scholarly journals Comparison the effect of high flux and low flux dialyzer on quality of life in hemodialysis patients; a clinical trial

2018 ◽  
Vol 8 (2) ◽  
pp. 98-105 ◽  
Author(s):  
Khodayar Oshvandi ◽  
Mehri Safari ◽  
Mahmood Gholyaf ◽  
Abbas Moghim-Beygi ◽  
Farshid Shamsaei ◽  
...  

Introduction: End-stage renal disease (ESRD) is a worldwide public health problem. ESRD reduces health-related quality of life. Quality of life is an important determinant in the mortality and morbidity of hemodialysis patients. However, several studies have suggested that high flux dialyzers increase dialysis adequacy and reduce mortality and morbidity in these patients. Objectives: This study aimed to investigate the effects of high flux and low flux dialyzers on the quality of life in hemodialysis patients. Patients and Methods: In this clinical trial, 93 patients who met the inclusion criteria were randomly assigned to two groups of high flux and low flux dialyzers. Before intervention, both groups filled demographic and quality of life questionnaires. They were undergone dialysis with two dialyzers (one group by high flux and another by low flux) three times a week for 6 weeks. Then quality of life questionnaire was filled by both groups once again. Results: The overall quality of life score was not significantly different in both groups before intervention (P=0.121). After intervention, however, high flux group attained a significantly higher mean score (54 ± 10.4) than low flux group (43.89 ± 11.64) (P<0.001). Conclusion: According to the results of this study, the use of high flux dialyzers can be a useful method to increase the quality of life in hemodialysis patients.

2020 ◽  
Vol 12 (3) ◽  
Author(s):  
Mahmoudreza Peyravi ◽  
Mehdi Amirkhani ◽  
Faeze Abadi ◽  
Ali Abbasijahromi ◽  
Shima Sheidaie ◽  
...  

Background: Nowadays, the quality of life of hemodialysis patients has decreased, which doubled the need for educational interventions. Objectives: The current study investigated the effect of positive thinking training on different dimensions of quality of life of hemodialysis patients. Methods: This is a controlled clinical trial study conducted on 70 hemodialysis patients in Fasa, Fars province, in 2019. The patients were selected using the simple sampling method. Then, they were divided into two groups of intervention (n = 35) and control (n = 35). After obtaining informed consent, the researchers asked the participants to complete the SF-36 Quality of Life Questionnaire. The intervention group was trained positive thinking skills in 8 workshop sessions; each lasted for 90 minutes. Data were analyzed using SPSS version 20. To analyze the data, statistical tests such as chi-square, Kolmogorov-Smirnov, independent, and t-test were used. Results: The mean and standard deviation of the patients’ quality of life in the intervention group increased from 35.95 ± 10.07 to 55.98 ± 11.71 (P < 0.001). The changes in patients’ quality of life before and after the intervention were also assessed in 8 dimensions, which showed that the quality of life of the patients did not change significantly in terms of physical function (P = 0.42) and physical pain (P = 0.62), but for other dimensions, it was significantly increased (P < 0.001). Conclusions: Positive thinking training improved the quality of life of hemodialysis patients, particularly in the dimensions of the emotional role, emotional health, energy and vitality, social performance, and general health is recommended.


2017 ◽  
Vol 33 (S1) ◽  
pp. 82-83
Author(s):  
Julie Jones-Diette ◽  
Ros Wade ◽  
Kath Wright ◽  
Alexis Llewellyn ◽  
Stephen Rice ◽  
...  

INTRODUCTION:Primary hyperhidrosis has no discernible cause and is characterised by uncontrollable excessive and unpredictable sweating, which occurs at rest, regardless of temperature. The symptoms of hyperhidrosis can significantly affect quality of life, and can lead to social embarrassment, loneliness, anxiety and depression.The aim of this literature review was to identify the tools used to measure quality of life in studies of hyperhidrosis. Patient advisors provided insight and their perspective.METHODS:Studies were identified through searches undertaken in January 2016. The search strategies combined topic terms for hyperhidrosis with a recognised search filter for “quality of life”. All studies that reported measuring quality of life or described a quality of life measure/tool in the context of primary hyperhidrosis were included. The information on the tools and their use in hyperhidrosis was summarized in a narrative synthesis. Patient advisors contributed to the interpretation of the findings.RESULTS:The review included 184 studies and many studies used multiple tools. Twenty-two individual tools were identified. The review identified disease specific, dermatology specific, and general health/utility tools. The most commonly identified tools were the Dermatology Life Quality Index (DLQI), the Hyperhidrosis Disease Severity Scale (HDSS), and the Hyperhidrosis Quality of Life Questionnaire (HQLQ). The Hyperhidrosis Quality of Life index (HidroQoL©) is recently designed and validated, and therefore was used only in its validation study.When asked about these four quality of life tools patient advisors agreed that the HidroQoL© tool covered disease-specific quality of life dimensions relevant to them most comprehensively and was easy to complete. The DLQI was considered to be too general and too focussed on the skin. The HDSS was considered to be too basic and not sufficiently discriminating.CONCLUSIONS:Future studies of the effectiveness of interventions for hyperhidrosis on health-related quality of life may benefit from including the HidroQoL© tool.


