The First Occurrence in Nature of Two Compounds from Hops

2003 ◽  
Vol 58 (9-10) ◽  
pp. 640-642 ◽  
Author(s):  
Yan Qu ◽  
Zhi-Hui Ding ◽  
Ji-Kai Liu
Keyword(s):  
Natural Products ◽  
Humulus Lupulus ◽  
Spectral Evidence ◽  
First Occurrence ◽  
First Time

AbstractTwo compounds, (p-methoxyphenyl) diphenylmethanol (1) and tribenzylamine (2), were isolated from Humulus lupulus. Their structures were established on the basis of spectral evidence (MS, IR, NMR, HMBC, HMQC, 1H-1H COSY experiments). Compounds 1 and 2 were found as natural products at the first time.

scholarly journals Antiproliferative Effects of Alkaloid Evodiamine and Its Derivatives

2018 ◽  
Vol 19 (11) ◽  
pp. 3403 ◽  
Author(s):  
Xu Hu ◽  
Dahong Li ◽  
Chun Chu ◽  
Xu Li ◽  
Xianhua Wang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Natural Products ◽  
Drug Administration ◽  
Antiproliferative Activity ◽  
Natural Source ◽  
Antiproliferative Effects ◽  
Anti Cancer ◽  
Ring Structures ◽  
First Time ◽  
Antiproliferative Activities

Alkaloids, a category of natural products with ring structures and nitrogen atoms, include most U.S. Food and Drug Administration approved plant derived anti-cancer agents. Evodiamine is an alkaloid with attractive multitargeting antiproliferative activity. Its high content in the natural source ensures its adequate supply on the market and guarantees further medicinal study. To the best of our knowledge, there is no systematic review about the antiproliferative effects of evodiamine derivatives. Therefore, in this article the review of the antiproliferative activities of evodiamine will be updated. More importantly, the antiproliferative activities of structurally modified new analogues of evodiamine will be summarized for the first time.

The sequence and correlation of Early Ordovician (Arenig) graptolite faunas in the Richardson Trough and Misty Creek Embayment, Yukon Territory and District of Mackenzie, Canada

2006 ◽  
Vol 43 (12) ◽  
pp. 1791-1820 ◽  
Author(s):  
D E Jackson ◽  
A C Lenz
Keyword(s):  
Northwest Territories ◽  
Deep Water ◽  
Yukon Territory ◽  
Early Ordovician ◽  
The Road ◽  
Bedded Chert ◽  
First Occurrence ◽  
Mackenzie Mountains ◽  
First Time

Four graptolite biozones are recorded from the Arenig portion of the Road River Group in the Richardson and Mackenzie mountains in the Yukon and Northwest Territories. In ascending order, these zones are Tetragraptus approximatus, Pendeograptus fruticosus, Didymograptus bifidus, and Parisograptus caduceus australis (new). The Castlemainian stage may be represented by nongraptolitic massive bedded chert. The Arenig–Llanvirn boundary is drawn below the first occurrence of Undulograptus austrodentatus. Fifty-four graptolite taxa are present, and 16 of these species and subspecies are recorded for the first time in this deep-water biotope, namely, Didymograptus? cf. adamantinus, D. asperus, D. dilatans, D. cf. kurcki, D. validus communis, Holmograptus aff. leptograptoides, H. sp. A, Isograptus? sp. nov. A, I. ? dilemma, Keblograptus geminus, Pseudisograptus manubriatus harrisi, Ps. m. koi, Ps. m. janus, Ps. cf. tau, Xiphograptus lofuensis, and Zygograptus cf. abnormis.

scholarly journals Occurrence of Amblyomma rotundatum Koch, 1844 on Epicrates assisi Machado, 1945 in João Pessoa, Paraíba, Brazil

2021 ◽  
Vol 15 (4) ◽  
pp. 335-338
Author(s):  
Aksa Ingrid Vieira Batista ◽  
Gabriel Vinicius Carvalho de Lucena ◽  
Kleber Silva de Oliveira Filho ◽  
Thiago Ferreira Lopes Nery ◽  
Thiago Fernandes Martins ◽  
...  
Keyword(s):  
Host Species ◽  
Tick Species ◽  
Wide Distribution ◽  
Dorsal Region ◽  
Taxonomic Key ◽  
Caatinga Biome ◽  
First Occurrence ◽  
First Time ◽  
Semi Arid

The Caatinga rainbow boa (Epicrates assisi Machado, 1945) is a snake belonging to the order Squamata, family Boidae, and subfamily Boinae. It has a wide distribution in Brazil and can be found in the Caatinga biome. The present study aims to report the first occurrence of Amblyomma rotundatum on E. assisi in the municipality of João Pessoa, Paraíba State (PB). On March 3, 2020, a tick collection was performed on the dorsal region of the head of an E. assisi, which was captive at the Arruda Câmara Zoobotanical Park, João Pessoa-PB. After collecting the tick, it was transferred to a flask containing 70º alcohol and sent to the Laboratory of Animal Parasitology of the Federal Rural University of the Semi-Arid (UFERSA) for analysis. Identification was done with the aid of a stereomicroscope using a taxonomic key. The result identified this specimen as a nymph of A. rotundatum. The occurrence of this tick species on E. assisi is reported for the first time and constitutes new data applicable to the ectoparasites that occur in this host species in Brazil.

