Acylated flavonol diglucosides from Ammania auriculata

2015 ◽  
Vol 70 (1-2) ◽  
pp. 39-43 ◽  
Author(s):  
Mahmoud Nawwar ◽  
Nahla Ayoub ◽  
Mohamed El-Raey ◽  
Soumaya Zaghloul ◽  
Amani Hashem ◽  
...  
Keyword(s):  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Chemical Investigation ◽  
Conventional Methods

Abstract Chemical investigation of the extract of the whole Ammania auriculata plant resulted in the identification of 13 polyphenols, including the hitherto unknown flavonoids, kaempferol 3-O-β-(6″-galloylglucopyranoside)-7-O-β-glucopyranoside, and its quercetin analogue. The structures of all isolates were elucidated by conventional methods, spectroscopic analysis, including 1D and 2D NMR, and by HRESI-MS as well.

Glucosides from the Fresh Flowers of Juglans regia L. and Their Biological Evaluation

2019 ◽  
Vol 17 (1) ◽  
pp. 31-35
Author(s):  
Haibo Wang ◽  
Xikui Liu
Keyword(s):  
Spectroscopic Analysis ◽  
Juglans Regia ◽  
2D Nmr ◽  
Antibacterial Activities ◽  
Biological Evaluation ◽  
Chemical Investigation ◽  
Etoac Extract

The chemical investigation of the EtOAc extract of the fresh flowers of Juglans regia L. resulted in a new α-tetralonyl glucoside (1) and two known glucosides (2-3). The structure of the new compound was determined by extensive 1D and 2D NMR spectroscopic analysis and HRESIMS. The biological evaluation of the obtained glucosides showed that compound 1 and 3 displayed good antioxidant and antibacterial activities. These two compounds were identified as the main functional molecules in the fresh flowers of Juglans regia L.

Three New Di-O-glycosyl-C-glucosyl Flavones from the Leaves of Caesalpinia ferrea Mart.

2014 ◽  
Vol 69 (9-10) ◽  
pp. 357-362 ◽  
Author(s):  
Mahmoud Nawwar ◽  
Amani El-Mousallami ◽  
Sahar Hussein ◽  
Amani Hashem ◽  
Mona Mousa ◽  
...  
Keyword(s):  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Conventional Methods

Abstract Three hitherto unknown di-O-xylosyl-C-glycosyl flavones were isolated from the leaves of Caesalpinia ferrea. The structures of all isolated compounds were elucidated by conventional methods and spectroscopic analysis, including 1D and 2D NMR, as well as by HRESIMS.

scholarly journals Beauvericin K, a New Antifungal Beauvericin Analogue from a Marine-derived Fusarium sp

2016 ◽  
Vol 11 (12) ◽  
pp. 1934578X1601101 ◽  
Author(s):  
Xiuli Xu ◽  
Shujiang Zhao ◽  
Ying Yu ◽  
Zhengkun Chen ◽  
Huihui Shen ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Chemical Investigation ◽  
Significant Activity ◽  
Fusarium Sp ◽  
Nmr Methods

Chemical investigation of a Chinese collection of a marine-derived fungus, Fusarium sp., led to the characterization of beauvericin K, a new analogue of beauvericin. The structure of the new compound was elucidated by detailed spectroscopic analysis, including 1D and 2D NMR methods, and HRMS. Beauvericin K showed significant activity against the yeast Candida albicans with an IC50 value of 6.25 μg/mL.

