scholarly journals Prevalence and Risk Factors for Chronic Kidney Disease in Family Relatives of a Cameroonian Population of Hemodialysis Patients: A CrossSectional Study

2019 ◽  
Vol 4 (1) ◽  
pp. 12-17
Author(s):  
Mazou Ngou Temgoua ◽  
Gloria Ashuntantang ◽  
Marie José Essi ◽  
Joël Nouktadie Tochie ◽  
Moussa Oumarou ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Fasting Blood Glucose ◽  
Hemodialysis Patients ◽  
Biological Data ◽  
Sub Saharan Africa ◽  
Herbal Remedies ◽  
Maintenance Hemodialysis ◽  
Number Of Patients

Background: In sub-Saharan Africa (SSA), the trend in the number of patients admitted for maintenance hemodialysis is on the rise. The identification of risk factors for chronic kidney disease (CKD) ensures adequate primary and secondary preventive measures geared at reducing the burden of CKD in low-resource settings. A family history of CKD is an established risk factor for CKD in high-income countries. However, data on family predisposition to CKD is scarce in the literature on SSA. Objective: The current study aimed to determine the prevalence and risk factors of CKD in family relatives of a Cameroonian population of hemodialysis patients (HDP) followed-up in a major hemodialysis referral center in Cameroon. Methods: The current cross-sectional study was conducted over four months on a consecutive sample of first-degree family relatives of end-stage renal disease patients undergoing maintenance hemodialysis at the hemodialysis unit of the General Hospital of Yaoundé. For each participating family relative, socio-demographic characteristics, clinical data, and biological data including fasting blood glucose, proteinuria, and serum creatinine were collected. Results: A total of 82 first-degree family relatives of HDP were recruited. The prevalence of CKD among the participants was 15.8%. The main identified risk factors for CKD were age (P = 0.0015), female gender (P = 0.0357), hypertension (P = 0.0004), regular intake of herbal remedies (P = 0.0214), and diabetes mellitus (P = 0.0019). Conclusion: Overall, the current findings suggest an urgent need for population education, routine screening of CKD, and the identification of risk factors in first-degree family relatives of HDP in Cameroon.

scholarly journals The Prevalence of Helicobacter Pylori Infection in Patients with Chronic Kidney Disease Undergoing Hemodialysis

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Batric Babovic ◽  
Srdjan Djuranovic ◽  
Olgica Mihaljevic ◽  
Katarina Sakic ◽  
Jelena Borovinic Bojovic ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Helicobacter Pylori ◽  
Kidney Disease ◽  
Hemodialysis Patients ◽  
Helicobacter Pylori Infection ◽  
Maintenance Hemodialysis ◽  
Histopathological Analysis ◽  
Dialysis Duration ◽  
Control Subjects ◽  
Duodenal Lesions

Abstract The aim of this study was to analyze the prevalence of Helicobacter pylori infection and gastroduodenal lesions in Montenegrin patients with chronic kidney disease on hemodialysis. The study included 55 hemodialysis patients with dyspeptic symptoms and 50 control subjects with normal kidney function who had also dyspepsia. After dyspepsia assessment by an interview, all subjects underwent gastroduodenoscopy and histopathological analysis of biopsy specimens, taken from the corpus and antrum of the stomach. Helicobacter pylori was confirmed in 50.9% of corpus mucosa i.e. 60.6% of antrum mucosa of maintenance hemodialysis patients. There were no significantly differences in endoscopic findings of the stomach and bacterial presence between the two study groups of participants (p = 0.451), while duodenal lesions were prevalent in control subjects (p < 0.001). The atrophy of corpus mucosa was more common in hemodialysis patients (p = 0.007), especially in those who have been on hemodialysis for a longer time (p < 0.001) and had lower pH (p = 0.011). The prevalence of Helicobacter pylori infection shown an inverse relationship with dialysis duration. Contrary, a positive relationship between Helicobacter pylori and the concentration of bicarbonate was demonstrated (p = 0.031). The prevalence of Helicobacter pylori and atrophic mucosal changes in Montenegrin hemodialysis patients depends on dialysis duration and acid-base balance.

scholarly journals Community-Based Screening for Chronic Kidney Disease, Hypertension and Diabetes in Dharan

