approaches of different kind of flocs regardless of the floc breakage, the number of every kind of floc is analyzed to be related with the suspension concentration mathematically. After comparing the different items in the models describing the relationship of floc number and concentration, a series of simplified expressions are presented. Lastly, a mathematical equation relating the measurable suspension viscosity with the numbers of different flocs is obtained.


PEDIATRICS ◽  
1982 ◽  
Vol 69 (5) ◽  
pp. 537-543
Author(s):  
Marie C. McCormick ◽  
Sam Shapiro ◽  
Barbara Starfield

A mother's expectations about the development of her infant have been found to be a strong determinant of child development, but little is known about the factors that may affect maternal assessment of development. In this study, the relationship of the mother's opinion of the development of her infant with several sociodemographic, antenatal, intrapartum, and infant health variables was examined for a large sample of 1-year-old infants for whom gross motor observations were also obtained at the time of the interview. Among those observed to be developing at an appropriate rate, 4.0% were perceived by their mothers as developing more slowly than the mothers considered normal; among infants developing more slowly, 28.6% were considered to be developing slowly by their mothers. In both groups, the major determinants of maternal opinion of slow development concerned the infant's health: low birth weight, congenital anomalies regardless of severity, hospitalization during the first year of life, and high ambulatory care use. These results indicate that maternal perception of infant development may not reflect the infant's level, but past or present illness, and raise questions about the influence of infant health on maternal-infant interactions and the effect of such interactions on subsequent development in the child.


1967 ◽  
Vol 54 (4) ◽  
pp. 609-617 ◽  
Author(s):  
R. G. Milet ◽  
E. R. Plunkett ◽  
D. H. Carr

ABSTRACT The authors report a female patient with XXi constitution for the long arm of the X chromosome associated with thyroid abnormalities, high digital ridge count and chronic suppurative otitis media. This is followed by a discussion of the correlation between genotype and phenotype, comment on the Lyon hypothesis, the relationship of thyroid abnormalities to this condition, autoimmune disease, unbalanced sex chromosomal constitution and the association with a high total digital ridge count. Finally a single hypothesis is proposed for the associated clinical entities that have been found and the suggestion that the classification of this particular type of gonadal dysgenesis be considered as a new syndrome, the »XX-isochromosome syndrome«.


PEDIATRICS ◽  
1957 ◽  
Vol 19 (6) ◽  
pp. 1109-1123
Author(s):  
M. A. Ogryzlo ◽  
H. A. Smythe

Attention is drawn to the difficulties that may be encountered in the positive identification and classification of many patients suspected of suffering from systemic lupus erythematosus. Much of this is due to a lack of specific criteria, either clinical or pathologic, for the diagnosis of the disease. The problem has been made more difficult by the recognition of a number of other syndromes that bear a superficial resemblance to systemic lupus erythematosus, yet differ in clinical manifestations, natural course, prognosis and other respects. A feature common to the group is the presence of the L.E. cell phenomenon. The related conditions differ from lupus enythematosus in that the L.E. phenomenon may only be demonstrable intermittently especially during severe exacerbations of the disease, while at the same time disturbances in the electrophoretic pattern of the serum proteins may be much more profound. In systemic rheumatoid disease the prognosis without steroid therapy is better than in systemic lupus erythematosus, although the morbidity may be great. The reactions which follow administration of certain chemotherapeutic agents are of considerable interest, particularly in view of the similarity to lupus erythematosus and rheumatoid arthritis, and the reversibility on withdrawal of the offending agent. The relationship of these syndromes to each other and to classical systemic lupus erythematosus has not yet been resolved, and inclusion of them under the diagnosis of systemic lupus erythematosus at this time must be regarded as premature.


Author(s):  
Vera Savchenko ◽  
◽  
Oleksandr Gai ◽  
Oksana Yurchenko ◽  
◽  
...  

The article considers the essence of accounting theories, approaches to their separation, the relationship of accounting and economic theories, and the direction of development of accounting theories in accordance with the needs of economic and social development. The approaches to the classification of accounting theories are generalized, as well as the approaches to the interpretation of «accounting theory», the peculiarities of the interpretation of the subject of accounting from the point of view of different accounting theories are revealed and the objectivity of expansion of accounting objects is substantiated. In the context of the formation and development of accounting theories, the category of «social costs» is considered as an accounting object.