Isolation of New Glycosides from Anemarrhena Asphodeloides Rhizome and Screening of their Anticancer Activity

2019 ◽  
Vol 16 (6) ◽  
pp. 474-477 ◽  
Author(s):  
Pham Van Khang ◽  
Nguyen Thi Hien Lan ◽  
Le Quang Truong ◽  
Mai Thi Minh Chau ◽  
Mai Xuan Truong ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Spectral Data ◽  
Cell Lines ◽  
Cancer Cell ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Ic50 Values ◽  
Nmr Techniques ◽  
Inhibitory Activities ◽  
Anemarrhena Asphodeloides

In this report, two new steroidal glycosides were isolated and determined from n-butanol fraction of A.asphodeloides. The structures were confirmed in comparison with the spectral data of known compounds by using different spectroscopic analysis approaches including 1D & 2D-NMR techniques and HRMS. The anti-proliferation screening against cancer cell lines A549 and HeLa indicated that compound 1 exhibited good inhibitory activities with IC50 values of 0.79 and 0.55 µg/mL, respectively.

scholarly journals Massiliamide, a cyclic tetrapeptide with potent tyrosinase inhibitory properties from the Gram-negative bacterium Massilia albidiflava DSM 17472T

2020 ◽  
Author(s):  
Andri Frediansyah ◽  
Jan Straetener ◽  
Heike Brötz-Oesterhelt ◽  
Harald Gross
Keyword(s):  
Absolute Configuration ◽  
Inhibitory Activity ◽  
Liquid Culture ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Negative Bacterium ◽  
Gram Negative ◽  
The Absolute ◽  
Potent Inhibitory Activity ◽  
Cyclic Tetrapeptide

AbstractA cyclic tetrapeptide, designated massiliamide, was isolated from the liquid culture of the Gram-negative bacterium Massilia albidiflava DSM 17472T. The structure was elucidated through extensive spectroscopic analysis, including HR-MS and 1D and 2D NMR experiments. The absolute configuration was determined using the Marfey´s method. Massiliamide showed potent inhibitory activity towards tyrosinase with an IC50 value of 1.15 µM and no cytotoxicity.

Two new defensive constituents from potato tubers (Solanum tuberosum)

2017 ◽  
Vol 72 (6) ◽  
pp. 393-396
Author(s):  
Liangyan Liu ◽  
Jun Han ◽  
Yong Shen
Keyword(s):  
Solanum Tuberosum ◽  
Late Blight ◽  
Quantum Chemical ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Moderate Activity ◽  
Potato Tubers ◽  
Mycelia Growth ◽  
Late Blight Disease ◽  
Blight Disease

AbstractTwo new defensive constituents, solatuberenol A (1) and 3-O-β-d-glucopyranosyl stigmasta-5(6),24(28)-diene (2), were isolated from the potato tubers (Solanum tuberosum) infected with late blight disease. Their structures were identified by extensive spectroscopic analysis, including HRMS, IR, UV, 1D/2D NMR, ECD and quantum chemical calculations. Compounds 1 and 2 showed moderate activity against Phytophthora infestans with mycelia-growth inhibition of 30.1% and 52.4%, respectively, at the concentration of 500 ppm.

scholarly journals Chemical Constituents of Cordyceps cicadae

2015 ◽  
Vol 10 (12) ◽  
pp. 1934578X1501001 ◽  
Author(s):  
Zhi-Bo Chu ◽  
Jun Chang ◽  
Ying Zhu ◽  
Xun Sun
Keyword(s):  
Amino Acids ◽  
Spectroscopic Analysis ◽  
Chemical Constituents ◽  
2D Nmr ◽  
Cordyceps Cicadae ◽  
Nmr Techniques ◽  
Dopamine Analogues

One new bifuran derivative (1), together with fourteen known compounds, were isolated from Cordyceps cicadae X. Q. Shing. The known compounds included nine nucleosides, uracil (2), uridine (3), 2′-deoxyuridine (4), 2′-deoxyinosine (5), guanosine (6), 2′-deoxyguanosine (7), thymidine (8), adenosine (9), and 2′-deoxyadenosine (10); three amino acids tryptophan (11), phenylalanine (12), and tyrosine (13); and two dopamine analogues N-acetylnoradrenaline (14) and its dimer, trans–2-(3′,4′-dihydroxyphenyl)-3-acetylamino-7-( N-acetyl-2″-amino-ethylene)-1,4-benzodioxane (15). Their structures were decisively elucidated by spectroscopic analysis, including 1D and 2D NMR techniques.

