A challenging case of progressive follicular thyroid cancer

2018 ◽  
Author(s):  
Shazia Hussain ◽  
Carmel Brennan ◽  
Nick Plowman ◽  
Kate Newbold ◽  
William Drake
Keyword(s):  
Thyroid Cancer ◽  
Follicular Thyroid Cancer

Abstract #1075 Metastatic Follicular Thyroid Cancer with Hemorrhagic Metastases to the Pituitary Gland

2018 ◽  
Vol 24 ◽  
pp. 258
Author(s):  
Regina Belokovskaya ◽  
Pietra Greenberg ◽  
Shira Saul
Keyword(s):  
Thyroid Cancer ◽  
Pituitary Gland ◽  
Follicular Thyroid Cancer

Abstract #1070 An Unusual Case of Metastatic Follicular Thyroid Cancer 40 Years After Initial Diagnosis

2018 ◽  
Vol 24 ◽  
pp. 255
Author(s):  
Lakshmi Menon ◽  
Yuanjie Mao ◽  
Sanaz Abedzadeh-Anaraki ◽  
Spyridoula Maraka
Keyword(s):  
Thyroid Cancer ◽  
Unusual Case ◽  
Initial Diagnosis ◽  
Follicular Thyroid Cancer

New markers of follicular thyroid cancer found with wide-panel next-generation sequencing

2018 ◽  
Author(s):  
Martyna Borowczyk ◽  
Ewelina Szczepanek-Parulska ◽  
Szymon Debicki ◽  
Bartlomiej Budny ◽  
Malgorzata Janicka-Jedynska ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Next Generation Sequencing ◽  
Next Generation ◽  
Follicular Thyroid Cancer ◽  
Generation Sequencing

Treating papillary and follicular thyroid cancer in children and young people: Single UK-center experience between 2003 and 2018

2020 ◽  
Author(s):  
Mechteld C de Jong ◽  
Mark N Gaze ◽  
Elwira Szychot ◽  
Virginia Rozalén García ◽  
Caroline Brain ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Young People ◽  
Follicular Thyroid Cancer ◽  
Children And Young People ◽  
Cancer In Children

Prognostic value of nuclear DNA content in papillary and follicular thyroid cancer

1988 ◽  
Vol 12 (4) ◽  
pp. 503-507 ◽  
Author(s):  
Jaap F. Hamming ◽  
Lodewijk J. D. M. Schelfhout ◽  
Cees J. Cornelisse ◽  
Cornelis J. H. van de Velde ◽  
Bernard M. Goslings ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Dna Content ◽  
Prognostic Value ◽  
Nuclear Dna ◽  
Nuclear Dna Content ◽  
Follicular Thyroid Cancer

scholarly journals Efficacy and Biomarker Analysis of Adavosertib in Differentiated Thyroid Cancer

Cancers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 3487
Author(s):  
Yu-Ling Lu ◽  
Ming-Hsien Wu ◽  
Yi-Yin Lee ◽  
Ting-Chao Chou ◽  
Richard J. Wong ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cell Lines ◽  
Differentiated Thyroid Cancer ◽  
Xenograft Model ◽  
In Vivo Studies ◽  
Follicular Thyroid Cancer ◽  
Biomarker Analysis ◽  
Cancer Tumor

Differentiated thyroid cancer (DTC) patients are usually known for their excellent prognoses. However, some patients with DTC develop refractory disease and require novel therapies with different therapeutic mechanisms. Targeting Wee1 with adavosertib has emerged as a novel strategy for cancer therapy. We determined the effects of adavosertib in four DTC cell lines. Adavosertib induces cell growth inhibition in a dose-dependent fashion. Cell cycle analyses revealed that cells were accumulated in the G2/M phase and apoptosis was induced by adavosertib in the four DTC tumor cell lines. The sensitivity of adavosertib correlated with baseline Wee1 expression. In vivo studies showed that adavosertib significantly inhibited the xenograft growth of papillary and follicular thyroid cancer tumor models. Adavosertib therapy, combined with dabrafenib and trametinib, had strong synergism in vitro, and revealed robust tumor growth suppression in vivo in a xenograft model of papillary thyroid cancer harboring mutant BRAFV600E, without appreciable toxicity. Furthermore, combination of adavosertib with lenvatinib was more effective than either agent alone in a xenograft model of follicular thyroid cancer. These results show that adavosertib has the potential in treating DTC.

Clonally Related But Phenotypically Divergent Human Cancer Cell Lines Derived from a Single Follicular Thyroid Cancer Recurrence (TT2609)

Thyroid ◽  
2001 ◽  
Vol 11 (10) ◽  
pp. 909-917 ◽  
Author(s):  
Albert A. Geldof ◽  
Richard T. Versteegh ◽  
Johan C. van Mourik ◽  
Martin A. Rooimans ◽  
Fre Arwert ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Recurrence ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Follicular Thyroid Cancer ◽  
Human Cancer Cell Lines ◽  
Thyroid Cancer Recurrence

INFORMATIVE VALUE OF SONOELASTOGRAPHY IN THE DIFFERENTIAL DIAGNOSIS OF FOLLICULAR THYROID CANCER

2021 ◽  
pp. 73-78
Author(s):  
Lyubov A. Timofeeva ◽  
Tatiana N. Aleshina ◽  
Marina E. Baranova ◽  
Marina A. Yusova ◽  
Natalia N. Nikolaeva
Keyword(s):  
Thyroid Cancer ◽  
Preoperative Diagnosis ◽  
Surgical Intervention ◽  
Ultrasound Examination ◽  
Shear Wave Elastography ◽  
Diagnostic Methods ◽  
Follicular Thyroid Cancer ◽  
Leading Role ◽  
Quantitative Characteristics ◽  
Multiparametric Ultrasound

In recent years, the opportunities of radiation diagnostic methods have stepped far ahead and today they play a leading role at the stage of preoperative diagnosis of thyroid diseases. The most promising of them is multiparametric ultrasound examination, as well as sonoelastography associated with it. Strain elastography and shear wave elastography make it possible to determine the boundaries of pathological formation and quantitative characteristics of nodular stiffness, which is important when determining the boundaries of invasive tumor growth, primarily thyroid cancer, when planning an upcoming surgical intervention. The article describes a clinical case of radiation diagnosis made for follicular thyroid cancer; it shows the importance of multiparametric ultrasound, including sonoelastography, in the early detection of thyroid cancer. A timely diagnosis and a correct chosen tactics for treating follicular thyroid cancer resulted in a favorable disease outcome.

Therapeutic outcome and prognosis in young patients with papillary and follicular thyroid cancer

2012 ◽  
Vol 28 (5) ◽  
pp. 489-494 ◽  
Author(s):  
Chung-Huei Huang ◽  
Tzu-Chieh Chao ◽  
Chuen Hseuh ◽  
Kun-Ju Lin ◽  
Tsung-Ying Ho ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Young Patients ◽  
Therapeutic Outcome ◽  
Follicular Thyroid Cancer
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