2013 ◽  
Vol 52 (189) ◽  
pp. 205-212 ◽  
Author(s):  
Sanjib Kumar Sharma ◽  
Subodh Dhakal ◽  
Lekhjung Thapa ◽  
Anup Ghimire ◽  
Rikesh Tamrakar ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Intervention Program ◽  
Lifestyle Modification ◽  
Fasting Blood Glucose ◽  
Management Program ◽  
Community Based ◽  
Spot Urine

Introduction: Nepal cannot afford renal replacement therapy for End Stage Renal Disease due to lack of resources. Early diagnosis of Chronic Kidney Disease and its risk factors may reduce the need of renal replacement therapy.Methods:A community-based screening on, 3218 people ≥20 years were assessed by door-to-door survey in Dharan, Nepal. Health status, lifestyle habit, physical examination and blood pressure were evaluated. Spot urine was examined for proteins and glucose by dipstick. Fasting blood glucose and serum creatinine were measured in a subset of 1000 people and the prevalence of Chronic Kidney Disease was evaluated.Results: Overweight, obesity, hypertension, diabetes and proteinuria were found in 20%, 5.0%, 38.6%, 7.5%, and 5.1% respectively. In the subset group, Chronic Kidney Disease was detected in 10.6%. Multivariate analysis indicated age (P <0.0001) and diabetes (P = 0.027) as statistically significant predictors for Chronic Kidney Disease. Total of 848 patients entered the management program of lifestyle modification and pharmacologic intervention. Glycemic and blood pressure control was achieved in 60% and 72%, respectively. Regression or stabilization of proteinuria was reported in 52% of patients. Conclusions: Burden of Chronic Kidney Disease and cardiovascular risk factors are high in Dharan. Reasonable control of blood sugar, hypertension and proteinuria was achieved in this program. Findings indicate that activation a large prevention and intervention program to tackle Chronic Kidney Disease and Cardiovascular Disease in Nepal is needed.Keywords: chronic kidney disease; community-screening; diabetes; hypertension; intervention; Nepal.

scholarly journals Prevalence and determinants of chronic kidney disease in urban adults’ populations of northern Cameroon: a cross-sectional study

2019 ◽  
Author(s):  
Francois Folefack Kaze ◽  
Mahamat Maimouna ◽  
Augustin Fanday Beybey ◽  
Eric Walter Pefura-Yone ◽  
Adamou Dodo Balkissou ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Herbal Medicines ◽  
Sub Saharan Africa ◽  
Cluster Sampling ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Major Health Problem ◽  
Chronic Nephropathy

Abstract Background: Chronic kidney disease (CKD) is a major health problem with growing prevalence in sub-Saharan Africa. We present the prevalence and determinants of CKD in Garoua and Figuil cities of the North region of Cameroon. Methods: A cross-sectional survey was conducted from January to June 2018 in the two cities, using a multi-level cluster sampling. All adults with low estimated glomerular filtration rate (eGFR) (< 60 ml/min/1.73 m2) by Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation and/or albuminuria (≥ 30 mg/g) were reviewed three months later. Logistic regression models (accounting for the sampling strategy) were used to investigate the predictors of the outcomes. Results: A total of 433 participants were included, with a mean age (95%CI) of 45.0 (43.4-46.6) years, 212 (48.7%) men, 294 (67.9%) from Garoua and 218 (45.6%) with no formal education. Risk factors for chronic nephropathy were highly prevalent including longstanding use of street medications (52.8%), herbal medicines (50.2%) and non-steroidal anti-inflammatory drugs (50%), alcohol consumption (34.4%), hypertension (33.9%), overweight/obesity (33.6%), hyperuricemia (16.8%), smoking (11.3%) and hyperglycemia (6.5%). The prevalence of CKD was 11.7% overall, 10.7% in Garoua and 13% in Figuil participants. Equivalents figures for CKD G3-5 and albuminuria were 2.8%, 2.0% and 4.5%; and 9.1%, 9.3% and 8.5% respectively. History of diabetes, increase systolic blood pressure, hyperglycemia and hyperuricemia were predictors of CKD. Conclusion: The prevalence of CKD is as high in these northern cities as previously reported in southern cities of Cameroon, driven mostly by known modifiable risk factors of chronic nephropathy.