Entropy ◽  
2019 ◽  
Vol 21 (2) ◽  
pp. 141 ◽  
Author(s):  
Gregg Jaeger

The question of whether virtual quantum particles exist is considered here in light of previous critical analysis and under the assumption that there are particles in the world as described by quantum field theory. The relationship of the classification of particles to quantum-field-theoretic calculations and the diagrammatic aids that are often used in them is clarified. It is pointed out that the distinction between virtual particles and others and, therefore, judgments regarding their reality have been made on basis of these methods rather than on their physical characteristics. As such, it has obscured the question of their existence. It is here argued that the most influential arguments against the existence of virtual particles but not other particles fail because they either are arguments against the existence of particles in general rather than virtual particles per se, or are dependent on the imposition of classical intuitions on quantum systems, or are simply beside the point. Several reasons are then provided for considering virtual particles real, such as their descriptive, explanatory, and predictive value, and a clearer characterization of virtuality—one in terms of intermediate states—that also applies beyond perturbation theory is provided. It is also pointed out that in the role of force mediators, they serve to preclude action-at-a-distance between interacting particles. For these reasons, it is concluded that virtual particles are as real as other quantum particles.


1972 ◽  
Vol 104 (7) ◽  
pp. 1055-1071 ◽  
Author(s):  
Akira Mutuura

AbstractIn the phylogenetic classification of the Lepidoptera, the position of the genital opening and its modifications help to clarify the relationship of the Zeugloptera to the lepidopterous suborders. Three different systems of the suborder classification of the Lepidoptera, into Homoneura and Heteroneura (Tillyard, Imms, etc.), Monotrysia and Ditrysia (Borner), and Dacnonypha, Monotrysia, and Ditrysia (Hinton), are not supported by evidence obtained in the study of the female genitalia.The development of the female terminalia is closely associated with the mode of oviposition. Several types of female terminalia are found in the primitive Lepidoptera (Hepialidae, Neopseustidae, Tischeriidae, Lyonetiidae, Agathiphagidae, Tineidae, Nepticulidae, and Eriocraniidae). They are divided into four categories: hepialid type — the eggs are dropped randomly; typical lepidopterous type — the eggs are laid on the surface of food plants; eriocraniid type — the eggs are laid inside the food plants; tineid type — the eggs are laid in crevices of food. Each of the types is derivable from the types occurring in Neopseustidae, Tischeriidae, Agathiphagidae, and Eriocraniidae, respectively. These types are still far removed from the type of female terminalia in Micropterygidae of the Zeugloptera.The modes of egg-laying as well as the morphological characters of the female genitalia must be taken into consideration in suborder classification of the Lepidoptera.A genealogical tree based on the female terminalia suggests four main branches: hepialid branch — includes Neopseustidae and Prototheoridae; typical lepidopterous branch — includes all Ditrysia and Nepticulidae; tineid branch — includes only Tineidae; eriocraniid branch — includes Incurvariidae, Prodoxidae, Adelidae, and Heliozelidae.


2018 ◽  
Vol 48 (1) ◽  
pp. 125-148 ◽  
Author(s):  
David Andrew Griffiths

The 2006 ‘Consensus statement on management of intersex disorders’ recommended moving to a new classification of intersex variations, framed in terms of ‘disorders of sex development’ or DSD. Part of the rationale for this change was to move away from associations with gender, and to increase clarity by grounding the classification system in genetics. While the medical community has largely accepted the move, some individuals from intersex activist communities have condemned it. In addition, people both inside and outside the medical community have disagreed about what should be covered by the classification system, in particular whether sex chromosome variations and the related diagnoses of Turner and Klinefelter’s syndromes should be included. This article explores initial descriptions of Turner and Klinefelter’s syndromes and their subsequent inclusion in intersex classifications, which were increasingly grounded in scientific understandings of sex chromosomes that emerged in the 1950s. The article questions the current drive to stabilize and ‘sort out’ intersex classifications through a grounding in genetics. Alternative social and historical definitions of intersex – such as those proposed by the intersex activists – have the potential to do more justice to the lived experience of those affected by such classifications and their consequences.


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