Structure elucidation and antimicrobial activities of five compounds from Artemisia integrifolia L

2019 ◽  
Vol 74 (9-10) ◽  
pp. 275-278
Author(s):  
Qing-Hu Wang ◽  
Yan-Hua Xu ◽  
Wen-Qiang Bao ◽  
Bi-Le-Ge-Tu Pa ◽  
Jun-Sheng Hao
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Structure Elucidation ◽  
Antibacterial Activities ◽  
Antimicrobial Activities ◽  
Ionization Mass ◽  
Spectroscopic Methods ◽  
Two Dimensional ◽  
One Dimensional ◽  
Nmr Techniques

Abstract A new compound, integracid (1), together with four known compounds were isolated from the dichloromethane (CH2Cl2) extract from Artemisia integrifolia L. The structures of compounds (1–5) were elucidated by spectroscopic methods, including ultraviolet, infrared (IR), high resolution-electrospray ionization-mass spectrometry (HR-ESI-MS) and extensive one-dimensional (1D) and two-dimensional (2D) nuclear magnetic resonance (NMR) techniques, and by comparison with data reported in the references. Antibacterial activities of the compounds were evaluated against various bacteria.

scholarly journals A New Chlorinated Phenolic Compound From the Antarctic Lichen, Pertusaria dactylina

2020 ◽  
Vol 15 (3) ◽  
pp. 1934578X2090288
Author(s):  
Man H. Koo ◽  
Min J. Kim ◽  
Jae E. Seo ◽  
Ji H. Kim ◽  
Se J. Han ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Phenolic Compound ◽  
Fast Atom Bombardment ◽  
2D Nmr ◽  
Antimicrobial Activities ◽  
Inhibitory Effect ◽  
Two Dimensional ◽  
One Dimensional ◽  
The Antarctic

A new chlorinated phenolic compound, methyl-3-chloro-2-hydroxy-4-methoxy-6-pentylbenzoate (1) and 4 known compounds (2-5) were isolated from the Antarctic lichen, Pertusaria dactylina ( Pertusariaceae). The structure of the new compound was determined by means of One-dimensional and two dimensional nuclear magnetic resonance (1D and 2D NMR) and high-resolution fast atom bombardment mass spectrometry (HRFABMS) experiments. The antimicrobial activities of compounds 1 to 5 against Staphylococcus aureus and Candida albicans were evaluated. The results showed that compound 1 exhibited a weak inhibitory effect against C. albicans with an IC50 value of 67 ± 7 μg/mL.

scholarly journals New Iridoid Derivatives from the Fruits of Cornus officinalis and Their Neuroprotective Activities

Molecules ◽  
2019 ◽  
Vol 24 (3) ◽  
pp. 625 ◽  
Author(s):  
Lin-lin Ji ◽  
Xin Wang ◽  
Jin-jie Li ◽  
Xiang-jian Zhong ◽  
Bo Zhang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Cell Damage ◽  
Neuroprotective Activity ◽  
Ultraviolet Spectroscopy ◽  
Spectroscopic Methods ◽  
Two Dimensional ◽  
One Dimensional ◽  
Cornus Officinalis ◽  
Ethanolic Extracts

Three previously undescribed iridoids, cornusfurals A–C, were isolated from the ethanolic extracts of fruits of Cornus officinalis. Their structures were elucidated by spectroscopic methods, including one-dimensional and two-dimensional nuclear magnetic resonance, ultraviolet spectroscopy, infrared spectroscopy, and mass spectrometry. The neuroprotective activity was evaluated by measuring corticosterone-induced damage in PC12 cells. The results showed that cornusfural B decreased corticosterone-induced PC12 cell damage compared with that in model cells.

scholarly journals Triterpenoid Saponins From the Root Bark of Haplocoelum congolanum

2019 ◽  
Vol 14 (5) ◽  
pp. 1934578X1985136 ◽  
Author(s):  
David Pertuit ◽  
Anne-Claire Mitaine-Offer ◽  
Tomofumi Miyamoto ◽  
Chiaki Tanaka ◽  
Duy Khang Tran ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Spectroscopic Methods ◽  
Root Bark ◽  
Two Dimensional ◽  
Triterpenoid Saponins ◽  
One Dimensional ◽  
Nuclear Magnetic

Two undescribed triterpenoid saponins together with 5 known ones were isolated from the root bark of Haplocoelum congolanum Hauman. Their structures were elucidated by spectroscopic methods including one-dimensional and two-dimensional nuclear magnetic resonance experiments in combination with mass spectrometry as 3- O-(4- O-[3-hydroxy-3-methylglutaryl])-α-l-arabinopyranosyl-(1→3)-α-l-rhamnopyranosyl-(1→2)-[β-d-glucopyranosyl-(1→4)]-α-l-arabinopyranosyloleanolic acid and 3- O-α-l-arabinofuranosyl-(1→3)-α-l-rhamnopyranosyl-(1→2)-[β-d-glucopyranosyl-(1→4)]-α-l-arabinopyranosyloleanolic acid.

