Hyperparathyroidism and Vitamin D Deficiency after Laparoscopic Gastric Bypass

2008 ◽  
Vol 74 (6) ◽  
pp. 469-475 ◽  
Author(s):  
Ronald H. Clements ◽  
Kishore Yellumahanthi ◽  
Mary Wesley ◽  
Naveen Ballem ◽  
Kirby I. Bland
Keyword(s):  
Body Mass Index ◽  
Vitamin D ◽  
Gastric Bypass ◽  
Racial Differences ◽  
Body Mass ◽  
Laparoscopic Gastric Bypass ◽  
Serum Vitamin ◽  
Inverse Correlation ◽  
Limb Length ◽  
Roux Limb

Hyperparathyroidism (HPT) can occur after gastric bypass because of the alteration in vitamin D and calcium absorption. Adequate serum vitamin D concentrations have not been clearly defined in this patient population. Vitamin D (Vit D) and parathyroid hormone (PTH) were assessed 1 year after laparoscopic gastric bypass (LGB). The prevalence of HPT and Vit D deficiency were determined and their association was evaluated using Fisher's exact test. Ninety-three patients (aged 44 ± 1.1 years, 49.6 ± 0.67 kg/m2 body mass index, 79.6% female, 69.6% white) were evaluated. The prevalence of Vit D deficiency (less than 20 ng/mL) and HPT (greater than 65 pg/mL) was 23.6 per cent (n = 22) and 25.7 per cent (n = 28), respectively. Among patients with HPT, only eight of 28 (28.6%) had Vit D deficiency, and of those with Vit D deficiency, only eight of 22 (36.4%) had HPT. There was a weak inverse correlation (r = –0.37) between PTH and Vit D. Blacks are at higher risk for Vit D deficiency. There was no significant association between Vit D deficiency and HPT, Vit D deficiency and Roux limb length, or HPT and Roux limb length. After LGB, Vit D deficiency and hyperparathyroidism occur commonly. Body mass index and Roux limb length are not associated with these two conditions, but racial differences do exist. There is a weak inverse correlation between Vit D and PTH. Further research is needed to elucidate the causes, treatments, and significance of HPT after LGB.

scholarly journals Inverse correlation between high body mass index and response to cholecalciferol treatment in children with vitamin D deficiency

2021 ◽  
Vol 96 (2) ◽  
pp. 94-100
Author(s):  
Sahar Masoumi-Moghaddam ◽  
Samar Masoumi-Moghaddam ◽  
Seyed Alinaghi Kazemi ◽  
Saeideh Mazloomzadeh ◽  
Ahmad Jalilvand ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Body Mass ◽  
High Body Mass Index ◽  
Inverse Correlation ◽  
High Body

scholarly journals Comparison of Vitamin D Level among Vaccinated and Non Vaccinated Pregnant Women with Covid-19

2021 ◽  
Vol 15 (10) ◽  
pp. 3500-3502
Author(s):  
Saeeda Safi ◽  
Umme habiba ◽  
Shandana Mustafa Jadoon ◽  
Umbreen Idrees ◽  
Ayesha Aftab ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Vitamin D ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Body Mass ◽  
Gestational Age ◽  
Serum Vitamin ◽  
Serum Vitamin D ◽  
Group I ◽  
Group Ii

