scholarly journals Modele myślenia teologicznego

2020 ◽  
Vol 6 ◽  
pp. 147-161
Author(s):  
Aneta Krupka ◽  
Keyword(s):  
Personal Experience ◽  
Complex Structure ◽  
Methodological Challenges ◽  
Correct Understanding ◽  
Theological Thinking

The article attempts to present the advantages of using models in theology in the context of contemporary methodological challenges. The use of renewed hermeneutics can help to reorganize theological thinking to avoid both treating the content of faith in a matter-of-fact manner and reducing it to personal experience. At the same time, fruits of this thinking can be presented in the form of theological models that are simplified representations of a more complex structure. They must not be overly reductive but as holistic, multifaceted, dynamic, and practical as possible. One of the important proposals is the nuptial model developed by Cardinal Angelo Scola. Using this model seems to be inspiring when applied to support, among other things, the correct understanding of sacramentology.

IMPRESSION AS A PROBLEM IN MILITARY PSYCHOLOGY

2019 ◽  
pp. 161-175
Author(s):  
M. Papucha
Keyword(s):  
Personal Experience ◽  
Psychological Problem ◽  
Reference Points ◽  
Human Cognition ◽  
Military Operations ◽  
Military Psychology ◽  
Individual Character ◽  
Enormous Amount ◽  
Correct Understanding ◽  
Research Analysis

Psychological problem of an impression seems to be one of the most important problems in military psychology, its correct understanding will mean successful reference-points both in military operations and in coping with consequences of participation in hostilities, particularly PTSD. We consider concept of «impression» as an artifact which has absorbed enormous amount of nuances of values and senses. It took its place within subtle process of human cognition of one’s own internal world. Research analysis must provide answers about psychological essence of impression, its origin, further fate, disappearance and connections with other elements of psyche. We cannot agree with concept of an impression being referred as an image. In any case, even if we can speak about an image (focus on spontaneity and integrity of an impression is definitely suitable here), then it couldn’t be neither visual nor auditory; even if the impression is an image, then it is an amodal image of the world (A. N. Leontiev). Impressions occur to be related to perception, but at the same time are not reduced to the latter. An impression has very close and obvious relations to emotions and feelings. Experience indicates about pronounced individual character of impressions. It is reflected in the fact that not every complex irritant can facilitate emergence of one’s impression. On the other hand, different people in the same impression-causing situation can get very different impressions. Impressions remain as memory traces and personal experience accumulators.

scholarly journals Ευθανασία: Ηθικά διλήμματα πολιτισμικής αυτοσυνειδησίας

Bioethica ◽  
2017 ◽  
Vol 3 (2) ◽  
pp. 81
Author(s):  
Κωνσταντίνος Κορναράκης (Konstantinos Kornarakis)
Keyword(s):  
Palliative Care ◽  
End Of Life ◽  
Personal Experience ◽  
Fear Of Death ◽  
Patient’S Autonomy ◽  
Theological Thinking

This paper focuses on the anthropological background of Euthanasia’s cultural profile, claiming that a cultural reception of Euthanasia should previously deal with anthropological questions such as patient’s autonomy and its relation to existential freedom, the fear of death, the meaning of personal experience of pain in shaping one’s own freedom and the cardinal importance of community’s role in patient’s palliative care. The theological thinking can contribute in this interscientific dialogue on the end of life, re-opening the question of the ontology of person and consequently the question of eschatology.

A new method of complex structure analysis by electron microscopy

1978 ◽  
Vol 36 (1) ◽  
pp. 628-629
Author(s):  
V.V. Rybin ◽  
E.V. Voronina
Keyword(s):  
Complex Structure ◽  
Reciprocal Lattice ◽  
Stacking Faults ◽  
Plastic Strains ◽  
Base Position ◽  
Structural Regularity ◽  
Orientation Matrix ◽  
Computerized Processing ◽  
Fully Automatic ◽  
Diffraction Patterns