Enantioselective first total syntheses of the antiviral natural products xiamycins D and E

2021 ◽  
Vol 57 (81) ◽  
pp. 10644-10646
Author(s):  
Dattatraya H. Dethe ◽  
Manmohan Shukla
Keyword(s):  
Natural Products ◽  
Total Syntheses ◽  
First Time

The enantioselective first total syntheses of marine pentacyclic indolosesquiterpenoids xiamycins D (4) and E (5) have been described for the first time to the best of our knowledge.

Linuparus korura n. sp. (Decapoda: Palinura) from the Bortonian (Eocene) of New Zealand

1988 ◽  
Vol 62 (2) ◽  
pp. 245-250 ◽  
Author(s):  
Rodney M. Feldmann ◽  
Robert K. Bearlin
Keyword(s):  
New Zealand ◽  
Fossil Record ◽  
Middle Eocene ◽  
Species Comparison ◽  
Morphological Descriptors ◽  
First Occurrence ◽  
First Time ◽  
Pacific Species

Linuparus (Linuparus) korura n. sp. is described from Bortonian (middle Eocene) rocks in Otaio Gorge, South Canterbury, New Zealand. This discovery represents the first occurrence of the genus in New Zealand and the first notice of a fossil occurrence of the subgenus which is represented by three modern Indo-Pacific species. Comparison of key morphological descriptors suggests that L. korura is related to L. scyllariformis and L. trigonis. A stridulatory mechanism, similar to that seen on modern Linuparus, is described for the first time from the fossil record.

Chemical Constituents of the Lichen Cladina macaronesica

1991 ◽  
Vol 46 (1-2) ◽  
pp. 12-18 ◽  
Author(s):  
Antonio G . González ◽  
Jaime Bermejo Barrera ◽  
Elsa Ma Rodríguez Pérez ◽  
Consuelo E. Hernández Padrón
Keyword(s):  
Natural Products ◽  
Phenolic Compounds ◽  
Silver Nitrate ◽  
Silica Gel ◽  
Column Chromatography ◽  
Chemical Constituents ◽  
Usnic Acid ◽  
Acetone Extract ◽  
First Time

Column chromatography of the acetone extract of the lichen Cladina macaronesica (Sephadex LH-20, silica gel and silver nitrate-im pregnated silica gel) afforded eight triterpenes identified by chemical and spectral m eans. α-Amyrenone, lupenone, taraxerol, taraxerone and /so-arborinol acetate were isolated for the first time from lichens and (-)-usnic acid and five mononuclear phenolic compounds were also obtained, four for the first time as natural products. The possible transformation of perlatolic acid into these phenolic compounds is briefly outlined.

scholarly journals Mori Ramulus (Chin.Ph.)—the Dried Twigs of Morus alba L./Part 1: Discovery of Two Novel Coumarin Glycosides from the Anti-Hyperuricemic Ethanol Extract

Molecules ◽  
2019 ◽  
Vol 24 (3) ◽  
pp. 629
Author(s):  
Jianbiao Yao ◽  
Houhong He ◽  
Jin Xue ◽  
Jianfang Wang ◽  
Huihui Jin ◽  
...  
Keyword(s):  
Natural Products ◽  
Ethanol Extract ◽  
Accurate Method ◽  
Morus Alba ◽  
Strongly Correlated ◽  
Bioactive Constituents ◽  
Antiplatelet Aggregation ◽  
Pharmacologically Active ◽  
First Time ◽  
Tof Ms