2018 ◽  
Vol 8 (1) ◽  
pp. 22-27 ◽  
Author(s):  
Mahin Naderifar ◽  
Mansoureh Zagheri Tafreshi ◽  
Mahnaz Ilkhani ◽  
Magid Reza Akbarizadeh ◽  
Fereshteh Ghaljaei

Introduction: Institutionalizing adherence to treatment in hemodialysis patients is one of the important nursing goals for improving quality of life in these patients. Adherence to treatment approach in these patients can play a pivotal role in improving the health level and feeling of well-being. Objectives: This study aimed at determining the quality of life in hemodialysis patients presenting to hemodialysis centers affiliated to Shahid Beheshti University of Medical Sciences, Tehran, Iran, on the basis of adherence to treatment. Patients and Methods: This is a correlational descriptive-analytic study. The study population consisted of hemodialysis patients in five hospitals affiliated to Shahid Beheshti University of Medical Sciences, Tehran, in 2017. The data were collected during 8 months from October 2016 to May 2017 in Tehran. A sample volume of 200 patients was determined in this study. Demographic information questionnaire, KDQOL-SF, and ESRD-AQ were applied in data collection. Availability sampling method was used to select the samples on the basis of inclusion criteria. The data were analyzed with SPSS version 18 using descriptive and inferential statistics. Results: Our findings showed that 50% of the patients were male. Most of the respondents of the study (23%) were 51-60 years old. The results indicated that the mean score of quality of life of patients was 50.42±22.81. The mean total score of adherence to treatment was 901.13±85.30. Also, the correlation coefficient in this study revealed a significant correlation between total score of quality of life and adherence to treatment (r=0.218, P<0.01). Conclusion: Considering the significant correlation between adherence to treatment and life quality of patients, healthcare providers can promote the life quality of these patients via focusing on planning programs for emphasizing the role of education and interventions that improve adherence to treatment in these patients.


2016 ◽  
Vol 2 (4) ◽  
pp. 291
Author(s):  
Evangelia Prevyzi ◽  
Georgios Argyriou ◽  
Thomai Kollia ◽  
Athanasia Nestor ◽  
Anastasia Kotanidou ◽  
...  

Introduction: Dialysis affects the quality of life of hemodialysis patients due on idrasis in physical activities, psychological factors, and social adaptability.  Predominant indicator for assessing the adequacy of dialysis, considered the Kt / V (clearance time/volume of distribution). According to international guidelines, the price which shows adequate dialysis is > 1.2. Aim: The aim of the present study was the association of quality of life of hemodialysis patients with adequate dialysis. Material and Methods: To evaluate the quality of life of hemodialysis patients used the questionnaire KDQOL-SF weighted in the Greek language and the Greek egkyropoiimeno population. Excluded from the study patients with a speaking disability, those who were comatose, aliens, and those undergoing dialysis 3 hours/ 2 times / week. For data processing, used the statistical package SPSS ver.17. Results: Based on the statistical analysis t-test results showed respect to the route of vascular access that patients with graft (31,6%)   had a higher clearance rate adequacy, as well as patients undergoing hemodialysis with high permeability (high-flux) filters (35,8%) and those undergoing dialysis with hemodiafiltration (35,8%).According to the statistical criterion pearson's r and multivariate analysis of linear regression, statistically significant difference was only between Kt / V and forefinger encouraging staff and p = 0,032 and p = 0,015 respectively.Conclusions: The conclusions drawn from this study showed that there was no correlation between quality of life and dialysis adequacy, but only with the index of encouraging staff.


2017 ◽  
Vol 54 (1) ◽  
pp. 27-32 ◽  
Author(s):  
Émerson Soares PONTES ◽  
Ana Karênina de Freitas Jordão do AMARAL ◽  
Flávia Luiza Costa do RÊGO ◽  
Elma Heitmann Mares AZEVEDO ◽  
Priscila Oliveira Costa SILVA

ABSTRACT BACKGROUND The elderly population faces many difficulties as a result of the aging process. Conceptualize and evaluate their life quality is a challenge, being hard to characterize the impact on daily activities and on functional capacity. The stroke is one of the most disabling neurological diseases, becoming a public health problem. As an aggravating result, there is dysphagia, a disorder that compromises the progression of the food from the mouth to the stomach, causing clinical complications to the individual. OBJECTIVE Characterize the life quality of the elderly swallowing affected by stroke. METHODS Cross-sectional study conducted at the University Hospital, attended by 35 elderly with stroke, being 19 women and 16 men, with age between 60 and 90 years old, that self-reported satisfactory overall clinical picture. It was applied the Quality of Life Swallowing protocol. The data were statistically analyzed, by means of ANOVA tests, Spearman correlation, t test, with significance level of 5%. RESULTS The mean age was 69.5 years; as for the scores obtained by the 35 participants in the 11 domains of the protocol, it was observed a change in score indicating severe to moderate impact in quality of life related to self-reported swallowing (31.8% to 59.5%); the domain that most interfered was the feeding time (31.8%). CONCLUSION Elderly affected by stroke that present dysphagia has low scores in quality of life related to swallowing.