Recently, it has become essential to develop a helpful method of the complete crystallographic identification of fine fragmented crystals. This was maainly due to the investigation into structural regularity of large plastic strains. The method should be practicable for determining crystallographic orientation (CO) of elastically stressed micro areas of the order of several micron fractions in size and filled with λ>1010 cm-2 density dislocations or stacking faults. The method must provide the misorientation vectors of the adjacent fragments when the angle ω changes from 0 to 180° with the accuracy of 0,3°. The problem is that the actual electron diffraction patterns obtained from fine fragmented crystals are the superpositions of reflections from various fragments, though more than one or two reflections from a fragment are hardly possible. Finally, the method should afford fully automatic computerized processing of the experimental results.The proposed method meets all the above requirements. It implies the construction for a certain base position of the crystal the orientation matrix (0M) A, which gives a single intercorrelation between the coordinates of the unity vector in the reference coordinate system (RCS) and those of the same vector in the crystal reciprocal lattice base : .

Computer processing of high-resolution images of periodic specimens

1986 ◽  
Vol 44 ◽  
pp. 2-5
Author(s):  
W. Chiu ◽  
M.F. Schmid ◽  
T.-W. Jeng
Keyword(s):  
High Resolution ◽  
Fourier Transforms ◽  
Complex Structure ◽  
Distribution Functions ◽  
Multiple Image ◽  
Cryo Electron Microscopy ◽  
Structure Factors ◽  
Unit Cells ◽  
High Resolution Images ◽  
Phase Probability Distribution

Cryo-electron microscopy has been developed to the point where one can image thin protein crystals to 3.5 Å resolution. In our study of the crotoxin complex crystal, we can confirm this structural resolution from optical diffractograms of the low dose images. To retrieve high resolution phases from images, we have to include as many unit cells as possible in order to detect the weak signals in the Fourier transforms of the image. Hayward and Stroud proposed to superimpose multiple image areas by combining phase probability distribution functions for each reflection. The reliability of their phase determination was evaluated in terms of a crystallographic “figure of merit”. Grant and co-workers used a different procedure to enhance the signals from multiple image areas by vector summation of the complex structure factors in reciprocal space.

A large rotating structure around AB Doradus A at VLBI scale

2019 ◽  
Vol 15 (S354) ◽  
pp. 189-194
Author(s):  
J. B. Climent ◽  
J. C. Guirado ◽  
R. Azulay ◽  
J. M. Marcaide
Keyword(s):  
Magnetic Reconnection ◽  
Main Sequence ◽  
Complex Structure ◽  
Main Sequence Star ◽  
Polar Cap ◽  
Vlbi Observations ◽  
Rotating Structure ◽  
Source Structure ◽  
Expected Position

AbstractWe report the results of three VLBI observations of the pre-main-sequence star AB Doradus A at 8.4 GHz. With almost three years between consecutive observations, we found a complex structure at the expected position of this star for all epochs. Maps at epochs 2007 and 2010 show a double core-halo morphology while the 2013 map reveals three emission peaks with separations between 5 and 18 stellar radii. Furthermore, all maps show a clear variation of the source structure within the observing time. We consider a number of hypothesis in order to explain such observations, mainly: magnetic reconnection in loops on the polar cap, a more general loop scenario and a close companion to AB Dor A.

SAC3B is a target of CML19, the centrin 2 of Arabidopsis thaliana

2020 ◽  
Vol 477 (1) ◽  
pp. 173-189 ◽  
Author(s):  
Marco Pedretti ◽  
Carolina Conter ◽  
Paola Dominici ◽  
Alessandra Astegno
Keyword(s):  
Excision Repair ◽  
Complex Structure ◽  
Binding Motif ◽  
C Terminus ◽  
Repair Protein ◽  
Nucleotide Excision ◽  
Ef Hand ◽  
Molecular Determinants ◽  
Structure In Solution

