Metabolic surgery with Roux-en-y Gastric bypass is an effective treatment in patients with Familial Partial Lipodystrophy and Body Mass Index Less than 35 kg/m2

2016 ◽  
Author(s):  
Claire Adams ◽  
David Savage ◽  
Lisa Gaff ◽  
Catherine Flanagan ◽  
Charlotte Jenkins-Liu ◽  
...  

2014 ◽  
Vol 6 (1) ◽  
pp. 1 ◽  
Author(s):  
Mário Nora ◽  
Marta Guimarães ◽  
Rui Almeida ◽  
Paulo Martins ◽  
Gil Gonçalves ◽  
...  


2020 ◽  
Vol 16 (4) ◽  
pp. 503-508 ◽  
Author(s):  
Daniel Horwitz ◽  
Christina Padron ◽  
Timothy Kelly ◽  
John K. Saunders ◽  
Aku Ude-Welcome ◽  
...  


2019 ◽  
Vol 21 (12) ◽  
pp. 2660-2666 ◽  
Author(s):  
Raffaella Gentilella ◽  
Giorgio Sesti ◽  
Luis Vazquez ◽  
Hélène Sapin ◽  
Victoria Reed ◽  
...  


2001 ◽  
Vol 101 (9) ◽  
pp. A-93
Author(s):  
L. Frisch ◽  
J. O'Sullivan-Maillet ◽  
R. Touger-Decker ◽  
S. VonHagen


2020 ◽  
Vol 2020 ◽  
pp. 1-6 ◽  
Author(s):  
Mohsen Mahmoudieh ◽  
Behrouz Keleidari ◽  
Naser Afshin ◽  
Masoud Sayadi Shahraki ◽  
Shahab Shahabi Shahmiri ◽  
...  

Introduction. Obesity is among the newest health matters that human beings are struggling with. Length of bypassed intestine is important in achievement of most weight loss and least nutritional and absorptive disorders. This study has aimed to assess short-term metabolic and nutritional effects of laparoscopic mini-gastric bypass/one anastomosis gastric bypass (MGB/OAGB) with a loop bypass length of 180 centimeters (cm) and compare these factors among patients with a body mass index (BMI) of 40–45 and 45–50 kilograms per square meter (kg/m2). Methods. 25 patients were put in group 1 (BMI = 40–45 kg/m2) and 25 patients in group 2 (BMI = 45–50 kg/m2). Patients’ BMI, postoperative weight, excess weight loss, and laboratory tests including fasting blood sugar (FBS), lipid profile, serum iron (Fe), ferritin, total iron-binding capacity (TIBC), 25-OH vitamin D, vitamin B12, liver function tests, and albumin were recorded preoperatively and within 3- and 6-month follow-up. Results. Weight loss and BMI reduction was significantly more in patients with higher BMI level (P=0.007), and excess weight loss was higher in patients with lower preoperative BMI level (P=0.007). Six-month follow-up showed statistically significant reduction in total cholesterol, total triglyceride, Fe, and vitamin B12 among patients with higher BMI level (P value <0.05). Conclusion. Based on this study, 180-cm intestinal bypassed length works for patients with a BMI level of 40–45 and 45–50 kg/m2, according to their significant decrease in weight, BMI, and improving glycolipid profile.



2008 ◽  
Vol 74 (6) ◽  
pp. 469-475 ◽  
Author(s):  
Ronald H. Clements ◽  
Kishore Yellumahanthi ◽  
Mary Wesley ◽  
Naveen Ballem ◽  
Kirby I. Bland

Hyperparathyroidism (HPT) can occur after gastric bypass because of the alteration in vitamin D and calcium absorption. Adequate serum vitamin D concentrations have not been clearly defined in this patient population. Vitamin D (Vit D) and parathyroid hormone (PTH) were assessed 1 year after laparoscopic gastric bypass (LGB). The prevalence of HPT and Vit D deficiency were determined and their association was evaluated using Fisher's exact test. Ninety-three patients (aged 44 ± 1.1 years, 49.6 ± 0.67 kg/m2 body mass index, 79.6% female, 69.6% white) were evaluated. The prevalence of Vit D deficiency (less than 20 ng/mL) and HPT (greater than 65 pg/mL) was 23.6 per cent (n = 22) and 25.7 per cent (n = 28), respectively. Among patients with HPT, only eight of 28 (28.6%) had Vit D deficiency, and of those with Vit D deficiency, only eight of 22 (36.4%) had HPT. There was a weak inverse correlation (r = –0.37) between PTH and Vit D. Blacks are at higher risk for Vit D deficiency. There was no significant association between Vit D deficiency and HPT, Vit D deficiency and Roux limb length, or HPT and Roux limb length. After LGB, Vit D deficiency and hyperparathyroidism occur commonly. Body mass index and Roux limb length are not associated with these two conditions, but racial differences do exist. There is a weak inverse correlation between Vit D and PTH. Further research is needed to elucidate the causes, treatments, and significance of HPT after LGB.



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