In Traditional Chinese Medicine (TCM), Mori ramulus (Chin.Ph.)—the dried twigs of Morus alba L.—is extensively used as an antirheumatic agent and also finds additional use in asthma therapy. As a pathological high xanthine oxidase (XO, EC 1.1.3.22) activity is strongly correlated to hyperuricemy and gout, standard anti-hyperuremic therapy typically involves XO inhibitors like allopurinol, which often cause adverse effects by inhibiting other enzymes involved in purine metabolism. Mori ramulus may therefore be a promissing source for the development of new antirheumatic therapeutics with less side effects. Coumarins, one of the dominant groups of bioactive constituents of M. alba, have been demonstrated to possess anti-inflammatory, antiplatelet aggregation, antitumor, and acetylcholinesterase (AChE) inhibitory activities. The combination of HPLC (DAD) and Q-TOF technique could give excellent separating and good structural characterization abilities which make it suitable to analyze complex multi-herbal extracts in TCM. The aim of this study was to develop a HPLC (DAD)/ESI-Q-TOF-MS/MS method for the identification and profiling of pharmacologically active coumarin glycosides in Mori ramulus refined extracts for used in TCM. This HPLC (DAD)/ESI-Q-TOF-MS/MS method provided a rapid and accurate method for identification of coumarin glycosides—including new natural products described here for the first time—in the crude extract of M. alba L. In the course of this project, two novel natural products moriramulosid A (umbelliferone-6-β-d-apiofuranosyl-(1→6)-β-d-glucopyranoside) and moriramulosid B (6-[[6-O-(6-deoxy-α-l-mannopyranosyl)-β-d-glucopyranosyl]oxy]-2H-1-benzopyran-1-one) were newly discovered and the known natural product Scopolin was identified in M. alba L. for the first time.

Awaruite, iridian awaruite, and a new Ru-Os-Ir-Ni-Fe alloy from the Sakhakot-Qila complex, Malakand Agency, Pakistan

1981 ◽  
Vol 44 (334) ◽  
pp. 225-230 ◽  
Author(s):  
Zulfiqar Ahmed ◽  
J. C. Bevan
Keyword(s):  
Electron Microprobe ◽  
Microprobe Analysis ◽  
Electron Microprobe Analysis ◽  
Atomic Percent ◽  
First Occurrence ◽  
First Time ◽  
Different Parts

AbstractThe authors report the first occurrence of awaruite in Pakistan, in the Sakhakot-Qila ultramafites. Electron-microprobe analysis reveals a considerable variation in the compositions of awaruites from different parts of the complex. The presence of copper in awaruite, in amounts up to 5 atomic percent, is also reported for the first time. In one chromitite body, an iridian awaruite with up to 27 wt% of iridium occurs in association with ‘normal’ awaruite and a new Ru-Os-Ir-Ni-Fe alloy. The awaruites are discussed in relation to those from other localities.

scholarly journals Phytochemical Investigation and Anticonvulsant Activity of Paeonia parnassica Radix

2007 ◽  
Vol 2 (4) ◽  
pp. 1934578X0700200
Author(s):  
Marina Kritsanida ◽  
Prokopios Magiatis ◽  
Alexios-Leandros Skaltsounis ◽  
James P. Stables
Keyword(s):  
Natural Products ◽  
Spectral Data ◽  
Anticonvulsant Activity ◽  
Treatment Of Epilepsy ◽  
Phytochemical Investigation ◽  
First Time

Based on traditional reports of the use of plants of the genus Paeonia in the treatment of epilepsy, we have screened extracts of the roots of three Greek Paeonia species ( P. parnassica, P. mascula subsp. hellenica, P. clusii subsp. clusii) for anticonvulsant activity. This led to the identification of some interesting prophylactic anticonvulsant activity of the extracts of P. parnassica. From the roots of this species, seventeen compounds were subsequently isolated and identified. Amongst these, seven contained the characteristic cage-like terpenic skeleton that is found only in plants of the genus Paeonia. Two of the above products: 4- O-methylpaeoniflorin (1) and paeonidanin (2) are described for the first time as natural products. The structures of all compounds have been elucidated on the basis of their spectral data.

scholarly journals Triterpenoids and Sterols from the Stem of Alnus Formosana Burk

2006 ◽  
Vol 1 (4) ◽  
pp. 1934578X0600100 ◽  
Author(s):  
Chien-Kuang Chen ◽  
Shiou-Ling Tuh ◽  
Chung-Hsiung Chen ◽  
Chen-Meng Kuo ◽  
Shoei-Sheng Lee
Keyword(s):  
Natural Products ◽  
Betulinic Acid ◽  
Methanol Extract ◽  
Chemical Constituents ◽  
First Time ◽  
Soluble Fractions

The chemical constituents of the stem of Alnus formosana Burk. were investigated and sixteen known compounds, composed of eleven triterpenoids and five sterols, were isolated and characterized from the n-hexane- and chloroform-soluble fractions of the methanol extract. Of these, seven triterpenoids, lupeol, lupenone, betulinic acid, 3-O-acetylbetulinic acid, 3-O-acetylerythrodiol, 3-O-acetyloleanolic aldehyde, and taraxerone, were isolated for the first time from an Alnus species. The isolation of the five sterols, stigmastanone, stigmast-4-en-3-one, β-sitosterol, β-sitosteryl-β-D-glucoside, and stigmasta-3,6-dione, is also the first time that the presence of such natural products has been recorded for an Alnus species. Taraxerone and betulinic acid were the major non-polar constituents of the stem of A. formosana.

Sign in / Sign up

Export Citation Format

Share Document