Nutritional risk factors among hemodialysis patients with Chronic kidney disease (West Algeria) Sidi-Bel

2016 ◽  
Vol 6 (4) ◽  
pp. 119-123
Author(s):  
Fatima Hamara ◽  
Karima Bereksi Reguig ◽  
Abdelhamid Bedjaoui ◽  
Abbes Bouterfas
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Daily Intake ◽  
Hemodialysis Patients ◽  
Significant Rise ◽  
Nutritional Risk ◽  
Biological Parameters ◽  
Dietary Recommendations ◽  
West Algeria

The purpose of this study was to examine the nutritional status among the subjects attained by chronic kidney disease The overall included sample con-tained a group of 391 patients, hospitalized for hemodialysis at the nephro-logy division of the Hassani Abdelkader CHU Sidi-Bel-Abbes in the Western of Algeria. The obtained results indicated that men 57.69 % were more affected that women 42.30 % with a sex ratio of 1.36. The chronic kidney disease was more prevalent among older range 47 years. The biological parameters de-monstrated no significant rise of the urea amount with a rate of 2.20 ± 1.04 (g/l) among men and 1.98 ± 1.02 (g/l) among women. The average of creatininemy was approximatively 110.75 ± 56.49 (mg/l) for men 97.01 ± 48.47 (mg/l) for women. The creatinin clearance is 10.33 ± 7.95 (ml/min/1.73 m2) for man and 9.15 ± 6.29 (ml/min/1.73 m2) for woman. In addition, the glo-merular flow of filtration was decreased at the two sexes and confirms a disturbance of the renal function. The correlation between serum of creati-nine and clearance in both sexes is important for both men R = 0.458 and women: R = 0.731. The relation is inversely proportional between creatinine and clearance values. The evaluation of food consumption, indicates that daily intake energy exceeds dietary recommendations, characterized by overconsumption lipid and carbohydrate and protein deficiency. Intakes of vitamins are usually covered. But the mineral intake is not covered. Overall, healthcare is essential for the present population to prevent serious compli-cations of this disease.

scholarly journals Prevalence of chronic kidney disease and risk factors in North-Central Nigeria: a population-based survey

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Timothy Olusegun Olanrewaju ◽  
◽  
Ademola Aderibigbe ◽  
Ademola Alabi Popoola ◽  
Kolawole Thomas Braimoh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Management Strategies ◽  
Central Zone ◽  
Population Based ◽  
Sub Saharan Africa ◽  
Middle Income ◽  
North Central ◽  
Kidney Length

Abstract Background Chronic kidney disease (CKD) is a growing challenge in low- and middle-income countries, particularly in sub-Saharan Africa. There is insufficient population-based data on CKD in Nigeria that is required to estimate its true burden, and to design prevention and management strategies. The study aims to determine the prevalence of CKD and its risk factors in Nigeria. Methods We studied 8 urban communities in Kwara State, North-Central zone of Nigeria. Blood pressure, fasting blood sugar, urinalysis, weight, height, waist circumference and hip circumference were obtained. Albuminuria and kidney length were measured by ultrasound while estimated glomerular filtration rate (eGFR) was derived from serum creatinine, using chronic disease epidemiology collaboration (CKD-EPI) equation. Associations of risk factors with CKD were determined by multivariate logistic regression and expressed as adjusted odds ratio (aOR) with corresponding 95% confidence intervals. Results One thousand three hundred and fifty-three adults ≥18 years (44% males) with mean age of 44.3 ± 14.4 years, were screened. Mean kidney lengths were: right, 93.5 ± 7.0 cm and left, 93.4 ± 7.5 cm. The age-adjusted prevalence of hypertension was 24%; diabetes 4%; obesity 8.7%; albuminuria of > 30 mg/L 7%; and dipstick proteinuria 13%. The age-adjusted prevalence of CKD by estimated GFR < 60 ml/min/1.73m2 and/or Proteinuria was 12%. Diabetes (aOR 6.41, 95%CI = 3.50–11.73, P = 0.001), obesity (aOR 1.50, 95%CI = 1.10–2.05, P = 0.011), proteinuria (aOR 2.07, 95%CI = 1.05–4.08, P = 0.035); female sex (aOR 1.67, 95%CI = 1.47–1.89, P = 0.001); and age (aOR 1.89, 95%CI = 1.13–3.17, P = 0.015) were the identified predictors of CKD. Conclusions CKD and its risk factors are prevalent among middle-aged urban populations in North-Central Nigeria. It is common among women, fueled by diabetes, ageing, obesity, and albuminuria. These data add to existing regional studies of burden of CKD that may serve as template for a national prevention framework for CKD in Nigeria. One of the limitations of the study is that the participants were voluntary community dwellers and as such not representative for the community. The sample may thus have been subjected to selection bias possibly resulting in overestimation of CKD risk factors.