scholarly journals A new tetracyclic diterpenoid from the seeds of Euphorbia lathyris

2020 ◽  
Vol 44 (5-6) ◽  
pp. 322-325
Author(s):  
Lie-Feng Ma ◽  
Yue Zhang ◽  
Xuan Zhang ◽  
Meng-Jia Chen ◽  
Zha-Jun Zhan ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
High Resolution ◽  
Spectroscopic Data ◽  
Resonance Spectroscopy ◽  
Ionization Mass ◽  
Two Dimensional ◽  
Detailed Interpretation ◽  
A Minor ◽  
Euphorbia Lathyris

Eupholathone, a minor diterpenoid with an unusual tetracyclic skeleton, was obtained from the seeds of Euphorbia lathyris, along with two known lathyrane diterpenoids, euphorbia factors L2 and L3. The structure of eupholathone was elucidated by detailed interpretation of its spectroscopic data, especially two-dimensional nuclear magnetic resonance spectroscopy and high-resolution electrospray ionization mass spectrometry.

scholarly journals Novel Pyran Derivative Ornamented with free Amino and Nitrile Functionalities: Synthesis and Spectroscopic Characterization

2019 ◽  
Vol 9 (1S3) ◽  
pp. 278-282
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Free Amino ◽  
Spectroscopic Characterization ◽  
Spectroscopic Methods ◽  
Two Dimensional ◽  
Spectral Techniques ◽  
One Dimensional ◽  
One Step ◽  
Pyran Derivative

A novel 4H-pyran derivative tethered with free amino and nitrile groups (1) was synthesized from commercially available meta-bromobenzaldehyde, malononitrile and 2-(methacryloyloxy)ethyl 3-oxobutanoate by adopting a one-step three components reaction strategy. The structure of the synthesized 1 has been established based on physical and spectroscopic methods such as infrared, one dimensional proton and carbon nuclear magnetic resonance as well as two-dimensional HSQC and HMBC spectral techniques.

scholarly journals Antibacterial and Antifungal Sesquiterpenoids from Aerial Parts of Anvillea garcinii

Molecules ◽  
2020 ◽  
Vol 25 (7) ◽  
pp. 1730 ◽  
Author(s):  
Shagufta Perveen ◽  
Jawaher Alqahtani ◽  
Raha Orfali ◽  
Hanan Y. Aati ◽  
Areej M. Al-Taweel ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Spectroscopic Analysis ◽  
Antimicrobial Properties ◽  
Ionization Mass ◽  
Two Dimensional ◽  
One Dimensional ◽  
Aerial Parts ◽  
Pathogenic Microbes ◽  
Antibacterial And Antifungal ◽  
New Metabolites

Two new sesquiterpenoids belonging to the guaiane, 4α,9α,10α-trihydroxyguaia-11(13)en-12,6α-olide (1), and germacrane, 9β-hydroxyparthenolide-9-O-β-D-glucopyranoside (2), classes have been isolated from the leaves of the Saudi medicinal plant Anvillea garcinii along with seven known compounds (3–9). The structures of the new metabolites were elucidated by spectroscopic analysis, including one-dimensional (1D) and two-dimensional (2D) Nuclear Magnetic Resonance (NMR) and high-resolution electrospray ionization mass spectrometry (HR-ESIMS). The antimicrobial properties of 1–9 were screened against seven different pathogenic microbes, and compounds 1–3 showed a potent antifungal activity.

The Structure Elucidation and Antimicrobial Activities of Nonsterol Triterpenoids from Ixeris chinensis

2014 ◽  
Vol 69 (9-10) ◽  
pp. 1021-1025 ◽  
Author(s):  
Qing-Hu Wang ◽  
Na-Ren-Chao-Ke-Tu Han ◽  
Na-Yin-Tai Dai ◽  
Xiao-Lan Wu ◽  
Wen-Quan Tai ◽  
...  
Keyword(s):  
Petroleum Ether ◽  
Structure Elucidation ◽  
Petroleum Ether Extract ◽  
2D Nmr ◽  
Antimicrobial Activities ◽  
Spectroscopic Methods ◽  
Ether Extract ◽  
Esi Ms ◽  
Nmr Techniques ◽  
First Time

Abstract An investigation of the petroleum ether extract from Ixeris chinensis Nakai has led to the isolation of a new compound, 3-O-acetyl-22,28-cyclobauer-7-en-3β-ol (1), together with four known compounds which have been isolated from this plant for the first time, namely taraxast-20-en-3β-ol (2), 3-O-acetyl-taraxast-20-en-3β-ol (3), taraxast-20(30)-en-3β-ol (4), and 3-O-acetyl-taraxast-20(30)- en-3β-ol (5). The structures of the isolated compounds have been elucidated on the basis of spectroscopic methods including UV, IR, ESI-MS, 1D NMR, 2D NMR techniques, and by comparison with data reported in the literature. All compounds have been evaluated for their activity against various bacteria and shown to give good results

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