Isoquinoline Alkaloids from Corydalis taliensis

2007 ◽  
Vol 62 (9) ◽  
pp. 1199-1202 ◽  
Author(s):  
Ying-Rui Wu ◽  
You-Xing Zhao ◽  
Yu-Qing Liu ◽  
Jun Zhou
Keyword(s):  
Spectral Data ◽  
Spectroscopic Analysis ◽  
Chemical Investigation ◽  
Perennial Herb ◽  
Isoquinoline Alkaloids ◽  
Rheumatic Arthritis ◽  
Spectral Evidence

Corydalis taliensis Franch is a perennial herb used for treatment of rheumatic arthritis, toothache, and hepatitis. The chemical investigation of this plant resulted in the isolation of a new compound, named taliensineside (1). Its structure was identified on the basis of spectral evidence. In addition, thirteen known isoquinoline alkaloids (2 - 14) were isolated and identified by spectroscopic analysis and comparison of their spectral data with those reported previously.

scholarly journals Two New Piperazine-Triones from a Marine-Derived Streptomycetes sp. Strain SMS636

Marine Drugs ◽  
2019 ◽  
Vol 17 (3) ◽  
pp. 186 ◽  
Author(s):  
Xiuli Xu ◽  
Jiahui Han ◽  
Rui Lin ◽  
Steven Polyak ◽  
Fuhang Song
Keyword(s):  
Staphylococcus Aureus ◽  
Minimum Inhibitory Concentration ◽  
Secondary Metabolites ◽  
Deep Sea ◽  
Spectroscopic Analysis ◽  
Inhibitory Concentration ◽  
2D Nmr ◽  
Antibacterial Activities ◽  
Bacillus Calmette Guerin ◽  
Methicillin Resistant

Two new piperazine-triones lansai E and F (1, 2), together with four known secondary metabolites lansai D (3), 1-N-methyl-(E,Z)-albonoursin (4), imidazo[4,5-e]-1,2,4-triazine (5), and streptonigrin (6) were isolated from a deep-sea-derived Streptomycetes sp. strain SMS636. The structures of the isolated compounds were confirmed by comprehensive spectroscopic analysis, including HRESIMS, 1D and 2D NMR. Compound 4 exhibited moderate antibacterial activities against Staphylococcus aureus and methicillin resistant S. aureus (MRSA) with Minimum Inhibitory Concentration (MIC) values of 12.5 and 25 μg/mL, respectively. Compound 6 displayed significant antibacterial activities against S. aureus, MRSA and Bacillus Calmette-Guérin (BCG) with MIC values of 0.78, 0.78 and 1.25 μg/mL, respectively.

scholarly journals New Cyclopentyl Fatty Acid and Cyanohydrin Glycosides from Fruits of Hydnocarpus hainanensis

2017 ◽  
Vol 12 (2) ◽  
pp. 1934578X1701200
Author(s):  
Thanh Tra Nguyen ◽  
Bich Ngan Truong ◽  
Huong Doan Thi Mai ◽  
Marc Litaudon ◽  
Van Hung Nguyen ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Cytotoxic Activity ◽  
Cell Line ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
New Compounds ◽  
Line Compound

Three new compounds, hydnohainanic acid (1), and hydnohainanin A (2) and B (3) were isolated from the fruits of Hydnocarpus hainanensis (Achariaceae). Their structures were determined by spectroscopic analysis, including 2D NMR, and MS. Compounds 1-3 were evaluated for their cytotoxic activity against the KB cell line. Compound 1 had a moderate cytotoxicity with an IC50 value of 32.5 μg/mL, while the two remaining compounds did not exhibit inhibition, even at a concentration of 128 μg/mL.

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