scholarly journals МОДИФІКАЦІЯ ФАКТОРІВ РИЗИКУ СЕРЦЕВО-СУДИННИХ УСКЛАДНЕНЬ В ПЛАНІ ОПТИМІЗАЦІЇ ЛІКУВАННЯ ХВОРИХ ІЗ ХРОНІЧНОЮ ХВОРОБОЮ НИРОК СЕАНСАМИ ПРОГРАМНОГО ГЕМОДІАЛІЗУ

2014 ◽  
Author(s):  
I. L. Kuchma
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Cardiovascular Complications ◽  
National Registry ◽  
Treatment Programs ◽  
Number Of Patients ◽  
Class 1 ◽  
Therapy Sessions

<p class="1">The number of patients with chronic kidney disease (CKD) in substitution therapy sessions dialysis program in Ukraine is growing. Improvement of methods of renal replacement therapy (RRT), chronic kidney disease, in particular, the use of modern dialysis technology has led to a significant increase in the life expectancy of patients. However, the mortality of the disease remains high. In its structure heavily reliant on cardiovascular disease, according to the National registry of patients with chronic kidney disease in 2011 it was 72 %. In this regard, there is actual determination of risk factors for these complications and the search for new methods to ensure their prevention. The author studied the effect of individually tailored and standard hemodialysis treatment programs on the risk factors of cardiovascular complications in patients with CKD. It is concluded that the custom-fitted options at the time of hemodialysis and ultrafiltration properties klirensovyh dialyzer electrolyte composition of the dialysate can achieve better results in the management of risk factors in patients with CKD.</p>

scholarly journals Prevalence of Cardiovascular Risk Factors among Chronic Kidney Disease Patients Undergoing Hemodialysis in a Tertiary Care Center, Kathmandu, Nepal

2019 ◽  
Vol 21 (4) ◽  
pp. 313-318
Author(s):  
A Pokhrel ◽  
P. Gyawali ◽  
BR Pokhrel ◽  
M P Khanal ◽  
D N Manandhar ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Cardiovascular Risk ◽  
Calcium Phosphate ◽  
Kidney Disease ◽  
Care Center ◽  
Tertiary Care ◽  
Maintenance Hemodialysis ◽  
Tertiary Care Center ◽  
Phosphate Product

The risk of cardiovascular disease is higher in chronic kidney disease patients compared to the general population and its impact is higher in developing countries compared to the developed countries. With this background in mind, we aimed to evaluate the prevalence of different cardiovascular risk factors in patients on maintenance hemodialysis in a tertiary care center. Chronic kidney disease patients aged 18 years and above who were under maintenance hemodialysis in the hemodialysis unit of Nepal Medical College were included in the study. Pre-dialysis venous blood samples from the participants were collected and analyzed for serum calcium, phosphorus, total protein, albumin and hemoglobin. Calcium phosphate product was calculated. Out of 100 study participants, 52% were male and 48% were female. Age-wise distribution showed 38% of the participants were below 40 years. The mean age of the participants was 45.86 ± 14.4 years. Ninety-three percent had hypertension and 29% had diabetes mellitus. Hypocalcemia was present in 80%, hyperphosphatemia was seen among 81% and high calcium phosphate product was present in 33% of the participants. Low hemoglobin (< 10gm/dL) was found in 86%. The cardiovascular risk trend in the Nepalese chronic kidney disease population is fairly different compared to the western population. Participants were younger. Prevalence of hypertension and diabetes was high. The high prevalence of anemia might be due to unaffordability of the participants for regular erythropoietin therapy. Inadequately managed hyperphosphatemia despite the widespread use of phosphorus binders, is still a major clinical challenge in patients on hemodialysis.

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