Arabidopsis centrin 2, also known as calmodulin-like protein 19 (CML19), is a member of the EF-hand superfamily of calcium (Ca2+)-binding proteins. In addition to the notion that CML19 interacts with the nucleotide excision repair protein RAD4, CML19 was suggested to be a component of the transcription export complex 2 (TREX-2) by interacting with SAC3B. However, the molecular determinants of this interaction have remained largely unknown. Herein, we identified a CML19-binding site within the C-terminus of SAC3B and characterized the binding properties of the corresponding 26-residue peptide (SAC3Bp), which exhibits the hydrophobic triad centrin-binding motif in a reversed orientation (I8W4W1). Using a combination of spectroscopic and calorimetric experiments, we shed light on the SAC3Bp–CML19 complex structure in solution. We demonstrated that the peptide interacts not only with Ca2+-saturated CML19, but also with apo-CML19 to form a protein–peptide complex with a 1 : 1 stoichiometry. Both interactions involve hydrophobic and electrostatic contributions and include the burial of Trp residues of SAC3Bp. However, the peptide likely assumes different conformations upon binding to apo-CML19 or Ca2+-CML19. Importantly, the peptide dramatically increases the affinity for Ca2+ of CML19, especially of the C-lobe, suggesting that in vivo the protein would be Ca2+-saturated and bound to SAC3B even at resting Ca2+-levels. Our results, providing direct evidence that Arabidopsis SAC3B is a CML19 target and proposing that CML19 can bind to SAC3B through its C-lobe independent of a Ca2+ stimulus, support a functional role for these proteins in TREX-2 complex and mRNA export.

Crystal structures of Magnaporthe oryzae trehalose-6-phosphate synthase (MoTps1) suggest a model for catalytic process of Tps1

2019 ◽  
Vol 476 (21) ◽  
pp. 3227-3240 ◽  
Author(s):  
Shanshan Wang ◽  
Yanxiang Zhao ◽  
Long Yi ◽  
Minghe Shen ◽  
Chao Wang ◽  
...  
Keyword(s):  
Crystal Structures ◽  
Conformational Changes ◽  
Magnaporthe Oryzae ◽  
Structural Information ◽  
Complex Structure ◽  
Critical Role ◽  
Catalytic Process ◽  
Structural Basis ◽  
Salt Bridges ◽  
Terminal Domain

Trehalose-6-phosphate (T6P) synthase (Tps1) catalyzes the formation of T6P from UDP-glucose (UDPG) (or GDPG, etc.) and glucose-6-phosphate (G6P), and structural basis of this process has not been well studied. MoTps1 (Magnaporthe oryzae Tps1) plays a critical role in carbon and nitrogen metabolism, but its structural information is unknown. Here we present the crystal structures of MoTps1 apo, binary (with UDPG) and ternary (with UDPG/G6P or UDP/T6P) complexes. MoTps1 consists of two modified Rossmann-fold domains and a catalytic center in-between. Unlike Escherichia coli OtsA (EcOtsA, the Tps1 of E. coli), MoTps1 exists as a mixture of monomer, dimer, and oligomer in solution. Inter-chain salt bridges, which are not fully conserved in EcOtsA, play primary roles in MoTps1 oligomerization. Binding of UDPG by MoTps1 C-terminal domain modifies the substrate pocket of MoTps1. In the MoTps1 ternary complex structure, UDP and T6P, the products of UDPG and G6P, are detected, and substantial conformational rearrangements of N-terminal domain, including structural reshuffling (β3–β4 loop to α0 helix) and movement of a ‘shift region' towards the catalytic centre, are observed. These conformational changes render MoTps1 to a ‘closed' state compared with its ‘open' state in apo or UDPG complex structures. By solving the EcOtsA apo structure, we confirmed that similar ligand binding induced conformational changes also exist in EcOtsA, although no structural reshuffling involved. Based on our research and previous studies, we present a model for the catalytic process of Tps1. Our research provides novel information on MoTps1, Tps1 family, and structure-based antifungal drug design.

Personal Experience As a Motivating Factor for Sexual Assault Education, Advocacy, and/or Support Work

2014 ◽  
Author(s):  
Rebecca E. Kason ◽  
Grace Akinrinade ◽  
Rebekah Halpert ◽  
Thomas P. Demaria
Keyword(s):  
Sexual Assault ◽  
Personal Experience ◽  
Motivating Factor ◽  
Support Work
Sign in / Sign up

Export Citation Format

Share Document