Objective: The aim of this study is to compare the vitamin D level among vaccinated and non-vaccinated pregnant women with COVID-19. Study Design: Observational/comparative study Place and Duration: The study was conducted at the department of Gynae and Obs Quaid-e-Azam International Hospital, Islamabad and Qazi Hussain Ahmad Medical Complex, Nowshera for Duration of six months from October 2020 to March 2021. Methods: Total 120pregnant women had coronavirus disease were presented. Informed written consent was taken for details demographics age, gestational age, parity and body mass index. 18-45years was the women ages. Patients were categorized into 2-groups. Group I had 60 vaccinated patients and in group II 60 non-vaccinated pregnant women. Blood sample of all the patients were taken for the level of serum 25-hydroxy vitaminD3 [25 (OH) D3]. Vitamin D deficiency was calculated and compared among both groups. Sufficient serum vitamin D level was considered >30ng/ml. SPSS 23.0 version was used to analyze complete data. Results: In group I age was 28.4±8.55 years with mean BMI 24.08±1.18 kg/m2 and in group II age was 27.41±6.37 years with mean body mass index 23.12±4.42 kg/m2. Mean gestation age in group I was 33.12±9.42 weeks and in group II mean gestational age was 34.07±5.63 weeks. Mean parity in group I was 3.88±7.27 and in group II 4.01±4.14 was mean parity. We found 28 (46.7%) primigravida cases in I-group and 30 (50%) primigravida females in II-group. In group I 51(85%) patients had vitamin D deficiency and in group II 54 (90%) had deficiency of vitamin D. Among 51 deficient women of group I, number of severe deficiency (<10ng/ml) women were 8 (13.3%), deficiency (10-20ng/ml) were 13 (21.7%) and not-sufficient (20-30ng/ml) were 30 (50%) and in group II prevalence of severity (<10ng/ml) patients were 10 (16.7%), deficient cases (10-20ng/ml) were 15 (25%) and not-sufficient cases (20-30ng/ml) were 29 (48.3%). Deficient vitamin D serum levels were 15.01±1.22 in group I and 14.34±4.12 in group II. Conclusion: In this study we concluded that prevalence of vitamin D deficiency was highly among pregnant women and most probably in non-vaccinated pregnant patients but did not find any significantly difference among both groups. Keywords: Pregnancy, COVID-19, Vitamin D, Vaccination

scholarly journals Body Mass Index, Vitamin D, and Type 2 Diabetes: A Systematic Review and Meta-Analysis

Nutrients ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1182 ◽  
Author(s):  
Shamaila Rafiq ◽  
Per Jeppesen
Keyword(s):  
Systematic Review ◽  
Body Mass Index ◽  
Vitamin D ◽  
Body Mass ◽  
Observational Studies ◽  
Meta Analysis ◽  
Serum Vitamin ◽  
Vitamin D Supplementation ◽  
Serum Vitamin D ◽  
Vitamin D Levels

The deficiency of vitamin D is prevalent all over the world. Studies have shown that vitamin D may play an important role in the development of obesity. The current study was conducted to quantitatively evaluate the association between serum 25-(OH) vitamin D levels and the risk of obesity in both diabetic and non-diabetic subjects. A systematic review and meta-analysis of observational studies was carried out for that purpose. We searched the Medline, PubMed, and Embase databases throughout all of March 2018. A total of fifty five observational studies for both diabetic and non-diabetic subjects were finally included in the meta-analysis. The data were analyzed by comprehensive meta-analysis software version 3 and the random effects model was used to analyze the data. The meta-analysis showed an overall inverse relationship between serum vitamin D status and body mass index (BMI) in studies of both diabetic (r = −0.173, 95% = −0.241 to −0.103, p = 0.000) and non-diabetic (r = −0.152, 95% = −0.187 to −0.116, p = 0.000) subjects. The evidence of publication bias was not found in this meta-analysis. In conclusion, the deficiency of vitamin D is associated with an increased level of BMI in the studies of both diabetic and non-diabetic subjects. Reliable evidence from well-designed future randomized controlled trials is required to confirm the findings from observational studies and to find out the potential regulatory effects of vitamin D supplementation to lower BMI.