2020 ◽  
Vol 49 (4) ◽  
pp. 468-478 ◽  
Author(s):  
Rathika Krishnasamy ◽  
Carmel M. Hawley ◽  
Meg J. Jardine ◽  
Matthew A. Roberts ◽  
Yeoungjee Cho ◽  
...  

Background: A new class of dialysis membrane, the mid cut-off (MCO) dialyzer, has been developed to improve the clearance of uremic toxins in hemodialysis (HD). The a tRial Evaluating Mid cut-Off Value membrane clearance of Albumin and Light chains in HemoDialysis patients (REMOVAL-HD) study aimed to determine if regular use of MCO dialyzer was safe and specifically did not result in a significant loss of albumin. Methods: This investigator initiated, crossover, longitudinal, device study was conducted across 9 centers in Australia and New Zealand (n = 89). Participants had a 4-week wash-in with high-flux HD, followed by 24-week intervention with MCO HD and a subsequent 4-week wash-out with high-flux HD. The primary outcome was change in serum albumin between weeks 4 and 28. Secondary outcomes included trends in serum albumin, changes in kappa- and lambda-free light chains (FLC), 6-min walk test (6MWT), malnutrition inflammation score (MIS), restless legs score and quality of life. Results: Participants had a mean age of 66 ± 14 years, 62% were men, 45% were anuric, and 51% had ­diabetes. There was no reduction in serum albumin following treatment with MCO HD (mean reduction –0.7 g/L, 95% CI –1.5 to 0.1). A sustained, unexplained reduction in serum albumin (>25%) was not observed in any participant. A reduction in FLC was observed 2 weeks into MCO HD (lambda-FLC: Δ –9.1 mg/L, 95% CI –14.4 to –3.7; kappa-FLC: Δ –5.7 mg/L, 95% CI –9.8 to –1.6) and was sustained for the rest of the study intervention. Both FLC increased after the cessation of MCO use. There was no improvement in restless legs symptoms, quality of life, 6MWT or MIS scores. Conclusions: Regular HD using the MCO dialyzer did not result in a significant fall in serum albumin. There were no effects on quality of life, functional status or nutrition. Trial Registration: Australian New Zealand Clinical Trials Registry Number (ANZCTRN) 12616000804482.


Renal Failure ◽  
2012 ◽  
Vol 35 (2) ◽  
pp. 216-221 ◽  
Author(s):  
Konstantia Kantartzi ◽  
Stelios Panagoutsos ◽  
Efthemia Mourvati ◽  
Athanasios Roumeliotis ◽  
Konstantinos Leivaditis ◽  
...  

1992 ◽  
Vol 12 (6) ◽  
pp. 412-418 ◽  
Author(s):  
David N. Churchill ◽  
Daniel R. Bird ◽  
Wayne Taylor ◽  
Mary Louise Beecroft ◽  
Joanne Gorman ◽  
...  

Cephalalgia ◽  
1997 ◽  
Vol 17 (8) ◽  
pp. 867-872 ◽  
Author(s):  
NC Santanello ◽  
AB Polis ◽  
SL Hartmaier ◽  
MS Kramer ◽  
GA Block ◽  
...  

A validated migraine-specific questionnaire (24-h Migraine Quality of Life Questionnaire1: 24-h MQoLQ) was used to assess the impact of migraine and migraine therapy on health related quality of life during an acute migraine attack. Male and female migraineurs aged 18-55 years were randomized to placebo ( n = 41), rizatriptan 2.5 mg ( n = 47), 5 mg ( n = 74), or 10 mg ( n = 85) in a triple-blind, placebo-controlled clinical trial. Rizatriptan 5 mg and 10 mg were significantly more efficacious than placebo on pain relief and functional disability. After accounting, for multiple comparisons to placebo, rizatriptan 10 mg showed significantly better responses compared to placebo on three of five domains of 24-h MQoLQ (social functioning, migraine symptoms, and feelings/concerns). The O'Brien's Rank Sum Test statistic showed a statistically significant overall difference on the 24-h MQoLQ between the 10 mg rizatriptan and placebo groups ( p = 0.005) and for the overall close trend ( p 0.001).


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