Body Mass Index is Predictive of Higher In-hospital Mortality in Patients Undergoing Laparoscopic Gastric Bypass but Not Laparoscopic Sleeve Gastrectomy or Gastric Banding

2014 ◽  
Vol 80 (10) ◽  
pp. 1039-1043 ◽  
Author(s):  
James Villamere ◽  
Alana Gebhart ◽  
Stephen Vu ◽  
Ninh T. Nguyen
Keyword(s):  
Body Mass Index ◽  
Gastric Bypass ◽  
Sleeve Gastrectomy ◽  
Hospital Mortality ◽  
Gastric Banding ◽  
Body Mass ◽  
Laparoscopic Gastric Bypass ◽  
Complication Rates ◽  
Major Complications ◽  
The Impact

High body mass index (BMI) has been shown to be a factor predictive of increased morbidity and mortality in several single-institution studies. Using the University HealthSystem Consortium clinical database, we examined the impact of BMI on in-hospital mortality for patients who underwent laparoscopic gastric bypass, sleeve gastrectomy, and gastric banding between October 2011 and February 2014. Outcomes were examined within each procedure according to BMI groups of 35 to 49.9, 50.0 to 59.9, and 60.0 kg/m2 or greater. Outcome measures included in-hospital mortality, major complications, length of hospital stay, 30-day readmission, and cost. A total of 40,102 bariatric procedures were performed during this time period. For gastric bypass, there was an increase of in-hospital mortality (0.01 and 0.02 vs 0.34%; P < 0.01) and major complications (0.93 and 0.99 vs 2.62%; P < 0.01) in the BMI 60 kg/m2 or greater group. In contrast, sleeve gastrectomy and gastric banding had no association between BMI and rates of mortality and major complications. Cost increased with increasing BMI groups for all procedures. A strong association was found between BMI 60 kg/m2 or greater and higher in-hospital mortality and major complication rates for patients who underwent laparoscopic gastric bypass but not in patients who underwent sleeve gastrectomy or gastric banding.

scholarly journals Association of Body Mass Index with Serum Vitamin D and PSA Levels among Sudanese Prostate Cancer Patients

2021 ◽  
Vol 11 (6) ◽  
pp. 1-5
Author(s):  
Yousif Abdelhameed Mohammed ◽  
Ameer M Dafalla ◽  
Dafalla O Abuidris ◽  
Adam D. Abakar ◽  
A Mergani ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Body Mass Index ◽  
Vitamin D ◽  
Cancer Patients ◽  
Body Mass ◽  
Specific Antigen ◽  
Serum Vitamin ◽  
The United States ◽  
Serum Vitamin D ◽  
Vitamin D Levels

Background: Prostate cancer is the second most common cancer in men worldwide and the second leading cause of cancer deaths in men in the United States. Obesity has been consistently associated with lower 25-hydroxyvitamin D (25(OH)D) concentrations. Objectives: This cross-sectional study aimed to evaluate the serum vitamin D and PSA levels in Sudanese Obese and Non-Obese prostate cancer (PCa) attending the National Cancer Institute. Patients and Methods: Eighty six prostate cancer patients were included in this study, they were identified by clinical examination, histopathology and prostate-specific antigen (PSA). The mean age of them was 71.78 ± 8.04 years. Serum Vitamin D and PSA were measured by Electrochemiluminescence (ECL) immunoassay reactions using (Cobase411, serial No: 0868-16, manufactured by Hitachi high technologies corporation, Tokyo-Japan) the Elecsys reagents kit (Roche – Germany) Results: The means of serum vitamin D levels of among  obese was 35.5 ± 15.4 ng/dL and 38.4 ± 16.2 ng/dL  among non-obese group with non-significant differences(P=0.505). No significant association was observed between PSA levels and obese and non-obese (P=0.351). Vitamin D levels non-significantly negative correlated with BMI (r = -0.031, P = 0.778) and PSA (r = -0.062, P = 0.569), but there was insignificantly Positive correlated between PSA and vitamin D level (r = 0.151, P = 0.164). Conclusion: insignificant differences between vitamin D and serum PSA with BMI, Oral supplementation is recommended for individuals with low level of vitamin D. Keywords: Prostate cancer, Body mass index, Vitamin D, PSA, Sudanese.

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